Life Extension News Archive

Biological age measured using popular epigenetic clocks vary by 3 years during the day

Live Forever Club - 23-Apr-2024

Schedule blood tests at the same time of day when tracking biological age over time

Some everyday medications could lengthen life, while others like opioids might pose risks

Live Forever Club - 22-Apr-2024

Surprisingly, metformin does not reduce death risk

Stem cells could potentially rejuvenate the thymus gland in older individuals

Live Forever Club - 21-Apr-2024

Potential tool in boosting immune function and combating the effects of ageing

Study reveals surprising telomere loss patterns in calorie restricted humans

Pennsylvania State University (PSU) - 17-Apr-2024

Complexities spark hope for health benefits beyond telomere length

Hevolution Foundation Announces Geroscience Research Opportunities (HF-GRO) Funding

Live Forever Club - 14-Apr-2024

Up to $2.5m per project to contribute to cutting-edge research in the field of ageing biology and geroscience

Silicon Valley startup aims to extend human lifespan with mitochondrial transplants

Live Forever Club - 12-Apr-2024

Research aims to extend lifespan and unlock new levels of human health

Body's repair system falters with age as stem cells lose their regenerative power

Live Forever Club - 12-Apr-2024

Machine learning reveals widespread decline in stem cell potency with age

NeuroSense raises $4.5M and partners with Lonza to combat neurodegenerative diseases

Longevity Technology - 12-Apr-2024

Funding fuels R&D, and collaboration focus on improving diagnosis and treatment options

Telomeres are different lengths than scientists previously thought

Phys.org - 11-Apr-2024

This could transform how we approach diseases linked to cell ageing

New drug prototype offers hope for repairing damaged lungs

EurekAlert! - 10-Apr-2024

The drug targets the lungs and activates stem cells

World's oldest man credits longevity to pure luck

The Guardian - 05-Apr-2024

John is right that supercentenarians tend to have a long life irrespective of their lifestyle

Juan Vicente Perez, the world's oldest man, dies at 114 in Venezuela

Sky News - 04-Apr-2024

The supercentenarian leaves behind a legacy of hard work, family, and faith

Antibody treatment rejuvenates aged immune systems in mice

Science - 04-Apr-2024

Researchers improved immune response to new infections and reduced overall inflammation

LyGenesis aims to grow a second liver within patient's own body

Interesting Engineering - 03-Apr-2024

Scientists injected liver cells into a patient's lymph node, aiming to create a "mini liver"

Paralyzed surfer regains mobility using stem cells in belly fat

Independent - 03-Apr-2024

Experimental stem cell therapy offers hope for spinal cord injury patients

Scientists found cholesterol eating bacteria in the gut

Broad Institute of MIT and Harvard - 02-Apr-2024

Some bacteria may hold key to lower cholesterol and heart disease risk

Urine-derived stem cells release anti-ageing molecules that changed mice ageing

Live Forever Club - 31-Mar-2024

The discovery reveals the body's potential for self-rejuvenation

Somatic mutations: Do these DNA changes hold the secrets to longevity?

Live Forever Club - 31-Mar-2024

The gradual buildup of DNA mutations may hold clues on how to combat age-related diseases

Andrew Steele's 9 tips on living a longer, healthier life

BBC Science Focus - 31-Mar-2024

The author of Ageless doesn't fall for the faddish approaches to slowing ageing but recommends things that actually work

Hevolution invests $20 million in Aeovian Pharmaceuticals to fight ageing

Longevity Technology - 28-Mar-2024

Funds to advance compounds that target mTORC1 pathway for treating rare and age-related conditions

ARPA-H program paves the way for on-demand organ transplants

Advanced Research Projects Agency for Health (ARPA-H) - 27-Mar-2024

Personalized bioprints for affordable and more accessible transplants in the near future

Naked mole-rats' genome unveils secrets of their heart health

Queen Mary University of London - 27-Mar-2024

Unique metabolism shields hearts in low-oxygen conditions, offering clues to human heart protection

Novel antibody therapy rejuvenates aging immune systems in mice

New Scientist - 27-Mar-2024

Potential treatment approach to boost immunity and fight disease in older adults

Sleeplessness can make you feel 10 years older, study finds

New Scientist - 27-Mar-2024

Getting enough sleep is the secret to feeling younger and healthier

Scientists overcome hurdles to design human artificial chromosomes

Singularity Hub - 26-Mar-2024

New technique delivers more genetic material, paving way for safer & effective gene therapies

Nanoscope's gene therapy offers hope for patients blinded by inherited retinal disease

FierceBiotech - 26-Mar-2024

Phase 2 trial results show significant vision improvement, plans for FDA approval

Ani Biome receives funding to personalise gut health treatments for longevity

Longevity Technology - 26-Mar-2024

Company will use machine learning and gut health science to create custom solutions

Lifespan.io interviews David Sinclair about his Information Theory of Aging and much more

Lifespan.io (LEAF) - 22-Mar-2024

Backup code: ageing cells from epigenetic changes could potentially be reset to a youthful state

US and UK adults experience higher midlife death rates compared to other nations

Oxford Population Health - 21-Mar-2024

Alarming trends in preventable deaths like drug overdoses, accidents, and suicides

Scientists successfully transplant genetically modified pig kidney into a living human

New Scientist - 21-Mar-2024

This procedure marks a major milestone in xenotransplantation

Loneliness and social isolation linked to faster aging and higher death risk

Mayo Clinic - 20-Mar-2024

New study finds social connections affect overall physical health and longevity

UCL study reveals cancer risk associated with vaping-induced DNA damage

Sky News - 20-Mar-2024

Study finds concerning similarities in DNA damage between vapers and smokers

Ultrahuman secures funding to expand its health monitoring platform

Longevity Technology - 20-Mar-2024

Company aims to revolutionize preventative healthcare using health tracking system

Gene therapy for rare brain disease sets a new pricing record at $4.25 million

FiercePharma - 20-Mar-2024

Its record-breaking price raises questions about affordability and access

Pandorum Technologies' develops potential cure for corneal blindness

Longevity Technology - 19-Mar-2024

Company's innovative "liquid cornea" technology shows promise in restoring vision

SENISCA secures 3.7 million euros to fight aging with RNA-based therapies

Longevity Technology - 18-Mar-2024

Developing senotherapeutics to target cellular senescence and treat age-related diseases

Extending quality life years: insights from the Global Healthspan Summit 2023

Live Forever Club - 16-Mar-2024

Event focused on extending quality life years through scientific innovation

UK study finds 14 prescription meds possibly linked to longer life

Lifespan.io (LEAF) - 15-Mar-2024

Viagra, cholesterol meds & estrogen replacements linked to longevity, but further research needed

Genomenon develops AI-powered tool to uncover links between genes and diseases

Inside Precision Medicine - 15-Mar-2024

This new technology could improve the accuracy of genetic testing

A new drug targeting liver cell growth shows excellent safety results in humans

HepaRegeniX GmbH - 15-Mar-2024

This could change the way we treat liver cancer and address transplant organ shortages

Ray Kurzweil brings his prediction of the technological singularity forward to 2029

Independent - 13-Mar-2024

Also predicts a new era of hybrid humans and the potential to reverse aging within the next five years

A new stem cell therapy could prevent amputations in limb ischemia

EurekAlert! - 13-Mar-2024

This innovative therapy uses a collagen microgel scaffold to improve stem cell survival

Jamie Justice provides an update on XPRIZE Healthspan competition entrants

Live Forever Club - 12-Mar-2024

Already over 200 organisations have pre-registered - this is going to be exciting to follow

Blood test decodes your aging clock: metabolites hold the key to staying young

UPMC - 11-Mar-2024

New discovery unveils a molecular fingerprint to predict biological age

Medical device bias hurts women and people with darker skin tones

BBC - 11-Mar-2024

Urgent action needed to tackle bias in pulse oximeters, AI devices & genetic tests for fair healthcare for all

Transplanted cells age at different rates depending on the host's age

Live Forever Club - 05-Mar-2024

Bodies of younger people could potentially rejuvenate older transplanted cells

Cell malfunctions can cause information leakage and trigger inflammation

University of Virginia School of Medicine - 05-Mar-2024

The discovery may improve inflammation treatment and anti-ageing interventions

Regenerative hearing drug shows promise in early clinical trials

University College London (UCL) - 05-Mar-2024

Drug LY3056480 didn't fix hearing completely but 45% participants showed better results

RYSE invests $50 million in digital diagnostics startup

pharmaphorum - 05-Mar-2024

Braingaze to develop apps for ADHD, autism and alzheimer's using eye-tracking technology

Argentine scientists explore young blood's anti-ageing effects in rats

Live Forever Club - 04-Mar-2024

The old rats that got young blood lived longer and looked healthier

Senolytic drugs offered mixed clues about their potential impact on ageing

Fight Aging! - 04-Mar-2024

While modifying immune cell populations, the drugs also increased ageing biomarkers

Marcuard Heritage, GenTwo and Maximon offers access to longevity assets for investors

Maximon - 04-Mar-2024

Accessible only for some: minimum of US$10,000 to invest in longevity breakthroughs

Kenai secures $82m to advance cell therapy for Parkinson's disease

Longevity Technology - 01-Mar-2024

iPSC-based therapy set for phase 1 trials to replace lost neurons and modify disease course

Novel approach effectively silences cholesterol genes in mice for a year

News Medical - 01-Mar-2024

This could lead to long-lasting cholesterol treatments without genetic damages

South Korea has the world's fewest babies per woman, and the number keeps dropping

The Guardian - 28-Feb-2024

This is despite spending billions to encourage families to have more children

Invisible stem cells treat disease without triggering immune response

Nature - 28-Feb-2024

Genetically-modified stem cells avoid immune rejection, paving way for universal therapies for everyone

PulseSight unveils minimally invasive gene therapies for eye diseases

Inside Precision Medicine - 28-Feb-2024

Non-viral approach promises long-lasting treatment for AMD patients

Denali secures $500m to develop neurodegenerative disease treatments

Longevity Technology - 28-Feb-2024

Investment fuels its blood-brain barrier-crossing tech for better drug delivery

Yuva Bio secures $7.5M for topical skin and hair treatment targeting mitochondrial dysfunction

Longevity Technology - 26-Feb-2024

Its Y100 technology combats hair loss and potentially other age-related issues

Antibiotics for blindness: Gut bacteria linked to inherited eye diseases

Independent - 26-Feb-2024

CRB1 gene mutation weakens gut barrier, allowing bacteria to invade eyes

The remaining lifespan of old mice, equivalent to a human age of 77 years, doubled

Live Forever Club - 25-Feb-2024

Therapy used OSKM genes to potentially extend lifespan and reverse ageing signs

A protein called APOB, key to blood fat control, could influence your lifespan

Live Forever Club - 25-Feb-2024

Lowering APOB could potentially delay age-related diseases like Alzheimer's

COVID-19 and inequality cast a long shadow on UK life expectancy

The Health Foundation - 23-Feb-2024

Experts calling for action to improve basic needs and address inequalities

Telomere-based interventions offer promising avenues for combating ageing

Live Forever Club - 23-Feb-2024

Telomere research is in its early stages, with much to be discovered

Diabetic monkeys regain insulin independence after transplant of unique insulin cells

Live Forever Club - 23-Feb-2024

This could lead to a safer and better treatment for type 1 diabetes.

Researchers discovered eight things you can do to potentially live longer

Live Forever Club - 23-Feb-2024

Study highlights the power we have to improve our longevity through everyday choices.

A new way to understand ageing by looking at how DNA is organized in our cells

Live Forever Club - 21-Feb-2024

The approach may lead to earlier disease detection & better treatments

Gut bacteria and blood molecules offer clues to why grip strength weakens with age

Live Forever Club - 21-Feb-2024

Research opens doors for future interventions to prevent muscle loss

MMI's surgical robot gears up for global rollout with $110M boost

FierceBiotech - 21-Feb-2024

Symani's wristed instruments bring steady hands and big ambitions to microsurgery

Red light exposure may lower blood sugar levels after meals

Independent - 21-Feb-2024

It reduced blood sugar spikes and overall levels in healthy individuals

Tagomics secures 6.7M euros to revolutionize disease diagnosis with multiomics

Longevity Technology - 21-Feb-2024

Unlocking a new era of comprehensive disease insights and treatment strategies

Tailoring stem cell fate to promote nerve growth and healing

News Medical - 20-Feb-2024

Hydrogels mimicking cellular niche could revolutionize the treatment of brain & spinal injuries

Bioptimus secures $35M to create an AI model for deep biological understanding

Longevity Technology - 20-Feb-2024

This powerful AI could transform how we approach disease research

Fasting-mimicking diet reduces disease risk and slows biological ageing in humans

Medical Xpress - 20-Feb-2024

Fasting improved health markers like insulin resistance and liver fat

London Mayor Sadiq Khan has announced a £2.7M plan to install air filters in 200 schools

Evening Standard - 20-Feb-2024

Plans to extend the program citywide if successful

Lifespan.io speaks to Cyclarity’s CEO for an update on its novel atherosclerosis treatment

Lifespan.io (LEAF) - 19-Feb-2024

The company is developing a drug called UDP-003 to treat the disease

GlycanAge raises $4.2M to develop disease-detecting blood tests using sugar molecules

Longevity Technology - 19-Feb-2024

Company aims to transform healthcare by using cutting-edge sugar-based diagnostics

Lab-grown testicles offer hope for male infertility research

Newsweek - 19-Feb-2024

Artificial testicle technology could lead to a better understanding of male reproduction

Harvard scientists created a tool that predicts how old your cells really are

Harvard University - 16-Feb-2024

This could lead to more accurate testing of anti-ageing interventions

RNA editing therapies for genetic diseases signify medical research progress

Nature - 16-Feb-2024

Unlike editing DNA itself, this new approach makes temporary changes to RNA

New research links DNA damage to incomplete gene transcription in aging

Lifespan.io (LEAF) - 15-Feb-2024

DNA damage accumulated with age worsens gene expression, affecting lifespan-determining pathways

Skincare myths debunked: What products actually work for ageing skin?

Live Forever Club - 14-Feb-2024

To name a few, moisturizers with acidic pH and emollients with active ingredients can help

Spacegoods' mushroom powders to improve mood, energy, and sleep

TechCrunch - 14-Feb-2024

All-natural ingredients to positively impact health and mental wellbeing

Rejuvenate Bio partners with animal company to develop gene therapy for canine osteoarthritis

Biospace - 14-Feb-2024

Single dose injection targets root causes, offering long-term relief & improved quality of life

Drug company BioAge raised $170 million to make new medicines for obesity

Longevity Technology - 13-Feb-2024

Their main drug, azelaprag, is like a pill that mimics the benefits of exercise

Scientists grew tiny heart-like tissues with CVD in a lab dish, using stem cells

University of East London (UEL) - 13-Feb-2024

Research has the potential to revolutionise heart disease treatment in older adults

A new AI tool called Pi helps spot prostate cancer in MRI scans

Independent - 12-Feb-2024

Pi's accuracy might save healthcare costs and free up resources

AI healthcare company Ezra raised $21M to detect diseases early using MRI scans

Longevity Technology - 12-Feb-2024

They plan to offer quick full-body scans for $500 in a few years

Northwestern University launches the Human Longevity Laboratory to fight ageing

Northwestern University - 12-Feb-2024

Researchers will work finding ways to live healthier and longer

Mouse models get a major boost as UK funds research on dementia and ageing

UK Research and Innovation (UKRI) - 12-Feb-2024

This collaboration aims to unlock the secrets of ageing and develop new therapies

Daily choices like exercise, diet, and even how you breathe affect your mitochondria

Live Forever Club - 09-Feb-2024

Making small changes to your lifestyle can have a significant impact on health

Researchers explore the potential of sound waves for anti-ageing

Lifespan.io (LEAF) - 09-Feb-2024

Originally used to fight cancer, sound waves surprisingly revive old cells

Neurona gets $120 million to develop cell therapies for brain disorders

Longevity Technology - 09-Feb-2024

Their treatment uses implanted cells to calm brain activity and repair damaged networks

New questions emerge about where and how to use brain tech safely and fairly

Nuffield Council on Bioethics - 08-Feb-2024

The tech expands beyond medicine, demanding new oversight

New headband backed by $12M uses electricity to improve sleep and memory

Longevity Technology - 08-Feb-2024

Early studies look promising, and the company plans to launch its product soon

A microfluidic device removes potentially tumour-causing cells

Massachusetts Institute of Technology (MIT) - 07-Feb-2024

This low-cost, scalable device could revolutionise spinal cord injuries treatment

Some gut viruses may help you deal with stress by fighting harmful bacteria

The Guardian - 06-Feb-2024

Under stress, the composition of gut viruses and bacteria changed in mice

Fractyl raised $110 million to develop treatments for obesity and diabetes

Longevity Technology - 05-Feb-2024

They picked RJVA-001, a gene therapy, as their first clinical candidate

Scientists found a way to make old cells young again in a lab

Live Forever Club - 04-Feb-2024

They used special proteins to erase "marks" on DNA that build up with age

Mice who sipped green tea all their lives lived longer and stayed healthier

Live Forever Club - 04-Feb-2024

Green tea improved gut health and boosted the immune system in mice

Eating fermented foods like kimchi or yogurt might make you think clearer

Medical News Today - 02-Feb-2024

Adding fermented foods to your diet is a safe way to support your gut

Scientists made hair grow faster by supercharging a natural cell cleanup process

Lifespan.io (LEAF) - 02-Feb-2024

They used a drug called rapamycin in mice to boost the cell cleaning (autophagy)

Hold on Europe! Cleaning up the polluted air later could mean thousands deaths sooner

The Guardian - 02-Feb-2024

Eastern Europe already breathes dirtier air, and the delay would hit them the hardest

Space travel throws a curveball at astronauts' guts, challenging their health

Earth.com - 02-Feb-2024

Understanding the adaptation is crucial for protecting them on long missions

Optispan investigates proactive healthcare to increase healthy lifespan

Longevity Technology - 01-Feb-2024

Company aims to shift medicine's focus from illness treatment to proactive health optimization

Dresden merges recombinases & DNA-binding domains for tailored gene editing

Medical Xpress - 31-Jan-2024

The research offers safer and more precise ways to treat genetic disorders

CardioSignal raised $10 million to improve their heart disease detection app

Longevity Technology - 31-Jan-2024

It is already used in 15 countries to detect atrial fibrillation and heart failure

A CRISPR gene editing technique has cured hereditary angioedema in a single-dose

New Scientist - 31-Jan-2024

It demonstrated a remarkable cure rate, rather than merely offering a treatment

US National Academy of Medicine launches longevity Catalyst Awards

Live Forever Club - 30-Jan-2024

Open to: Individuals, teams, professionals, and anyone with an innovative idea

Scottish company Carcinotech receives funding to make 3D printed mini-tumors

3D Printing Industry - 30-Jan-2024

This £4.2M boost will help them offer this tech more widely in Europe and US

Anti-inflammatory benefits: fasting found to reduce risk of many diseases

University of Cambridge - 30-Jan-2024

Calorie restriction silences the NLRP3 inflammasome, a key driver of inflammation

A new test developed by UC Berkeley researchers claims to predict biological age

GlobeNewswire - 30-Jan-2024

The test involves taking a cheek swab and getting a personalised report

Different organs, like your heart and lungs, can age at different speeds

Live Forever Club - 28-Jan-2024

This means you might need to focus on specific areas of your health to stay spry

Having too much iron in your body can damage organs like lungs and kidneys

Live Forever Club - 28-Jan-2024

This could impact how much iron we get from food or supplements

Scientists found a "nose and gut trick" that could help us live longer

Live Forever Club - 28-Jan-2024

It helped mice live longer, look healthier, and have sharper minds

AI and quantum computing join forces to crack the code of life

EurekAlert! - 26-Jan-2024

This "physics-guided AI" approach promises deeper insights than current methods

UK life expectancy figures expose geographical inequalities

Evening Standard - 26-Jan-2024

Pandemic takes toll, rural and deprived areas see biggest life expectancy drops

New immune cells can recognise and eliminate a specific protein on ageing cells

Live Forever Club - 25-Jan-2024

In mice, this therapy was shown to reduce the number of senescent cells

DNA Nanobots folds its way to funding for disease-targeting drug delivery

Business Wire - 24-Jan-2024

Tiny robots made of DNA can now deliver your medicine straight to the cells

Vesper Bio got almost $1M to develop a new medicine for Parkinson's disease

Longevity Technology - 24-Jan-2024

Vesper's main drug, called VES001, is a pill that can reach the brain directly

The Hevolution Foundation's report proposes a radical shift in healthcare

Live Forever Club - 23-Jan-2024

Report suggests that our focus needs to move from lifespan to healthspan

Sano Genetics, a precision medicine research software company, raised $11.4M

PharmiWeb.com - 23-Jan-2024

Sano's software pinpoints the perfect treatment match for each patient

For every year you spend in school, your life gets 2% longer!

The Guardian - 23-Jan-2024

Skipping classes may be as harmful for your health as smoking

Thousands of young lives are cut short each year by heart disease in England

Sky News - 22-Jan-2024

Death rate reached 80 per 100,000 people in 2022, the highest since 2011

Proteomic Aging Clock (PAC) analyses blood proteins to estimate biological age

Live Forever Club - 21-Jan-2024

PAC could personalise healthcare and guide development of anti-ageing therapies

Turns out, women have a secret weapon in the longevity game: their DNA!

Live Forever Club - 21-Jan-2024

Women have an advantage in longevity genes, especially those related to immunity

Downsizing wine glasses reduces consumption by 7.6%, study finds

BBC - 19-Jan-2024

Portion control solution to curb your overall alcohol intake

Simple at-home fingerprick test reveals thousands of health insights

Stanford University School of Medicine - 19-Jan-2024

Reading metabolic and immune responses, blood test paves way for early diagnosis & personalized medicine

A new method called FAST studies cellular ageing in cultured cells

Live Forever Club - 18-Jan-2024

FAST is precise and works with different cell types and microscopes

Once helpful immune alarm bells, inflammasomes now fuel chronic diseases

Live Forever Club - 18-Jan-2024

Researchers are developing new treatments to turn down the inflammatory response

Reservoir Neuroscience secures $4M to rejuvenate the aging brain

KIZOO Technology Ventures - 18-Jan-2024

New therapies combat age-related brain diseases by restoring blood vessel heath

Global longevity gap narrows as men catching up with women's longer lifespans

New Scientist - 17-Jan-2024

Advances in healthcare and lifestyle changes bridge the gender gap in life expectancy

L'Oréal and Nestlé invest $66M in Timeline's Mitopure technology

Longevity Technology - 17-Jan-2024

Company plans to bring their revolutionary Mitopure technology to the world

Facial, tongue, and retinal images can now reveal your biological age

Live Forever Club - 11-Jan-2024

AgeDiff could be a new way to predict disease risk and personalise healthcare

Halia Therapeutics' NLRP3 inhibitor shows promise in tackling chronic inflammation

Longevity Technology - 11-Jan-2024

Shown promising results in preclinical studies and early clinical trials

CRISPR-edited stem cells promise rejection-free regenerative therapies

University of Arizona - 11-Jan-2024

Genetically modified stem cells bypass immune rejection, paving way for universal therapies

Skin microbiome diversity is linked to wrinkles and hydration

University of California, San Diego (UCSD) - 11-Jan-2024

The findings pave the way for personalised skincare approaches

Eating less activates the gene OXR1 which controls brain ageing and lifespan

Buck Institute - 11-Jan-2024

Research sheds light on the benefits of calorie restriction

COVID stole years from UK lives, pushing clocks back ten years on life expectancy

The Guardian - 11-Jan-2024

Experts warn that the pandemic's impact goes beyond just a few lost years

Vegan diet may slow ageing clocks on a cellular level in 8 weeks

Live Forever Club - 10-Jan-2024

Those who ate a vegan diet had lower levels of epigenetic age acceleration

Gallant Therapeutics snags $15M to develop stem cell therapies for pets

Biospace - 08-Jan-2024

Focused on regenerative treatments for feline gingivitis, canine arthritis, and more

Ageing may be driven by disruptions in electrical signals between cells

Live Forever Club - 05-Jan-2024

Bioelectric signals could even promote tissue regeneration

Cambridge scientists are making significant strides in understanding ageing

Cambridge Independent - 05-Jan-2024

Promising leads for potential anti-ageing interventions in the next decade

Epigenetic remodelling startup 'Moonwalks' out with $57M to develop targeted therapies

Longevity Technology - 04-Jan-2024

This, they claim, is safer and more precise than traditional gene editing methods

Life's curveballs can fast-forward your biological clock and make you look older

National Institute on Aging (NIA) - 04-Jan-2024

These age-jumps, measured by DNA changes, can actually reverse once the stressor fades

Some drugs may dampen the benefits of exercise, while others amplify them

Live Forever Club - 01-Jan-2024

Complex interactions with drugs like Rapamycin, Metformin, and SGLT2 inhibitors

Activating SIRT6, a DNA repair protein, reduces damage in ageing cells

Live Forever Club - 01-Jan-2024

SIRT6 activation may be a potential therapeutic target for osteoarthritis

A cellular protein called HKDC1 tidies up mitochondria and lysosomes

Interesting Engineering - 01-Jan-2024

This discovery paves the way for potential anti-ageing therapies

Ageing may not be just wear and tear, but a programmed continuation of development

Live Forever Club - 31-Dec-2023

Methylation patterns, measured by epigenetic clocks, offer novel insights

Josh Mitteldorf's new view of ageing shows body's fight for life

Live Forever Club - 31-Dec-2023

Study reveals two sides to ageing: a programmed decline and a desperate defense

Our sleep cycles and gut bacteria influence the brain's protective barrier

Live Forever Club - 30-Dec-2023

Interplay between these systems suggests potential for targeted interventions

El País interviews Altos Labs’ principal investigator Pura Muñoz Cánoves

El País - 27-Dec-2023

Altos labs with a $3-billion budget pave the way for reversing aging and extending healthy lifespan

LEV Foundation announces plan for second Robust Mouse Rejuvenation study (RMR2)

Live Forever Club - 22-Dec-2023

Will look at combinations of partial cellular reprogramming, mesenchymal stem cells, serum albumin and deuterated fatty acids

Fauna Bio hunts for novel obesity drugs in $494m Lilly partnership

Longevity Technology - 21-Dec-2023

Fauna's AI platform explores animal data to unlock breakthroughs in weight management

MeiraGTx at the forefront of gene therapy for cancer, obesity, and vision loss

Evening Standard - 21-Dec-2023

London biotech promises revolutionary therapies by replacing faulty genes & flipping gene switches

Cambridge researchers continuously explore novel approaches to improve healthspan

University of Cambridge - 20-Dec-2023

Quest for people to live healthily for as long as possible will inevitably result in longer lives

Ageing eyes face a double whammy of senescent cells and weakened defenses

Live Forever Club - 19-Dec-2023

Senolytic intervention helps to repair the protective barrier of the eyes

Fisetin in berries and apples could shield your heart in later years

Live Forever Club - 19-Dec-2023

Supplementation reduced the buildup of senescent cells in the arteries of aged mice

Your daily choices, whether at the gym or in your meals, can redefine your age

Live Forever Club - 15-Dec-2023

Cellular senescence can be significantly mitigated by a holistic lifestyle

Is your heart older than you are? The lifestyle habits ticking away at your time

Live Forever Club - 15-Dec-2023

Complex interplay of genetics and lifestyle in influencing heart health

Twin Health raises $50m to help you conquer chronic metabolic diseases

Longevity Technology - 15-Dec-2023

Silicon Valley startup uses personalized data and AI twin to reverse type 2 diabetes and obesity

Irina Conboy launches Generation Lab, using noise-detecting cytosines to measure biological age

Live Forever Club - 14-Dec-2023

The method measures increased fluctuations in methylation levels called "noise"

MitoRx's $5M funding sets the stage for treating muscle and lung diseases

Longevity Technology - 14-Dec-2023

Company's drug targets the root cause of diseases like Duchenne and COPD

$20.6 million fuels Vandria's mission to conquer ageing and chronic diseases

Longevity Technology - 14-Dec-2023

Mitophagy-boosting drug candidate VNA-318 preps for clinical trials

Estée Lauder is launching a new cream to focus on anti-ageing

Business Wire - 14-Dec-2023

It's based on sirtuins research and claims to provide visible results in 14 days

Mice regain vision through partial cellular reprogramming of retinal cells

Lifespan.io (LEAF) - 13-Dec-2023

While age ultimately caught up, study demonstrates potential of the novel treatment

Three UK non-profit organisations take International Longevity Alliance federated membership to over 50

Live Forever Club - 12-Dec-2023

BSRA, BGRF and ATLAS join the global campaign group promoting the advancement of healthy longevity for all

Antioxidants and seasickness meds show promise in extending life in male mice

Live Forever Club - 11-Dec-2023

The gender-specific effects observed underscore the complexity of ageing

Europe's age wave: challenges & opportunities for a longer, healthier future

International Longevity Centre UK - 11-Dec-2023

From prevention to participation, a roadmap for healthier, happier, and more productive lives

New ultrasonic 3D printing tech mends broken hearts and bones without surgery

Singularity Hub - 10-Dec-2023

Sound waves and a special ink to print custom implants and deliver drugs directly to injured tissues

Fountain life acquires lifeOmic to deliver healthcare anywhere, anytime

Longevity Technology - 10-Dec-2023

AI-powered data platform empowers early disease detection and proactive care at home

$200 billion bet on drug that could make us all live better, longer

Libraries for the Future - 09-Dec-2023

Clinical trials for the ageing drug could potentially be completed in 3-6 years

Our genes push for early babies, but at the cost of living shorter lives

University of Michigan - 08-Dec-2023

But don't stress, modern factors like healthcare and lifestyle have a bigger impact than genes

A revolutionary blood test that can estimate your organs' biological age

BBC - 07-Dec-2023

Test could help in the early detection of disease and prevention strategies

SIRT2 overexpression does not significantly impact lifespan in mice

Live Forever Club - 05-Dec-2023

Study suggests a more nuanced role of this protein in the ageing

The reign of dinosaurs may have shaped how humans and other mammals age

Live Forever Club - 05-Dec-2023

Dinosaur-era pressures may have led to the loss of longevity genes

Biolexis Therapeutics secured $10M for the development of metabolic drugs

Longevity Technology - 05-Dec-2023

The drugs target obesity, diabetes, and potentially, human longevity

Mechanical reprogramming enhances fibroblast function for skin rejuvenation

Lifespan.io (LEAF) - 04-Dec-2023

The method enhances their abilities and promotes wound healing in aged skin

ARCUS gene editing technology effectively eliminates mutant mitochondrial DNA

Biospace - 04-Dec-2023

Potential therapeutic approach for mitochondrial and other genetic diseases

Green neighborhoods linked to longer lives and slower ageing

The Guardian - 01-Dec-2023

Every 5% increase in green space adds 1% younger cells to your body

Forsyth's breakthrough in tissue regeneration for root canal alternatives

Forsyth Institute - 01-Dec-2023

Natural, innovative approach effectively revitalizes dental pulp and slows infections

XPRIZE Launches a $101 Million Healthspan Competition

Live Forever Club - 29-Nov-2023

10 years of functional age-reversal in 65-80 year olds within the next 7 years... bring it on!!!

Blue zones: new data casts doubt on longevity hotspots

Slate - 29-Nov-2023

A Brit's skeptical take on Blue Zones and the search for eternal life

Gene regulation shifts with age, especially in species with shorter lifespans

Live Forever Club - 28-Nov-2023

CpG density may play a role in moderating the epigenetic drift

Cancer Research UK manifesto to avoid 20,000 cancer deaths

BBC - 27-Nov-2023

Bold plan needed to fix NHS, boost research, and end preventable deaths

Canadians' life expectancy falls in 2022 for the third year in a row

The Canadian Press - 27-Nov-2023

COVID-19 takes a toll, seniors hit hardest, and Atlantic Canada sees highest jump

UK study reveals path to healthier, longer life through dietary choices

Live Forever Club - 24-Nov-2023

Embracing healthier dietary choices can extent life expectancy to some degree

LensAge index: A new method to estimate biological age using lens photographs

Live Forever Club - 23-Nov-2023

Offers a precise measure of body's biological state and its link to mortality

Vivodyne pioneers drug development with lab-grown organs with $38M funding

Longevity Technology - 22-Nov-2023

Offers over 20 innovative organ models for realistic testing and collaborating

A fatty acid in beef and milk could be used to treat cancer

New Scientist - 22-Nov-2023

The acid eliminates tumours by activating immune cells to combat cancerous cells

Frieda Health raised EUR 2.5 million to advance their menopause platform

Live Forever Club - 20-Nov-2023

A step towards empowering women for better health and quality of life

C. elegans: A tiny worm that can help scientists understand how ageing works

Live Forever Club - 20-Nov-2023

The research could lead to new ways to slow down ageing in humans

People in the north of England are living in poorer health and dying younger

The Guardian - 19-Nov-2023

New report exposes shocking inequalities in health, wealth, & opportunity facing older people in England

Immune Resilience: a blueprint of your immune system that unveils the secrets of longevity

Big Think - 19-Nov-2023

Science behind your body's ability to live longer, resist infections and survive diseases

UK's approval of casgevy paves the way for gene-edited treatment of blood disorders

BBC - 16-Nov-2023

Casgevy offers hope for patients with sickle cell disease and beta thalassemia

3D printed functional hair follicles from lab-grown human skin

Rensselaer Polytechnic Institute - 15-Nov-2023

A revolutionary step towards regenerative medicine, drug testing, and enhanced skin models

England sets ambitious goal to eliminate cervical cancer by 2040

BBC - 15-Nov-2023

Increased vaccination and improved screening are key to achieving the target

Single-dose gene-editing therapy offers permanent solution to high cholesterol levels

New Scientist - 14-Nov-2023

Early results show promise in eliminating the need for lifelong statins

U.S. men are dying much younger than women, as gender gap for death widens

New Scientist - 13-Nov-2023

COVID-19, drug and alcohol abuse, & suicide fuel a 6-year life expectancy disparity

Variations in iron metabolism impact biological ageing at an epigenetic level

Live Forever Club - 11-Nov-2023

Offering insights into ageing processes and potential therapeutic targets

Evolved.Bio pioneers a scaffold-free method to regenerate muscle tissue

Phys.org - 10-Nov-2023

Offering hope for individuals with significant muscle damage

Forward therapeutics secures $50m to develop next-gen small molecule immune therapies

Longevity Technology - 09-Nov-2023

Company's pipeline targets inflammation, promote healing, and restore quality of life

Bit.bio reveals early pipeline of regenerative medicine candidates

Endpoints News - 08-Nov-2023

Lead program bbHEP01 targets severe acute liver failure, with phase I trial planned for 2025

L-Nutra secures $47M investment to develop an innovative diet plan

Longevity Technology - 08-Nov-2023

Company's fasting mimicking technology could revolutionise ageing

MHRA has approved Mounjaro, a diabetes drug that promotes weight loss

GOV.UK - 08-Nov-2023

The drug works by regulating appetite and reducing cravings

SRW and Insilico partner to develop AI-powered nutraceuticals

Longevity Technology - 08-Nov-2023

Using AI to screen natural compounds and create novel longevity products

New AI tool ENABL Age provides personalised insights into healthy ageing

Live Forever Club - 07-Nov-2023

A stepping stone towards personalized anti-ageing interventions

Senescent cell weakness exploited by new anti-aging therapy

Singularity Hub - 07-Nov-2023

FDA-approved drug kills zombie cells and improves organ function in elderly mice

Turn Biotechnologies delivers mRNA to skin layers without affecting other organs

CISION PR Newswire - 07-Nov-2023

Opens avenues for novel drug therapies previously deemed impossible

New drug offers hope for thousands of women at risk of breast cancer

BBC - 06-Nov-2023

Anastrozole could prevent risk of disease by 50% among eligible women in England

Alcohol linked to changes in DNA that could lead to earlier ageing

Live Forever Club - 02-Nov-2023

Effects of alcohol on DNA ageing are not limited to specific demographics

Senolytics may rejuvenate heart cells and prevent age-related heart disease

Live Forever Club - 02-Nov-2023

Drugs have the potential to revolutionise the way we treat age-related diseases

Scientists have created a special type of melanin that can heal skin wounds

Northwestern University - 02-Nov-2023

Also shields skin from sun damage, environmental toxins, and radiation exposure

Longevity funding innovation prize: shaping the future of longevity research

Live Forever Club - 01-Nov-2023

A $20,000 prize for innovative approaches to increase longevity sector funding

Aqtual's blood test could help doctors choose the right treatment for you

Longevity Technology - 01-Nov-2023

Company's "cell-free DNA platform" can detect unexplored cell-free DNA fragments

Humanity Inc.'s AI-powered health app helps you live longer and healthier

Master Investor - 01-Nov-2023

The app helps users boost their energy levels and feel more alive

Gate Bioscience, backed by a $60M funding, introduces new class of small molecule drugs

CISION PR Newswire - 01-Nov-2023

The novel drugs called molecular gates eliminate disease-causing proteins

Collagen peptides improve skin wrinkles, hydration, elasticity, and whitening

Live Forever Club - 30-Oct-2023

Supplementation enhanced fibroblast activity and ECM synthesis

Sky Labs secures $15M for 24/7 monitoring device with holistic insights

Longevity Technology - 30-Oct-2023

Ring-type blood pressure monitor to revolutionise hypertension management

Your biological clock may tell you more about your memory than your age

Stony Brook University - 30-Oct-2023

People with a faster biological age tend to have poorer memory

New mice with human-like telomeres could help us fight ageing and cancer

The Jerusalem Post - 30-Oct-2023

Model could be used to study the role of telomere length in several diseases

Nanomedicine company NaNotics receives investment from LifeSpan Vision Ventures

LifeSpan Vision Ventures - 30-Oct-2023

Nanotech's nanoparticles could extend healthspan for everyone

New blood test can use AI to estimate your age and health risks

Live Forever Club - 29-Oct-2023

New machine learning model estimates biological age with unprecedented accuracy

Rishi Sunak invests £100M in AI to accelerate research for cancer and dementia

Independent - 29-Oct-2023

Michelle Donelan praises the AI investment, stating it will transform healthcare

A new gene therapy treatment has helped deaf children hear for the first time

MIT Technology Review - 27-Oct-2023

Treatment delivers a working copy of a missing gene to the inner ear

New DNA test gives dog owners a peek inside their pet's health

Live Forever Club - 26-Oct-2023

MyDogDNAge® measures a dog's biological age and health risks

Regular jogging or running could help to keep cells younger and healthier

Live Forever Club - 26-Oct-2023

Jogging or running for at least 75 minutes per week linked to longer telomeres

Health-care costs are no longer taking over the economy. But why?

The Economist - 26-Oct-2023

Factors include productivity gains, technology, and slower economy growth

Scientists discovered that fish in Apache lake live exceptionally long lives

Live Forever Club - 25-Oct-2023

Some fish species in the lake, like bigmouth buffalo, can live over 100 years

UK air pollution regulations are saving lives, but not protecting ecosystems

University College London (UCL) - 25-Oct-2023

Existing regulations are not enough to protect sensitive habitats from ammonia

Healthy ageing: addressing the global challenge of quality life years

Live Forever Club - 24-Oct-2023

Extending healthy years, not just lifespan, as populations age

Scientists have developed a revolutionary biological ageing clock- the OMICm Age

Live Forever Club - 24-Oct-2023

Advanced biological ageing clock provides a precise evaluation of health & ageing

Endogena Therapeutics unlocks regenerative potential with FDA-approved AMD treatment

Endogena Therapeutics - 24-Oct-2023

Company's EA 2351 paves the way for potential vision restoration in patients

LyGenesis raises $19 million to grow organs inside lymph nodes

Juvenescence - 24-Oct-2023

Company's innovative approach could revolutionise organ transplantation

Frontier Bio's lab-grown blood vessel tech revolutionizes medical device testing

3DPrint.com - 24-Oct-2023

Promises a future without animal testing and the need for organ donors

Unravelling the complexities of aging: A comprehensive database of aging factors

Live Forever Club - 23-Oct-2023

A deep dive into the AgingReG curated database of aging regulatory relationships in humans

Northern Ireland's precision medicine sector receives £7.5 million boost

Belfast Telegraph - 23-Oct-2023

Government funding to fuel innovation and growth in the life science sector.

Mapping eye proteins reveals secrets of ageing and Parkinson's

SciTechDaily - 22-Oct-2023

Researchers map thousands of eye proteins, shedding light on ageing mechanisms

Mayo clinic and Oxford nanopore partner up to revolutionise precision medicine

Business Wire - 19-Oct-2023

Unlocking the secrets of cancer and genetic diseases with nanopore sequencing

UC Davis researchers uncover a gene linked to longevity in Golden Retrievers

UC Davis - 19-Oct-2023

HER4 gene types added approximately 2 years to their lifespan

Personalised cell therapy for Parkinson's receives FDA fast track designation

Biospace - 19-Oct-2023

Aspen Neuroscience's ANPD001 aims to replace lost neurons and improve motor function

Gut microbes linked to the risk of Parkinson’s and Alzheimer’s diseases

University of Massachusetts Lowell (UMass Lowell) - 19-Oct-2023

Gut-brain connection opens doors for early detection and treatment of brain diseases

Gero raises $6M to hack the ageing code and combat age-related diseases

Longevity Technology - 18-Oct-2023

Company's quest to decode ageing and develop novel therapies gains momentum

Arctop raises $10 million for brain decoding software to boost human potential

Longevity Technology - 17-Oct-2023

Platform decodes brain signals, enabling thousands of applications

Scientists find a new way to replace lost neurons after stroke

Kyushu University - 17-Oct-2023

Microglia conversion sparks a paradigm shift in stroke treatment

Gut bacteria linked to Alzheimer's disease in groundbreaking study

King's College London - 17-Oct-2023

Research findings may lead to new treatments for the most common cause of dementia

Insights from the 4th longevity investors conference - future health & longevity

Live Forever Club - 16-Oct-2023

The event's success fuels optimism for future longevity awareness events

French artificial heart maker CARMAT receives a financial boost

Longevity Technology - 16-Oct-2023

Aims to reach an annual production capacity of 500 artificial hearts

Eating less, living longer: the positive effects of calorie restriction

International Institute on Ageing (INIA) - 16-Oct-2023

Modest calorie reduction can activate genes for healthy ageing

Dimension Inx's CMFlex 3D printing brings a new way to repair bones

3D Printing Industry - 16-Oct-2023

Structure promotes bone healing in oral and maxillofacial surgeries

AI in healthcare: King's fund panel calls for governance and structure

Digital Health - 16-Oct-2023

Experts warn of the need for guidelines & oversight to ensure safe use of AI in healthcare

Beyond CRISPR: Fanzors, a new era of programmable DNA editing tools

Massachusetts Institute of Technology (MIT) - 13-Oct-2023

Scientists discover a vast array of RNA-guided enzymes in diverse organisms

The stress of renting is taking a toll on our physical and mental health

BBC - 12-Oct-2023

Insecurity and rising cost of private renting accelerate biological ageing

New brain atlas reveals thousands of previously unknown cell types

New Scientist - 12-Oct-2023

Could lead to new insights into neurological and mental health conditions

CT scans of thymus may reveal immunological ageing

Medical Xpress - 12-Oct-2023

Researchers find link between thymus appearance and lifestyle factors, immune cell regeneration

UK biotech startup Astronautx raises $61M to tackle neurodegenerative diseases

Longevity Technology - 11-Oct-2023

Aims for Alzheimer's drugs that target brain's predominant cells, astrocytes

Genetic profiling conducted by the mexico city prospective study highlights the value of genetic studies in diverse populations

Oxford Population Health - 11-Oct-2023

Study reveals new insights into obesity, diabetes, and genetic diversity

Largest centenarian blood study identifies key factors for long life

Independent - 10-Oct-2023

Lower levels of glucose, creatinine, and uric acid linked to increased longevity

Why some people find it easier to be a vegetarian than others

New Scientist - 04-Oct-2023

Three gene variants more prevalent in vegetarians, impacting dietary choices

ExcepGen secures $14M seed funding to develop new mRNA technology

Longevity Technology - 04-Oct-2023

Technology could make mRNA vaccines and therapeutics more effective and safer

Microsure raises $40M to revolutionise microsurgery with MUSA-3 robot

MassDevice - 04-Oct-2023

MUSA-3, a next-gen microsurgical robot, boosts surgical precision and versatility

Bioprinted skin is a new way to heal wounds faster, with less scarring

New Atlas - 04-Oct-2023

Scientists craft lifelike skin to aid chronic wound and burn care

Scientists 3D print brain tissue, paving the way for brain disorder treatments

Interesting Engineering - 04-Oct-2023

A personalised approach to healing the brain and restoring lost function

A&E screening could detect thousands of undiagnosed diabetes cases

Sky News - 04-Oct-2023

Early diagnosis of type 2 diabetes with simple blood test can help you avoid serious complications

Mogrify boosts series A to $46m to accelerate cellular reprogramming therapies

Longevity Technology - 03-Oct-2023

Technology could revolutionise the treatment of degenerative diseases

Early diagnosis and treatment of type 2 diabetes can add years to your life

University of Cambridge - 03-Oct-2023

Diagnosis at 30 may cut 14 years off life, but early treatment can extend it

AI holds the promise of longer lives, shorter workweeks, and economic growth

CNBC - 03-Oct-2023

Jpmorgan CEO sees AI transforming healthcare, workforce, and global economy

Automata raises $40M to make science labs more efficient and productive

TechCrunch - 03-Oct-2023

Company's LINQ platform streamlines drug development for scientists

Hair cloning: A new hope for reversing male pattern baldness

The Guardian - 01-Oct-2023

The treatment banks youthful hair follicles, clones the cells, and regrows hair

Buck Institute and Phenome Health team up to advance scientific wellness

Buck Institute - 27-Sep-2023

Collaboration of data and discovery to extend healthspan for everyone

Rice researchers awarded $45M to develop cancer implant that could save millions

Rice University - 26-Sep-2023

Implant continuously monitors cancer and adjusts immunotherapy dose in real time

Treatment with stem cells may help slow down multiple sclerosis

Independent - 26-Sep-2023

Offers hope for aHSCT as the future standard of care for 130,000 UK MS patients

Lifespan.io reports back from Aging Research and Drug Discovery Meeting (ARDD 2023)

Lifespan.io (LEAF) - 26-Sep-2023

Key points from Arkadi Mazin's summary of 5 days of talks by geroscientists and biotech leaders

People will live shorter lives due to the rising cost of living in the UK

The Guardian - 25-Sep-2023

The poorest will face the hardest hit, with deaths rising four times faster

New venture capital firm age1 aims to extend healthy lifespan

Longevity Technology - 22-Sep-2023

Investing in the next generation of longevity biotech companies

The Chan Zuckerberg Initiative to launch AI supercomputer for decoding biology

GEN News - 22-Sep-2023

New AI technologies promise to accelerate scientific discoveries and cure diseases by the end of the century

New AI tool predicts genetic mutations that could cause disease

The Guardian - 19-Sep-2023

AlphaMissense is a game-changer in genetic research for human health

Broken string secures $15m to make cell and gene therapy safer, more accessible

Longevity Technology - 19-Sep-2023

Company's INDUCE-seq platform could revolutionise cell & gene therapy efficiency

Sonera secures $11M investment for revolutionary neural sensing chip technology

Longevity Technology - 14-Sep-2023

Technology can successfully measure muscle activity, brain waves, and more

New peptide-based technology selectively erases ageing cells

Ulsan National Institute of Science and Technology (UNIST) - 14-Sep-2023

Mitochondria targeting could lead to new treatments for age-related diseases

NHS still reliant on paper records, despite progress towards electronic systems

The BMJ - 13-Sep-2023

75% of trusts still use paper, hindering patient safety and efficiency

Actio Biosciences secures $55M to develop drugs using precision medicine

Business Wire - 12-Sep-2023

Lead program targets TRPV4, an ion channel that is involved in several diseases

Humacyte's bioengineered tissue outperforms synthetic grafts

FierceBiotech - 12-Sep-2023

Human acellular vessel showed better results in vascular trauma repair

Transplanting patients' own cells holds promise in repairing damaged lungs

Independent - 11-Sep-2023

Small clinical trial shows treatment can improve breathing and quality of life

ProMIS secures $20.4M to accelerate Alzheimer's antibody development

Longevity Technology - 11-Sep-2023

Lead antibody shows promising preclinical data & is set for clinical development

AI model estimates age from chest X-rays to develop biomarkers for ageing

SciTechDaily - 09-Sep-2023

The model predicts the risk of chronic diseases before they even show up

AI startup Inceptive to use $100M funding for novel medicines

Longevity Technology - 08-Sep-2023

Developing "biological software" for effective and affordable mRNA drug design

Rejuvenation Technologies raises $10.6M to develop anti-ageing therapies

Longevity Technology - 07-Sep-2023

A single dose of mRNA therapy could rewind ageing and extend lifespan

Resistance training: the secret to younger-looking skin and positive mood

Health - 07-Sep-2023

Resistance training can thicken the dermal layer and boost collagen production

Phase I trial shows early promise in clearing senescent cells in Alzheimer's

Wake Forest Baptist Health - 07-Sep-2023

The treatment was well-tolerated with no significant changes in brain function

Embryo model grown without sperm, egg or womb: A breakthrough for ethical research

BBC - 06-Sep-2023

Stem cell-based embryo models could lead to new treatments for infertility

Plant-based diets can slow down ageing and help you live longer

Lifespan.io (LEAF) - 06-Sep-2023

Fresh fruits, vegetables, and legumes reduce the risk of age-related diseases

Urolithin A, a natural compound, reverses age-related decline in immune system

EurekAlert! - 06-Sep-2023

Urolithin A rejuvenated blood stem cells in mice, boosting infection defence

Stem cell therapy gives arthritic gorilla new lease of life

Interesting Engineering - 03-Sep-2023

Liesel the gorilla is now walking again after receiving Stem CellX treatment

Yuvan's E5 therapy receives investment to move into canine trials

Longevity Technology - 31-Aug-2023

Pig plasma therapy could reverse aging in humans

Senolytics have gender-specific effects on ageing in young mice

Lifespan.io (LEAF) - 30-Aug-2023

More research is needed to determine the safety and efficacy of senolytics in humans

New blood test may help in early detection of Parkinson’s disease

Independent - 30-Aug-2023

The test could identify drugs that reverse or slow down DNA damage and disease

NHS partners with barbershops, clubs and mosques to improve heart health

BBC - 29-Aug-2023

Free blood pressure checks to help people identify and manage blood pressure

Rejuve.Bio combines AI with fruit fly genetics to unlock the secrets of long life

Longevity Technology - 24-Aug-2023

Novel approach to identify ageing targets and fight age-related diseases

Naked mole rats' secret to long life could be unlocked for humans

University of Rochester - 23-Aug-2023

Scientists transfer the longevity gene to mice, extending their lifespan by 4.4%

Genesis Therapeutics raised $200M in series B for AI-driven drug discovery

Longevity Technology - 22-Aug-2023

Funds to help AI-discovered drugs enter clinical trials and expand its pipeline

USC-supported startup receives $21m to develop stem cell patch for eye disease

University of Southern California (USC) - 21-Aug-2023

Funding will be used to test the patch in geographic atrophy patients in phase 2b trial

Human cell's memory erased to resemble embryonic stem cells

EurekAlert! - 16-Aug-2023

New reprogramming method addresses epigenetic challenges & sets a standard for cell therapy research

New AI model predicts your true age by looking at your chest

Medical Xpress - 16-Aug-2023

AI-estimated age based on chest radiographs could be a biomarker of ageing and disease

PF4: the tiny protein that could boost your brain power, no matter your age

University of California, San Francisco (UCSF) - 16-Aug-2023

PF4 from platelets enhanced learning and memory in both young and old mice

Stem cell-derived organoids secrete enamel proteins that could repair or replace lost teeth entirely

University of Washington (UW) - 14-Aug-2023

A breakthrough approach to make enamel by mirroring gene pathways in natural tooth formation

Human heart on a microchip: A revolutionary new tool for medical research

Methuselah Foundation - 14-Aug-2023

Organ on a chip may be more successful than mice models in translating science to the clinic

Epigenetic insights: developmental changes in DNA linked to lifespan in mammals

EurekAlert! - 10-Aug-2023

Universal clock based on methylation profiles to accurately predict age in all mammalian species

AI identifies new senolytics that could treat age-related diseases

Lifespan.io (LEAF) - 09-Aug-2023

Three natural compounds identified, paving the way for new treatments

New, publicly available "unknome" database for poorly studied proteins

New Scientist - 08-Aug-2023

Many neglected proteins/genes have essential function, finding out may accelerate future research

Neuralink's brain implant gets $280M in funding, eyes clinical trials

FierceBiotech - 08-Aug-2023

FDA approves Neuralink's brain implant, patients can now sign up for trials

Amber Bio secures $26M funding to advance new gene editing technologies

Longevity Technology - 07-Aug-2023

By editing RNA instead of DNA, the company aims to treat multiple undruggable genetic diseases safely

Signalling pathways in aged cells found to impair the ability to repair and regenerate muscle cells

Independent - 07-Aug-2023

Study results offer insights on future drug discovery for disease related to muscle ageing

Sleep inequality: study finds people in deprived areas have worse sleep

The Guardian - 07-Aug-2023

Study finds strong link between social deprivation, ethnicity and sleep quality

3D scaffolds grow retinal cells to combat macular degeneration

ScienceAlert - 06-Aug-2023

Researchers achieve 150-day retinal cell growth, but biocompatibility uncertain

Voyager's new gene therapy targets amyloid plaques in Alzheimer's disease

FierceBiotech - 04-Aug-2023

New treatment approach could be more effective in lowering the risk of serious side effects

Longevity Technology interviews Lineage's CEO on the role of cell therapy in improving human longevity

Longevity Technology - 03-Aug-2023

Details magic of converting stem cells to any cell type and transplanting them to treat age-related conditions

Eye-opening discovery: a potential non-invasive solution for age-related vision loss

Live Forever Club - 02-Aug-2023

Deglycating enzymes could offer an affordable, effective, and non-invasive treatment for presbyopia

Epiterna receives 10m euros to extend lifespans of pets and people

Sifted - 01-Aug-2023

Planning to test its therapies in dogs next year, with human treatments expected in the near future

Scientists design a rapid and inexpensive method to grow human blood vessels

Pursuit by The University of Melbourne - 01-Aug-2023

Tissue engineered blood vessels might replace bypass surgery to treat heart disease in future

If we can fix the bugs in human software, people could live to be 20,000 years old

Scientific American - 31-Jul-2023

Bill Gifford interviews João Pedro de Magalhães, professor of molecular biogerontology at the University of Birmingham

Experimental vaccine promises to slow down or prevent Alzheimer's in mice

American Heart Association - 30-Jul-2023

Vaccine not only reduced inflammation, but also improved behavior and awareness in mice

Genetics and physical markers reveal that women age faster in their 30s and 50s

New Scientist - 28-Jul-2023

Hormonal changes during pregnancy and menopause may speed up the ageing process

Intermittent fasting may help you lose weight and fight infections

New Scientist - 28-Jul-2023

T cells effectively fight pathogens using energy fuel as ketones, which are typically produced in fasting

COVID-19 continues to take a toll on Japanese life expectancy

Japan Times - 28-Jul-2023

Overall dropped by 0.42 years for men and 0.49 years for women in 2022 - second fall in a row

Vital Bio raised $48m to market its revolutionary blood testing platform

Longevity Technology - 27-Jul-2023

VitalOne reports 50 lab tests in just 20 minutes and improves accessibility for clinicians & patients

Celularity and Versea Ophthalmics to commercialize ophthalmic allografts

Celularity - 27-Jul-2023

Innovative BIOVANCE single- and three-layer products for ocular surface disease treatment & surgical support

Young blood slows down ageing process of older mice

New Scientist - 26-Jul-2023

Infusion of youthful blood increased lifespan by 5% and improved age-related gene alterations

Major illnesses will affect over nine million people in England by 2040

BBC - 25-Jul-2023

Large increases in people with anxiety, depression, chronic pain, and diabetes

Metformin may minimize muscle loss in extended periods of bed rest

Lifespan.io (LEAF) - 24-Jul-2023

Improvements seen in muscle size and collagen deposits in older people with atrophy

Superior killer T-cells hold promise in remission and clearance of cancer

Cardiff University - 24-Jul-2023

Multipronged T-cells recognize multiple target proteins and attack cancer in many ways

Your genes determine your food cravings and eating habits

New Scientist - 22-Jul-2023

Identifying genetic preferences may hold the key to personalized nutrition and healthy eating

System Age epigenetic clock captured different patterns of ageing

Lifespan.io (LEAF) - 21-Jul-2023

Novel method for precise estimation of biological age and disease risks with a single blood sample

SiPhox Health raised $27m to advance at-home medical tests

TechCrunch - 19-Jul-2023

Lab-grade kit that measures 17 biomarkers of health & fitness with a finger-prick blood sample

Causaly raised $60m in Series B to revolutionize biomedical research

Longevity Technology - 17-Jul-2023

AI-powered research platform to accelerate the processes in drug discovery and development

Novel method facilitates single-cell expansion of gene edited stem cells

Lifespan.io (LEAF) - 17-Jul-2023

Its polymer-supplemented culture system enables cell expansion without harmful mutations

Darius Widera warns of rogue stem cell therapy clinics

The Conversation (UK) - 14-Jul-2023

Unregulated clinics worldwide are offering unproven, dangerous treatments, exploiting regulatory loopholes and misleading desperate patients

Chemical cocktail able to reprogram cells to reverse ageing, without the need for gene therapy

Live Forever Club - 13-Jul-2023

David Sinclair and team discovers potential new approach to treat age-related diseases and promote healthy aging

Duo of world leading transhumanists argue for the scientific possibility of physical Immortality in their new book

Live Forever Club - 11-Jul-2023

Recommended by Aubrey de Grey, Ray Kurzweil, George Church, Michio Kaku and many more - they can't all be wrong!

Stem cells may grow dental tissue or an entire human tooth for implant

Drug Discovery News (DDN) - 11-Jul-2023

Lab grown tooth could soon become a reality - provides hope against painful root canal treatments

J&J extends $30m deal with Nanobiotix for global co-development of radioenhancer

FierceBiotech - 10-Jul-2023

NBTXR3 to enhance the effect of immunotherapies; plans for phase 3 trial in head and neck cancer

Gene therapy restores partial red colour vision in total colour blindness patients

New Scientist - 10-Jul-2023

Despite the limited improvement, gene therapy offers hope for future breakthroughs in restoring vision

Camena Bioscience raises $10m in series A for DNA synthesis technology

Longevity Technology - 10-Jul-2023

Highly accurate enzyme-based approach to advance the ability to read, write and manipulate DNA

Videregen seeks $10m funding for clinical trials of regenerated organs and tissues

Longevity Technology - 07-Jul-2023

Ground-breaking technology to advance the development of a bio-engineered thymus & lung disease treatments

Mitochondria-targeted compound prevents and treats metabolic syndrome in mice

Buck Institute - 07-Jul-2023

Selectively inhibits problematic free radicals - potential breakthrough in treatment of chronic diseases & ageing

Automating genetics research: A robotic system for handling C. elegans (with video)

Phys.org - 06-Jul-2023

WormPicker takes on time-consuming tasks including inspection, movement between petri dishes and genetic crossing

England's chief medical officer says vehicle tyre pollution is now a major health risk

The Guardian - 05-Jul-2023

Heavier electric vehicles raise concerns from increased tyre wear pollution despite resolving exhaust emissions

AVEA's seed funding doubles to $5 million - paving the way for growth in longevity supplements

Live Forever Club - 04-Jul-2023

Aims to spread its life-enhancing solutions (including collagen booster) further across the globe

CollPlant gains $10m milestone from AbbVie to develop dermal and soft tissue filler

Longevity Technology - 04-Jul-2023

Recombinant human collagen based fillers help advance the field regenerative aesthetics

Tiny sea creature unlocks the secrets of healing and aging

Phys.org - 30-Jun-2023

Insights on the evolution of ageing and may help advance regenerative medicine

NHS rolls out new digital health check across England in spring

The Guardian - 28-Jun-2023

To prevent major diseases while making patients’ lives easier & reducing pressure on GP services

Living in green neighborhoods may help you live longer and healthier

The Washington Post - 28-Jun-2023

New study finds people with high access to green spaces were 2.5 years younger in biological age

Bluerock to pioneer first-in-class neuronal stem cell therapy for Parkinson’s disease

BlueRock Therapeutics - 28-Jun-2023

Bemdaneprocel shows positive phase I results, advances to Phase II trial in early 2024

Telos Biotech parent, Cambrian Bio, to develop robust cell therapies for treating age-related diseases

Longevity Technology - 27-Jun-2023

Novel recombinant protein to manufacture biologically fit cells by safely lengthening telomeres

Hunter-gatherer diet unveils incredible gut microbiome diversity

New Scientist - 21-Jun-2023

A study of Tanzania's Hadza people reveals over a thousand new gut microorganism species

Attovia Therapeutics pushing forward the nanobody field with $60 million investment

Longevity Technology - 21-Jun-2023

Plans to leverage exclusive Attobody nanobody platform to develop innovative treatments in immunology and oncology

Novel heart disease treatment given $145m boost with Bitterroot Bio funding

Longevity Technology - 19-Jun-2023

Biotech leverages insights from immunology and cardiology, aiming to dissolve arterial plaques with their flagship asset, BRB-002

Reason reports back from Age-Related Disease Therapeutics Summit 2023

Fight Aging! - 16-Jun-2023

Many people believe lots of clinical trials of novel therapeutics targeting mechanisms of aging will start up in the next few years

Synthetic human cells revolution: bit.bio achieves mass production breakthrough

iNews - 15-Jun-2023

Paves way for potential medical research, organ manufacturing and disease treatment advances

Debunking temporal scarcity: transhumanist vision of radical life extension

Newsweek - 14-Jun-2023

Zoltan Istvan argues that technology will fundamentally shift the equation

AI unveils economical pathway to discover new senolytics to combat age-related diseases

The University of Edinburgh - 14-Jun-2023

Artificial intelligence identifies herbal compounds to safely eliminate senescent cells

Groundbreaking handheld bioprinter unveiled with multiple bioink cartridges

Medical Xpress - 13-Jun-2023

Improves in situ tissue and organ regeneration, promising future applications in drug delivery and custom prosthetics

Range Bio garners $5.2m for groundbreaking proteomics tech to revolutionize personalized health

Longevity Technology - 13-Jun-2023

Innovative technology combines synthetic biology, genomics, and machine learning to transform the way diseases are diagnosed and treated

Hanall Biopharma and Daewoong Pharmaceutical join forces with Vincere Biosciences in fight against Parkinson's

Longevity Technology - 12-Jun-2023

Strategic investment aimed at harnessing the power of collaborative innovation and AI in the pursuit of groundbreaking therapeutics

Diabetes medication metformin could lower long COVID risk by 41%, study suggests

New Scientist - 09-Jun-2023

Metformin may function as an anti-inflammatory and potentially reduce the viral load of SARS-CoV-2

Revitalizing ageing stem cells: Unveiling the key to lasting youthfulness

Lifespan.io (LEAF) - 05-Jun-2023

Combination of factors that rejuvenate stem cells holds promise for aging and muscle-wasting diseases

The bowhead whale's secret to living over 200 years: Remarkable DNA repair mechanisms

Live Forever Club - 30-May-2023

Exceptional longevity and resistance to cancer holds potential implications for human health and ageing

Game-changing bacteriophage could revolutionize gene therapy

New Scientist - 30-May-2023

Ability to carry vast amounts of DNA and other molecules promises substantial advancements in gene and cell therapies

Proprietary GHK-Cu formulation by Yuvan Research clinically proven to increase skin collagen density

Live Forever Club - 29-May-2023

Epigenetic breakthrough offers hope for anti-aging therapies, harnessing the power of naturally occurring peptide

UNITY Biotech's lead compound lags behind the Regeneron’s eye drug

Biospace - 27-May-2023

UBX1325 showed disappointing results in phase II macular degeneration trial - further analysis is required

Hevolution Foundation allocates over $20 Million to promote aging research through HF-AGE grant program

Live Forever Club - 23-May-2023

Nine innovative projects, spread over seven US institutions, set to receive funding

Summary of Jim Mellon presentation at Longevity Med Summit

Live Forever Club - 19-May-2023

Urges individuals with resources and a desire to contribute positively to humanity to invest in the longevity industry

Longevity Med Summit - Best of the Rest

Live Forever Club - 19-May-2023

Key points from more of the excellent speakers at the summit

Gut instinct: Toddler microbiota linked to future obesity risk

The Guardian - 19-May-2023

Better understanding of composition and changes of gut microbiome could lead to potential interventions

Summary of Fabrizio d’Adda di Fagagna presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Telomeres become sinks of irreparable damage - antisense oligonucleotides could potentially provide a fix

Summary of Daniel E. Martin-Herranz presentation at Longevity Med Summit

Live Forever Club - 18-May-2023

Building a saliva-based epigenetic biomarker for systemic chronic inflammation (SCI)

Unraveling the long-term impacts of metformin on lifespan: a 20-year study

Live Forever Club - 16-May-2023

Extensive analysis reveals an initial benefit to longevity that diminishes, then reverses, over time

Summary of Chris Rinsch presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

Explained the production and mechanisms of Urolithin A, and trial results of Timeline's Mitopure

Summary of Aubrey de Grey presentation at Longevity Med Summit

Live Forever Club - 16-May-2023

A quick introduction to the preventative maintenance approach, LEV Foundation and Robust Mouse Rejuvenation

TechCrunch interviews founders of NewLimit after it received another $40m of funding

TechCrunch - 16-May-2023

Reprogramming the epigenetics of a cell could reverse a significant amount of the functional decline that we see with age

WHO cautions on use of AI language models in healthcare

World Health Organization (WHO) - 16-May-2023

Calls for safe and ethical use of LLMs to protect patients and public health

Summary of Max Unfried presentation at Longevity Med Summit

Live Forever Club - 12-May-2023

VitaDAO has already funded 17 projects - including research areas not supported by traditional government agencies

Summary of Gordan Lauc presentation at Longevity Med Summit

Live Forever Club - 11-May-2023

Glycans are the most neglected molecules of cellular communication

Summary of Andrea Maier presentation at Longevity Med Summit

Live Forever Club - 10-May-2023

The course of organ ageing can be mapped and predicted

Pangenome: a new chapter in human DNA mapping embracing global diversity

BBC - 10-May-2023

Updated DNA map opens doors for more inclusive and effective medical treatments

VitaDAO provides $50,000 funding for ImmuneAGE Bio to accelerate its immune rejuvenation research

Longevity Technology - 10-May-2023

Will use its drug discovery platform to further development of lead compound, IA101

Scientists develop a new method to deliver particles into stem cells

Nano Magazine - 10-May-2023

Groundbreaking method poised to revolutionise regenerative medicine

Unraveling the mysteries of aging: Epigenetic damage and the limits of cellular repair

Live Forever Club - 09-May-2023

Novel theory of biological systemic ageing suggests epigenetic ageing is inevitable

Pioneering longevity researcher joins SIRTLab to accelerate aging interventions

Longevity Technology - 09-May-2023

Nir Barzilai brings his expertise to boost the company's mission to extend healthspan by targeting age-related diseases

Weight loss jab is now approved for NHS use in England

BBC - 08-May-2023

Semaglutide tricks your stomach to feel fuller and more satisfied; may be ineffective after withdrawl

AI-driven breakthrough in senolytic drug discovery

Lifespan.io (LEAF) - 04-May-2023

Machine learning successfully identifies promising senolytic compounds to target ageing and age-related diseases

Live Forever Club becomes latest member of International Longevity Alliance (ILA)

Live Forever Club - 03-May-2023

Organisations share a common mission of healthy longevity for all through scientific research

Biolytica raises CHF 5.25m (US$5.8m) to revolutionize personalized health and longevity through AI-driven data analytics

Live Forever Club - 02-May-2023

Stealth development now public and aiming for multi-million dollar turnover by end of year

Gut bacteria may have little or no impact on risk of chronic diseases or longevity

The Conversation (UK) - 02-May-2023

Further studies required to better characterize the association between gut microbiota and its metabolites

Poop pill: FDA approves first microbiota capsule to fight gut infections

AP News - 26-Apr-2023

Oral formulation offers a simpler way to restore gut balance & combat recurrent C.diff infections

Pioneering Heart Repair Technique: Reprogramming Adult Fibroblasts In Vivo

Lifespan.io (LEAF) - 25-Apr-2023

Potential for manipulating fibroblasts to improve heart healing and regeneration after heart attack

Nuffield Council on Bioethics publishes its "The future of ageing" report

Nuffield Council on Bioethics - 25-Apr-2023

The report sets out an ethical framework and recommendations for research and innovation related to ageing

Biological Age: A Dynamic Response to Severe Stress

Harvard Gazette - 24-Apr-2023

Helping the body recover from stress could contribute to increased longevity

Unity Biotechnology's diabetic macular edema senolytic treatment shows promise at 48-week endpoint

FierceBiotech - 24-Apr-2023

Corporate shift towards ophthalmology puts senolytics head-to-head against existing treatments

Life bio's gene therapy reboots cells, offering hope for vision loss and beyond

GlobeNewswire - 23-Apr-2023

Epigenetic reprogramming restored in primates, now paving way for human trials

Old rats live longer and healthier lives with young plasma injections

Live Forever Club - 21-Apr-2023

2 month life extension is equivalent of giving a 60 year-old human an extra 6 years of healthy life

Maximon Longevity Prize 2023: Awarding Innovative Research Projects that Extend Human Lifespan

Maximon - 20-Apr-2023

Apply now to showcase your translational longevity research and win CHF 50,000

Ageing speeds up gene reading, reducing its accuracy

University of Cologne - 12-Apr-2023

Calorie restriction may extend lifespan by improving the quality of gene transcription

Mortality Postponement and Compression in Older Human Cohorts

Live Forever Club - 11-Apr-2023

Even without rejuvenation treatments, expect to see maximum lifespan record broken by 2060

Nanovery raise 1.85M-develop nanorobots that can detect biomarkers directly in blood serum samples

Digital Health - 11-Apr-2023

Nanorobots make the process cost-efficient and fast, with same level of accuracy compared to tradition method

Gut Microbiome: The Secret to Longevity in Centenarians

Lifespan.io (LEAF) - 06-Apr-2023

A youthful gut microbiome may contribute to enhanced longevity and overall health in people living past 100

Tally Health raises $10 million in seed funding for longevity research

Longevity Technology - 06-Apr-2023

Aims to extend human healthspan and promote impactful lifestyle changes

Online shoppers go alcohol-free with increased availability of non-alcoholic drinks

Independent - 30-Mar-2023

High access to non-alcoholic alternatives may notably reduce alcohol purchases

Eye imaging can track the efficacy of interventions aimed at slowing the aging process

Buck Institute - 28-Mar-2023

Scans to know the eyeAge can provide an actionable evaluation of gero-protective therapeutics

Toxic weed, cocklebur found having anti-aging and anti-inflammatory properties

Medical News Today - 28-Mar-2023

The weed could serve as an all-natural skin care product if turns out beneficial

Review of age predictors published in International Journal of Molecular Sciences

Live Forever Club - 27-Mar-2023

Larger sample sizes will further refine their predictability and improve their use case

Meta-analysis studies relate autophagy mechanism with exercise in humans

Lifespan.io (LEAF) - 22-Mar-2023

The type of exercise can effect autophagy in humans, that in return can be an anti-aging strategy

Telomere length may have protective effects against dementia-provide a pathway for future research

Oxford Population Health - 22-Mar-2023

Associations between telomere length and endophenotypes could help treat neurodegenerative disease

Biophysical Therapeutics starts crowdfunding for its drug that slows ageing by reducing metabolic heat generation

Longevity Technology - 21-Mar-2023

Looking to invest in the longevity industry? Stakes from $100 available on Wefunder platform

Study shows it is critical for stem cells to prevent stress to preserve their health and longevity

News Medical - 21-Mar-2023

Therapeutics to boost regulation of protein homeostasis may be beneficial across multiple organs and pathologies

Endurance Exercise Training May Help Prevent Accumulation of Senescent Cells in Colon Mucosa

Live Forever Club - 20-Mar-2023

Age-related increase in inflammatory markers p16 and IL-6 was not observed in endurance athletes

AKL Therapeutics’ investigational oral senotherapeutics drug APPA beneficial for osteoarthritis

Longevity Technology - 20-Mar-2023

Senescent cells have become one of the most promising targets for healthy aging research

Rubedo's lead compound targets inflammatory skin disease with selective senolytic approach

Business Wire - 20-Mar-2023

Rubedo is planning first-in-human studies in multiple skin indications driven by chronic inflammation

Cellular ageing signs emerge earlier in women than men

New Scientist - 19-Mar-2023

Machine learning analysis of millions of biopsy reports has potential implications for disease risk and treatment

UK life expectancy dropping relative to other countries

Sky News - 16-Mar-2023

Driven by income inequality and resulting larger fall in poorer groups

Hypothalamic protein called menin found to regulate ageing and cognitive deficits

Interesting Engineering - 16-Mar-2023

Supplementing with the amino acid D-serine may reverse some anti-ageing effects

MHRA-trial of new robot that can grow stem cells- to bring new low cost and safe therapies

GOV.UK - 16-Mar-2023

Fully automated Intelligent Cell Processing System to manufacture potentially life-saving treatments

Lifespan.io interviews George Church about recent research and future anti-ageing treatments

Lifespan.io (LEAF) - 14-Mar-2023

Is involved in many longevity companies ranging from improving gene therapy delivery to supplements

Mesoblast develops an injection with stem cells having anti-inflammatory effect to treat heart attack

Freethink - 12-Mar-2023

A new weapon that could give doctors an entirely new way to treat heart failure

Peter Attia comments on Danish metformin study that does not find benefit to general population

Peter Attia website - 11-Mar-2023

Original study was subject to bias due to exclusion of participants who progressed to multiple therapies

SRF Scientists have discovered the "Iron Fist" strategy to deal with senescent cells

SENS Research Foundation - 09-Mar-2023

Scientists are working to bring these new rejuvenation biotechnologies of senolytics to aging humans

Unveiling the future of age reversal: meet Yuri Deigin, founder of YouthBio Therapeutics

Longevity Technology - 08-Mar-2023

Tissue-specific gene therapies & rejuvenating factors to extend lifespan and combat age-related diseases

Neocortical grafting platform in brain repair

Live Forever Club - 07-Mar-2023

Multilayered architecture resulted in physiological and behavioural improvements. Could it help regenerate the ageing brain in future?

Biophysical Therapeutics, company that leverages computational biology, validates new drugs

Longevity Technology - 06-Mar-2023

Lower the metabolic rate and body heat, longer the lifespan, but has double-edged sword nature to it

Calorie restriction and its effect on DNA methylation

Live Forever Club - 03-Mar-2023

Analysis of CALERIE trial shows a slowing down in the pace of ageing, but no immediate reduction in biological age

Shrinking population, with greater proportion being elderly, could rock China's economy

Telegraph - 03-Mar-2023

China’s population could peak at 1.4bn in 2025 then almost drop by half by the end of the century

Thymmune Therapeutics raised $7 million in seed financing

Biospace - 02-Mar-2023

Thymmune aims at developing therapies to treat several autoimmune diseases and organ transplant tolerance

Chroma secures new investment of 135M for Series B in genetic medicines

Biospace - 01-Mar-2023

Epigenetic medicine approach avoids the pitfalls of traditional CRISPR method of gene editing

Five Alarm Bio raises seed investment to discover small molecule anti-aging drugs

Cambridge Network - 27-Feb-2023

No drug candidates yet, but great to see investors willing to support a broad attack on ageing

Restoring glutathione -potential therapy could prevent old impaired stem cells from ever developing

UCLA Health - 27-Feb-2023

Higher levels of glutathione better at muscle repair while low levels of the same are bad at it

Challenging Inflammaging in the Pursuit of Healthy Ageing

Live Forever Club - 24-Feb-2023

Chronic inflammation is lurking behind many age-related diseases, but also offers up many targets to reduce it

Men who have regular quality sleep live about 5 years longer, while women add on two more years

The Guardian - 23-Feb-2023

Not just the number of hours but also the quality of sleep is important to enhance your wellbeing

David Sinclair launches Tally Health with biological age tracking and longevity supplements

Longevity Technology - 23-Feb-2023

Longevity Technology interviews CEO Melanie Goldey

Telomeres encode two novel signaling proteins may change our understanding of cancer and aging

Phys.org - 20-Feb-2023

Blood tests for proteins encoded by telomeres could give information of biological age and cancer

Uncovering the Secrets of Cancer Resistance in the Naked Mole-Rat

Live Forever Club - 17-Feb-2023

Study identifies biological mechanisms including efficient DNA repair, no thymic involution and dampened inflammatory response

Morphoceuticals raises $8M to advance bioelectrical treatment for regenerating tissues or organs

Longevity Technology - 15-Feb-2023

A revolutionary approach in regenerative medicine that could improve quality of life in patients

AgeCurve Ltd uses Cell tree rings and somatic mutation to calculate biological age

Longevity Technology - 13-Feb-2023

Those running geroprotective trials, academic researchers, clinical trial could use Cell tree rings

Analysis of gut microbiome relationship with longevity

Live Forever Club - 12-Feb-2023

A strong genetic correlation between healthy diverse gut microbiome and healthy ageing was found

Exploring mesenchymal stem cell derived exosomal therapy as intervertebral disc degeneration cure

Live Forever Club - 08-Feb-2023

MSCExos shown to improve osteoporosis by promoting osteoclast cell proliferation and formation of blood vessels

Multidomain peptides as base material in the 3D-printing inks promote tissue development

Rice University - 07-Feb-2023

The peptide-3D printing ink could benefit regenerative medicine and medical research enormously

cellvie closes $5.5 million of financing to develop its allogeneic mitochondria therapies

KIZOO Technology Ventures - 06-Feb-2023

Mitochondria dysfunction is linked to several ageing-related diseases, including neurodegeneration, so a big potential market

Partial Cellular Reprogramming in Very Old Mice Doubles Remaining Life Expectancy

Live Forever Club - 03-Feb-2023

Shown to work at a cellular level in humans, too, so a therapeutic could be developed soon

Telocyte secures new investment, taking telomerase gene therapy to the clinic in CVD and more

Longevity Technology - 03-Feb-2023

The researchers will not only focus on CVD or cellular aging but the optimal point of intervention

Rejuvenating blood stem cells can help older adults live younger and healthier

Columbia University Irving Medical Center (CUIMC) - 01-Feb-2023

Arthritis drug named anakinra found to reverse ageing effects in blood in mice

Effects of intermittent fasting: An exploration

Live Forever Club - 31-Jan-2023

12 months of IF results in a range of biomarker improvements, but no significant reduction in inflammatory markers

Reversal of cell senescence using low frequency ultrasound

Live Forever Club - 27-Jan-2023

Novel therapy killed some senescent cells, rejuvenated others, without harming healthy cells

Boosting endogenous collagen production through mRNA, ameliorate skin wrinkling with age

Lifespan.io (LEAF) - 27-Jan-2023

Two promising techniques: mRNA delivery through CNP-created EVs and microneedles for EV application

Use of rilmenidine drug showed lifespan and healthspan benefits in both young and old animals

Longevity Technology - 25-Jan-2023

With a global ageing population, the benefits of delaying ageing, even if slightly, are immense

Open genes-comprehensive database of genes associated with aging and longevity

Lifespan.io (LEAF) - 24-Jan-2023

Open gene database simplifies the search for potential aging therapy targets

Heart's biological age can be delayed by 10 years by an anti-aging mutant gene discovered

Medical Xpress - 23-Jan-2023

Healthy mutant gene can reverse the decline of heart performance in older people

Lifespan.io summarises the proceedings of the Buck Institute's Longevity Summit

Lifespan.io (LEAF) - 20-Jan-2023

Another reminder of the amount of research, with multiple approaches, about to go into clinical trials

New alcohol guidelines in Canada recommend only 2 drinks per week

The Guardian - 18-Jan-2023

Experts debate on risk versus enjoyment, however, people must be aware of the risks associated with long-term alcohol use

Dissociation of longevity targeted cell reprogram and somatic identity loss: An exploration

Live Forever Club - 17-Jan-2023

Most genes regulating cellular rejuvenation were not related to the increased occurrence of cancer

Gut microbiota in mice influence brain's dopamine levels, influencing the motivation for exercise

Lifespan.io (LEAF) - 17-Jan-2023

The study highlights the diversity of microbiota and their importance for human health and fitness

Gut microbiome linked to brain damage and neurodegeneration in mice

EurekAlert! - 12-Jan-2023

Modifying gut microbiota with antibiotics reduced inflammation and tau-linked damage

Lifespan.io talks to Aubrey de Grey to find out more about LEVF's Robust Mouse Rejuvenation project

Lifespan.io (LEAF) - 10-Jan-2023

Round 1 testing rapamycin, senolytic, HSCT & mTERT - could start seeing interesting results within 6 months

Smart contact lens setback: Mojo Vision pivots to MicroLED displays

The Verge - 07-Jan-2023

MicroLED tech could revolutionize the display industry but is still in its early stages of development

Genome length and the relationship with ageing: An analysis

Live Forever Club - 06-Jan-2023

Identifies a new target for ageing therapeutics - maintaining the abundance of long RNA transcripts

Longevity Technology speaks to BioAge's CEO about clinical trial progress

Longevity Technology - 06-Jan-2023

Had success in reducing muscle atrophy and discovered novel class of molecules to target cognitive decline

Microbiome and metabolic biomarkers can predict who will lose the most weight

Stanford School of Medicine - 04-Jan-2023

Soon there will be a test to check what the best diet is for your individual microbiome

Nuclear homeostasis contributes to promote longevity and fertility, IMBB scientists

Institute of Molecular Biology and Biotechnology (IMBB-FORTH) - 27-Dec-2022

Cells fundamental quality control mechanism to safeguard the nucleus-promote longevity and fertility

SIRT6: Ageing, Metabolism, and Cardiovascular Diseases - A Review

Live Forever Club - 20-Dec-2022

SIRT6 has a vital role in cell metabolism which could lead to therapeutics for controlling senescence

Cellular Senescence Network (SenNet) to identify and characterize senescent cells

Nature Aging - 20-Dec-2022

Grand plan includes creation of imaging datasets, new tools, techniques, and biomarker panels

Mutated mtDNA acts as a molecular target for therapeutic treatments of age related diseases

University of Cologne - 16-Dec-2022

Targeting and eliminating mutated mtDNA by subjecting it to autophagy with rapamycin been successful

American football players age a decade faster than the general population

Independent - 13-Dec-2022

Further studies to examine the phenomenon for age-related illnesses among former players

Exploring cellular enlargement as a new hallmark of aging

Live Forever Club - 12-Dec-2022

Size of various cells (including red blood, adipocytes, brain, heart) is seen to increase with age-related diseases

Therapeutic applications of base editing clears girl's leukemia

BBC - 11-Dec-2022

Base editing can soon be a part in taking control of our genomes to fight genetic diseases

Turn Bio reverses multiple hallmarks of aging in human skin

CISION PR Newswire - 06-Dec-2022

Epigenetic reprogramming restores the production of collagen and elastin

Large scale study identifies new risk loci associated with CAD (coronary artery disease)

University of Oxford - 06-Dec-2022

The study outlines a list of genes and genetic variants for future study of common diseases

Microbes in your gut may affect your mental health

Oxford Population Health - 06-Dec-2022

Gut bacteria indirectly produce hormones that influence the brain and can cause depression

Tissue transplants as standard treatments for Parkinson’s- a promising approach

The Guardian - 04-Dec-2022

This one-off treatment could nullify the complications that you get with chronic medications

Isomorphic Labs on an expansion drive for its AI-enabled drug discovery

Financial Times (FT) - 03-Dec-2022

Plan is to build a generic platform then work with major pharma companies to take them to market

Targeting senescent cells could be a useful approach for slowing/treating Alzheimer’s disease

Salk Institute - 01-Dec-2022

How senescent neurons lead to Alzheimer’s disease, effect on removal and drugs needed for therapy

CRISPR based PASTE (Programmable Addition via Site-specific Targeting Elements) tool designed

MIT Media Lab - 24-Nov-2022

The new PASTE tool replaces faulty genes in a safer and more efficient way

RxCelerate acquires Methuselah Health and launches proteomics platform ProQuant

Longevity Technology - 23-Nov-2022

Next-generation proteomics technology to accelerate drug discovery and development

Correlation found between biological aging and cognitive decline using epigenetic clocks

Lifespan.io (LEAF) - 21-Nov-2022

The midlife study showed that the cognitive decliners age faster

Jeune Aesthetics moves to the Phase 2 trial for fine lines and wrinkles

Biospace - 17-Nov-2022

Targeted gene-delivery hold potential in replenishing the skins key protein, to treat fine lines

Mogrify and Astellas collaborate on novel gene therapy for hearing loss

Labiotech - 17-Nov-2022

Breakthrough approach to regenerate new cochlear hair cells that enable hearing

Leprosy bacteria may hold the secret to safely repairing and regenerating the body

BBC - 16-Nov-2022

Biological alchemy by leprosy bacteria-converts one type of bodily tissue into another

£500K in 4th round funding to scale-up Magnitude Biosciences' C. elegans research services

Magnitude Biosciences - 14-Nov-2022

Advances in AI is great, but this sort of automation is what will create the data it needs to find new longevity drugs

Pandemic made Britons less optimistic towards living to a 100 years as compared to those in 2019

Ipsos - 14-Nov-2022

We need much more public education that living longer, healthier lives is just round the corner

Novel experiment explores a new way of reducing senescent cell burden

Live Forever Club - 12-Nov-2022

BDNF-TrkB pathway shows a lot of promise in lowering senescent cells in older organs

Maintain your muscle strength across the lifespan to prevent age-related diseases

News Medical - 10-Nov-2022

The weaker the grip strength, the older is your biological age

Researchers found a missing genetic link that helps melanoma cells defeat mortality

EurekAlert! - 10-Nov-2022

Mutations in a telomere binding protein provide a new approach to treat melanoma and other cancers

Extracellular vesicles from young stem cells have a rejuvenating effect in vitro and in vivo in mice

Lifespan.io (LEAF) - 08-Nov-2022

This approach did not kill the senescent cells instead, it was senomorphic

Juvena Therapeutics receives $50M to uncover therapeutic links between secreted proteins and diseases

Biospace - 08-Nov-2022

Its a fully integrated approach for developing biologics for chronic and age-related diseases

First clinical trial to transfuse lab-grown red blood cells

The Jerusalem Post - 07-Nov-2022

A breakthrough treatment for people requiring blood transfusions in near future

Five Alarm Bio to develop drug treatment not to cure ageing but improve healthy lifespan

Cambridge Independent - 04-Nov-2022

The company aims at treatments for a range of diseases associated with ageing and disabilities

Lifespan.io interviews NaNotics' CEO Lou Hawthorne to find out more about Nanots

Lifespan.io (LEAF) - 04-Nov-2022

Many conditions could be improved by removing signalling that prevents cells operating at their best

Longevity Technology interviews Frequency Tx' CSO about activating innate progenitor cells

Longevity Technology - 01-Nov-2022

Cells are already in the right place, just need the right kick to help repair the body when needed

Reprogramming by cellular rejuvenation in mice increases lifespan and health

Lifespan.io (LEAF) - 01-Nov-2022

Partial reprogramming extends healthspan and lifespan by single or lifelong treatment

Scientists unveil role of genomic 'dark matter' in cancer detection and treatment

BBC - 27-Oct-2022

Early but promising finding that epigenetic changes alter the growth of cancer cells

Stem cell biotech MoglinBio secures seed investment

KIZOO Technology Ventures - 26-Oct-2022

Kizoo is focused on rejuvenation biotech so it must see potential in normalizing CDC42 activity

Universal epigenetic clocks predict true biological age in any mammalian species

Live Forever Club - 25-Oct-2022

Shared methylation patterns across mammals showed an association between ageing & development process in evolution

Coinbase CEO selling 2% of his shares to free up over $50m for longevity investments

Lifespan.io (LEAF) - 25-Oct-2022

There is a strange overlap in interests between crypto people and longevists - and long may that benefit the industry!

Organoids-hair follicle morphogenesis in hair loss treatment

Independent - 22-Oct-2022

Hair cells generated in vivo, potentially promising to reverse hair loss disorders and baldness

Reason reports back from October's Rejuvenation Startup Summit

Fight Aging! - 19-Oct-2022

Some really exciting developments with quite a few in clinical trials

Senolytics-a risky proposition in aging and repair mechanisms

Lifespan.io (LEAF) - 19-Oct-2022

The study is a caution for scientists engaging in self-experimentation with senolytics

Microbiome differences were associated with increased frailty, not chronological age

The Jackson Laboratory (JAX) - 19-Oct-2022

Skin microbiome emerged as the primary reservoir for infection risk associated with frailty

England and Wales see slight increase in life expectancy in 2021 - official figure to follow

BBC - 17-Oct-2022

Only 4 out of 31 countries studies have seen their period life expectancy recover since 2020

$15M raised for series A round for robotic dental procedures by Cyberdontics

TechCrunch - 17-Oct-2022

Cyberdontics-robot cuts the tooth and fabricates a prosthetic at the same time-efficacy and speed

Calico-Terray Therapeutics collaborate to discover and advance therapeutics for diseases of aging

Calico - 12-Oct-2022

Terray’s novel microarray technology, combines wet lab and computer-driven drug development

Vita Therapeutics raised $31m to develop treatment for genetic diseases and cancers

Business Wire - 12-Oct-2022

Cell therapies aiming not only to correct the genetic defect but also repair and heal the muscle cells

Mitochondria boosting therapy rejuvenates immune system of mice

Longevity Technology - 11-Oct-2022

If successful in humans it would improve the outcome of many age-related diseases

Focal Biosciences launched by PSI and Apollo Health Ventures

Business Wire - 11-Oct-2022

Aims to treat age-related diseases using advanced cellular reprogramming technologies

Same chronological age women are biologically younger than the men

News Medical - 10-Oct-2022

Differences in biological aging between men and women - frequent smoking and larger body size of men

University of Alabama at Birmingham looking for IF and CR participants for new study

University of Alabama at Birmingham (UAB) - 10-Oct-2022

Will look at whether health and ageing improves with calorie restriction or intermittent fasting

Metformin misinterpreted as antiaging drug via animal studies, TAME heads for future trials

SENS Research Foundation - 04-Oct-2022

More than 90% of drugs safe and effective when tested in experimental animals fail in human testing

$2.5M seed financing round closed by Cleara Biotech-targets cellular senescence

Longevity Technology - 03-Oct-2022

Cleara’s novel FOXO4-based treatment approach-ability to eliminate biomarker-positive scarred cells

People with vulnerable mental state age faster than smokers

Interesting Engineering - 27-Sep-2022

Psychological component should not be ignored in aging studies as they impact on biological age

Healthy Longevity Medicine Society launches to promote longevity medicine

Longevity Technology - 27-Sep-2022

Looks like it will act as an interface between longevity researchers and clinicians

$100M fund - Life Extension Ventures might back startups working on longevity

TechCrunch - 18-Sep-2022

Founders are excited to find the impact when software intersects science

Longevity Technology interviews cellvie CEO, Alex Schueller, about therapeutic mitochondria

Longevity Technology - 14-Sep-2022

Initially targeting ischemia-reperfusion injury, TMT has potential to treat multiple age-related diseases

$72m funding launching Pretzel Therapeutics pioneering mitochondrial therapies

Biospace - 12-Sep-2022

Pretzel targets genome correction, genome expression modulation and mitochondrial quality control

Negative impacts of khavinson peptides and melatonin on thymic regrowth

Fight Aging! - 12-Sep-2022

Self-experiment results- detrimental due to frequent doses or simply bad combo

Systemic Bio develops custom-made organ models from human cells

3D Printing Industry - 09-Sep-2022

New firm launched by 3D Systems to advance drug discovery and testing process

Umbilical cord blood derived plasma improves health biomarkers

Lifespan.io (LEAF) - 06-Sep-2022

Plasma concentrate alters methylation clock reducing biological age

Our sleep age could predict our mortality

Independent - 03-Sep-2022

Higher sleep age reflected in increased sleep fragmentation, it may be a marker of future health

Researchers claim to have uncovered secret to immortality in jellyfish

Futurism - 01-Sep-2022

what this means to humans? - a possibility to treat overwhelming aging disorders

Statistics shows steep decline in life expectancy - largely driven by COVID-19

BBC - 31-Aug-2022

US records the lowest since 1996 and UK fell for the first time in 40yrs

NICE - faecal transplants can be offered for hard-to-treat C. difficile

BBC - 31-Aug-2022

A solution to reduce both antibiotic usage and antimicrobial resistance

Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression

Lifespan.io (LEAF) - 25-Aug-2022

TPE causes systematic rejuvenation in human body by influencing multiple factors

Ageing-related drug screening made easy and reproducible with automated tech

Longevity Technology - 18-Aug-2022

Camera on each petri dish captures healthspan of many worms simultaneously

Regenerative therapies and senolytics help to rejuvenate the heart’s capacity to regenerate

Longevity Technology - 17-Aug-2022

Eliminating senescent cells rejuvenates the heart's capacity for regeneration in mice

Soluble plastic microneedles to codeliver RAPA and EGCG nanoparticles to regrow hair

Lifespan.io (LEAF) - 16-Aug-2022

Microneedle-based hair treatment substantially more effective than topical application

AgeX credit running out with substantial doubt it can continue

FierceBiotech - 15-Aug-2022

Let's hope their research is either successful for the company or its successors

National Resilience will collaborate with Mayo's Center for Regenerative Medicine

Mayo Clinic - 15-Aug-2022

Mayo Clinic advance regenerative technologies from discovery science to early phase clinical trials

Data from Phase 2 BEHOLD study of UBX1325 in DME patients-Unity Biotechnology

Ophthalmology Times - 12-Aug-2022

Statistically significant treatment effect for both BCVA and CST was seen at both 12 and 18 weeks

72% of Induced pluripotent stem cell lines were reported to have major UV damage

University of Cambridge - 11-Aug-2022

Whole genome sequencing-necessary to validate Stem cell lines used for therapy

Mitophagy activators shown to increase lifespan and healthspan in C.elegans

Longevity Technology - 10-Aug-2022

Vitalunga to usher the novel drug for hepatocellular carcinoma clinical trials

Review identifies thousands of genes that drives skin ageing

Lifespan.io (LEAF) - 10-Aug-2022

Addresses challenges like phenotype list compilation and associated genes

VascVersa raises 500k pounds in seed round for developing a cell therapy product

Belfast Telegraph - 09-Aug-2022

VascVersa is committed to regenerative medicine for people suffering from ischaemic diseases

Study shows the link between hibernation and longer lifespans in bats

College of Computer, Mathematical, and Natural Sciences (CMNS) - 09-Aug-2022

Overlap between the hibernation genes and the longevity genes links hibernation with longer life

Can infusion of young blood be beneficial for clinical anti-aging approaches?

Mary Ann Liebert, Inc. - 04-Aug-2022

Infusions of young blood plasma into mice, does not increase their lifespan

Employing native bacteria as ideal chassis for therapeutic delivery and cure

UC San Diego School of Medicine - 04-Aug-2022

Re-engineered native bacteria serve as chassis to introduce therapeutics into the gut

SIRT6, the longevity sirtuin proven to enhance healthy longevity

Longevity Technology - 03-Aug-2022

SIRT6 Activator is a safe way to repair the genetic damages that may occur due to aging

Excessive alcohol consumption may age you faster by accelerating your biological age

Interesting Engineering - 28-Jul-2022

Alcohol consumption causes telomere shortening, leading to several age-related diseases

Epigenetic age acceleration could be used as a biomarker for healthy longevity

University of California, San Diego (UCSD) - 27-Jul-2022

Accelerated biological aging associated with lower odds of living healthy and longer

Phase 2 clinical trial of lead drug candidate MYMD-1- a therapy for delaying aging

Business Wire - 26-Jul-2022

Sarcopenia drug trial shows no evidence of toxicity or safety issues

Impacts of inequality affects the poor and increases the risk of dying from lung disease in UK

The Guardian - 25-Jul-2022

Poorest 10% of patients are now five times more likely to die with lung disease than the wealthiest

ForSight Robotics raises $55M for fully robotic cataract surgery

FierceBiotech - 22-Jul-2022

ForSight Robotics main goal is to democratize sophisticated eye treatment procedures globally

Breakthrough gene therapy offers cure for a rare bleeding disorder heamophilia

BBC - 21-Jul-2022

Trial results were positive but cautioned the use until proven safe and effective

Restructured mitochondrial metabolism linked to survival of human eggs

STAT - 20-Jul-2022

Complex I production temporarily halted in quiescent oocytes, promoting fertility

MitoRx Therapeutics' CEO shares insights on fundraising and pitching to investors

UK Innovation & Science Seed Fund - 20-Jul-2022

Effectively communicating to investors will translate an ideology into a social benefit

Mitochondrial transplants show efficacy in achieving longevity in humans

Lifespan.io (LEAF) - 19-Jul-2022

Mitochondrial transplant raise energetics of the body, so it can withstand longevity treatments

Age-related changes in retina linked to decline in 'youth' protein

National Eye Institute (NEI) - 18-Jul-2022

Aging associated retinal disorders linked to loss of protective protein

Shorter lifespan in men linked with loss of male sex chromosome while aging

The Conversation (UK) - 14-Jul-2022

Understanding how Y chromosome may contribute to age-related diseases can help prevent them

Alzheimer’s disease can be treated in blood circulation instead of in the brain

UTHealth - 14-Jul-2022

A target for Alzheimer’s disease therapy may lie in plasmapheresis or blood dialysis

NIH awarded OMRF $3 million to study anti-aging abilities of a diabetic drug

Oklahoma Medical Research Foundation (OMRF) - 13-Jul-2022

Investigation of ability of metformin, a diabetic drug to slow the process of aging

EA-2353, a photoreceptor regeneration treatment for blindness, by Endogena Therapeutics

Labiotech - 12-Jul-2022

Endogena's gene-independent treatment has shown advantages in retinitis pigmentosa

Biohybrid material that mimics natural skin developed using 3D printing

3D Printing Industry - 12-Jul-2022

Soft yet tough biohybrid composites similar to lifelike skin may have productive potential

The genetics of successful ageing: unlocking longevity genes in humans

Live Forever Club - 11-Jul-2022

APOE and FOXO3A had significant impact on longevity, but environmental factors also determine the fate of health while ageing

Relation between seasoning cooked food with salt and premature death revealed

The Guardian - 11-Jul-2022

Not adding extra salt to already prepared foods could be a healthier option

Advancements in organ biofabrication may lead to build human heart for transplant

Harvard University - 07-Jul-2022

Helical structure of heart muscles helps understand the functioning of heart

Urolithin A can increase mitochondrial health in living joint tissue and improved mobility

Business Wire - 07-Jul-2022

Mitopure can improve mitochondrial health and counteract age-related muscle function decline

HTR in Drosophila somatic cells using nikase and CRISPR genetic editing tools

Genetic Engineering & Biotechnology News (GEN) - 05-Jul-2022

CRISPR genetic editing tools may be helpful in genetic repair

ECM proteins help to develop more robust methods for generation of heart cells

University of Wisconsin-Madison - 01-Jul-2022

ECM proteins play significant roles in hPSC adhesion, growth & cardiac differentiation

Old skin transplants in young organisms reverses aging, show rejuvenation

Lifespan.io (LEAF) - 01-Jul-2022

Upregulation of VEGF-A could be a potentially effective anti-aging therapy

New insight on the accumulation of senescent cells in humans

UPMC - 30-Jun-2022

Oxidative DNA damage induce rapid senescence compared with shorter telomeres from repeated cell divisions

Telomerase-positive human urine-derived stem cells optimal for tissue regeneration

Neuroscience News - 28-Jun-2022

Stem cells in human urine have major advantages over stem cells from other sources

Humanoid robot and AI potentially efficient in regenerating retinal cells

Phys.org - 28-Jun-2022

Automated design and execution can increase efficiency and speed of research

Racing for the lead... Underdog becomes Cyclarity Therapeutics

Longevity Technology - 20-Jun-2022

Also announces move to Buck Institute for Research on Aging

mRNA delivers mutated proteins - regenerates cardiomyocytes post a heart attack

University of Houston - 16-Jun-2022

Stemin and YAP5SA notably restores normal cardiac pumping in mice

JuvLife Division raises 3.7 million euros for making antiaging product with Chrysea

Longevity Technology - 13-Jun-2022

Metabolites induce autophagy, stimulate cellular regeneration for healthy ageing

Qubit pharmaceuticals secures 16.1 million euros in seed round to revolutionize drug discovery

The Quantum Insider - 10-Jun-2022

Developing a software platform that uses quantum computers to accelerate the discovery of new drugs

Exeter's company SENISCA raises £2 million to treat age-related chronic diseases

University of Exeter - 09-Jun-2022

Funding might allow RNA-based rejuvenation tech to enter ex vivo lab tests

Ageing versus longevity: epigenetic age correlated with only a few ageing hallmarks

Live Forever Club - 08-Jun-2022

Mitochondrial dysfunction & stem cell exhaustion accelerated the epigenetic clock, but senescent cells & telomere length did not

Lyfspn recruiting in USA for plasmapheresis trial using 5% human albumin

Longevity Technology - 08-Jun-2022

No mention of the Conboys, but it looks like it's based on their plasma dilution research

High optimism associated with longevity and healthy aging across diverse groups

Harvard T.H. Chan School of Public Health - 08-Jun-2022

Positive physiological factor extends life expectancy of women beyond 90

Hevolution Foundation to spend $1 billion annually on the biology of aging

MIT Technology Review - 07-Jun-2022

Considering funding a $100 million age reversal X Prize and the TAME(metformin) trial

Healthy lifestyle practices boosted 6 years of life for healthy 40-year-olds

SciTechDaily - 07-Jun-2022

Lifestyle improvements- a positive impact on health despite chronic health conditions and older age

Not just vision - diet and eye health is linked to aging in fruitflies

Buck Institute - 07-Jun-2022

Staring at gadget screens at night affects circadian clock and in turn lifespan

Insilico Medicine series D funding to grow its pipeline and create an AI-driven robotic drug discovery laboratory

Longevity Technology - 06-Jun-2022

Big data combined with laboratory automation - the pace of drug discovery is about to take off!

Senolytics may abate accelerated aging of cancer patients as seen in mice

Lifespan.io (LEAF) - 06-Jun-2022

Radiation-induced damage may lessen by removing senescent cells but senolytics may not reverse the damage

Lento bio to launch anti-glycation drugs targeting anti-aging and presbyopia

Ichor Therapeutics - 06-Jun-2022

Lento Bio research into molecular aging damage by accelerating clinical assets

Height may be an unrecognised non-modifiable risk factor for several health issues

The Guardian - 02-Jun-2022

Largest height study ever: being tall increases risk of peripheral neuropathy, lowers heart risk

Blood composition explains the reason for frailty in older people

The Guardian - 01-Jun-2022

Treatments targeting faster-growing stem cells & low-quality blood cells can promote healthy ageing

$100 genome - natural sequencing using NGS by UG 100 and raises $600M

GEN News - 01-Jun-2022

Cost-efficient whole genome-sequencing at a price of $1/Gb using NGS

Epigenome editing - technology safer and reversible than CRISPR

Science - 01-Jun-2022

Leaves DNA sequence unaltered while retaining the ability to specifically home

Longer lifespan lies in the mechanisms regulating gene expression

EurekAlert! - 31-May-2022

Pluripotency network can have negative and positive lifespan effects

Young blood factors identified that rejuvenate old HSPCs in mice

Chinese Academy of Sciences (CAS) - 30-May-2022

Could eventually lead to treatments that reinvigorate immune cell production

The anti-malarial drug chloroquine increases lifespan in male mice

Lifespan.io (LEAF) - 30-May-2022

Chloroquine significantly interferes with the fundamental mechanisms behind autophagy

New algorithm recognises senescent cells using physical morphology

Lifespan.io (LEAF) - 26-May-2022

in vivo analysis in mice confirms the imaging results against p21 biomarker

Infusing aged mice with young cerebrospinal fluid improves memory

Lifespan.io (LEAF) - 24-May-2022

Oligodendrogenesis and memory function in the aged brain can be improved by young CSF

Epigenetic age varies when people are exposed to significant stress

Lifespan.io (LEAF) - 23-May-2022

PhenoAge and GrimAge show epigenetic aging has downstream biological consequences

Lifespan of middle-aged mice increased by a third with telomerase gene therapy

CISION PR Newswire - 19-May-2022

Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleus

Buck researchers discover mitochondrial protein that can increase lifespan

Buck Institute - 18-May-2022

In yeast, increasing Tom70 delays ageing related mitochondrial dysfunction

Amazentis’ proprietary Urolithin A-clinically proven to improve muscle function

EurekAlert! - 17-May-2022

Mitopure will be offered inside Nestlé Health Science products

Synergy of stem cell rejuvenation and senolytics promote longevity in fruit flies

Live Forever Club - 14-May-2022

Combined approach surprisingly eliminated the negative effects of individual treatments

Lifespan.io interviews João Pedro de Magalhães about theories of, and curing, ageing

Lifespan.io (LEAF) - 13-May-2022

The one thing I hope he's wrong about is that it won't happen in his lifetime - we just need some exponential oomph!

Selah Therapeutics launched to focus on ketone-based therapies for heart disease

Longevity Technology - 13-May-2022

Treatment options for diseases of aging - from the makers of metabolic switch

Viral-vector gene therapies could unlock healthy life extension in humans

Lifespan.io (LEAF) - 12-May-2022

Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years old

Non-invasive technique for gut health monitoring

Swiss Federal Institute of Technology (ETH Zurich) - 12-May-2022

Gene modification in bacteria using CRISPR array provide direct information of active gut genes

Faster walking associated with longer telomeres, could improve health and lifespan

Lifespan.io (LEAF) - 11-May-2022

We know exercise keeps people healthier and this may be just one of the underlying mechanisms

Anti-ageing substance in sea squirts improved brain health in older mice

Neuroscience News - 11-May-2022

Plasmalogen supplement reversed ageing signs in mice; might as well keeps you young

Benjamin Le Calvé as the new Chief Scientific Officer of Starkage Therapeutics

StarkAge Therapeutics - 10-May-2022

Le Calvé will chair the Scientific Advisory Board and the Management Committee

The Observer interviews Morgan Levine about ageing and her move to Altos Labs

The Guardian - 07-May-2022

When it comes to lifespan, you cannot blame 100% on genetics, just 10-30%

Verve Therapeutics' gene editing therapy may cure heart attacks once and for all

Bloomberg - 06-May-2022

Trials underway to test the safety, but affordability and acceptance of gene therapy are major concerns

Low-calorie diet during active period of the cycle increased lifespan in mice

UT Southwestern Medical Center - 05-May-2022

Triple the effect seen over simply restricting calorie intake

Study in mice says faecal transplants could possibly reverse ageing

University of East Anglia (UEA) - 04-May-2022

Gut microbiome dictates and decides the health of your gut, eyes, and brain

Lab-made synthetic nerve transmits signal within a microsecond

Chemical & Engineering News (C&EN) - 28-Apr-2022

Light-driven artificial nerve could one day be used for medical devices or implants to cure diseases

First ever organ-on-a-chip functions like the human's body

Columbia Engineering - 27-Apr-2022

Opens way for personalized therapy, drug testing, and clinical extrapolation

New longevity startup MitoRx Therapeutics is developing mitochondria protective drugs

Longevity Technology - 25-Apr-2022

Targeting age-related diseases, the company's pre-clinical compounds to progress to the clinic

miniPUMP - the next-best personalised human heart model for drug testing

New Atlas - 25-Apr-2022

Your cells as your own "organ-on-a-chip" model for heart disease

CARMAT raised €40.5 million - set to resume the artificial heart production

Longevity Technology - 21-Apr-2022

Aeson could prolong lives of patients awaiting a human heart transplant

Epigenetic age identifies risk of dementia later in life

Feinberg School of Medicine - 20-Apr-2022

Epigenitic and brain aging markers provide insights on accelerated cognitive decline

Satellite Bio raised $110M to push its tissue therapies to the clinic

FierceBiotech - 20-Apr-2022

Bioengineered implanatable tissues can repair or replace diseases organs

Poor women in England are dying younger, reveals a life expectancy report

The Guardian - 17-Apr-2022

Female life expectancy in poorest areas was 7.7 years lower than richest areas of England

YouthBio Therapeutics unveils its board, with João Pedro de Magalhães as CSO

CISION PR Newswire - 14-Apr-2022

Another company enters the cellular reprogramming race - hopefully at least one will cross the finishing line

Mammals have similar number of DNA mutations whatever their lifespan

BBC - 14-Apr-2022

Shorter lived animals have higher rate of mutations - could explain lower rates of cancer in larger mammals

Turn Bio raised funds to usher epigenetic reprogramming from bench to bedside

Biospace - 11-Apr-2022

mRNA technology-reset aging to extend health span and improve quality of life

Biological age of human skin cells reduced by 30 years (transcriptome and methylation clocks)

BBC - 08-Apr-2022

Transient reprogramming is progressing fast - how long before the first skincare product is launched?

SENISCA to reverse senescence by targeting RNA splicing patterns

Longevity Technology - 08-Apr-2022

Lorna Harries details significant breakthroughs at fourth annual Longevity Leaders World Congress

Elastrin Therapeutics secures $10 million of funding for its calcification removal platform

Forever Healthy Foundation - 07-Apr-2022

Initially targeting stiffened arteries in cardiovascular disease, this could have wider implications

Alzheimers' treatment with stem cells is proven safer in Phase 1 clinical trial

Lifespan.io (LEAF) - 07-Apr-2022

Lomecel-B targets homing and microglia recruitment rather than differentiation

Retro Biosciences launched to add 10 years to human lifespan

Biospace - 06-Apr-2022

$180M fund will support research on cellular reprogramming, autophagy & plasma-inspired therapeutics

Brain charts: showing the incredible growing and shrinking brain ability

University of Cambridge - 06-Apr-2022

Mapping the brain and creating charts could be used as a helpful clinical tool for other clinicians, psychiatrists and researchers

99% of people in the world are breathing polluted air

Independent - 04-Apr-2022

WHO calls for the immediate transition from fossil fuel use to clean energy

NovaXS Biotech develops smart, painless, needle-free injections

TechCrunch - 31-Mar-2022

Innovative tech to make self-administered therapies easier and more accessible

Genflow's sirtuin gene therapy can make old liver young again

Longevity Technology - 29-Mar-2022

Currently exploring the SIRT6 potential with University of Rochester’s Aging Research Center

Gene therapy gel heals wounds in people with rare genetic skin condition

New Scientist - 28-Mar-2022

Positive results in clinical trials provide hope for conditions that currently have no specific treatments

Senior UCLA scientists public states aim to fight aging to impact numerous diseases

University of California, Los Angeles (UCLA) - 24-Mar-2022

Great to see the concept of reversing aging becoming a mainstream ambition - it hasn't always been that way!

Revel pharmaceutics raised $8.4M to push enzyme therapies to clinic

KIZOO Technology Ventures - 17-Mar-2022

Funds will be used to develop enzymes that repair collagen and reverse ageing or disease

Oral senolytics boosts geroprotective protein in mice and humans

Mayo Clinic - 15-Mar-2022

Dasatinib+Quercetin restores a-klotho protein, which could combat ageing and disease in older people

Between 1993 and 2011, most increase in life expectancy was disease free years

Science Daily - 15-Mar-2022

Exception was for people with a cognitive impairment, study by Newcastle University shows

Yellow-bellied squirrels stop ageing process while hibernating every year

Technology Networks - 08-Mar-2022

Organ preservation and life extension is possible when humans could also hibernate

Your organs and systems are ageing at different rates, new study finds

Technology Networks - 08-Mar-2022

Biological age differs from one organ to other, suggesting practical use of multiple clocks

Long-term partial reprogramming reversed ageing process in mice

The Guardian - 07-Mar-2022

Yamanaka factors restored youthfullness in aged cells, raised hope for new anti-ageing therapies

University of Washington launches Rapamycin Study

Live Forever Club - 05-Mar-2022

Have you been taking rapamycin supplements recently? Please consider contributing to this study.

Spinal cord engineered from belly fat tissue could cure paralysis

Longevity Technology - 04-Mar-2022

Treatment was successful in mice, and now gears up to treat paralyzed humans

Tornado, new longevity biotech developing safer and effective mTOR inhibitors

Longevity Technology - 03-Mar-2022

Different flavours of rapalogs targeting different age-related conditions

Maximon announces 50,000 CHF (approx. £40K) Longevity Prize for Translational Research

Maximon - 01-Mar-2022

And by longevity it means "substantially increase health span or life span" - apply now!

UK ranks second for lung disease deaths in Western Europe, with more negative impact on poor people

BBC - 28-Feb-2022

UK charity seeks funding opportunities for better treatment and research

Longevity.Technology looks at 12 key companies running age-related disease clinical trials in 2021

Longevity Technology - 25-Feb-2022

Approaches include senotherapeutics, stem cells and mitochondria. Eye disease is a common first target.

Human bones grown from patient's own stem cells using sound waves

New Atlas - 21-Feb-2022

Painless bone regeneration with a faster, easier and effective approach

Volumetric 3D bioprinted tiny liver functions just like a human liver

3D Printing Industry - 17-Feb-2022

Paving the way for bioprinted livers and personalized drug screening for liver diseases

Limiting calories rewires immuno-metabolic function for longer healthspan in humans

GEN News - 14-Feb-2022

Protein produced by macrophages was identified as a key player of calorie restriction

Synchron gets investment from Neuralink cofounder

Futurism - 07-Feb-2022

Appears to be ahead in the race as already started human trials

SenoStem project to investigate whether prior delivery of senolytic improves stem cell treatment

SENS Research Foundation - 07-Feb-2022

Both are leading first generation longevity treatments - even better if they strengthen each other

Hair grown from your own cells may treat baldness

New Atlas - 06-Feb-2022

dNovo converts any cell to hair stem cells, and have already grown hair in mice

João Pedro de Magalhães provides cautious optimism in this Longevity Technology interview

Longevity Technology - 04-Feb-2022

Maybe a longevity drug within 5 years, but still lots more research needed into process of ageing

NHS offers the world's most expensive drug for children with a rare disease

BBC - 04-Feb-2022

Libmeldy is life-saving gene therapy now available for use in England

Google's parent company launched Isomorphic Labs to discover new drugs using AI

TechCrunch - 04-Feb-2022

Building from Deepmind's AI research, Isomorphic promises medical breakthroughs

A natural cholesterol metabolite with senolytic effect in mice and humans

Buck Institute - 02-Feb-2022

New class of senotherapeutic drugs that could possibly target various diseases and ageing

ChromaDex releases results of clinical trial demonstrating anti-inflammatory effects of NR

Longevity Technology - 28-Jan-2022

Gold-standard trial included 35 participants taking 1000mg of NR (or placebo) for a week

Arda Therapeutics, new biotech startup aims to delay or reverse disease progression

Lifespan.io (LEAF) - 28-Jan-2022

Tailoring strategies to eliminate bad cells in age-related diseases

Dasatinib plus quercetin combination may help preserve cognitive abilities in elderly people

Lifespan.io (LEAF) - 27-Jan-2022

Senolytics showed positive effects on rats but trials must confirm these findings on human brain

Significant limb regeneration in frogs treated with drug cocktail

The Guardian - 26-Jan-2022

Brief exposure to five factors targeting tissue repair aspects triggers dormant regrowth potential

Cellino Biotech raises $80m to upscale its automated stem cell production

TechCrunch - 25-Jan-2022

Fast, cheap and plentiful iPSCs will be needed for clinical trials and new treatments

LyGenesis published new research showing new options for ectopic liver regeneration

Longevity Technology - 25-Jan-2022

Could lead to alternative to whole-organ liver transplantation

Daily supplementation with urolithin A helps treat muscle fatigue

Medical News Today - 25-Jan-2022

Boosts mitrochondrial health & muscle activity in aged people and those who don't exercise enough

New ageing theory: lake trout fish grow older but don't age

CTV News - 23-Jan-2022

With age, these fish get bigger and more reproductive capable with only minimal risk of death

New study unveils the role of tau in neurodegenerative disease

Buck Institute - 20-Jan-2022

Interactions with mitochondrial & synaptic proteins highlight targets against Tau-mediated disease

Altos Labs comes out of stealth with $3 billion of capital

Genetic Engineering & Biotechnology News (GEN) - 19-Jan-2022

Huge backing that cellular reprogramming can have a significant impact on health and ageing

StarkAge receives 2 million euros to design safer senescence-targeted therapies

Longevity Technology - 19-Jan-2022

Funding will ensure the development of a new immunotherapy for age-related diseases

A simple eye checkup can reveal your true age and overall health

CNN - 19-Jan-2022

Predicting death based on the gap between chronological and retinal age

China's population may have peaked last year as birthrate falls

The Guardian - 17-Jan-2022

Government policies have not reversed long-term decline in population growth

DKG profile interview with its own Remus Stanescu, Director of Longevity Financial Advisors

Deep Knowledge Group - 12-Jan-2022

Highlights some nuances when investing in the longevity industry

Genflow IPO listing: the first longevity firm to debut on London Stock Exchange

Longevity Technology - 10-Jan-2022

Seeking funds to develop gene therapies that target ageing in humans and dogs

Biological age of single cells measured with high precision

Medical Xpress - 10-Jan-2022

Epigenetic age of individual cells helps tracking ageing process in various tissue types

Life Biosciences raises funding to develop innovative therapies against ageing biology

Longevity Technology - 06-Jan-2022

Invests $82 million in research platforms, aiming to prevent or reverse age-related diseases

Theranos ceased for fooling investors with a blood-testing device that never worked

BBC - 04-Jan-2022

Founder convicted of wire fraud and sentenced to several years in prison

Kane Tanaka, world's oldest person from Japan celebrates her 119th birthday

Metro - 03-Jan-2022

This supercentenarian is already aiming to live to 120 years

Reason reviews progress in longevity research and treatments from 2021

Fight Aging! - 31-Dec-2021

There is a phenomenal amount of work going on across the spectrum of ageing - something is going to work eventually!

Rejuveron raises $20 million for Endogena to advance treatment for eye diseases

CISION PR Newswire - 31-Dec-2021

Funds to develop regenerative therapies for retinitis pigmentosa and advanced age-related macular degeneration

Senolytics promotes wound healing in the aged but not in young mice

Lifespan.io (LEAF) - 22-Dec-2021

Dasatinib plus quercetin slow down muscle regeneration in young mice

Korify Capital plans to invest $100m in longevity and mental health space

FierceBiotech - 22-Dec-2021

Aiming to invest in 15-20 biotech firms, including Cambrian Biopharma, to target drivers of ageing

Anti-5G products claims to be protective but actually emit harmful radiation

Independent - 18-Dec-2021

Dutch authorities warned the use of these necklaces, bracelets and sleep masks

Anti-aging treatment: New vaccine by Japanese research can make this happen

Japan Times - 16-Dec-2021

New research claims in removing zombie cells behind aging by vaccination

Serum from older adults increased ageing markers and killed brain stem cells in humans

Lifespan.io (LEAF) - 16-Dec-2021

Brain volume and lifestyle can increase difference between chronological and biological age

Procyanidin, a senotherapeutic compound from grape seed extends lifespan in mice

Lifespan.io (LEAF) - 14-Dec-2021

Improved survival via eliminating old cells - potential candidate to slowdown ageing

MyMD Pharmaceuticals begins phase 2 trial of TNF-inhibitor in January 2022

Longevity Technology - 14-Dec-2021

Potential oral treatment to prevent sarcopenia and frailty, and extend healthy lifespan

NewLimit, a new biotech launches to slowdown or reverse ageing

NewLimit - 12-Dec-2021

Aims to extend healthspan and cure ageing with affordable epigenetic therapies

Spring discovery to prevent diseases by developing treatments for ageing

Medium - 11-Dec-2021

Raised $18 million Series A funding to speed up ageing research

Katcher's Elixir update - 2nd control rat dies, TNF-alpha and IL-6 improvement persists

Live Forever Club - 10-Dec-2021

Rejuvenation continues after 4th dose - will be very interesting to see if max lifespan increases

Quant Biomarkers established to develop sophisticated analytical products

Quant Biomarkers - 10-Dec-2021

DKG subsidiary to introduce biomarker-driven Longevity risk mitigation and intervention support

New Zealand plans to ban cigarettes and become smoke-free by 2025

BBC - 09-Dec-2021

Reducing nicotine addiction in youth by restricting access to tobacco products

Anti-inflammatory exercise factors target cerebrovasculature

Stanford School of Medicine - 08-Dec-2021

Exercise plasma boosts memory and dampens brain inflammation

Valuable insight into the influence of age-associated humoral factors

Genetic Engineering & Biotechnology News (GEN) - 07-Dec-2021

An injection of extracellular vesicles improve muscle regeneration

Virtual Incision's MIRA robotic system successfully performed world's first laparoscopic surgery

FierceBiotech - 01-Dec-2021

Raised $46 million to commercialize and advance robot-assisted surgical technology

Apollo Health Ventures raised $180M fund to invest in longevity innovations

Endpoints News - 01-Dec-2021

Invests in early stage companies that target root causes of age-related diseases

Longevica plans to launch open source platform in 2022, accelerating longevity research

Longevity Technology - 25-Nov-2021

Raised $2.5 million to discover and sell life extension products directly to consumers

Improving mitochondrial function enhances colour vision in old age

New Atlas - 24-Nov-2021

Long wavelength exposure partially restores ATP and improves eye function

Three minute exposure to deep red light can improve your eyesight

University College London (UCL) - 24-Nov-2021

Morning exposure to long wave deep red light showed 17%-20% improvement in colour vision

New study where biological age reduces as chronological age increases

Bioviva Science - 18-Nov-2021

Evident reversal of Dementia symptoms sustained cognitive improvement

Interactive and comparative study of diet and drugs on the hepatic proteome

The University of Sydney - 15-Nov-2021

Dietary composition has a powerful impact on mitochondrial function

New study reversed paralysis and repaired spinal cord injuries in mice

Science Focus - 12-Nov-2021

For decades, a major challenge for scientists is central nervous system.

AMBAR study improved the quality of life in Alzheimer's disease

Lifespan.io (LEAF) - 12-Nov-2021

A hot topic in longevity research is plasma exchange for Alzheimer’s disease

Covid-19 impact lead to reduction in life expectancy and mental wellbeing

Independent - 11-Nov-2021

Cases of anxiety and depression are now doubled when compared to pre-pandemic

Rockfish that lives more than 200 years unveiled genes for longevity

Scientific American - 11-Nov-2021

Insights on longer-living species could offer the targets for extending lifespan in humans

A new model enter into telomere-mediated senescence to reduce genome damage

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2021

Telomeres repair can prevent senescence and genome instability

Whole genome sequencing: a breakthrough approach to diagnose rare diseases

Guardian - 10-Nov-2021

Screening people at risk of genetic diseases thereby reducing the burden of health care costs

Gene-editing technology, CRISPR, selectively kills drug-resistant superbugs

Deutsche Welle (DW) - 10-Nov-2021

A single dose of CRISPR Cas system cleared 99.9% of harmful bacterial in mice

A tiny Greek island with exceptionally long-lived people

NEO.LIFE - 04-Nov-2021

Besides geology, scientists believe multifactorial hormesis contributed to longevity benefits

SENISCA targets sensescence using a new ageing hallmark - dysregulated mRNA processing

Lifespan.io (LEAF) - 03-Nov-2021

Lorna Harries believes dysregulated splicing as a breakthrough senotherapeutic target

University of Leicester proves feasibility of antibody based targeted senolytics

IFL Science - 28-Oct-2021

New study results show clinical applications in pathological ageing

Real, live human skin for testing safety and efficacy of cosmetic treatments

Longevity Technology - 28-Oct-2021

Eric Merle details Genoskin's technology and its applications in anti-ageing trials

A proactive step for next generation drug discovery by Cambrian Biopharma

Longevity Technology - 26-Oct-2021

Novel business approach helps people to live longer with good health

23andMe acquired virtual healthcare firm Lemonaid Health for $400M

pharmaphorum - 25-Oct-2021

Merger to improve remote health services and offer personalised treatment plans

Mitlets improve immunity and treat many age-related diseases

Longevity Technology - 22-Oct-2021

Experimental therapy to transfuse healthy mitochondria from multiple donors

Turning off abnormal genes may cure crippling genetic disease

BBC - 21-Oct-2021

Potential gene silencing approach in porphyria and possibly for many other diseases in the future

New study finds normal blood pressure can keep your brain younger

Big Think - 20-Oct-2021

Increased blood pressure was linked to dementia and older-looking brains

New study leading towards permanent youthful immune function

Lifespan.io (LEAF) - 18-Oct-2021

Significant alteration in lineage potential by NR treatment in mice

Biobank study: People with longer telomeres live 2.5 years longer

Lifespan.io (LEAF) - 13-Oct-2021

New insights into the genetic regulation of leukocyte telomere length

Longevity gap differs greatly between the rich and poor areas of England

BBC - 13-Oct-2021

Report finds alarming fall in life expectancy even before COVID pandemic - calls for better policies

Stem cells spotted leaking out of follicle in possible cause of hair loss

Lifespan.io (LEAF) - 12-Oct-2021

Noninvasive imaging technology used to observe aging on the cellular level

Revel pharmaceuticals restores tissue function using AGE-cleaving enzymes

Longevity Technology - 12-Oct-2021

A unique treatment approach for ageing; will soon begin trials in animals and human cadaver tissue

FDA puts clinical hold on Allogenic CAR T therapy due to safety concerns

FierceBiotech - 08-Oct-2021

Chromosome abnormality reported in a clinical trial raises doubts on patient safety

$100m Longevity Co-Investment Fund (LCIF) launched by Maximon in Switzerland

Longevity Technology - 07-Oct-2021

Plans to invest in 10 start-ups - any of which could make a step towards longevity escape velocity

Senolytic drugs improved survival rates in coronavirus-infected mice

SENS Research Foundation - 07-Oct-2021

Boosts immune response by clearing senescent cells; a potential treatment for COVID-19 in humans

Mammalian brain cells mapped for better understanding of the neuronal disorders

EurekAlert! - 06-Oct-2021

The atlas of the brain cells developed will help pave the way for future research in brain disorders

Longevity Science Foundation to fund $1 billion for a 120-year human lifespan

Longevity Technology - 30-Sep-2021

The foundation's mission is to make longevity medicine accessible to everyone - fantastic news!

Blind mole rats use junk DNA to trigger self-destruction of cancer cells

The Scientist - 30-Sep-2021

Retrotransposons activate immune response against precancerous cells - may have implications in humans

Calorie restriction slows age-related stem cell exhaustion, improving overall health

Lifespan.io (LEAF) - 29-Sep-2021

Many studies underlined beneficial effects of calorie restriction in various tissues of mice

Start-ups to scale manufacturing of stem-cell therapies for practical use

Nature - 29-Sep-2021

Challenges of mass producing stem cells and how 3 companies are attempting to overcome them

The Rejuvenome project plans to combine multiple anti-ageing interventions in mice

Fight Aging! - 27-Sep-2021

One drug doesn't fit all; combination therapies to address multiple ageing processes at once

New supercooling technique preserved human heart tissue from damage

Medical Xpress - 27-Sep-2021

Retains structural and functional effects even after preserving at subzero temperatures

Smart toilets could provide effortless monitoring of a range of biomarkers, not just gut health

Guardian - 23-Sep-2021

Coprata and Toi Labs among companies looking to bring products to market in the next couple of years

Reversible reprogramming regenerates cardiac tissue after a heart attack

Endpoints News - 23-Sep-2021

Possibility of regeneration: A boon to the broad rejuvenation field

Loyal aims for a animal pharmaceutical company to delay ageing of "man's best friend"

TechCrunch - 23-Sep-2021

Developing therapies to extend life in dogs, and further extending the research in humans

Covid-19 hit hardest in men, cutting their life expectancy by over an year

BBC - 23-Sep-2021

Life expectancy will recover in the future, but with a 'slower growth'

Underdog pharmaceuticals secures $10m funding from Kizoo ventures

Longevity Technology - 23-Sep-2021

Funds to bring affordable and effective age-related therapies to the public

WHO rewrites air quality guidelines, slashing safe limit for pollutants from fossil fuels by 50%

Guardian - 22-Sep-2021

A step towards breathing harmless air amidst rising evidence of deadly harm from air pollution

Living near nature can slow down biological ageing process in women

SciTechDaily - 22-Sep-2021

GrimAge finds link between greenery and reversal of DNA methylation & other health benefits

A new nanoreactor repaired the damaged region in cells by supplying ATP

Singularity Hub - 21-Sep-2021

Energy generation in living cells by programmed exosome fusion

Senolytic cocktail reduces age-related spinal disc degeneration in mice

Lifespan.io (LEAF) - 21-Sep-2021

Dasatinib and quercetin combo preserves spinal discs to target age-related back pain

Baby shortage in the country may lead to long-term economic stagnation

Guardian - 20-Sep-2021

Worldwide 28% of countries adopt pronatalist policies to drive up the birthrate

Ex-wife was accused of stealing frozen bodies - possibly for revenge

Newsweek - 17-Sep-2021

Cryopreservation protects the dead body from decomposition process after death.

A single protein reversed senescence in skeletal muscle cells

University at Buffalo - 17-Sep-2021

NANOG targets multiple ageing mechanisms - insights may help develop new therapies for age-related disorders

Elevian has secured $40 million for anti-aging diseases and heart stroke

FierceBiotech - 17-Sep-2021

$40 million for clinical research, lead program-stroke recovery focuses GDF11

OMEGA, a new powerful gene-editing system similar to CRISPR or so much better

New Atlas - 16-Sep-2021

Potential RNA-guiding enzymes that are capable of editing and modifying DNA in human cells

Fewer mistakes in protein synthesis extends lifespan in simple microbes

Phys.org - 14-Sep-2021

Interestingly, rapamycin (and other drugs) also improves accuracy of protein production

Polygenic risk of age related diseases effect on human lifespan

GenomeWeb - 14-Sep-2021

Rare variants in non-coding RNAs are connected to various neurological disorders

New biological ageing clock based on movement data from a wearable device

Lifespan.io (LEAF) - 14-Sep-2021

Tracks biological age from physical activity without requiring a blood test

A promising approach to rejuvenate aged mesenchymal cells by chromatin

Medical Xpress - 13-Sep-2021

Short-term treatment of mesenchymal cells with acetate resulted to enhanced stem cell

Role of mature dendritic cells in thymic involution

Lifespan.io (LEAF) - 13-Sep-2021

Reversal of thymic aging possible through signaling based interventions

Centaura's human artificial chromosome to treat complex diseases, including ageing

Medium - 10-Sep-2021

A breakthrough technology focusing on effective gene therapies for healthy longevity

Short term exposure to particulate matter cause specific mortality

The Conversation (UK) - 08-Sep-2021

Exposure reduction targets aim to lower air pollution levels

Owlstone Medical raised $58M to advance its breath biopsy technology

FierceBiotech - 07-Sep-2021

Developing painless tests to detect lung cancer, liver diseases, respiratory diseases, and gut health

Complicated connection between protein shape and mitochondrial health, causing aging

Buck Institute - 07-Sep-2021

The “bad” process of pore opening and the “good” process of UPRmt - connection revealed

New CRISPR based stem cell implant releases drug as required in arthritis

GEN News - 02-Sep-2021

Reduced inflammation & bone damage in mice; relieves patients from their regular use of injections

Laronde is creating safer and effective 'Endless RNA' therapies

Chemical & Engineering News (C&EN) - 30-Aug-2021

Raised $440m to advance e-RNA based medicine for a wide range of diseases

DunedinPACE, a highly precise new generation epigenetic ageing clock

Lifespan.io (LEAF) - 27-Aug-2021

Tracks rate of ageing and predicts onset of disease or death with a single blood test

Fauna Bio finds new avenues for drug discovery through animal genomics

Longevity Technology - 27-Aug-2021

By investigating self-healing mechanisms in animals, Fauna bio aims to cure human diseases.

Longest-lived bats unveiled secrets to longer and healthier lives

Medical Xpress - 26-Aug-2021

Novel genes increase DNA repair and limit damage to slow down ageing process

Illegal yohimbine and synephrine pills found online without health warning labels

Guardian - 25-Aug-2021

Products promising weight loss are for sale on internet; users may face health complications

Summary of Eric Verdin presentation at End Age-Related Diseases 2021

Live Forever Club - 21-Aug-2021

Discusses causes and prevention of NAD depletion with a focus on CD38 consumption

Ubiquitination of cell proteins determines ageing and longevity in C. elegans

SciTechDaily - 21-Aug-2021

Levels of ubiquitin-tagged proteins affect lifespan - insights may find answers to longevity

Summary of Irina Conboy presentation at End Age-Related Diseases 2021

Live Forever Club - 20-Aug-2021

Very much looking forward to seeing published results on initial human pilot

Tiny lab-grown human brain clusters develop functional eyes that sense light

Ophthalmology Times - 20-Aug-2021

A promising approach to restore eyesight in visually impaired people

Safer and faster treatment of tendon injuries with stem-cell fat grafts

Genetic Engineering & Biotechnology News (GEN) - 17-Aug-2021

Tendons regain their original healthy condition within 2 months of therapy in sheep

SIRT6 variant plays a major role in preventing the aging process

Longevity Technology - 17-Aug-2021

Novel gene therapies to prevent the accelerated aging process

A new perifollicular microenvironment for androgenetic alopecia treatment

New Atlas - 16-Aug-2021

Accelerated hair regeneration in the androgenetic alopecia mouse model

Scientists uncover patterns of metabolism in humans across the life course

BBC - 13-Aug-2021

Metabolism remained same throughout the mid-life and starts to decline only at 60 years

Hyperactivation of senescent cells can trigger cytokine storm

Lifespan.io (LEAF) - 13-Aug-2021

Stimulated senescent human umbilical vein cells showed high susceptibility to inflammatory diseases

Astrocytes target white matter stroke and other neurodegenerative diseases

Medical Xpress - 12-Aug-2021

Reliable and safe generation of a novel stem cell-based therapy for dementia

Skeletal stem cells delay bone healing and foster inflammageing in older people

Medical Xpress - 12-Aug-2021

Treating with BMP2 and Csf1 antagonist in mice restored youthfulness to the aged skeletal system

Scientists activate stress response pathway to keep cultured stem cells healthy

University of California, San Diego (UCSD) - 12-Aug-2021

Improvement seen in blood stem cells of mice and humans against stress and ageing

Penetrable sunscreen agents could reverse skin damage and ageing

SciTechDaily - 12-Aug-2021

Two novel compounds fuel mitochondria to maintain energy balance and lower UV damage in the skin

Extracellular matrix gene expression: a novel approach to find geroprotective drugs

Lifespan.io (LEAF) - 11-Aug-2021

ECM reprogramming to identify drugs which can slow-down or prevent age-related diseases

Liver-fat content and bodyweight reduction with effective use of CB4211

GlobeNewswire - 10-Aug-2021

Mitochondrial genome used to potentially treat fatty liver and prevent obesity

New study links height loss and age-related cardiac deaths

Guardian - 09-Aug-2021

Get the measuring tape out, here's another biomarker to track!

Implantable cell pouches as living medicines to treat chronic diseases

MedCity News - 09-Aug-2021

Encellin's encapsulation device protects implanted cells, promising targeted cell therapy

Frailty in old mice disappears with small extracellular vesicles from young mice stem cells

Fight Aging! - 09-Aug-2021

Molecular level benefits observed (inflammation, senescence) as well as physical ones

Gut microbes show potential to reverse aging-related deterioration in brain

University College Cork - 09-Aug-2021

Microbiome in the gut could potentially slow down brain aging and improve cognitive functions

A Sardinian village, Perdasdefogu celebrates and honours its centenarians

Guardian - 08-Aug-2021

Local centenarians share the secret to longevity: good food, active lifestyle, and sociality

Longevity Technology interviews Aubrey de Grey about senolytics and other senotherapeutics

Longevity Technology - 05-Aug-2021

Most approaches have their limitations but good progress is being made on several fronts

Role of muscle strengthening protein in reducing life span

Johns Hopkins School of Medicine - 04-Aug-2021

Activation of CaMKII improved muscle fitness but increased the risk of ageing

Despite nutrient reformulation targets, most companies sell unhealthy foods

Nuffield Department of Population Health - 04-Aug-2021

Food firms in UK failed to meet targets for reducing calories, sugar and salt in their products

Deep Longevity's epigenetic aging clock, DeepMAge, retrained to use saliva samples

Longevity Technology - 02-Aug-2021

With an accuracy of 4.7 years it is much more convenient for home testing

Scientists uncover mechanism that promotes ageing in mammalian stem cells

Medical Xpress - 02-Aug-2021

Evidence of cryptic transcription in older cells offers new strategies for longevity

Pulse oximeters can give false readings in people with dark skin tone

Independent - 31-Jul-2021

NHS suggests to take multiple readings to detect the drop in oxygen levels

Unique gut bacteria linked to healthy ageing in centenarians

Live Science - 30-Jul-2021

Fuels bile acids to prevent infections, but more research is needed to confirm its impact on longevity

Scientists find dormant regenerative abilities of the inner ear in mice

SciTechDaily - 30-Jul-2021

Advanced gene therapies can reactivate hair cells, which are vital for hearing

Lifespan.io interviews George Church about gene therapy and longevity

Lifespan.io (LEAF) - 28-Jul-2021

Discusses animal trials, potential human trials, reeducating the FDA and improvements in technology

AbbVie and Calico extends their collab up to 2025 with a $1 billion deal

FierceBiotech - 27-Jul-2021

Supports ageing research and advancing early-stage projects to phase 2 trials over the next decade

Experimental national estimates of life expectancy and mortality based on ethnicity

Guardian - 26-Jul-2021

Compared to blacks and Asians, whites and mixed groups had lower life expectancy

Levels of fatty acids in blood predict death in older people

Lifespan.io (LEAF) - 26-Jul-2021

Myristic acid, benehic acid, and omega 3 increase lifespan; palmitoleic acid lowers lifespan

Being wealthy at midlife may give you a longer and healthier life

Northwestern University - 23-Jul-2021

Lifespan differences exist even between rich and poor siblings/twins

Activation of telomerase gene prevents aging in certain types of cells

EurekAlert! - 23-Jul-2021

DNA region: VNTR2-1 plays a role in human aging and tumorigenesis

Merger between regeneration companies AgeX and LyGenesis not going ahead

Business Wire - 23-Jul-2021

Both companies to continue with the diverse technologies and product development

Leeds city council set to raise awareness against use of wood burning stoves

Leeds Live - 22-Jul-2021

New action plan to reduce air pollution and improve people's lives

Scientists invent AI that predicts potential lifespan-extending compounds

Phys.org - 22-Jul-2021

Anti-ageing probability validated from a worm with human-like metabolism

US life expectancy dropped by 1.5 years in 2020, mostly due to COVID-19

Independent - 21-Jul-2021

Largest drop since world war II, mainly affecting Black and Hispanic Americans

Galapagos giant tortoises kill damaged cells to resist cancer and ageing

New Scientist - 20-Jul-2021

Large, long living animals offer insights on natural ways of cancer resistance

Latest AI tool predicts proteins structures in just 10 minutes

SciTechDaily - 17-Jul-2021

Freely accessible software from GitHub to help scientists speedup their research process

Dr. Matt Kaeberlein argues for more funding for geroscience

The Hill - 16-Jul-2021

Chair of American Aging Association disappointed ARPA-H may only receive half the requested funding

Treatments that delay ageing could be worth trillions of dollars to the US alone

World Economic Forum - 15-Jul-2021

As more people live longer (lifespan) it is essential that their health keeps up too (healthspan)

Immune system clock tracks health, age-related disorders, and longevity

Buck Institute - 12-Jul-2021

Measuring immune health with a chemokine, CXCL9, for early disease interventions

Liberum's automated system manufactures proteins from DNA within hours

University of Toronto - 08-Jul-2021

Nespresso for protein production: prototype inspired from single-serve coffee makers

Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

Elamipretide: a drug to protect your eyes from AMD

Ophthalmology Times - 07-Jul-2021

Elamipritide protects your retinal cells from undergoing degeneration

Pro-repair microenvironment after injury is favored by targeting senescent cells

News Medical - 06-Jul-2021

Senolytic drugs administration promotes locomotor and sensory recovery

Castration leads to longer life in male sheep, mediated by low androgens

EurekAlert! - 06-Jul-2021

There may be less men queuing up for this first generation longevity treatment!

Unity's senolytic drug reports positive phase 1 data in eye disease patients

FierceBiotech - 06-Jul-2021

Begun phase 2 trial including patients with early stage of disease to test its safety and effectiveness

Lonely older people are living shorter with poorer health, finds new study

EurekAlert! - 06-Jul-2021

Covid preventive measures seem to further exacerbate the risk of loneliness

Unique adaptations contribute to the longevity of American lobster

Medium - 04-Jul-2021

Insights on longevity, neural, and immune adaptations are revealed by a lobster

Longenesis closes $1.2 million to speed up digitisation of biomedical research

Longevity Technology - 02-Jul-2021

Latvian based startup aims for cost-effective research studies, prioritizing study participants

Long-term caloric restriction prevents age-related adiposity in aged mice

Lifespan.io (LEAF) - 02-Jul-2021

Targeting SA-T cells: A promising intervention to control age-related chronic diseases

DNAm GrimAge is a strong predictor of mortality independent of genetic influences

Fight Aging! - 30-Jun-2021

Twin study allowed impact of lifestyle factors on epigenetic aging to be determined

Health inequalities widen life expectancy gap between rich and poor in England

Guardian - 30-Jun-2021

High death rate in poorer areas, post-covid levelling up must prioritize health equity

Zoledronate - accidental discovery of drug use for life extension

Lifespan.io (LEAF) - 30-Jun-2021

Too early to tell whether off-patent drug's effects in fruit flies will be seen in humans

Lifespan.io interviews Dr. Nir Barzilai about metformin, longevity genes and more

Lifespan.io (LEAF) - 29-Jun-2021

Optimistic on ageing research and a breakthrough human trial to extend healthspan

New CRISPR gene-editing drug for a rare protein-misfolding disorder

pharmaphorum - 28-Jun-2021

Phase 1 trial reports, single dose of the drug cuts protein levels by 87% in ATTR amyloidosis

Eating less than 800 calories a day favoured weight loss via hungry pathogens

ScienceAlert - 27-Jun-2021

Long-term safety of the diet is questionable as it alters the healthy gut microbiome

Nick Engerer interviews Gordan Lauc about the science behind GlycanAge's biological age test

Longevity blog - 27-Jun-2021

The glycome changes with age - and is measurably affected by lifestyle choices

Embryos reset biological age back to zero in early stage of development

Science News - 25-Jun-2021

Rejuvenation process in germline cells may help find new therapies for age-related disorders

Antibiotics extended the lives of the flies and changed their gene activity

Phys.org - 24-Jun-2021

In future, we can locate the genes which are linked to the aging process

One test for all infectious diseases: rapid diagnosis with Torus Biosystems

Medgadget - 24-Jun-2021

Synestia system, a point-of-care device to detect any pathogen in less than 30 minutes

Tryptophan-deficient diet alters gut microbiome, causing unhealthy ageing

Augusta University - 24-Jun-2021

Reduced beneficial gut bacteria and increased systemic inflammation in aged mice

Therapeutic plasma exchange can have almost immediate benefit

NEO.LIFE - 24-Jun-2021

Lou Hawthorne, CEO of NaNotics, provides his account of TPE and feeling younger

Youthful stem cells delayed ageing through their secretions in mice

Lifespan.io (LEAF) - 23-Jun-2021

Potential stem cell treatment for age-related diseases, if succeded in human trials

US life expectancy records biggest fall due to covid pandemic

Guardian - 23-Jun-2021

Health inequalities mainly affected life expectancy of minority groups

Psychosocial stress levels are linked with hair greying and reversal

Scientific American - 22-Jun-2021

Human hair greying dynamics is associated with biobehavioral factors

Insilico raises $255M to advance human trials and AI drug discovery platform

Longevity Technology - 22-Jun-2021

New collab with Teva Pharmaceuticals to identify drug targets for various diseases

Returning function to paralysed upper limbs is the primary goal of Orthocell trial

The Market Herald - 21-Jun-2021

Peripheral nerve repair could benefit 3 million patients every year

Senescent immune system is a therapeutic target to extend healthy ageing

WVU Today - 21-Jun-2021

Degraded DNA repair in immune cells can cause premature ageing in the whole body

Ochre Bio secures $9.6M funding for development of RNA therapies

Business Wire - 16-Jun-2021

Convergence of genomic technologies and machine learning digitizes liver biology

Stem cell therapy: A potential avenue for reversing pituitary gland ageing

Medical Xpress - 15-Jun-2021

Slowing down natural ageing process of pituitary glands with stem cells

A 12-week strength-endurance training lowered senescence proteins in older people

Lifespan.io (LEAF) - 14-Jun-2021

New study using biomarkers proved the importance of regular exercise again

Brinter raises €1.2M fund for producing human spare parts and customised drugs

Longevity Technology - 11-Jun-2021

Printing brains and transplantable organs to save and improve lives

Restoration of youthful gene expression can be achieved alternatively

Lifespan.io (LEAF) - 11-Jun-2021

Possible ways of using reprogramming techniques to develop therapies

Lab-grown human liver tissue functioning for 30 days

Space - 10-Jun-2021

we'll gain the knowledge to keep astronauts healthy as they journey further into space

Babylon to become a public company via $4.2bn merger with Alkuri Global

Digital Health - 08-Jun-2021

Funds to help this digital health company take a leap in offering quality healthcare

Catalysis of TET1 - necessary for myelin repair in young adults

Genetic Engineering & Biotechnology News (GEN) - 08-Jun-2021

Regulation of adult remyelination in mice by TET1-mediated DNA hydroxymethylation

DNA-damage or telomere shortening may not cause normal ageing

EurekAlert! - 08-Jun-2021

Rapamycin fails to extend lifespan in telomerase-deficient mice, while improving lifespan by 39% in normal mice

Science predicts that theoretically we can live up to 150 years

The Conversation (UK) - 08-Jun-2021

Is it time to find ways to make it our average life expectancy?

Geography affects gut microbiome in healthspan and longevity

Fight Aging! - 07-Jun-2021

One treatment does not fit all - diversified gut microbiota needs customizable medicine

Tiny worms in Siberian permafrost can reproduce even after 24,000 years

Guardian - 07-Jun-2021

Survival abilities of rotifers may help scientists develop better cryo-preservation techniques

Aging clock predicting the effect of longevity interventions

Lifespan.io (LEAF) - 03-Jun-2021

Transcriptomic aging clock: providing insight into the changes involved in aging

Patients with Type 2 diabetes are treated with their bone marrow stem cell

EurekAlert! - 03-Jun-2021

Need for stem cell intervention for patients diagnosed with T2DM

Injecting new mitochondria to replace old, damaged mitochondrial DNA in humans

Lifespan.io (LEAF) - 02-Jun-2021

Potential treatment for mitochondrial diseases & dysfunction, and extends lifespan

BioAesthetics' NAC graft reconstructs a real, living nipple after breast surgery

Medical Expo - 02-Jun-2021

Allows patient's own cells to rebuild the nipple and areola - currently under clinical trials

SIRT6 restores energy in older mice, increasing lifespan by 30%

ISRAEL21c - 01-Jun-2021

Overexpression of this protein delays frailty and overcomes age-related diseases

Playing certain sports can help you live 13% longer than the general population

Medical Xpress - 01-Jun-2021

Cricket, rugby, tennis and golf players lived longer; footballers, boxers and jockeys had shorter lives

Excessive alcohol consumption makes women age faster

Lifespan.io (LEAF) - 31-May-2021

GrimAge clock presented accurate results on biological age than other epigenetic clocks

Oisín raised $9.5M to advance senolytic therapies for kidney & age-related diseases

Longevity Technology - 28-May-2021

Investigational therapy on old mice cleared senescent cells up to 70%, extending life by 20%

Recharge your mitochondrial batteries to live longer

Longevity Technology - 27-May-2021

Breakthrough in longevity research - cellular energetics may stop or even reverse the ageing process

Amazonian tribe with healthier brains reveal basics of healthy ageing

USC news - 26-May-2021

Healthy diet and lifestyle of Tsimane slowed brain atrophy, lowering the risk of Alzheimer's & dementia

Blood cells and footsteps count predict the maximum human lifespan

Scientific American - 25-May-2021

A natural limit of 120-150 is a good start before even starting rejuvenation therapies

Brain can learn to see again using algae proteins

BBC - 24-May-2021

Optogenetics bring back vision partially with light sensing proteins - new hope for the blind

Sesame-sized heart organoid beats just like a human heart

ScienceAlert - 23-May-2021

Planning to grow multi-chambered heart, to advance cardiovascular therapies in the future

mTOR inhibitors reversed immune ageing to treat viral infections in older adults

Lifespan.io (LEAF) - 21-May-2021

Much needed approach to improve immune function during the COVID pandemic

Biohacker Ari Rastegar is only 5 years old biologically

New York Post - 20-May-2021

Stem cell therapies, meditation in hyperbaric chamber are few of his extreme health practices

RepliCel contracts Accerise to plan phase 2 cell therapy trials in Japan

Biospace - 19-May-2021

Successful trial results could bring us skin rejuvenation & tendon regeneration products

Light therapy can restore healthy and youthful skin

Photonics Media - 19-May-2021

Low-level LED light improves wound healing and is a promising therapy for skin rejuvenation

Tapeworm infestation flash-freezes ants, helping them stay young and live longer

The Atlantic - 19-May-2021

Infected ants lounge in the nest, living as long as their colonies' queen

Achilles raised $175.5 million to develop new cancer immunotherapies

Cancer Research UK - 18-May-2021

Patient-specific cell therapies under clinical trials for treating lung cancer and melanoma

NR supplementation restored youthfulness to blood in older mice

Lifespan.io (LEAF) - 18-May-2021

Lowers age-related defects of blood stem cells & make stem cell transplants more effective

SIRT6 overexpression delays ageing of heart cells in mice

Lifespan.io (LEAF) - 17-May-2021

Anti-ageing therapies targeting sirtuins may slow down multiple effects of human ageing

Lifespan.io crowd-funds clinical trial to determine the effects of Rapamycin

Lifespan.io (LEAF) - 17-May-2021

PEARL: Participatory Evaluation of Aging with Rapamycin for Longevity

A snailfish modified its DNA for survival in the deep ocean

New Scientist - 13-May-2021

Yap hadal snailfish made extra genes to repair DNA & stay alive in high-pressure deep-sea waters

FDA grants Endogena's primary program for EA-2353 suspension targeting retinitis pigmentosa

Biospace - 13-May-2021

Endogena’s photoreceptor regeneration approach offers new treatment paradigm in retinitis pigmentosa

Natural compound may help treat intervertebral disc degeneration

Lifespan.io (LEAF) - 12-May-2021

DHE slowed senescence in intervertebral discs of mice; but its use in anti-aging is still questionable

Folds in mitochondria membrane are lost as we age - reducing production of ATP

I Spy Physiology - 12-May-2021

Antioxidant treatment reversed mitochondrial ageing via cardiolipin in mice

New gene therapy technique, CopyCatcher, more accurate in fruit flies

SciTechDaily - 11-May-2021

Targets precise location of mutated gene rather than tagging on anywhere

Men (and, strangely, only men) in physical jobs live longer than their peers

Fight Aging! - 11-May-2021

Physically active work life and better lifestyle choices linked to long-term survival in men

Gene therapy preserved memory and learning in mice with Alzheimer's

Lifespan.io (LEAF) - 11-May-2021

Boosting a vital protein, Caveolin-1, this new technique offers hope against neurodegenerative diseases

Medicine by Design invests $3M to tackle regenerative medicine's grand questions

University of Toronto - 10-May-2021

Funding four bold projects to improve health care outcomes for degenerative diseases

New immunotherapy clears out senescent cells to combat aging

Medical Xpress - 10-May-2021

Activated immune cells can treat age-related chronic diseases - a potential alternative to senolytics

Michael Greve promises 300m euros to advance rejuvenation startups

Longevity Technology - 06-May-2021

Kizoo Technology Ventures helps to bring rejuvenation therapies from lab to clinic

Bigmouth buffalo fish can live up to 112 years with no signs of ageing

Lifespan.io (LEAF) - 06-May-2021

Long-living fish gives key insights on evolution history to age slower and live longer

Low magnitude vibration to prevent/delay age-related bone loss in rats

Lifespan.io (LEAF) - 05-May-2021

Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissues

Youthful gut microbiome rejuvenates ageing immune system

Fight Aging! - 05-May-2021

Restoring gut microbial health can reverse declining age-related immune fitness

FOXO licenses use of epigenetic clocks in life insurance industry

Longevity Technology - 05-May-2021

Modernizing life insurance to keep its customers healthy and alive

BioViva tests experimental telomerase gene-therapy in 6 Alzheimer's patients

Biospace - 03-May-2021

Launched home test to track biological age; outcomes of unlicensed gene-therapy are yet to report

Raising awareness on senolytic drugs as a promising anti-ageing medicine

Longevity Technology - 30-Apr-2021

Senolytic Therapy Network aims to take the senotherapeutics from lab to clinic

Longevity Technology interviews Irina Conboy about blood plasma exchange

Longevity Technology - 29-Apr-2021

"Very promising" results from pilot study, with phase 3 clinical trial planned

Food odour nullifies lifespan benefits of dietary restriction in nematodes

Lifespan.io (LEAF) - 29-Apr-2021

You may have to avoid smelling, not just eating, food for CR to be effective

Inherited blindness can now be cured with gene therapy

BBC - 29-Apr-2021

A breakthrough gene therapy restores eyesight in patients with rare eye disease

Intermittent fasting improves gut health to lower high blood pressure

Baylor College of Medicine - 29-Apr-2021

Correcting gut dysbiosis alters bile acid levels & may help manage hypertension in rats

Bioage licenses new drugs to treat ageing and age-related diseases

Lifespan.io (LEAF) - 28-Apr-2021

Raised $90M in series C funding - off to a great start initiating three clinical trials

Longevica to launch life extension supplements by late 2021

TechCrunch - 23-Apr-2021

A 11-year long research in mice revealed 5 potential compounds to increase human longevity

Light-sensing cones from human stem cells restored vision in mice

The Scientist - 23-Apr-2021

Will be looking to run a human clinical trial in the next few years

One-time stem cell therapy activates brain's self-repair process

Drug Target Review - 22-Apr-2021

Cell therapy repairs brain damage from dementia and stroke in mice, soon to begin human trials

Atomic structure of human telomerase developed using cryo-electron microscopy

Phys.org - 22-Apr-2021

High resolution telomerase model revealed new protein subunits; promises new therapy for aging diseases

Latest technology to cryo-preserve organs for future use

IEEE Spectrum - 21-Apr-2021

Beyond organs, researchers found a way to restore ecosystem and possibly a fauna ark on the moon

Klotho protein reversed muscle ageing in old, but not older mice

eLife Sciences - 20-Apr-2021

Potential future treatment strategy to prevent sarcopenia when supplemented at a young age

Genes correlated for diseases with similar age at onset

Medical Xpress - 19-Apr-2021

UK Biobank study reveals genetic links & potential treatment strategies for age-related diseases

Diet and lifestyle changes reversed epigenetic ageing in males

Lifespan.io (LEAF) - 19-Apr-2021

Dietary, exercise, sleep, supplements, and breathing regimen for 8 weeks reduced epigenetic age by 2 years.

Right amount of lab-grown retinal cells can cure glaucoma

Moscow Institute of Physics and Technology (MIPT) - 19-Apr-2021

For the first time, cultured retinal cells transplanted & survived in the eyes of mice for a year

Brain cells reprogrammed to neurons within the brain of mice

Lifespan.io (LEAF) - 13-Apr-2021

In vivo conversion of astrocytes could possibly bring brain regeneration therapies in the near future

Dog Aging Project invites participants to study canine health and longevity

University of Washington - 13-Apr-2021

Understanding the impact of genes, lifestyle, and environment on ageing

Reactivating neural stem cells helps fight brain ageing

EurekAlert! - 12-Apr-2021

Abl1 gene as a potential drug target improved stem cell rejuvenation in aged mice

Sugary drinks tax will help reduce overweight and obesity

Nuffield Department of Population Health - 10-Apr-2021

UK's soft drinks levy encourages both manufacturers and consumers for low sugar alternatives

Latest CRISPR editing method can turn on/off gene expression

Phys.org - 09-Apr-2021

Allows to silence bad genes without modifying the DNA sequence and it is fully reversible

A natural compound reverses skin wrinkles and hair loss in mice

Longevity Technology - 08-Apr-2021

Targets mitochondrial dysfunction - cosmeceuticals on its way to reverse ageing signs in humans

Could diluting blood with recombinant serum albumin reverse ageing?

Fight Aging! - 06-Apr-2021

Disappointingly, no impact was observed on maximum lifespan - still looking for the next bridge

SenNet: a new NIH initiative to fight ageing

Lifespan.io (LEAF) - 06-Apr-2021

Establishing a massive database on cellular senescence to improve human health

Cells in depressed individuals were 2 years older than their real age

University of California, San Francisco (UCSF) - 06-Apr-2021

GrimAge predicts increased cellular ageing & mortality risk in people with major depression

First ever non-invasive biomarker test to detect senolysis

Buck Institute - 02-Apr-2021

Detectible senescence-specific biomarker allows development of new drugs for age-related conditions

'Rogue' protein assists cancer progression in humans

The Scientist - 01-Apr-2021

Inactivating Siglec-XII could lower the risk of cancer, but more research is still needed

2021 NIA's lifespan extension study results on mice out now

Longevity Technology - 01-Apr-2021

Longer lifespan in old male mice treated with 17‐α‐estradiol, but four other compounds had no effect

Gyroscope secures $148M to develop treatment for rare eye diseases

Longevity Technology - 29-Mar-2021

Funds to advance gene therapy for age-related macular degeneration & innovative delivery system

New monoclonal antibody drug regrows lost teeth in ferrets

New Atlas - 29-Mar-2021

Promising tooth development approach for tooth anomalies after successful trials on pigs & dogs

Wild Biotech's unique database maps new targets for human diseases

Longevity Technology - 29-Mar-2021

Huge database of wildlife gut microbiota could screen potential therapies within days

CAR Macrophages for cancer immunotherapy enters phase 1 trial

The Scientist - 26-Mar-2021

Gene modified macrophages may surpass CAR T cells in treating solid tumors

Miscarriage could be an early marker for future health risk in women

Independent - 25-Mar-2021

Recurrent or young age miscarriages can up the risk of dying early, but more studies are needed

A low-calorie diet maintains youthful gut state & improves lifespan

Fight Aging! - 24-Mar-2021

Calorie restriction prevents age-related changes to the gut microbiome in mice

Reprogramming turns aged human cells young again

New York Times - 24-Mar-2021

Stanford University research published in New York Times - age-reversal is no longer fringe science!

Gene modified immune cells prevent cancer metastasis in mice

Medical Xpress - 24-Mar-2021

Signaling distant sites to alert & activate cancer killing immune cells in advance

Life Extension supplement to clear out senescent cells

GlobeNewswire - 23-Mar-2021

New plant-based longevity pill that offers better access to many health benefits

A man-made molecule that helps repair and regenerate muscle tissue

EurekAlert! - 23-Mar-2021

Givinostat induces stem cells to produce muscle making cells - promising therapy for age-related muscle loss

You can have too much of a good thing - including exercise

The Scientist - 23-Mar-2021

2.5 hours of HIIT in a week reduces mitochondrial respiration, meaning less energy for the body

Highest exercise load lead to reduction in intrinsic mitochondrial function

The Scientist - 23-Mar-2021

Substantial mitochondrial respiratory impairment is included with excessive exercise

João Pedro de Magalhães discusses longevity pharmacology and importance of human trials

Longevity Technology - 23-Mar-2021

Advances in longevity pharmacology to revolutionize healthcare with personalized therapies

BioAge's anti-ageing drug to treat Covid-19 enters phase 2 trial

Longevity Technology - 22-Mar-2021

Reverses immune ageing and can prevent death from coronavirus infection in the elderly

Poorest dies almost 20 years younger than rich in England

iNews - 22-Mar-2021

High mortality rate in deprived areas alarms healthcare inequalities

New mechanism underlying baldness and thinning of hair discovered

New Atlas - 18-Mar-2021

Balance in cell divisions control regenerative capabilities of hair follicle stem cells

People may be ageing faster or slower than their actual age

US News - 18-Mar-2021

Genes play a key role, but healthy diet and exercise can help you look and feel younger

CohBar's lead candidate may initiate clinical trials in 2022

Longevity Technology - 16-Mar-2021

Mitochondrial-based therapy enters IND to tackle IPF and other fibrotic diseases

AgomAb raises €62M in Series B round to advance regenerative medicine

Labiotech - 16-Mar-2021

Funds to bring the experimental drug to trials; symbolizes booming regenerative niche

Insitro secures $400 million in series C funding

FierceBiotech - 15-Mar-2021

Giant leap towards developing transformative medicines powered by machine learning

SENISCA secures 1.3 million pounds to transform anti-ageing technology

University of Exeter - 12-Mar-2021

Spin out company from University of Exeter step forward towards precision medicine for age-related diseases

Gene therapy for Alzheimer's disease enters human clinical trial

Forbes - 12-Mar-2021

Virus carries gene encoding protein into the brain -possible breakthrough treatment for neurodegenerative diseases

Canada's largest study of ageing raises $9.6 M infrastructure fund

Simon Fraser University (SFU) - 12-Mar-2021

Federal funding for CLSA advances ageing research, promoting health and well-being of older adults

Maximon builds new longevity companies from scratch

Longevity Technology - 08-Mar-2021

Working on its first two companies at the moment, aiming at global expansion in the coming years

Single gene therapy injection halts spinal muscular atrophy

BBC - 08-Mar-2021

Becomes most expensive drug ever approved for the NHS - but no lifetime costs

Stay young making new blood even at an older age

University of Colorado Anschutz Medical Campus - 08-Mar-2021

Instead of young blood transfusions, why not make your own blood more youthful?

Whales revealed clues in fight against ageing and cancer

CNN - 07-Mar-2021

Positive evolution, gene duplications are linked to longevity and anti-cancer traits of cetaceans

Elastrin's novel therapies to reverse age-related vascular damage

Longevity Technology - 04-Mar-2021

Advancing technologies for tissue and organ rejuvenation with seed funding from Kizoo

Flagellin vaccine can help reduce harmful gut bacteria

Fight Aging! - 03-Mar-2021

Favorable results in single person experiment calls for a larger and formal research

Rejuvenate Biomed raises 3.2 million euros for anti-ageing drugs

PharmiWeb.com - 02-Mar-2021

Accelerates clinical trial plans for its lead candidate Rlx-01 targeting age-related muscle failure

Small mobile stem cells finds use in cell therapy for lung conditions

CISION PR Newswire - 02-Mar-2021

SMS cells play a significant role in lung repair and regeneration, and other inflammatory diseases

CRISPR cuts cholesterol by 57% with just one shot

Phys.org - 01-Mar-2021

Tiny lipid particles with gene editing machinery selectively targets liver and reduces cholesterol in mice

Autologous stem cell grafts treated Parkinson’s disease in monkeys

University of Wisconsin-Madison - 01-Mar-2021

A potential application in humans for Parkinson's with nerve grafts made from own stem cells

3D printed biomaterials can help treat neurodegenerative diseases

Health Europa - 26-Feb-2021

Biomaterials can form superstructures to help regenerate patient derived neuronal cells

A neural protein in blood can predict your lifespan

Lifespan.io (LEAF) - 25-Feb-2021

NFL protein increases with neurological diseases: a potential biomarker for ageing and longevity

Longevity pharmacology promises to revolutionize healthcare industry

Lifespan.io (LEAF) - 24-Feb-2021

Despite challenges, many companies and clinical trials in longevity field are constantly evolving

Goya et al review progress in cell reprogramming

Live Forever Club - 24-Feb-2021

Considers whether, and impact if, epigenetic clock is one component of a modular ageing mechanism

Genetically engineered cartilage combats inflammatory arthritis

National Institute on Aging (NIA) - 24-Feb-2021

Engineered cells produce anti-inflammatory drug that helps reduce stress-related cartilage damage

Body's own drug, spermidine prevents age-related pathologies

Innovation Origins - 23-Feb-2021

Spermidine supplemented mice showed anti-ageing effects by preserving telomere length

Artificial muscles in regeneration of damaged skeletal muscle

Science Daily - 21-Feb-2021

Hybrid constructs help regrow muscle tissue forming new blood vessels in mice

Gut microbiome impacts healthy ageing and survival in humans

Medical Xpress - 18-Feb-2021

Microbiome becomes unique starting in the mid-life, correlates with blood metabolites

Lab grown bile duct organoids could restore liver health in humans

Medical Xpress - 18-Feb-2021

Cholangiocyte-based therapy repairs bile ducts, offers hope to repair damaged donor livers

Immune system links personality traits to lifespan

Irish Times - 17-Feb-2021

Insights on this missing link may offer new interventions for health and longevity in the future

Investment venture launches $10M for Scottish life sciences firms

BBC - 16-Feb-2021

Eos Advisory and Kineticos collab will help find treatment for incurable cancers

Bionic eye implant will restore vision to the blind

CISION PR Newswire - 16-Feb-2021

Medical Research Future Fund Grants AU $1M to progress vision processing software

Super summary of 3rd Annual Longevity Therapeutics Summit

Lifespan.io (LEAF) - 16-Feb-2021

More and more companies making greater and greater progress - 2021 could be an exciting year

Tackling multiple dysfunctions together can stop ageing signs

Lifespan.io (LEAF) - 12-Feb-2021

NAD+ levels, senescence and chronic inflammation collectively influence ageing

Macrophages trigger stem cells for wound repair and regeneration

Sydney Morning Herald - 11-Feb-2021

Macrophages and stem cell interaction promotes muscle repair in zebrafish and mice models

Can short-term immune memory impact longevity?

Medical Xpress - 11-Feb-2021

Less inflammation due to shorter immune memory prolonged life of blind mole rats

Stroke rates declined in older adults of Denmark

American Academy of Neurology (AAN) - 10-Feb-2021

With the improvements in awareness and better patient care, death rates and incidence of stroke decreased

Cambrian Biopharma raised $60 million in stealth mode

Longevity Technology - 09-Feb-2021

New York-based biotech company with unique approaches to treat age-related diseases

What was the International Longevity Alliance up to in 2020?

International Longevity Alliance - 08-Feb-2021

Yearly report of their activities including policy papers, senolytic research and an activism prize

NAD+ reduces age-related amyloidosis and mitochondrial dysfunction

Lifespan.io (LEAF) - 05-Feb-2021

Boosting NAD+ levels improves health span and can treat age-related diseases

A look at the government consultation on genetic technologies in agriculture

Nuffield Council on Bioethics - 04-Feb-2021

Two kinds of question that people ask about developments in life sciences and biotechnology:

Stool transplants help skin cancer patients respond to immunotherapy

Guardian - 04-Feb-2021

Poop to pill: fecal transplants restore healthy gut microbes boosting immunity to fight cancer

Gradual weight gain can help you live longer

Yahoo! Style - 03-Feb-2021

Life-course BMI analysis revealed association between weight gain and mortality

Cellino raises $16M scaling up personalized regenerative medicine

Longevity Technology - 02-Feb-2021

Biotech startup to make stem-cell based therapies to extend and save lives

Human stem cells reduced Parkinson's symptoms in rats

Lifespan.io (LEAF) - 02-Feb-2021

Reprogrammed stem cells treated Parkinson's in rats; initiating clinical trials soon

Centenarians report exceptional cognitive performance

Alzforum - 02-Feb-2021

Despite age-related risk factors, super-agers had only a slight decrease in memory

Proteins from parasitic worms could be the next anti-ageing therapy

Science Daily - 02-Feb-2021

Helminth parasites may provide protection against inflammation disorders

Emil Kendziorra explains how Tomorrow Biostasis will cryopreserve your body

Sifted - 02-Feb-2021

Good to have another cyronics provider in Europe

Bioprinting offer cutting edge tech advancements in healthcare

Asia Times - 29-Jan-2021

Korean startup on regenerative therapy creates living tissues, potential of replacing organs too

Lab-grown human muscle showed benefits of exercise

INVERSE - 29-Jan-2021

Tissue engineered muscle under simulated exercise prevented chronic inflammation

Mitrix gains funding to transfuse young mitochondria

Longevity Technology - 28-Jan-2021

Trials on mitochondrial transfusion might help tackle many ageing diseases

Automating healthy lifespan studies using nematodes

Kumamoto University - 28-Jan-2021

New automated system with AI searches genes, drugs to extend human healthy lifespan

Irina Conboy explains latest blood plasma dilution results to lifespan.io Journal Club

Live Forever Club - 27-Jan-2021

Conboys are planning a modified lifespan study - looking for funding

Rapamycin might not be an alternative for calorie restriction

Lifespan.io (LEAF) - 27-Jan-2021

Failed to mimic dietary restriction pathways on extending lifespan in progeroid mice

Life expectancy in UK women declined by 5 months during 2014-19

Daily Mail - 25-Jan-2021

Reported major drop in women than men; Post-pandemic data could be the worst

Wireless brain communication could soon be a reality

EurekAlert! - 25-Jan-2021

Post-demo on rodents, researchers to begin brain-brain communication in humans

Oisín Biotechnologies' gene therapy may be available in the next 5 years

Longevity Technology - 22-Jan-2021

Results in mice suggest that it can increase median lifespan in humans by 15 years

Whole-body senescent cell removal improved brain health in mice

Lifespan.io (LEAF) - 22-Jan-2021

Senolytic drug and cancer drug with quercetin improved age-related cognition

Rubedo to first work on lung diseases

Longevity Technology - 20-Jan-2021

Their work will be critical amidst the COVID-19 pandemic - to move into clinical trials soon

Gerostate Alpha looks at ageing in an unbiased way

Longevity Technology - 20-Jan-2021

Instead of targeting specific hallmarks/pillars - they want to target ageing as a whole

New evidence on reversing cognitive ageing in aged mice

The Scientist - 20-Jan-2021

EP2 receptor which causes inflammation & ageing was knocked down in a disease model

Deactivating ageing gene KAT7 to slow down ageing

Reuters - 20-Jan-2021

A potential therapeutic target for ageing, but still a long way to human trials

After covid vaccine, Oxford to tackle antibiotic resistance

BBC - 19-Jan-2021

Expert researchers to address antibiotic resistance with the £100m fund by Ineos

Genes may partly influence your eating habits, study finds

Science Daily - 19-Jan-2021

Dietary indices found heritable food and nutrient patterns among female twins

New approach to bring 3D functional organs to reality

University of Washington - 18-Jan-2021

Hydrogels in tissue engineering with cell signaling protein combinations

Medical agent removes senescent cells to fix aging-related diseases

Japan Times - 16-Jan-2021

With positive results in mice, scientists expect to slow down ageing in humans

SRF's End Of Year Campaign receives $1M from Antonov Foundation

SENS Research Foundation - 16-Jan-2021

Raises a total of $2M dollars this year amidst the pandemic

Better policies are needed for healthy ageing

PoliticsHome - 15-Jan-2021

Govt unlikely to achieve its target of adding 5 healthy years by 2035 based on current trends

Has Metformin received too much of an attention as an anti ageing drug?

Fight Aging! - 14-Jan-2021

Studies show promise with metformin - tiny positive outcomes with side effects

Scientists reprogram fat cells to stem cells

Phys.org - 14-Jan-2021

Let's hope other stem cell treatments are closer than 15 years away

Interview with National Institute on Aging Scientific Director

Nature Aging - 14-Jan-2021

Most hallmarks of aging only described in mice, so far, but Luigi Ferrucci is still optimistic

A force of tissue stiffness could bring new changes to immune drugs

Buck Institute - 12-Jan-2021

Tissue stiffness alter immune system response to chronic diseases and ageing

Turn Bio licenses mRNA technology to undo ageing effects

Longevity Technology - 12-Jan-2021

A revolutionary technology research to provide the cure for age-related diseases

SENS summarises young blood experiments including recent human plasma exchange

SENS Research Foundation - 11-Jan-2021

Dilution Solution hypothesis better explains the effects of parabiotic experiment & TPE

Fraility maybe a better marker for ageing than telomere length

Longevity Technology - 07-Jan-2021

Telomere length may not be an accurate indicator of lifespan & health in the elderly

Biodegradable heart valves and vessels tested in pre-clinical trials

Eindhoven University of Technology (TU/e) - 07-Jan-2021

Could eliminate the risks of traditional non-degradable permanent prostheses

Scientists find the reason for impaired DNA repair in aged cells

Lifespan.io (LEAF) - 06-Jan-2021

Unveiled the mechanisms for DNA impairment; laid foundation for future research

A gene editing tool used to treat progeria in mice

Science Magazine - 06-Jan-2021

Hope to launch a clinical trial in kids soon using this approach

Progress on human ageing studies with Dunkin Hartley guinea pig

Colorado State University - 06-Jan-2021

Animal model studies that help in better understanding musculoskeletal ageing

R42 group launched $14 million funds aiming to extend longevity

Longevity Technology - 06-Jan-2021

Funding targets early-stage companies and postdoc researchers with unique ideas

Gene therapy prevented deafness in mice with genetic defects

ISRAEL21c - 04-Jan-2021

Scientists to use this approach & treat deafness due to other mutations also

Inhibition of mitochondrial DNA might suppress tumour growth

Nature - 04-Jan-2021

IMTs degraded 1 in 3 cancer cell lines in vitro, and early promise in mice

Andrew Steele shares his thoughts on ageing

Guardian - 03-Jan-2021

Echoes some thoughts from his book "Ageless: The New Science of Getting Older Without Getting Old"

118 year old World's Oldest Person aims to live till 120

Japan Times - 02-Jan-2021

I wouldn’t suggest drinking Coke as part of your longevity diet!

FDA approved LyGenesis' phase 2a trials on liver failure patients

Longevity Technology - 30-Dec-2020

Raised $11M funding which goes into trials and developing functional organs

Stem cells protect chromosomal ends differently than normal cells

The University of Sydney - 26-Dec-2020

Insights on this unique strategy could have breakthrough treatments for ageing and many diseases

Telomere shortening - a new milestone in cancer therapy

Medical News Today - 25-Dec-2020

Shortening telomere length in cancerous cells will prevent them from dividing

Activewear brand Lorna Jane makes 'anti-virus' claims: taken to court

BBC - 23-Dec-2020

Such claims made by trusted companies without a scientific basis mislead the public

Engineered genes in gut bacteria might help you live longer

Forbes - 23-Dec-2020

Green light activated E.coli genes, extending life in Caenorhabditis elegans

Group of Russian biohackers perform the first human plasma dilution

Lifespan.io (LEAF) - 22-Dec-2020

Results aren't published in any journal but might be the first step towards more human studies

2020 might be the deadliest year for America

Guardian - 22-Dec-2020

Life expectancy to drop by 3 years - greatest cut off since World War II

Heales funds young plasma longevity studies

Heales - 22-Dec-2020

Many people were disappointed that Katcher didn't report lifespan impact - this is about to change

Points to consider in a biological clock

Aging Matters - 21-Dec-2020

Biological clocks should make sure they're using 'causes' and not 'effects' of ageing

A gene mutation that protects and improves brain function

Medical Xpress - 21-Dec-2020

Super agers with a rare gene mutation counteracts accumulation of aging proteins

Studies on melanocyte stem cells to prevent or reverse gray hair

Washington Post - 19-Dec-2020

Greying of hair is irrespective of age and gender; Scientists work on stem cells

Antihypertesive drug found a new purpose in ageing

EurekAlert! - 18-Dec-2020

Big gains in c. elegans life expectancy rarely translates to humans, but another avenue to research

Data from individual cells holds the key to a longer & healthier life

Science Business - 17-Dec-2020

Aim to intervene in ageing-related diseases before they cause harm. Sounds like curing ageing!

Highlights from eLife's Aging, Geroscience and Longevity Symposium

eLife Sciences - 17-Dec-2020

Authors covered biological age clocks, senescent cells, longevity genes, and more

AI based aging clock predicts psychological age

Longevity Technology - 16-Dec-2020

Deep longevity's psychological clock might help you feel younger and live longer

It's high time for people in UK to consider vitamin D supplements

Independent - 16-Dec-2020

A study in UK records shocking levels of vitamin D deficiency in certain groups

LMC provides background and success outlook on 14 leading senolytic companies

Longevity Marketcap - 15-Dec-2020

Comprehensive review of companies' clinical and financial state of play

Levels' CGM technology to help augment metabolic health

Longevity Technology - 14-Dec-2020

Tracks your blood glucose in real time - helps optimise diet and exercise

A mushroom compound that could prevent telomere shortening

NutraIngredients-USA - 14-Dec-2020

Antioxidant ergothioneine alleviates harmful effects of oxidative stress on telomere length

Reversing heart damage with zombie cell-killing drug

British Heart Foundation (BHF) - 14-Dec-2020

Senescence killing drug in mice might unveil new heart attack treatments

Cray X exoskeleton built to develop health & work productivity

TechCrunch - 14-Dec-2020

German Bionic raises $20M fund in Series A to develop its exoskeleton technology

Red light therapy could be the clue to restore your eyesight

China Global Television Network (CGTN) - 13-Dec-2020

Red light improved health and lifespan of fruit flies; might work on humans too

Thymus regenerated from human cells in mice

Medical Xpress - 11-Dec-2020

Will help treat diseases due to immunodeficiency or autoimmunity

Protein that regulates muscle function in ageing discovered

Stanford School of Medicine - 10-Dec-2020

Blocking it improved muscle strength & function while endurance was also boosted in mice

Covid-19 has reverted life expectancy levels back to 2010

Guardian - 10-Dec-2020

Coronavirus slashed the upward trend of life expectancy in England and Wales

Working group appointed for in-depth inquiry into the future of ageing

Nuffield Council on Bioethics - 10-Dec-2020

High-calibre individuals with expertise in biology, public health, technology, and philosophy

A new ageing clock that reveals your biological age

Longevity Technology - 09-Dec-2020

DeepMAge is an accurate ageing clock so far and could be a key in medicine

Kidney Stem cells found in Urine

Lifespan.io (LEAF) - 09-Dec-2020

Will help in kidney tissue engineering and regenerative medicine

Early intervention before disease progression using glyhealth

Longevity Technology - 08-Dec-2020

Avenna's glyhealth alerts practitioners about subclinical chronic inflammation

CRISPR's gene editing therapy finds cure for blood cancer

STAT - 05-Dec-2020

Early data from Vertex & CRISPR showed promising results to cure blood disorders

Free radicals might actually be good for your brain

EurekAlert! - 04-Dec-2020

Control neurogenesis by causing nerve stem cells to divide & thus help brain adapt in mice

Nurse turned healer made false claims to cure the incurable

Metro - 04-Dec-2020

Not only is there no cure for AD, worse, there could be harmful ingredients in miracle tonics

Bioage's lead therapies moved closer to the clinic

Longevity Technology - 03-Dec-2020

Lead therapies of BioAge to treat age related diseases enter phase 2 trials

Genetically engineered T cells destroy pathogenic T cells in mice

Medical Xpress - 03-Dec-2020

Directing T cells to attack other T cells - a new treatment for autoimmune diseases?

Vision loss due to age & glaucoma reversed in mice

Medical Xpress - 02-Dec-2020

David Sinclair says findings are 'transformative for the care of age-related vision diseases'

Study supports link between ageing, telomere length & cancer

New Atlas - 02-Dec-2020

Telomere shortening might be a protective measure to ward off cancers as we age

Memory retrieval made possible with a resetting drug

Medical Xpress - 01-Dec-2020

An experimental drug restores age related memory loss and brain function in mice

Technology Networks interviews Prof Overall about the Human Proteome Project

Technology Networks - 01-Dec-2020

Proteomics is integral to accurate diagnosis and treatment for personalised medicine

MIT professor Richard Young explains how Omega regulates gene expression

Cell and gene - 01-Dec-2020

Using Epigenomic Controllers to alter DNA transcription rather than the genes themselves

Donations being triple matched for SENS end-of-year fundraiser

SENS Research Foundation - 01-Dec-2020

I've just donated to help #UnlockLongevity - these are the experts and they need funding!

Deepmind's AI program has decoded a protein mystery

Guardian - 30-Nov-2020

Will help in developing designer meds, better crops & 'green enzymes' to counter pollution

A new enzyme discovered to reverse cellular ageing

Phys.org - 30-Nov-2020

Molecular simulations have discovered an enzyme with anti ageing and anti tumour effects

Number of births may decide how fast you age

Science Daily - 30-Nov-2020

Less than 3, or more than 4, results in accelerated ageing after menopause

A new epigenetic clock that can predict your mortality risk

Lifespan.io (LEAF) - 26-Nov-2020

GrimAge can accurately predict all cause-mortality than any other clock

Relive post-death: A pensioner signed to deepfreeze

Metro - 26-Nov-2020

A 73yr old believes in future technology and signed up for cryopreservation

Hidden inflammapath in your mouth invites deadly diseases

Longevity Technology - 25-Nov-2020

Keystone Bio's first ever biologic on the planet to eliminate oral pathogen

Eye-opening facts about human skin ageing

Chinese Academy of Sciences (CAS) - 25-Nov-2020

Therapeutic strategies to combat human skin diseases at single-cell level

A new FDA approved drug offers hope to children with progeria

Science News - 25-Nov-2020

Zokinvy blocks production of a defective protein to lengthen the shortened life span

Decoded - why travelling through space can make you older

iNews - 25-Nov-2020

Mitochondrial damage accelerates ageing on exposure to space radiation and microgravity

Targeting senescence might help fight cancers

Longevity Technology - 24-Nov-2020

Senolytics to treat cancers - study finds correlation between senescence & survival

Drug guided stem cell migration improves healing in mice

Science Daily - 24-Nov-2020

First ever drug guided stem cell therapy in the field of regenerative medicine

Elevian raises $15M in preclinical work towards clinical antiaging

FierceBiotech - 24-Nov-2020

rGDF11 in clinic targets multiple age related disease therapies

Transgenic obese mice that do not suffer from being fat

Lifespan.io (LEAF) - 24-Nov-2020

Scientists discover a pathway to attenuate the deleterious effects of obesity

A fibrin based hydrogel for liver regeneration

Lifespan.io (LEAF) - 20-Nov-2020

Could be used to develop livers for transplantation and organ on chip testing

A rare gene mutant variant found to protect liver by chance

EurekAlert! - 19-Nov-2020

Scientists found exciting benefits by inducing a gene mutation in mice

Johnson & Johnson unveil a new robotic platform 'Ottava'

MassDevice - 19-Nov-2020

Plan to integrate it with their FDA approved Monarch robotic surgical system

Regenerating heart vessels to replace traditional surgeries

University of Helsinki - 19-Nov-2020

Stimulating growth factor to grow new blood vessels in the heart of mice

Oxygen therapy reversed the human age biologically

YAHOO! - 18-Nov-2020

Not as easy as taking a pill, but a stunning result on both telomeres and senescent cells

A novel gene editing tool to fight aggressive cancers

Medical Xpress - 18-Nov-2020

Uses CRISPR technology to target and destroy cancer cells

Dilution of old blood restores healthy brain function

Lifespan.io (LEAF) - 17-Nov-2020

Reduces neuroinflammation & promotes neurogenesis in aged brains of mice

A drug that reverses ageing to help fight COVID

Connecticut Post - 17-Nov-2020

Elderly have a higher mortality risk with COVID - reversing ageing could reduce it

Chronic inflammation promotes NAD+ decline during aging

Buck Institute - 16-Nov-2020

Senescent cells induce NAD+ decline via activation of CD8 macrophages

A new study links Alzheimer's to gut flora

New Atlas - 15-Nov-2020

Altering gut microbiome might be helpful in preventing or delaying Alzheimer's

Age limits health span benefits of metformin in worms

Medical Xpress - 12-Nov-2020

Scientists link metformin toxicity with age in young,old non diabetic organisms

Exposure to old cells can make young cells old

Lifespan.io (LEAF) - 12-Nov-2020

Path to a new therapy- replacing blood with youthful factors might reverse ageing

Nature Biotechnology reviews the state of play of senolytics

Nature Biotechnology - 12-Nov-2020

In August, Unity announced that its lead drug candidate had failed to beat a placebo in reducing joint pain and stiffness.

Scientists manufactures artificial organoids using automation

Lab Manager - 11-Nov-2020

Semi-automating tissue differentiation makes artificial tissues at a faster rate

Walnut - a super nut for a healthy heart

Genetic Engineering & Biotechnology News (GEN) - 10-Nov-2020

Decreases chronic inflammation and the risk of cardiovascular disease

Study links gut flora with Parkinson's and Alzheimer's

The Conversation (UK) - 10-Nov-2020

Microbiome altering might help in preventing or delaying Parkinson's and Alzheimer's

A research collab to explore new approaches for skin restoration

Avita Medical - 09-Nov-2020

AVITA Therapeutics and the Houston Methodist Research Institute enter research collaboration

A novel approach unlocked a gene's purpose on immune system

Medical Xpress - 09-Nov-2020

Study in mice and humans found CRELD1 gene's role in immune cell aging

Reason reviews the research behind One Skin's senotherapeutic skin-care spray

Fight Aging! - 06-Nov-2020

The anti-ageing peptide promotes skin health and reduces senescent cell markers

OTC drug Ibuprofen could reverse age associated inflammation

Longevity Technology - 06-Nov-2020

A study on mice supported ibuprofen for use in neurodegenerative diseases

NAD precursor could prevent telomere loss

Longevity Technology - 04-Nov-2020

Restoring NAD homeostasis could help in ageing diseases with telomere dysfunction

A potential therapy for blinding retinal diseases

National Institutes of Health (NIH) - 03-Nov-2020

Researchers engineer novel protein that restores vision in blind mice via gene therapy

Lack of gene coordination during aging calls for newer treatments

Bar Ilan University - 03-Nov-2020

Researchers found a new link in aging from a 15yr old approach

Advances in stem cell cures by new biotech startups

GEN News - 03-Nov-2020

New generation companies develop novel cell therapies using stem cells

A clock that tells how ageing brain could be linked to dementia

Science Focus - 29-Oct-2020

Will explain why some brains age faster and make people susceptible to certain diseases

Metformin with Resistance Training- To do or not to do?

Lifespan.io (LEAF) - 29-Oct-2020

Metformin might inhibit muscle building but makes gene expression more youthful

Scientists discover a life threatening inflammatory disease

WorldHealth.Net - 27-Oct-2020

Called VEXAS- discovered using a novel genome first strategy

Longenesis enables Deep Longevity to develop more ageing clocks with access to more data

Longevity Technology - 23-Oct-2020

Interoperability has always been problematic in healthcare - we really need to crack it for ageing research

A step towards understanding the molecular mechanism of ageing

Lifespan.io (LEAF) - 22-Oct-2020

A core set of genetic regulators involved in ageing have been found

Say goodbye to fine lines and wrinkles with OneSkin

Longevity Technology - 21-Oct-2020

Topical supplement which extends skin span-the period of time your skin is healthy and youthful

Mechanism underlying telomere restoration in T cells discovered

Lifespan.io (LEAF) - 20-Oct-2020

Telomere transfer from APCs boosts T cells lifespan-helpful in immunosenescence

Genes of some species might hold the key to human longevity

The National Academies of Sciences, Engineering, and Medicine (NASEM) - 19-Oct-2020

Studying organisms that live long will help identify crucial genes associated with ageing

Big investors join First Longevity funding round

Longevity Technology - 16-Oct-2020

Key investors raise funding to support longevity sector

Pharma company teams with AI to develop anti aging solutions

Longevity Technology - 15-Oct-2020

Taisho and Insilico collabs to identify novel targets for senolytic drugs

Unity Biotechnology launches clinical trial of a new senolytic

Lifespan.io (LEAF) - 13-Oct-2020

A new approach to treat diabetic macular oedema

New discovery explains mechanism regulating telomere length and function

Phys.org - 13-Oct-2020

Now we can better understand processes that regulate cell survival in ageing

Improving immune system in the elderly with the existing medicines

The Conversation (UK) - 13-Oct-2020

Repurposing the potential existing drugs might eliminate the risk of developing infections

Tiny lipid bubbles could deliver gene editing kit to your tissues

Phys.org - 08-Oct-2020

Will make it easier to target treatment to specific locations in the body

Regenerating eyes could be a reality

ScienceAlert - 08-Oct-2020

Temporarily reactivating dormant genes could allow body to repair and regrow retinal cells

Meet Kris Gethin - a Welsh biohacker

WalesOnline - 04-Oct-2020

From coffee enemas to pants blocking EMF radiation - his routine is straight out of a sci fi movie

Skin regeneration reactivated in adult mice

Medical Xpress - 29-Sep-2020

New skin was able to produce fur - might eventually become a treatment for baldness, who knows

Tumor regression achieved with single 3-pronged immunotherapy injection

Lifespan.io (LEAF) - 29-Sep-2020

IL-12 self-replicating RNA delivered in lipid nanoparticles (LNPs) shows good results in mice

Jim Mellon plans to take his longevity company Juvenescence public

CNBC - 29-Sep-2020

The company with $170 million private funding has invested in various life extension therapies

Flavonoid found in redcurrants reduces senescence in brain cells

Lifespan.io (LEAF) - 28-Sep-2020

Mice study also saw improved cognitive abilities

Another milestone towards regenerative medicine

University of Calgary - 28-Sep-2020

Now we can produce large quantities of human pluripotent stem cells

Mechanism to prevent hair loss discovered in mice

ScienceDaily - 28-Sep-2020

Lifespan of hair follicle stem cells can be prolonged by changing their metabolic state

Ethical challenges for human augmentation technology

IT PRO - 26-Sep-2020

Advancement in human augmentation doubts human safety and equality

New technique to measure individual telomere lengths in 3 hours

Phys.org - 25-Sep-2020

Not just average length that is important, so full profile provides more clinical uses

Microrobots might treat nerve injuries in the near future

Science News - 25-Sep-2020

A magnetically controlled microrobot connects clusters of nerve cells

Increase in life expectancy is not just due to fall in child mortality

Our World in Data - 23-Sep-2020

Life expectancy at birth has doubled since the mid 19th century

Elderly nowadays have an improved physical & cognitive performance

Science Daily - 21-Sep-2020

Study compared functional ability between cohorts of same age but 30 years apart

Illumina reunites with cancer testing firm Grail, worth $8 billion deal

FierceBiotech - 21-Sep-2020

Marks new era in advancing screening and early diagnosis of cancer technology

One in every 1500 people is a centenarian in Japan

CNN - 18-Sep-2020

Japan has the highest life expectancy in the world and homes the oldest person alive

Measuring frailty with blood biomarkers could lead to early detection

Longevity Technology - 14-Sep-2020

Circulating CRP and albumin (among other molecules) found to be related to frailty

Extending the healthspan without restricting calorie intake

Medical News Today - 13-Sep-2020

Metabolites vital for pro-longevity effect of calorie restriction can help develop drugs

Double-strand break DNA repair improved in calorie restriction mice

Lifespan.io (LEAF) - 10-Sep-2020

Helps us to understand the mechanism behind CR - and that it has an effect within weeks

Everything you ever wanted to know about AKG (but were afraid to ask)

Lifespan.io (LEAF) - 07-Sep-2020

A great summary of the history,biochemistry and life-extending potential of alpha-ketoglutarate

Worse off disproportionally affected by air pollution and poor environment

Guardian - 07-Sep-2020

Improved air quality and access to nature would improve everyone's health

Anti inflammatory peptides discovered in rice using Nuritas' AI program

Longevity Technology - 03-Sep-2020

Peptides reduce inflammaging and improve standardised physical tests

Longevity.Technology interviews Adam Freund - Calico’s Principal Investigator

Longevity Technology - 02-Sep-2020

Will be presenting a viable therapeutic strategy using IGF signaling at ARDD 2020

Body builder supplement AKG extends lifespan and healthspan of mice

Buck Institute - 01-Sep-2020

Blood levels fall with age. NUS planning a clinical trial with middle-aged humans.

Eating junk food could make you age faster

ScienceAlert - 01-Sep-2020

Study finds link between ultra processed food and shorter telomeres

Josh Mitteldorf on monitoring blood glucose while taking metformin and berberine

Aging Matters - 31-Aug-2020

Eating habits and exercise alter blood glucose levels - wearables may help get a rough idea

Labiotech gathers feedback from European biotechs on Unity failure

Labiotech - 28-Aug-2020

General feeling that failures are bound to happen - but that their approaches can succeed

Lygenesis announces four peer reviewed papers on organ regeneration

Longevity Technology - 28-Aug-2020

Takes us a step ahead towards regenerating organs for human diseases

IBM develops an online chemistry lab 'RoboRXN'

MIT Technology Review - 28-Aug-2020

Will lower the cost & speed up the process of developing drugs

Old mice show improved muscle function with gene therapy

Lifespan.io (LEAF) - 27-Aug-2020

A single injection could treat motor diseases of the aged but needs more human studies

Here are some longevity tips from Japan's 105 year old expert

CNBC - 26-Aug-2020

Dr. Hinohara gives life advice on how to live longer, happier and healthier

New research with senolytics shows promising results

Longevity Technology - 25-Aug-2020

Senolytic research is in its nascent stage but no reason why one shouldn't be hopeful

World's oldest man dies aged 116 - RIP Fredie Blom

BBC - 22-Aug-2020

A great example of compressed morbidity - Fredie was still active 2 weeks before his death

Bayshore latest drug maker to recall metformin after carcinogens found

FiercePharma - 21-Aug-2020

A good example of why you have to be careful buying meds - even big pharma has problems.

Humanity health app to track and slow down your ageing process

TechCrunch - 20-Aug-2020

App that monitors both digital and biomedical markers, sets for launch in 2021

90 % of herpes simplex virus 1 eliminated in infected cells

Lifespan.io (LEAF) - 19-Aug-2020

Successful in mice, new approach may ease immune burden of herpes in humans in the future

Telomerase gene therapy prevents age-related lung fibrosis in mice

Pulmonary Fibrosis News - 19-Aug-2020

Could pave way for preventing the disease in humans and improve healthspan

Good physical health could boost ageing mind

Medical Xpress - 19-Aug-2020

Declining muscle strength and ageing cognitive function are linked

Reason examines the failure of Unity Biotechnology's phase 2 senolytics trial

Fight Aging! - 18-Aug-2020

Disappointing first result - but lessons learnt and plenty of other strategies available

Shielded stem cells repair heart attack injuries in rodents

RICE UNIVERSITY - 18-Aug-2020

Bioengineered minimally invasive shielded stem cells reduces heart attack damage

Method to regenerate joint cartilage in adults, discovered

Stanford School of Medicine - 17-Aug-2020

Principle tested and a success in mice and humans, to ease arthritis in the future

A single test that can measure your longevity status

Longevity Technology - 17-Aug-2020

Insights can tell what you should and shouldn't do to improve your longevity status

New app helps identify biological age and methods to slow it down

Fortune - 17-Aug-2020

Apps such as Young. ai will play a key role in helping understand and reversing aging processes

Middle-aged mice live 10% longer with 4 days of CASIN injections

Lifespan.io (LEAF) - 14-Aug-2020

It would be interesting to see how long they lived with regular treatment through old-age

A step closer to reversing pulmonary fibrosis via telomerase gene therapy

Lifespan.io (LEAF) - 12-Aug-2020

Study in mice revealed great progress and potential for curing fibrotic diseases in humans

Gut microbiome of centenarians changes a few months before death

Fight Aging! - 11-Aug-2020

Causation vs correlation to be confirmed - but death affects ALL cells in the body, not just YOUR cells

A protein for regulating circadian cycle also fights cellular senescence

Lifespan.io (LEAF) - 11-Aug-2020

Its upregulation could be a new prospect for anti-ageing interventions

Low stress hormone levels promotes premature ageing

Longevity Technology - 11-Aug-2020

Balance is key to everything especially with human body

AI firm Lapetus uses facial recognition for longevity studies

Longevity Technology - 11-Aug-2020

In 60 seconds, can identify ones rate of ageing, BMI, among others

Genes of the oldest humans alive hold the key to human longevity

Singularity Hub - 10-Aug-2020

This time, focusing on the narrow population, the centenarians, would give us answers

Regulatory role of GDF 15 related to ageing and metabolism in humans and mice

Longevity Technology - 06-Aug-2020

Discovery of this homeostatic function just may be the first step but it looks promising

Copying naked mole-rat living conditions can extend lifespan

Haaretz - 06-Aug-2020

Demonstrated in mice, far from human trials, but a potential longevity intervention

Benefits of caloric restriction in intestinal stem cells

Lifespan.io (LEAF) - 05-Aug-2020

One should still consume adequate nutrition while reducing calorie intake

$95M raised by Taysha for clinical trials of four new gene therapies

FierceBiotech - 05-Aug-2020

Company has gathered support from investors to quickly lead therapies to clinic then market

Bringing regenerative technology to patients

Longevity Technology - 04-Aug-2020

Commercialization of tissue and organ regeneration process for clinical use

Longitudinal DNA methylation is influenced by genetic, environmental factors

Longevity Technology - 03-Aug-2020

Decade-long studies of identical twins were able to reveal connections

What does is mean to 'die of old age'?

Gizmodo - 03-Aug-2020

Experts raise some interesting end-of-life questions - ones which will soon, hopefully, be obsolete

VRK-1/AMPK cellular energy pathway linked to longer lifespan

New Atlas - 02-Aug-2020

Early days, but looking forward to seeing the results (in vivo) in mammals

Exercise reduces inflammation caused by SASP but not the number of senescent cells

Fight Aging! - 31-Jul-2020

Given senolytics are unlikely to ever clear every senescent cell, exercise will still minimise bad effects of those remaining

Omega Therapeutics raises $85m for Epigenomic Controllers

Endpoints News - 29-Jul-2020

New gene expression therapy for various targets, with clinical trial planned for 2021

Taking the new path in the field of senolytics - SENISCA

Longevity Technology - 29-Jul-2020

Old cells will be more young and beautiful

Cohort study: Glucosamine reduces mortality by 15%

Fight Aging! - 28-Jul-2020

Supplementation with this anti-inflammatory drug can give us more benefits than we know

Researchers grow gut organoids to identify protein critical for repair

Lifespan.io (LEAF) - 27-Jul-2020

NRG1 treatment boosted activity of gut stem cells - could help protect gut during chemotherapy

Mindfulness meditation prevents shortening of telomeres

Psych Central - 27-Jul-2020

Only a small study (17 meditators) but interesting nonetheless

AstraZeneca partners up with Daiichi Sankyo for cancer drug

Guardian - 27-Jul-2020

New drug could become the best one to target and treat multiple tumours in the future

Doctors to prescribe cycling to prevent obesity related hospital admissions hitting 1 million

BBC - 26-Jul-2020

It's more effective than any drug so why not prescribe it?

3D-printed Lego-inspired bricks, to heal broken bones

Medical Xpress - 25-Jul-2020

Tested some aspects in rats, could make lab-made organs for human transplant possible

Abortion drug mifepristone may help extend the lifespan

Longevity Technology - 24-Jul-2020

Gains in fruit flies and roundworms give insights to extend human health and lifespan

Engineered Micro-Pancreas (EMP) could rectify diabetes

Guardian - 23-Jul-2020

Betalin's biological scaffold holds beta cells that release insulin instead of having to inject it

LEAF interviews Reason about his views on epigenetic clocks

Lifespan.io (LEAF) - 22-Jul-2020

It does seem way to early to be settling for any single type of clock for rejuvenation research

Novel ageing pathway slows ageing of yeast cells in silico

CNN - 21-Jul-2020

It's a long way to go to having an effect in humans in vivo, but an interesting approach

OneSkin cosmetic cream reduces senescent cells in skin

Longevity Technology - 21-Jul-2020

Profit from OS-1 could fund development of more products and clinical trials

Biological age of heart tissue 10 years younger then white blood cells

Fight Aging! - 20-Jul-2020

We need a single biological age figure as mortality risk applies to the whole body

Obesity problem must be treated just like smoking, experts voice out

Guardian - 19-Jul-2020

This includes regulating 'junk food' marketing and consumption

Survey reveals unsettled views of ageing amongst researchers

Mechanisms of Ageing and Development - 18-Jul-2020

Good news is that almost half the researchers believe age reversal is possible - unimaginable 5 years ago

Texas-based Timeship to be capital of cryonics and life extension

Science Focus - 17-Jul-2020

The site has been selected for long-term survival from natural and human-made disasters

LEAF interviews Stephanie Lederman, Executive Director of AFAR

Lifespan.io (LEAF) - 17-Jul-2020

"I would say that the science is now for this field" - I couldn't agree more

Lowering iron levels might hold the key to longevity

ScienceAlert - 17-Jul-2020

Study finds link between ageing and elevated blood iron levels

Continuous trickle of genomic instability can lead to multiple age-related diseases

Lifespan.io (LEAF) - 16-Jul-2020

Analysing mutations in individual cells will help determine its burden on ageing damage

Balancing blood iron levels is the key to living longer

Phys.org - 16-Jul-2020

Genes linked to iron metabolism were also responsible for age related diseases

Longevity.Technology interviews Prof Faragher about his cellular senescence research

Longevity Technology - 15-Jul-2020

Maybe we need to develop senoplasts like resveratrol as well as senolytics

LEAF interviews Alexander Fedintsev about weak v strong ECM hypothesis

Lifespan.io (LEAF) - 15-Jul-2020

It may be a new hallmark of ageing, but it's been one of SENS' 7 strategies since it started

Deep Longevity investors bet on growing need for aging and longevity biomarkers

FierceBiotech - 15-Jul-2020

Biological clocks are a moving target so they'll need other researchers to corroborate their analysis

OneSkin's MolClock algorithm to calculate skin age available for free use by other researchers

OneSkin Technologies - 15-Jul-2020

It would be great if beauty cream manufactures had to publish objective figures for their products

3D printed heart like organoid can contract spontaneously and synchronously

University of Minnesota - 15-Jul-2020

This organoid with chambers can fit into a mouse's belly

Scientists go where no gene-editing tool has gone before

Lifespan.io (LEAF) - 14-Jul-2020

DddA able to target mitochondrial DNA (mtDNA) by splitting in half and hitching a ride

NHRI develops a therapy to regenerate damaged brain cells

Taipei Times - 14-Jul-2020

Exosomes will help reduce complications of using living stem cells for brain repair

Blood factor created by exercise can be transfused to sedentary mice for same mental benefits

Lifespan.io (LEAF) - 13-Jul-2020

Another point for the "good" factors argument, though removing "bad" factors likely to be important too

The blood-brain barrier selectivity is impaired with age

Lifespan.io (LEAF) - 09-Jul-2020

Experiments in mice confirmed this, unraveling ageing mystery if it translates to humans

A gene editing tool to treat mitochondrial mutations

The Scientist - 09-Jul-2020

Derived from bacterial toxin - can make single base pair changes

Transplanting youthful white blood cells reduces inflammation in mice

Lifespan.io (LEAF) - 08-Jul-2020

Targeting immunosenescence could provide benefits throughout the body

Ageing seems to increase the number of repetitive elements in our DNA

Lifespan.io (LEAF) - 07-Jul-2020

Even if it's an effect (not a cause) then REs could act as another biological clock

Company introduces 'gene writing', to surpass CRISPR's limitations

Wired - 07-Jul-2020

New class of gene editors set to remove hurdles of traditional gene therapy

LEAF interviews Edwina Rogers, CEO of the Global Healthspan Policy Institute

Lifespan.io (LEAF) - 06-Jul-2020

It's a different set of skills required to convince government decision makers to change policies

A novel cell therapy to reverse age related impairments

Science Daily - 06-Jul-2020

Physical fitness and immune health restored in aged mice models

Role of immune cells in reversal of aging process- A study in mice models

University of Bern - 06-Jul-2020

Manipulation of Eosinophils in belly fat to promote healthy aging

Hormone in bone restores memory and ability to exercise in old mice

Guardian - 04-Jul-2020

Exercising regularly increases this hormone and benefits muscle and brain

Naked mole-rat's immune system is resistant to cancer

Independent - 02-Jul-2020

Their extreme biology could be key to preventing cancer in humans

Google acquires the Canadian smart glasses company North

BBC - 01-Jul-2020

Many tech giants are competing to dominate the mass market for smart glasses

Low cortisol levels can trigger 'macrophaging'

Medical Xpress - 01-Jul-2020

Learning this age-induced disruption of macrophage functions powers pharmaceutical research

Trial of Rejuvant supplement claims 8 year age reversal

Lifespan.io (LEAF) - 30-Jun-2020

If randomised clinical trial replicates results then I might add it to my stack

Age-related diseases: Common genetic associations and therapeutic implications

Lifespan.io (LEAF) - 30-Jun-2020

With genomic database and statistical tools, more interventions can be discovered

Looking young means you are probably ageing slower

CR VITALITY - 30-Jun-2020

Good genes combined with healthy lifestyle choices can truly make you look younger

Senescent cell inflammatory signals as a new possible biomarker

Lifespan.io (LEAF) - 29-Jun-2020

It could measure biological age and relative health

Human trial results of blood plasma exchange for Alzheimer's

Aging Matters - 29-Jun-2020

Benefits were seen, but overall results are not impressive

Gene editing lowered blood level cholesterol and triglycerides in monkeys

New York Times - 27-Jun-2020

Could prevent not only the complications but the heart disease per se in the future

Some of our organs can outlive us while others die early

BBC - 26-Jun-2020

Ageing related processes affect different organs at a different pace

What are the odds of living up to 100 years?

Fight Aging! - 25-Jun-2020

Study of environmental factors leading to becoming centenarian opposes previous literature

Humanin is a regulator peptide of healthspan and lifespan

Science Daily - 24-Jun-2020

Longer life results in less offspring - sounds like the ideal compromise to me!

Fewer genetic mutations gets few more years added to your lifespan

New Scientist - 24-Jun-2020

Will it be possible to remove such mutations from reproductive cells?

Scientists found a link to balance immunity and longevity

Max Planck Society - 24-Jun-2020

Gene changes in round worm lead an interesting evidence to longevity

Immunotherapy as new approach to battle senescent cells

Lifespan.io (LEAF) - 23-Jun-2020

Successful in mice, it may help treat many age-related disease in human

Forever Healthy Fellowship Program awarded to Dr. Tesfahun Admasu

Forever Healthy Foundation - 23-Jun-2020

His project researches on secondary senescent cells and SASP

Harmful effects of senolytic drug Navitoclax in aged mice

Fight Aging! - 19-Jun-2020

Short-term treatment of this drug demonstrated cytotoxicity among other risks

Is it possible to predict biological age with gut microbiome?

Lifespan.io (LEAF) - 19-Jun-2020

Models and anti-ageing intervention design enables new ageing clock development

How lamins are linked to senescence and ageing

Lifespan.io (LEAF) - 19-Jun-2020

Connections have been elucidated but more research needed to confirm significant links

Gene mutations in DNA may impact lifespan and fertility

Newsweek - 19-Jun-2020

Study accelerated public awareness on genome sequencing & inspires new treatment approaches

Leading longevity researchers to speak at global investment conference

Longevity Technology - 17-Jun-2020

Most people (including me!) won't have enough money to attend, but it's good to see more interest in longevity investments

Genetically engineered T cells can be used to target and kill senescent cells

Medical Xpress - 17-Jun-2020

Tested successfully in mice with liver fibrosis and lung cancer

LEAF interviews the Conboys about rejuvenating mice by diluting blood plasma

Lifespan.io (LEAF) - 16-Jun-2020

This could be a cheap first generation rejuvenation treatment - but wait for clinical trials

Endless benefits of exercise also seen in gut microbiome

The Conversation - 16-Jun-2020

In both metabolic and physical levels, evidences gear towards positive effects

Peptides that shift gut bacteria can reduce heart attack risk in mice

Scripps Research Institute - 15-Jun-2020

Lowering the number of bad gut bacteria reduced artery plaques by 40% - wow!

Bit Bio secures $41.5 M funding to produce human cells

Biospace - 15-Jun-2020

UK-based startup reprogramming stem cells to generate new cell therapies

SENS OncoSENS project suspended due to lack of funds and progress

Lifespan.io (LEAF) - 14-Jun-2020

It's important to keep funding basic research as no one knows where the answers will lie

CRISPR gene editing to cure beta thalassaemia and sickle cell disease

New Scientist - 12-Jun-2020

Didn't change the inherited faulty gene, but gene to switch on fetal haemoglobin production

Increasing ovarian NAD+ improved mitochondrial function in mice egg cells

Lifespan.io (LEAF) - 11-Jun-2020

Supplementation also shown to reverse ovarian ageing

Juvenescence appoints a new CEO for its Epigenetic Division and Souvien Bio Ltd

Juvenescence - 11-Jun-2020

Goal is to develop drugs that target epigenetic mechanisms associated with neurodegeneration

Antiageing antibiotic targets senescent human fibroblasts

Health Europa - 10-Jun-2020

Could lead to new drug discovery against senescent cells and extend lifespan

Cellular pathway and mechanism leading to osteoporosis

Lifespan.io (LEAF) - 09-Jun-2020

Confirmed in murine and human cell study, findings can aid development of new treatments

Microneedle- delivered stem cells to boost wound healing

New Atlas - 09-Jun-2020

Findings open up new possibilities for personalized regenerative medicine

Drug that can safely reverse obesity and insulin resistance developed

Medical Xpress - 08-Jun-2020

Proven in mice study to be non-toxic, nor affects brain hunger cues

Diluting blood rejuvenates old tissues in mice

Aging Matters - 08-Jun-2020

There are things in blood that drives our ageing

Robotic injections for safer, pain-free aesthetic procedures

Medical Expo - 08-Jun-2020

The future new norm to revolutionize how patients get botox and soft tissue fillers

Eating less to live longer? Study in fruit fly finds no benefit

Science Daily - 04-Jun-2020

Life extending benefit of dietary restriction might depend upon genetic makeup

Experts devise newest epigenetic clock for anti-ageing drugs discovery

Lifespan.io (LEAF) - 03-Jun-2020

Showed impressive results based on experiments in vitro and in vivo, but more work to be done

Human stem cells successfully produced hair in mice

Nature - 03-Jun-2020

Major step towards treating baldness, skin diseases, also wounds and scarring

Phase 1 clinical trial for type 1 diabetes cell therapy comes closer

Medical Xpress - 03-Jun-2020

A world-first novel technology to treat the disease is now within reach

Could sea urchins hold the secrets of senescence and longevity?

Fight Aging! - 02-Jun-2020

Possible as these highly regenerative echinoids show extremes of biological ageing

Device by Alkahest to treat dialysis-associated dementia

Longevity Technology - 02-Jun-2020

With phase 2 study announced, hopes are up for end-stage renal disease sufferers

Mini livers out of human skin cells functioned normally in rats

INVERSE - 02-Jun-2020

In the future, tech might stop organ shortage, speed up transplant process, and lower cost

Stress causes hair to become grey but it's a reversible process

Medical Xpress - 02-Jun-2020

If the stress is removed soon after greying has started, reversal is still possible

Scientists develop a new epigenetic clock

Lifespan.io (LEAF) - 02-Jun-2020

The clock accurately predicts biological age & can help develop anti ageing drugs

Are Longeveron's Mesenchymal Stem Cells effective against frailty in ageing?

CISION PR Newswire - 01-Jun-2020

Japan's Pharmaceutical and Medical Devices Agency gives the green light for human trials

BSRA sponsors funding to repair bone fractures in the aged

British Society for Research on Ageing (BSRA) - 01-Jun-2020

Chernajovsky Foundation with BSRA funds for PEPITEM molecule to treat fractures

Could a vaccine be an alternative to senolytic drugs?

Lifespan.io (LEAF) - 29-May-2020

New study in mice demonstrates an intriguing possibility with senescent cells research

ThirdLaw may have designed a way to break crosslinks to reverse tissue ageing

Longevity Technology - 29-May-2020

Whoever controls the shape of a molecule controls what it can do

Forever Healthy Foundation structured review of published senolytics research

Forever Healthy Foundation - 28-May-2020

Little evidence of actual beneficial effects (rather than just biomarkers) so not recommended yet

Experts develop new novel detection method for mitophagy

Lifespan.io (LEAF) - 28-May-2020

A discovery proven to be of help in therapeutic studies of neurodegeneration

World's oldest man passes on his crown

BBC - 28-May-2020

Bob Weighton exhibited many life extending qualities such as keeping interested, socialising and laughing

Fat-derived stem cells repair sun-damaged human skin

EurekAlert! - 28-May-2020

Its anti-ageing action through skin deep regeneration succesfully achieved

Calorie restriction rejuvenates 'brain immune cells' in mice

Fight Aging! - 27-May-2020

Still one of the most reliable interventions when improving long-term health

Crowdsourced samples of metformin from USA contain unacceptable levels of NDMA

New York Times - 27-May-2020

Found only in extended-release versions of metformin, immediate-release versions are okay

Longevity InTime plans to track 400 biomarkers and environmental factors

Longevity Technology - 26-May-2020

Using AI to automatically read data from research paper databases and assess users for 20 diseases

Mice blood proteome analysis reveals new therapeutic target for osteoporosis

Lifespan.io (LEAF) - 26-May-2020

A different perspective for preventing age-related bone loss that affects many

Evidence based on male-centric models of medical research to treat women?

Guardian - 24-May-2020

When treating a female patient consider how significant sex differences can be

A new novel senolytic agent, R406, discovered

Lifespan.io (LEAF) - 22-May-2020

Intriguingly destroys senescent cells without inducing cell destruction

Epigenetic clock of asthma patients reveals valuable information

HCP Live - 22-May-2020

There are lot more to discover and learn about asthma

Is it really possible to train for that 100-year milestone?

BBC - 22-May-2020

New concept of 'Centenarian Olympics' allows humans to die young at an old age

Emil Kendziorra explains why he set up the European Biostasis Foundation

Medium - 21-May-2020

I'm not sure survivable cryonics is an easier problem than ageing, but good to have a plan B

Age-related changes in gut microbiota cause cognitive decline in aged rats

Lifespan.io (LEAF) - 20-May-2020

Restoring microbiome could be one strategy to support healthy longevity

Human gut microbiome is altered by shifting to a ketogenic diet

EurekAlert! - 20-May-2020

Potential research area to find treatment options for autoimmune diseases of the gut

Automated manufacturing of custom-engineered cell lines

News Medical - 20-May-2020

This technology is very promising and has an enormous potential

Bill Maris brings new people for his new venture-section 32

CNBC - 20-May-2020

Calico creator is now investing on frontier technology, healthcare & lifescience

An anti ageing protein found in yeast cells

The Conversation (UK) - 20-May-2020

Works by inhibiting protein metabolism

Fountain secured $6 million Series A-1 financing from Khosla Ventures

GlobeNewswire - 19-May-2020

With a total of $11 million, more in vivo preclinical drug testing to be expected

Cell therapy could be the solution for multiple sclerosis and Huntington's

FierceBiotech - 19-May-2020

Transplanting glial cells in worked in mouse models affected with MS

Orion College ageing research receives 1 million UK pounds from Jim Mellon

Lifespan.io (LEAF) - 18-May-2020

He believes in the importance of boosting immunoresilience among elderly

This enzyme helps reverse age-related neurodegeneration in mice

EurekAlert! - 18-May-2020

Sheds light to potential treatments for age-related cognitive decline, Alzheimer's

Alternative therapeutic strategy for hair regrowth using stem cells

EurekAlert! - 18-May-2020

Clinical trial in androgenetic alopecia patients show an increase in hair density, thickness

Follistatin gene therapy to combat osteoarthritis and obesity

Next Big Future - 16-May-2020

This new approach doubled muscle mass in mice, reduced its fat

Millions of mature human cells can be produced in a mouse embryo

University at Buffalo - 15-May-2020

These mouse models can be used to study about diseases such as malaria and COVID-19

Metformin alleviates inflammaging by promoting autophagy

Lifespan.io (LEAF) - 14-May-2020

With the positive results, drug holds great promise for promoting healthy ageing

Vitamin B3 is a good option to correct the NAD+ deficit in humans

Phys.org - 14-May-2020

NAD+ deficiency is for real and it happens in humans too

The effect of gut microbiota on cognitive decline in aged rats

Fight Aging! - 14-May-2020

First study investigating its effects in the normal ageing process

Immunai, to map immune system for better diagnosis, disease treatment

Healthcare IT News - 14-May-2020

This application of machine learning will soon speed up drug development

Parkinson's patient can swim again after stem cell transplant

Newsweek - 14-May-2020

Study and procedure represent a milestone in personalized medicine for Parkinson's

Possible culprits in genetic diseases, cancer, and ageing found

National Institute on Aging - 14-May-2020

Research shows it could be caused by mitochondrial DNA mutations

Successful replacement of neurons lost in Parkinson's disease

Medical Xpress - 13-May-2020

New therapeutic personalized strategy could bring back movement to those suffering

Longevity in Blue Zones - key ingredients for a longer life

BBC - 13-May-2020

May be it's not just one factor but a combination of all the right factors

Prodrug reduces inflammation, restores physical function in aged mice

Lifespan.io (LEAF) - 12-May-2020

Experiments yielded promising results in efficacy, specificity, and non-toxicity

Josh Mitteldorf stakes his reputation on major rejuvenation in a mammal

Aging Matters - 11-May-2020

Imagine halving your age with 4 simple injections - at the very least it will buy more time

How to boost biological age and live longer according to experts

Irish Examiner - 11-May-2020

Feel young, live long, make the most out of our lives with these evidence-based tips

OncoSenX raises more funds for cancer therapy, plans for clinical trial

GeekWire - 11-May-2020

Allowing developments on tech that will kill cancer based on their genetics

Addressing treatment-related ageing in cancer with senolytics

Fight Aging! - 11-May-2020

Hopes are up for it to directly help the cancer research community and patients

Should WHO use a new framework for the diagnosis and treatment of age-related diseases?

Lifespan.io (LEAF) - 08-May-2020

LEAF summarises and exchange of thoughts between leading aging researchers

A potential biomarker for ventricle enlargement in the ageing brain

Medical Xpress - 07-May-2020

Detecting blood drainage lags could eventually lead to faster treatment options

LEAF interviews Dr. Ole Mensching about Apollo Health Ventures' Moonshot Venture

Lifespan.io (LEAF) - 06-May-2020

VCs are starting to recognise ageing as a problem with a massive business opportunity

LEAF interviews Daria Khaltourina about WHO classification of ageing

Lifespan.io (LEAF) - 05-May-2020

Believes life extension treatments may already exist - but need more clinical trials

What's unique in the brain functional connectivity of centenarians?

Medical Xpress - 05-May-2020

World-first research reveals how their brain adapts to ageing changes, still perform well

Pace of human biological ageing can now be measured via blood test

Columbia University Mailman School of Public Health - 05-May-2020

Can aid future trials of therapies aiming at preventing diseases and slowing ageing

Commercial glycan test kit can tell the biological age using a dry blood spot

Longevity Technology - 05-May-2020

Analysing IgG glycosylation: is it the most accurate measure of biological age?

DunedinPoAm: a speedometer that tracks the rate of ageing using methylation biomarkers

Science Daily - 05-May-2020

A simple blood test could reveal if you are ageing faster or slower than your peers

Altering macrophage epigenetics to prevent lumbar disc degeneration

Lifespan.io (LEAF) - 04-May-2020

Findings can lead future treatments for age-related conditions caused by inflammaging

Nanoparticles carrying TNF can stimulate healing of muscle ischemia

University of Illinois - 01-May-2020

Able to recover from induced surgical ischameia in hind legs of mice

Coffee clearly does something to our DNA

Food & Wine - 01-May-2020

Maybe it's good, maybe it's bad - still too early to say for sure

The integral role of gut microbiome in precision medicine

AACC (American Association for Clinical Chemistry) - 01-May-2020

Huge potential in a more personalized diagnostics and diet-based disease interventions

The simple life plan of centenarians living in Nicoya

BBC - 30-Apr-2020

Plan de Vida is to live, serve family and community

Adicet merges with resTorbio for CAR T-cell therapy pipeline funding

FierceBiotech - 30-Apr-2020

The deal moves company forward to initiating phase 1 trials in non-Hodgkin lymphoma next year

GlycanAge offers free biological age blood tests in the UK

CISION PR Newswire - 29-Apr-2020

1,000 free tests available in May - but be quick, my names already on the list!

Mapping gene expression regulation in yeast to understand ageing

Google AI Blog - 29-Apr-2020

Made possible by Calico's research expertise and Google AI's machine learning tech

Telomerase activity restored in vitro and in mice

Lifespan.io (LEAF) - 27-Apr-2020

Potential to support new therapies for dyskeratosis congenita, other age-related diseases

Discovery of molecules allowing telomere restoration

New Atlas - 26-Apr-2020

Demonstrated in mice, study paves way for treating ageing-related diseases

Refining certain drugs to be less toxic and to amplify their senolytic potential

Lifespan.io (LEAF) - 24-Apr-2020

Tested in aged mice and turns out that it can rejuvenate tissue stem cells

From the organisers for RAADFest - a free webinar - Eyes on the Prize

Coalition for Radical Life Extension - 23-Apr-2020

Will be discussing important advances in age reversal - looks interesting (and did I say FREE?!)

Protein responsible for halting heart cell division, discovered

Medical Xpress - 22-Apr-2020

Findings in mice study vital for heart cell regeneration and damage repair

Mice vision restored by reprogramming fibroblasts to photoreceptors

Lifespan.io (LEAF) - 21-Apr-2020

Important study in developing cheap and effective treatments for retinopathies

DNA alterations in rod photoreceptors, linked to age-related eye diseases

Medical Xpress - 21-Apr-2020

First study to look at DNA methylation changes as mice age and how it affects visual function

Nature to launch new journal dedicated to the broad spectrum of aging research

Nature - 21-Apr-2020

Anti-aging research is becoming main stream, because NOBODY is researching how to speed it up!

How external factors could influence Alzheimer’s disease via the gut microbiome

Lifespan.io (LEAF) - 20-Apr-2020

Early study into complex neurochemical relationship between brain, gut and inflammaging

Longevity Vision Fund joins Series B funding for Sigilon Therapeutics

Longevity Vision Fund - 20-Apr-2020

To support human clinical trial of novel encapsulated cell therapy for hemophilia A

Early life intelligence can impact physiological age and later-life health

PsyPost - 17-Apr-2020

Once again highlights the importance of early life on healthy older ageing

Metformin repairs metabolic and mitochondrial defects in myotonic dystrophy

Lifespan.io (LEAF) - 16-Apr-2020

New hope for sufferers of disorders that negatively impact metabolism

A new faster technique restores vision in mice with retinal degeneration

National Institutes of Health (NIH) - 15-Apr-2020

Researchers plan clinical trials of this in humans to treat retinal diseases

Inhibiting p38 MAPK rejuvenates resolution response in elderly

Lifespan.io (LEAF) - 15-Apr-2020

A new perspective on mitigating the effects of inflammaging, promoting health in older people

Major mouse senolytics testing experiment is go!

Lifespan.io (LEAF) - 13-Apr-2020

We'll almost certainly need a combination of drugs so look forward to seeing the results

Aerobic exercise can reverse effect of ageing on muscle stem cells

INVERSE - 13-Apr-2020

Evident in old mice, this exercise can also accelerate muscle tissue repair

Inheritance of damaging mutations decides how long we get to live

GEN News - 10-Apr-2020

With whole exome and genome sequencing we could reveal so many secrets of life

The importance of early life microbiome in gut protection

Lifespan.io (LEAF) - 10-Apr-2020

Demonstrated in neonatal mice microbiome mediating an immune response

Navitoclax improved, now a safer senolytic drug choice

Fight Aging! - 09-Apr-2020

They found efficient way to increase its senolytic specificity, reduce platelet toxicity

Stem cell transplantation repairs stroke-injured rat brains

Medical Xpress - 08-Apr-2020

New possibility on restoring injured neural circuitry in humans after stroke

Dawn til dusk fasting improves blood biomarkers

Lifespan.io (LEAF) - 08-Apr-2020

Small study (14 participants) with strict participation requirements, but interesting biomarker results

Mobility and sense of touch restored in stroke-injured rat brains

Lund University (Lunds Universitet) - 08-Apr-2020

Stem cell transplantation gives hope to humans affected by stroke

Senolytics may have the potential to treat asthma

Lifespan.io (LEAF) - 07-Apr-2020

Will senolytics become the panacea to the whole Pandora's box by 100 years into future?

Resveratrol reduced DNA double-strand breaks in mice cells

Lifespan.io (LEAF) - 06-Apr-2020

Variety of polyphenols had positive impact on genomic stability

FDA gives the green light for human trials against a new coronavirus therapy

WebMD - 03-Apr-2020

May cause serious adverse effects if stem cells over attack normal lung cells

Gut enzyme prevents age-related loss of intestinal barrier integrity

Lifespan.io (LEAF) - 03-Apr-2020

In animal models, IAP is found to prevent frailty and extend lifespan

Positive feedback look identified with ATM via NF-κB pathway back to cellular senescence

Lifespan.io (LEAF) - 02-Apr-2020

As always, it's complicated, but controlling levels of ATM could be part of a therapy to combat ageing

UK resident takes over as world's oldest man at 112

Guardian - 31-Mar-2020

He has kept active through-out his retirement and doesn't look a day over 80!

CRISPR-Cas9 variants, key to overcoming major limitation in gene editing system

Lifespan.io (LEAF) - 31-Mar-2020

Entire genome now targetable, open to interventions for use in combating diseases

Proposed strategy to protect elderly from gerolavic infections like COVID-19

Forbes - 31-Mar-2020

To benefit long term global health and longevity, and enhance economic recovery

Gut microbiota highly influenced by ageing and dietary fat intake

Lifespan.io (LEAF) - 30-Mar-2020

Several short-term responses and alterations are evident in a mice study

Injecting endothelial cells speeds up the bone healing process

Asahi - 29-Mar-2020

Injecting human endothelial cells in to animals caused blood vessels and bone tissue to grow

Mitochondrial transplants are successful but benefits are short lived

Lifespan.io (LEAF) - 25-Mar-2020

May be a solution to ageing related mitochondrial dysfunction which leads to diseases

Female of the species always outlives the males

BBC - 24-Mar-2020

Humans more equal than most species because less of an environmental effect

Yamanaka factors plus 2 more resets cells age without destroying their identity

Lifespan.io (LEAF) - 24-Mar-2020

Stanford University researchers spin out Turn Biotechnologies to develop therapies using OSKMLN

Scientists reverse cellular ageing while maintaining cell's identity

New York Times - 24-Mar-2020

How long will it take until this can be applied to human cells inside the body?

Review on the relationship between senescence and bone marrow cancer

Lifespan.io (LEAF) - 23-Mar-2020

How senescence can fuel cancer development and how malignant cells induce senescence

Healthy old-people's poo improves gut microbiome of mice

Lifespan.io (LEAF) - 20-Mar-2020

Healthy gut means healthy body. Thought there are alternative ways of increasing probiotic bacteria!

Stem cells from a 110-year-old women open doors to aging research

Phys.org - 20-Mar-2020

Scientists created stem cells from supercentenarian for the first time, calling it "super sauce"

Senescent marker levels in different tissues among different age groups

Lifespan.io (LEAF) - 19-Mar-2020

We need to recognize normal patterns in order to identify what's abnormal

Metastudy reviews impact of mitochondrial aging on cardiovascular disease

Lifespan.io (LEAF) - 18-Mar-2020

Still lots to discover, but SENS already looking at ways to stop it in its tracks

Study determines impact of lifestyle choices on expected age of death

Fight Aging! - 18-Mar-2020

Easier to understand in years, rather than percentages. Whole milk a surprisingly big factor.

Diabetic retinopathy in mice, reversed by primitive stem cells

Lifespan.io (LEAF) - 17-Mar-2020

This arrival of a more efficient stem cell type has high impact for regenerative medicine

7 COVID-19 patients recovered, owing to stem cell therapy

Lifespan.io (LEAF) - 16-Mar-2020

A small study, but a big impact on the 7 participants who all recovered quickly

Stability of splicing regulation, key to naked mole-rat longevity

Fight Aging! - 16-Mar-2020

Mechanism behind their exceptional lifespan and prolonged healthspan becoming clear

FDA issues safety alert for stool transplant after string of infections

Healio - 13-Mar-2020

Safety concerns alerted OpenBiome to recall unused materials and test donors in screening process

Growing new organs from stem cells out in the space

Independent - 10-Mar-2020

Gravity on earth spatially restricts growth of stem cells into actual 3D organs

A global commission laid out roadmap for gene-editing trials on human embryo

Wired - 09-Mar-2020

Strict ethical guidelines to avoid undesirable outcomes in gene-edited babies

Cognitive and motor function improve with mitotherapy in aged mice

Fight Aging! - 06-Mar-2020

These are among other benefits revealing new insights into anti-aging research

Fixing the genes to cure inherited blindness

Guardian - 04-Mar-2020

Crispr gene editing is a great but a dangerous tool

Cell therapy, possible gamechanger in diabetes treatment

Lifespan.io (LEAF) - 04-Mar-2020

A success in mice trial, now to move forward to larger animals then human clinical trials

Rapamycin decreased survival and longevity in mice with short telomeres

Phys.org - 03-Mar-2020

mTOR, a pro-survival pathway for shorter telomeres and inhibition is deleterious

Novel approaches to CNS diseases done by Cerevance

Longevity Technology - 03-Mar-2020

After a successful phase 1 trial of the CVN424 done one mice, the company started phase 2 studies

Unsurprising ways to increase UK life expectancy up to 5 years

The Conversation - 02-Mar-2020

Government taps doctors, scientists, and UK citizens' personal efforts to achieve this

Comprehensive history and explanation of senescent cells

The Scientist - 01-Mar-2020

Including the latest on clinical trials of first-generation senolytics

Donor supercentenarian’s cells help unlock mysteries of super-longevity

Longevity Technology - 28-Feb-2020

Evidence of cellular age reversal demonstrated in this gateway research

First cryonics site in southern hemisphere set to 2020 completion

ABC News - 26-Feb-2020

With this new build, cryonics expected to become more mainstream in the future

Why people should take up a career in the aging research industry

Lifespan.io (LEAF) - 26-Feb-2020

I think Victor is right, anti-aging is going to be the next big thing

Oisín made it to top 10 breakthrough technologies of 2020

Business Wire - 26-Feb-2020

Will begin clinical trials after completing pre-clinical studies

UK life expectancy stalls - poorest hit the hardest

BBC - 25-Feb-2020

The club fights for equality in longevity to help everyone access new rejuvenation therapies

Ethics report shows equal respect helps prepare for health emergencies

Nuffield Council on Bioethics - 24-Feb-2020

As is often the case, it's politicians who need to act before the spotlight is on them

NAD+ replenishment improves and restores fertility in women

Lifespan.io (LEAF) - 24-Feb-2020

This provides simple, safe way to rejuvenate egg cells as shown in aged mice study

Stimulating the production of stem cells done by scientists

IFL Science - 24-Feb-2020

Stimulation the production of stem cells is in direct comparison with the healing speed

Mitochondria plays a major role in cellular ageing

Medical Xpress - 20-Feb-2020

HDAC inhibitor shows beneficial effects in mice but too toxic for healthy humans

How mitochondria drives senescence, affecting healthy ageing

EurekAlert! - 20-Feb-2020

Potential target for drug-based interventions to delay cellular ageing identified

Targeting neurodegenerative disease with a novel device

Longevity Technology - 19-Feb-2020

Foundation of the new therapies mechanism is to access and control the compounds of CSF

The new quality control system that clears misfolded proteins outside cells

EurekAlert! - 18-Feb-2020

Opens new pathways for treatment of disorders such as Alzheimer's disease

Can senolytics improve heart disease and repair damaged heart cells?

European Pharmaceutical Manufacturer - 18-Feb-2020

Senescent cells seem to play a major role even in heart diseases

NMN restores neurovascular health, improves cerebral blood flow in ageing

Lifespan.io (LEAF) - 17-Feb-2020

Mitochondria-targeted interventions in old mice could be key to age-related diseases.

First gene therapy for a rare eye disease, now NHS-approved

BBC - 17-Feb-2020

This life-changing new gene therapy will halt sight loss and improve vision

Werner syndrome and normal aging epigenetic signatures differ

Fight Aging! - 17-Feb-2020

Werner syndrome, not merely accelerated normal aging as previously thought

Vladimir Radovic summaries tips from David Sinclair's Lifespan book

Health DNA - 15-Feb-2020

We should all be following Sinclair's lifestyle - if anyone knows how to live longer, he does!

Skin microbiome provides the best prediction of age

Lifespan.io (LEAF) - 14-Feb-2020

It will be more easy and convenient to take samples from skin and saliva, rather than fecal samples

LEAF interviews Hanadie Yousef, co-founder and CEO of Juvena Therapeutics

Lifespan.io (LEAF) - 11-Feb-2020

Muscle regeneration would have a huge hit on healthspan - getting people more mobile again

LEAF interviews Lewis Gruber about targeting cancer and senescent cells

Lifespan.io (LEAF) - 11-Feb-2020

Biomarker caused by glycolysis seen in all types of cancer - exciting possibilities

Creating vessels from a human yarn

IFL Science - 11-Feb-2020

Yarn helps prevent inflammation which can be caused by synthetic materials used now

New drug that fastens the bone fracture healing process

Purdue University - 11-Feb-2020

By improving the healing process the drug will reduce the life-threatening effects of bone fractures

Repletion of NAD+ has some degree of improvement on ageing in mice

Fight Aging! - 07-Feb-2020

Needs to study more on NAD+ interventions in order to achieve significant benefits

Ageing in mice - the systemic burden of senescent cells matters

Fight Aging! - 06-Feb-2020

Senescent cell burden is a marker of disease free years ahead of life

Profiling deep age using protein sequencing and analysis

Longevity Technology - 06-Feb-2020

UK residents can buy an AgeCurve sample kit and send a saliva sample

CRISPR gene editing to help immune cells target and kill cancer

New Scientist - 06-Feb-2020

First CRISPR cancer trial in the world publish its promising findings

Hyperbaric oxygen therapy's impact on cardiac function

Jerusalem Post - 04-Feb-2020

Protocols were evaluated on the patients with “normal” aging heart

Association between lung function and epigenetic age

Fight Aging! - 31-Jan-2020

Association with acceleration is strongly expressed in women above the age of 50 years

NHS warns the public about Gwyneth Paltrow and her Goop lab

Huffington Post - 30-Jan-2020

She's not a doctor or scientist, so listen to the people who are

Underlying mechanisms of how cellular senescence leads to neurodegeneration

Buck Institute - 29-Jan-2020

Cellular senescence is now a top research topic and a very messy one in ageing research

Chronic inflammation leads to inflammaging

Medical Xpress - 29-Jan-2020

If we can slow down inflammaging we may be able to achieve longevity

SASP Atlas created by team of researchers

Lifespan.io (LEAF) - 28-Jan-2020

It is a comprehensive proteomic database of soluble proteins and exosomal cargo SASP factors

New discovery showed mitochondria found living in the blood

Lifespan.io (LEAF) - 27-Jan-2020

Mitochondria living in the blood definitely has some functions, further research needed to discover

Why does our hair turn white?

BBC - 23-Jan-2020

Modulating your stress levels will help you prevent many problems, including your hair colour

Sleeping melanocyte stem cells cause greying of hair due to ageing

University of Alabama at Birmingham (UAB) - 23-Jan-2020

Further research will give us a better understanding about stem cells in general

Regrowing nerves with a biodegradable device in macaques

Futurism - 23-Jan-2020

Bridging long nerve gaps from injuries; soon to enter human trials in 2021

David Sinclair Ask Me Anything - best bits

Lifespan.io (LEAF) - 22-Jan-2020

Always interesting to hear what Dr Sinclair has to say

Polymer tube to aid peripheral nerve regeneration

EurekAlert! - 22-Jan-2020

Better than just letting the nerves grow haphazardly on their own

Fight Aging! reports back from SENS Research Foundation Pitch Day

Fight Aging! - 20-Jan-2020

When some of these succeed in human trials even more money will pile in to fund further advances

How SENS is tackling mitochondrial DNA damage

Lifespan.io (LEAF) - 17-Jan-2020

Amutha Boominathan presented her work on MitoSENS project at Ending Age-Related Diseases 2019

Inequalities in wealth leads to inequalities in healthspan

Independent - 15-Jan-2020

Access to healthcare maybe restricted in disadvantaged socioeconomic groups

4 categories of ageing identified: metabolic, liver, kidney, immune system

Lifespan.io (LEAF) - 14-Jan-2020

Knowing which ageotype you are could help focus your efforts on where you're ageing most

A chance to be resurrected in the future

The Moscow Times - 14-Jan-2020

Russian cryonics company already has 71 brains and human cadavers

Navigation using mental mind maps rejuvenated in old mice

Lifespan.io (LEAF) - 13-Jan-2020

Researchers able to teach old mice new tricks ;)

Good lifestyle adds up to 10 years to life expectancy

BBC - 09-Jan-2020

That's 10 years to find a rejuvenation therapy that adds another 10 years... and then another...

Interview with LEAF's Elena Milova

Medium - 09-Jan-2020

Education and funding are essential to enable radical life extension in the next 20 years

A human brain that persisted for 2,600 years

Live Science - 09-Jan-2020

Scientists assume that filaments in the brain played a role in the extraordinary preservation

Placental stem cell derived NK cells are effective against multiple myeloma

Myeloma Research News - 08-Jan-2020

Preliminary results from Phase 1 trial look promising

An enzyme that prolongs lifespan in roundworms discovered

INVERSE - 07-Jan-2020

Results have been replicated in cultured human cells - a new hope for life extension?

Living beyond hundreds - oldest person alive is 117

Metro - 02-Jan-2020

Supercentenarians in Japan - what is the secret behind their longevity?

Can we treat the ageing process or not? That's the question

UCSF - 02-Jan-2020

John Newman, UCSF asst prof & Buck Institute researcher, explains upcoming ageing interventions

Longevity Leaders' latest report on how longevity is disrupting the world

Longevity Leaders (LSX) - 01-Jan-2020

An interesting collection of interviews and white-papers with industry leaders

Chinese scientist tried genome editing on embryos

Guardian - 31-Dec-2019

Research of He Jiankui was a violation of medical regulations

Berberine: the new entity that slowed down ageing in mice

Fight Aging! - 26-Dec-2019

Just like rapamycin, berberine also slows down the senescent process

Cryonicists get together in New York - Reason reports back

Fight Aging! - 25-Dec-2019

No surprise there is a big overlap in interest in life extension from the cryonics community

Interdisciplinary forum on longevity urges policy rethink

Forbes - 24-Dec-2019

Good to see pressure starting to build to handle the coming fundamental changes to society

Josh Mitteldorf argues for the minority view on methylation changes

Josh Mitteldorf Blog - 23-Dec-2019

Are epigenetic changes the cause or a symptom of ageing?

Human head transplant could be possible by 2030

Independent - 22-Dec-2019

Still there will be many issues even if the spinal cord could be transplanted

Scientists identify multiple genes responsible for keeping cancer cells alive

Independent - 20-Dec-2019

If combined they can form the largest database of genetic information on cancer

Scientists discover a master regulator of cellular senescence

Medical News Today - 19-Dec-2019

Solving the mystery of ageing - still at the beginning

Autophagy may be the reason behind benefits of calorie restriction

Fight Aging! - 19-Dec-2019

Better to read on best practices of calorie restriction with optimal nutrition before you start

Brazilian researchers create "mini-livers" using human blood cells

Agência FAPESP - 18-Dec-2019

Soon it may be possible to print a liver in 90 days instead of waiting for a transplant

$85M raised by Epirium to reverse process of aging

Karma Impact - 18-Dec-2019

Company claims its technology reverses decline of mitochondrial function in aging and disease

NIH launches clinical trial to test new therapy for macular degeneration

National Institutes of Health (NIH) - 16-Dec-2019

Patient-derived induced pluripotent stem cells to replace dead retinal cells

Some stem cell products are not FDA certified

Medical News Today - 10-Dec-2019

US companies received a warning from the FDA for selling stem cell products without approval

Cost is not the decisive factor when it comes to anti-ageing products

Business Insider - 10-Dec-2019

SPF 30+ good quality sunscreen and a vitamin A based product will make you look less aged

Method of Generating Induced Pluripotent Stem Cells

Longevity Technology - 10-Dec-2019

New reprogramming technology could provide an alternate source of material needed for therapies

Big changes in blood protein levels as you turn 34, 60 and 78

New Atlas - 05-Dec-2019

Could these proteins be the culprit behind ageing?

Rapamycin causes mTOR inhibition having an impact on mammalian aging- Brian Kennedy

Lifespan.io (LEAF) - 04-Dec-2019

mTOR pathway, part of the deregulated nutrient sensing hallmark of aging

Life expectancy reduces by nearly 3 years

BBC - 02-Dec-2019

The goal to live more than 100 years seems to be slowly drifting away

The constant development of stem cell technology

GEN News - 02-Dec-2019

Gene editing and stem therapy together could bring far superior treatment methods

"Rapamycin may slow ageing in human skin" says a new study

Science Daily - 25-Nov-2019

This topical application of rapamycin did not get absorbed in to bloodstream

NIH and Gates Foundation to invest $100 million each to develop gene therapies

Time Magazine - 24-Nov-2019

New hope for the 37.9 million people worldwide living with HIV/AIDS

Human trials to test efficacy and safety of genetic introduction of telomerase

Genome Context - 23-Nov-2019

Telomeres: are we about to crack the secrets of anti-ageing

Calorie restriction can restore myelin on demyelinated nerves

Lifespan.io (LEAF) - 22-Nov-2019

Tested in mouse model - but it's a good starting point

AI and CRISPR Key to Stem Cell Use in Regenerative Medicine

FierceBiotech - 20-Nov-2019

Functional organs from stem cells possible through machine learning and gene-editing

Life expectancy increase reflected in number of older people in society

BBC - 19-Nov-2019

Even without life extension experts predict increasingly longer lives

Dr. Michael Fossel interviewed by LEAF

Lifespan.io (LEAF) - 18-Nov-2019

Fossel argues for telomerase therapy over senolytics

Long live the dogs - an attempt to increase lifespan of man's best friend

CNN - 15-Nov-2019

Dog Aging Project plans to recruit dogs from all 50 states

Could immune cells be the secret to extreme longevity?

Live Science - 15-Nov-2019

Unusually high concentrations of T helper cells found in supercentenarians bloodstream

UK life expectancy falls with biggest impact in deprived areas

Independent - 14-Nov-2019

Avoidable deaths, not medical illnesses, kill more people under 50

High levels of killer cells in the immune system of supercentenarians

Medical Xpress - 13-Nov-2019

Relatively immune to infections and cancers - also get to live more than 110 years

Ambrosia young blood plasma treatments relaunched

OneZero - 08-Nov-2019

No further clinical trials planned, but some interesting results from initial trial

Metabolism and mitochondria gene function impacted by spaceflight

New Scientist - 07-Nov-2019

Most changes reversed when back on Earth - but what about Mars microgravity?

Treating with rapamycin improves blood flow to the brain in rats

Science Daily - 06-Nov-2019

Blood circulation in the brain didn't deteriorate even a bit for 15 months

Mr Senescence explains how to speed up ageing research

Lifespan.io (LEAF) - 05-Nov-2019

Long validation times in ageing research – experimental time is a bottleneck

A bit of saliva can reveal your biological age and rate of ageing

Clinical OMICs - 04-Nov-2019

Individuals age at different rates, therefore chronological age cannot say much

A new breakthrough in the regenerative medicine

TechRadar - 04-Nov-2019

Using a fluid matrix instead of a solid support structure may be the solution of bioprinting

CRISPR technology edited plant cells after being sprayed on their leaves

New Scientist - 01-Nov-2019

Can get into animal cells, so I wonder if this could be used with humans in future?

Master Investor Magazine focuses on longevity in its Autumn edition

Master Investor - 01-Nov-2019

Interesting articles and some useful investment opportunities

Blind mole rats can prevent age-related chronic inflammation

Fight Aging! - 01-Nov-2019

They have a natural mechanism against cellular senescence and ageing

Novo Biosciences CEO talks about drug candidate for tissue regeneration

Lifespan.io (LEAF) - 29-Oct-2019

Regrowing damaged organs would help many people live longer, healthier lives

Senescent cells show cellular cannibalism in mouse and human cancer cells

Nature - 28-Oct-2019

They're often called zombie cells - and turns out they are. Time to kill them with senolytics!

Eternal searches of blood substitute

Medical Futurist - 26-Oct-2019

Donating blood could be the most useful thing for now because someone needs it every two seconds

British and Israeli teams join to reverse ageing of blood vessels

British Heart Foundation - 25-Oct-2019

British Heart Foundation working on anti-ageing research? It must be mainstream now!

Could you live longer with minimal brain activity?

Big Think - 25-Oct-2019

Gene regulation calmed high neural activity and prolonged life in mice & roundworm

Algorithms creating discrimination in the US healthcare system

Wired - 24-Oct-2019

Software guidance for patients gives privileges to white patients over black patients

Huda Suliman explains the nuances of drug discovery in ageing research

Lifespan.io (LEAF) - 23-Oct-2019

Indications are less clear with anti-ageing compounds than with disease specific drugs

Footballers have a high risk of death from neurodegenerative diseases

BBC - 22-Oct-2019

Except for neurodegenerative diseases, ex-footballers are less likely to die from other diseases

Growth Differentiation Factor 11 - beneficial effects in mouse model

Science Daily - 22-Oct-2019

Would we be able to achieve effects of lifestyle changes by just taking a pill?

OncoSenX targets solid tumours with senolytics

Lifespan.io (LEAF) - 22-Oct-2019

Phase 1 clinical trial starting early 2020

TAME Metformin Trial: An Editorial by Aubrey de Grey

Fight Aging! - 22-Oct-2019

Is it really the best use of $75M in the crusade against aging?

Prime editing as a way of "editing" genes

BBC - 21-Oct-2019

There are around 75,000 mutations caused by DNA errors and prime editing can correct 89% of them

Mice with extra-long telomeres lived longer

ScienceAlert - 21-Oct-2019

Will we be able to have a longer lifespan by lengthening our telomeres too?

Cardiac glycosides may play a role as broad spectrum senolytics

Medical Research Council London Institute of Medical Sciences - 21-Oct-2019

Is it really possible to develop a drug without side effects?

Heart drugs found to be anti-cancer

Medical Research Council London Institute of Medical Sciences - 21-Oct-2019

Many drugs for heart diseases are broad-spectrum senolytics as tested in mice

Protein misfolding ruins the young and beautiful cell

Phys.org - 17-Oct-2019

Presence of free radical damage significantly reduced the lifespan in worm model

The lowest mortality levels ever recorded

LSE (London School of Economics and Political Science) - 16-Oct-2019

Good news – recent quarterly statistics suggest that UK life expectancy is no longer stalled

LEAF Interviews the NIA's Deputy Director Dr. Ronald Kohanski

Lifespan.io (LEAF) - 16-Oct-2019

Systems biology discovers the networks that are essential for a living organism

Using dead people for artificial organ studies

Yale Daily News - 14-Oct-2019

Bioethicists developed guidelines for dead candidates selection, communication with their families

Direct cell to cell transformation without a stem cell stage

TechCrunch - 14-Oct-2019

Analyses a huge amount of data without the help of an artificial intelligence

Walking speed could be a determinating factor of ageing speed

BBC - 12-Oct-2019

People who walked slower had a worse state of lungs, teeth and immune system

Drug invented for a girl with Batten disease

BBC - 12-Oct-2019

Doctors from Boston sequenced in detail whole genome of Mila and found the disease-causing mutation

A potential genetic shield against ionizing radiation: Dsup

Fight Aging! - 11-Oct-2019

Picking up genes and proteins from other species to make a superhuman

New gene therapy to treat AMD will last a lifetime

ScienceDaily - 11-Oct-2019

A better option than having injections in to the eye once a month

Cervical cancer successfully cured with gene editing in mice

Medical Xpress - 10-Oct-2019

If the right genes to tackle are identified, this could be the cure for all cancers

Hair follicles damaged by air pollution

Independent - 09-Oct-2019

There are more serious effects of air pollution on the lungs, but one more reason to find clean air

Nanalyze looks at Insilico Medicine's AlphaGo moment in pharma

Nanalyze - 09-Oct-2019

From lab to clinic in 2 years instead of 10 would have a huge impact on health

Microbiome therapies can soon be personalized using a digestive tracker

NutraIngredients - 09-Oct-2019

Carbiotix and Food Marble partnered to correlate gut microbiome with digestive health data

Revitalizing the aged brain - research evidence in animal models

Fight Aging! - 08-Oct-2019

Will this increase the tendency towards young blood transfusion?

High levels of glucuronic acid is a biomarker of ageing

Lifespan.io (LEAF) - 07-Oct-2019

Glucuronic acid levels in the blood can be correlated with a lifespan, healthspan in humans and mice

US doctor opens online anti-ageing clinic

CNBC - 06-Oct-2019

We need proactive longevity doctors in the UK to advise on best approaches at an individual level

Is senescent cell clearance a zero sum game?

SENS Research Foundation - 06-Oct-2019

Research suggests senolytic treatments will be beneficial for at least a few decades

Life expectancy gains have slowed

BBC - 04-Oct-2019

In Japan, life expectancy gains have been bigger than in the UK in recent years

Possible future of transplantation medicine

Fight Aging! - 04-Oct-2019

LyGenesis is developing a technique for implanting cells into lymph nodes for future transplantation

Rapamycin shows a sixty percent life expectancy increase in mice model

Aging - 04-Oct-2019

Detailed history and review of current understanding of Rapamycin and longevity

Ageing and cancer linked by a complex relationship

Medical News Today - 04-Oct-2019

Does this mean that future therapies to slow down ageing may cause cancers as a side effect?

Longevity.Technology interviews Buck Institute’s President and CEO Eric Verdin

Longevity Technology - 03-Oct-2019

Includes updates on NAPA Therapeutics and BHB Therapeutics

Experimental drug reversed the fat build up in the liver

New Scientist - 02-Oct-2019

Tests done on animals suggest that CRMP reduces heart disease risk and animals didn't lose weight

Promoting in vitro angiogenesis using optoceutics

Drug Target Review - 01-Oct-2019

Visible light stimulates the formation of the new blood vessels

Combination drug therapy increased the lifespan of Drosophila

Phys.org - 30-Sep-2019

Treatment combination consists of lithium, trametinib and rapamycin

Cryonic labs hoping to bring back people in the future

Starts at 60 - 30-Sep-2019

People who want to be frozen have to pay AU$300,000 for their entire body, AU$118,000 for the brain

LEAF interviews AgeX Therapeutics CEO Dr. Michael West

Lifespan.io (LEAF) - 30-Sep-2019

May only be a few years away from implementing induced tissue regeneration in humans

Japanese researchers developed artificial blood

Asahi - 29-Sep-2019

Artificial blood has been effective in experiments on rabbits

Skin cancer survival rate up jumps 10-fold in just 10 years

BBC - 28-Sep-2019

UK doctors announce that more than half of the patients can now survive advanced melanoma

Skin-lightening creams could cause serious health problems

BBC - 28-Sep-2019

Looking good isn't worth dying for - only by creams from trusted retailers

Reason analyses a new review paper on metformin - he's not keen

Fight Aging! - 27-Sep-2019

There have been more negative results in mice than positive - surprising given the press it gets

Don't hurry to predict your longevity with biomarkers

The Scientist - 27-Sep-2019

Longevity results can be unproven and not ready in some aspects for being used in clinics

Telomere length linked to the nervous system

Medical Xpress - 26-Sep-2019

According to the study, shortening in the telomere length have reflected in our brain structure

Elise Hu uses NMN and lifestyle changes to knock 5 years off her biological age

NPR - 25-Sep-2019

Great video including rejuvenated mice inside David Sinclair's lab

3D grown exosomes shown to reduce signs of skin ageing

Lifespan.io (LEAF) - 25-Sep-2019

Could be mass produced and applied as a cream without need for needles

Lysoclear is making progress towards a cure for macular degeneration

Lifespan.io (LEAF) - 25-Sep-2019

Has cleared protein build up in vivo - has funding to develop clinical candidates

Senescent cells amplify blood clotting - now protein targets identified

Buck Institute - 24-Sep-2019

Could help tackle venous thrombosis that becomes a bigger risk with age

Nonviral gene therapy: the safer option and full of potential

Phys.org - 24-Sep-2019

Could it be used to increase the crop yield to fight against world hunger?

A mission to change the lives of 1 billion people

Telegraph - 23-Sep-2019

Life extension technology will be expensive, so it'll create inequalities between poor, rich people

Harvard associate professor looks at 5 common ageing myths

Washington Post - 20-Sep-2019

The science is changing all the time, we've still got a lot to learn

Senolytics and their impact on anti-ageing

Technology Networks - 19-Sep-2019

Once more confirmed, senolytics reduce senescent cells by that preventing their effect of ageing

Human skin exosomes repaired the sun-damaged skin cells in mice

Science Daily - 19-Sep-2019

Scientists used human dermal fibroblast cells for growing and harvesting exosomes from the skin

Small Mayo Clinic trial successfully removes senescent cells from humans

Mayo Clinic - 18-Sep-2019

Occasional senolytic use may be enough to keep senescent cells at bay

Investing in the Longevity industry

Longevity Technology - 18-Sep-2019

Edwards believes 20–30 years will be added to the average lifespan with none of the ageing diseases

16 year healthspan gap between areas in Britain

Guardian - 15-Sep-2019

Healthy life expectancy (HALE) in Blaenau Gwent, south Wales, same as Zambia

Customers report being deluded by Trusii water company

CNBC - 14-Sep-2019

Many customers left with thousands of dollars debt for the machines that didn't even work

First-in-human, FDA-approved clinical trial to test a hydrogel on cardiac tissue

Medical Xpress - 12-Sep-2019

Positive results seen in patients who had a heart attack more than a year before

Interview with Aubrey de Grey - Longevity.Technology Exclusive

Longevity Technology - 12-Sep-2019

Great intro to life extension's leading advocate - Aubrey predicts radical change within 5 years

New technology which makes reprogrammed cells a reality

USC news - 12-Sep-2019

Uncoiling DNA molecules starts the process of reprogramming

Michael West examines how to safely revive telomerase

Lifespan.io (LEAF) - 12-Sep-2019

It powers foetal development and telomere length, but also cancers

Exercising and having calorie restrictions could affect bones

News Medical - 11-Sep-2019

Mice who exercised and ate less also had a decrease in bone quantity due to the cut in calories

LEAF Interviews Dr. David Sinclair, Prof. of Genetics at Harvard Medical School

Lifespan.io (LEAF) - 10-Sep-2019

He started taking resveratrol in 2003, and now added NMN and some metformin

From cryonic baths to ozone saunas, to the search of magic pill

Wired - 10-Sep-2019

In 2018 consumers spent $43 billion on anti-ageing products according to Orbis analysis

LEAF interviews David Sinclair about NMN trials and epigenetics

Lifespan.io (LEAF) - 10-Sep-2019

He's optimistic that human trials will convert the majority of people who are skeptical or unaware

Biological age reversed with growth hormone and diabetes drugs cocktail

Nature - 05-Sep-2019

Small, uncontrolled trial, but (potentially) very exciting results

Four years of poverty triggers premature ageing

Center for Healthy Aging - University of Copenhagen - 05-Sep-2019

May not notice poorer physical and mental capabilities until it's too late

New treatment for inherited retinal dystrophies

BBC - 04-Sep-2019

Gene therapy presents injecting the healthy gene directly in the eye to produce working protein

World's first anti-ageing trial received FDA approval

Longevity Technology - 04-Sep-2019

TAME trial lead by clinician Dr Nir Barzilai will begin in November

A way to reprogram mature cells into totipotent stem cells

Asian Scientist - 03-Sep-2019

Creating totipotent stem cells opens ways for revolutionary findings in regenerative medicine

Recalibration of signalling factors to more youthful levels in the blood

Lifespan.io (LEAF) - 03-Sep-2019

Adjusting the levels of just two molecules in the blood could lead to significant rejuvenation

Senolytics - Getting rid of faulty cells in body

Guardian - 02-Sep-2019

Aims to prolong the healthspan as well as the lifespan

Treatment with immune system caused remission in incurable leukaemia

Independent - 02-Sep-2019

CAR-T therapy gives hope for the children for whom the standard therapies don't work

First cornea transplant made from ‘reprogrammed’ stem cells

Nature - 02-Sep-2019

Donors cells were adult skin cells, which have reprogrammed into an embryonic-like state

Leukocyte telomere length found to be linked to DNA methylation (DNAm)

News Medical - 02-Sep-2019

Yet more evidence that hallmarks of ageing are inter-related, not standalone actions

Tooth enamel could be repaired

Guardian - 30-Aug-2019

In human teeth, the clusters had given rise to a crystalline layer within 48 hours

Pirating a $7000 version of a million-dollar gene therapy

MIT Technology Review - 30-Aug-2019

This could be beneficial if things go well, but dangerous otherwise

Growth factor mimicking synthetic antibodies stimulate tissue regeneration

University of Toronto - 30-Aug-2019

Sounds like a potential solution that can reverse ageing and restore youth

AI guesses a person's biological age and sex using an ECG

The Register - 28-Aug-2019

Still not sure how the artificial intelligence does it though

Alternate-day fasting can help reduce belly fat and lose weight

Medical Xpress - 27-Aug-2019

ADF does not weaken our immune system like other fasting regimens do

Today's 50 year-olds may live another 100 years

Forbes - 26-Aug-2019

Good summary of some major investments in life extension companies

Nanobots - potential superheroes in the war against cancer

Sifted - 26-Aug-2019

There's a chance for at least one of these novel approaches might work

Regenerating entire organs with biomedical engineering

The University of Melbourne (Pursuit) - 25-Aug-2019

Biomedical engineering is a combination of regenerative and personalized medicine

Salk scientists developed a new genome-editing tool tested on mice

Salk Institute - 23-Aug-2019

New powerful tool is developed for targeting the non-coding areas of DNA

14 biomarkers indicate the remaining lifespan of an individual

Medical Xpress - 21-Aug-2019

Accuracy of mortality risk prediction is high when using this method

Pluripotency and telomeres, butterfly effect discovered

ScienceDaily - 20-Aug-2019

Pluripotent cells are like a black box, but they can open new doors for regenerative medicine

Caloric restriction in humans have health benefits

Irish Times - 19-Aug-2019

This method is already being used to extend the lifespan in lab animals

Gut and oral human microbiome, mapped

Science Daily - 19-Aug-2019

Study reveals links between bacterial genes and disease risk, key to future protection

Ageing related brain stem stiffness lead to dysfunction of nerve cells

Medical Xpress - 14-Aug-2019

Used brain stem cells of young and old rats for this research

Generation X notorious for drug poisoning and suicide

BBC - 13-Aug-2019

Stigma may be a reason for their reluctance to seek help

Why do some regions have many “supercentenarians” while other regions don't?

VOX - 09-Aug-2019

Poor record-keeping might be the reason why some countries have more supercentenarians than others

Reversing epigenetic changes rejuvenated mice with progeria

MIT Technology Review - 08-Aug-2019

Could turning back the clock on genes make us live much longer?

Adult neurons can grow with the help of a group of proteins

Medical Xpress - 07-Aug-2019

Potential to cure paraplegia and quadriplegia someday in the future

Chronokines in young blood could be the cure for Alzheimer's

New Atlas - 06-Aug-2019

Plasma proteins to the rescue of good-old memories in Alzheimer's

Scientists explore the mystery of immortal Hydra

New Atlas - 05-Aug-2019

May be one day we will be able to grow our limbs back

Electrical stimulation therapy to ears improved body, sleep and mood

BBC - 30-Jul-2019

Newly discovered benefit of transcutaneous electrical nerve stimulation

Human trials using CRISPR to cure genetically inherited blindness

Futurism - 30-Jul-2019

There are at least 13 types of LCA - this trial is aimed at treating LCA 10

First attempt to use CRISPR tool to treat a genetic disorder

NPR - 29-Jul-2019

Cells are being taken from patients' bone marrow and genetically modified with CRISPR

Nucleotides as a key element to cellular rejuvenation

Interesting Engineering - 28-Jul-2019

Removing senescent cells will make us vulnerable to cancer

Development of drugs that might eliminate ageing cells

ScienceDaily - 25-Jul-2019

Prevention of losing nucleotide synthesis ability would result in cells slowly ageing

Scientists restore heart function after MI in mice model

Genetic Engineering & Biotechnology News (GEN) - 24-Jul-2019

This will be the solution to post heart attack complications

Skin regeneration in mice - 2 different methods but same pathway

Lifespan.io (LEAF) - 18-Jul-2019

Retinoic acid could be a key ingredient in elixir of youth

Stem cell reactivation can improve tissue regeneration

Lifespan.io (LEAF) - 16-Jul-2019

Just one pathway out of many that could improve tissue rejuvenation

France to stop funding homeopathic care from 2021

Guardian - 10-Jul-2019

If only they’d spent the £114m last year on ageing research instead

NHS gives the green-light to a “gene-silencing” drug for the first time

BBC - 09-Jul-2019

It took thirteen years for RNA interference technology to come to this stage

Worms from ice-age era come back to life as ice melts

Futurism - 09-Jul-2019

Life forms in other planets - we could start by looking for nematodes

Cryonics and reanimation - a curse or a blessing

Forbes - 08-Jul-2019

Would we, today, allow the reanimation of someone who might reintroduce the 1918 flu or medieval plague?

Update on successful dosing of first patient CLXR-001 by Celixir

GlobeNewswire - 06-Jul-2019

Ongoing clinical trials for heart patients with cellular therapy to cure damaged heart muscles

Scientists find new ways to treat hair loss and restore hair

Medical Xpress - 25-Jun-2019

Cultured hair farms can be used to replace lost hair and to test hair growth drugs

Say hello to the life-extensionists

Guardian - 23-Jun-2019

A fair summary of who's who in life extension from a journalist who clearly isn't convinced :)

Time to focus in on health extension rather than life extension

The Atlantic - 21-Jun-2019

Longer healthspans will inevitably result in longer (and longer, and longer...) lifespans

It's time for considering drug-exercise interactions

New York Times - 19-Jun-2019

Interesting - metformin plus exercise did not have an additive effect

Metabolite found in pomegranates has anti-ageing effects

Medical Xpress - 17-Jun-2019

Urolithin A could help slow certain aging processes, improve the functioning of mitochondria

Minoxidil's potential to restore elastin - can it be more useful?

Fight Aging! - 14-Jun-2019

Needs to find minoxidil analogues that can restore elastin without side effects

Totally new pathway towards healthy ageing

Independent - 13-Jun-2019

Substance circulating in the veins of juvenile mice delayed death and kept the disease at bay

Scientists sequence wild bats’ genes for long lifespan and cancer resistance

Phys.org - 12-Jun-2019

Novel molecular targets for future ageing intervention studies

Sleep-disordered breathing affects age

Medical Daily - 10-Jun-2019

Understanding how sleep-disordered breathing affects age could lead to new anti-ageing interventions

Developmental stages of anti-ageing treatments

Next Big Future - 09-Jun-2019

Two anti-ageing treatments in phase 3 clinical trials and four in phase 2 clinical trials

Right time to adopt "anti-ageing" lifestyle

News Medical - 07-Jun-2019

Key molecular programs known to promote longevity do not last beyond midlife

Tissue engineered thymus organoids could replace thymic function

Lifespan.io (LEAF) - 05-Jun-2019

And they can be located anywhere in the body

Longer telomeres linked to reduced risk of psychiatric problems in men

Oxford University Press - 05-Jun-2019

But telomere length is not linked to overall multimorbidity

Potentially revolutionary heart attack treatment option

BBC - 04-Jun-2019

"Pumping" patch could help repair the damage caused by a heart attack

Young mouse blood can reverse declines in the brains of older mice

earth.com - 04-Jun-2019

Two proteins may be responsible for improving brain cell growth

Telomerase therapy for neurodegeneration

Lifespan.io (LEAF) - 04-Jun-2019

Telomerase gene therapy may be a potential solution for age-related neurodegenerative diseases

Research into klotho is at a very interesting point

Fight Aging! - 03-Jun-2019

Research community is littered with interesting, promising foundations for therapies to treat aging

Simple and effective treatment for restoring the sense of smell in the future

ScienceAlert - 02-Jun-2019

Using droplets of globose basal cells made able to restore the sense of smell of the mice

Cryonic suspension following assisted death-first of its kind

Gizmodo - 31-May-2019

Will there be an increased demand for assisted death?

Scientists discover rapamycin's anti-ageing mechanism

Futurity - 24-May-2019

Triggers lysosomes to degrade harmful substances that collect in ageing cells

Arguments for immortalism have to deal with atheists and religious alike

US Transhumanist Party - 23-May-2019

Transhumanism does not require humans to be a specially chosen consciousness

Purging damaged brain stem cells can improve cognition in Alzheimer’s

National Institute on Aging - 23-May-2019

Promising results in genetically altered mice with Alzheimer’s traits

Placental stem cells can regenerate damaged heart cells

New Atlas - 22-May-2019

Creating beating cells and blood vessels that could treat heart attack victims

Insilico and ARK enter a research collaboration on health-span and longevity

EurekAlert! - 22-May-2019

AI-based methods, to explore mechanisms of ageing and improving health-span

Mysterious epigenetic marks and their impact on our life

Mosaic - 21-May-2019

Yamanaka factors may be the solution for reversing age-related diseases

Direct oxidative stress on telomeres leads to faster cellular ageing

News Medical - 14-May-2019

Prevents uncontrolled cell division in cancer cells

Crispr injection could reduce chance of heart attack

Guardian - 10-May-2019

Verve Therapeutics treatment targets PCSK9 gene

Non-intrusive way of generating large quantities of stem cells

Medical Xpress - 10-May-2019

Discovery could revolutionise treatment for vascular and diabetes-related cardiovascular diseases

The Rich Have More of Everything

Forbes - 08-May-2019

Low income workers still die sooner—a lot sooner—than high income people

3D printed organ that mimics lungs

Popular Mechanics - 03-May-2019

This revolutionary model could have a major impact on organ donations

DNA analysis could put an end to the oldest person debate

The Connexion - 03-May-2019

Identifying consanguinity could be the key to solve this mystery

Environmental pollutants in household items can affect ageing

INVERSE - 02-May-2019

Reduces length of telomeres and alters mitochondrial DNA levels in cells

Elderly with poor sense of smell 30% more likely to die over 13 year study

NHS - 30-Apr-2019

Smell could be another candidate for a biological age marker

Vampire facial and its effects on the skin

Independent - 30-Apr-2019

Platelets and growth factors initiate a healing response which, over time, rejuvenates the skin

Improvements seen in Parkinson's patients given NuPlasma young blood plasma

NeurologyLive - 25-Apr-2019

50% improvement in complications of therapy, 19.2% in motor examinations and more

SIRT6 gene improves DNA repair and increases lifespans

University of Rochester - 19-Apr-2019

Could it be tweaked to be even more efficient?

Interfering with enzyme production reduces crippling pain

BBC - 13-Apr-2019

Gene silencing rather than gene therapy

New telomeres lengthening treatment - space flight!

Independent - 11-Apr-2019

Unfortunately the effect disappears after returning to Earth

We would live to 240 years based on the size of these bats

ScienceDaily - 10-Apr-2019

Vampire bats are extraordinarily long-lived for their size

Hearing loss drug triggers improvements in phase 1/2 trials

FierceBiotech - 09-Apr-2019

Restoring hearing and vision would make many people's lives significantly easier

Protein discovered that keeps skin young

Eyewitness News - 04-Apr-2019

COL17A1 protein promotes wound healing, skin regeneration, and reduces skin ageing

Dr. Campisi talks about improvements in senolytics and ageing research

Lifespan.io (LEAF) - 03-Apr-2019

Unlike cancer, you don't have to kill every senescent cell

Humacyte developing off-the-shelf engineered blood vessels

Medical Xpress - 28-Mar-2019

Scaffold is populated by patient's own blood vessels

NR boosts intestinal stem cell population in aged mice

MIT - 28-Mar-2019

Supplement has a real physical health impact too = reduced inflammation

New class of drug destroys, not just inhibits, proteins

Nature - 20-Mar-2019

Cancer targeted first, but could clear out age-related proteins in future

resTORbio Agrees Phase 3 Human Trials with FDA

Lifespan.io (LEAF) - 19-Mar-2019

If successful, drug could be available in next few years

Halfway-house stem cells may be as effective as iPSCs

Fight Aging! - 19-Mar-2019

Turn.bio testing new in vivo therapy - good results for sarcopenia in mice

IMM-AGE measures biological age of the immune system

Lifespan.io (LEAF) - 15-Mar-2019

Immunosenescence is a known factor in longevity

Gene therapy makes non-vision cells light sensitive

University of California, Berkeley - 15-Mar-2019

This would be a stunning result if repeated in humans

Reducing Inflamm-Aging by topical skin application, beneficial in chronically aged

University of California, San Francisco (UCSF) - 13-Mar-2019

Rejuvenating the skin can reverse “inflamm-aging may have profound health effects

Investigation into Liveyon-Genetech stem cell treatment problems

Independent - 12-Mar-2019

Nearly 1,000 clinics selling unregulated treatments in the US

Cryonics subscriber cremated against her wishes

THERUNDOWNLIVE - 08-Mar-2019

Any small chance of reanimation destroyed

Academy for Health and Lifespan Research Q&A with Harvard's David Sinclair

Harvard Gazette - 08-Mar-2019

Rejuvenation human trials (cell reprogramming) possible in next 2 years

Billionaires accumulating more wealth and youthfulness

Telegraph - 07-Mar-2019

Automation and longevity therapies may amplify social disparities

UK life expectancy falls 6 months in a year

Guardian - 07-Mar-2019

Over 1 year down in last 3 years - this is not good news

Samsara secures more funding for cellular rejuvenation drug research

Lifespan.io (LEAF) - 06-Mar-2019

Drugs will need to work better than the free alternative - calorie restriction

Synthetic antibodies able to target senescent cells

University of Leicester - 06-Mar-2019

nanoMIPs could improve the specificity of senolytics

Graphene scaffolds have the potential to repair bones faster

Singularity Hub - 04-Mar-2019

Already shown success in mice- could become a vital part of orthopaedic medicine

IV therapy is a waste of money, or worse

Guardian - 03-Mar-2019

Live Forever Manual rates IV therapy as "save your money"

Metformin gives diabetics longer life than non-diabetics

AGEIST - 03-Mar-2019

Great summary of the drugs history, benefits and risks

Aubrey de Grey shortens timeframe for human rejuvenation

Next Big Future - 28-Feb-2019

Once proven in mice, demand and funding will surge

Parkinson's drug delivered through port in head

BBC - 27-Feb-2019

Reversal of brain cell damage knocked 6 years off disease development

Universal stem cells avoid immune reaction in mice

Lifespan.io (LEAF) - 26-Feb-2019

Could lead to off-the-shelf stem cell therapies

Ambrosia ceases young blood plasma treatment

CNN - 19-Feb-2019

Only 2 months after starting. Calling it a medical treatment may be contravened FDA guidance.

Calorie restriction drugs may help you live longer

Fight Aging! - 15-Feb-2019

BHB therapeutics develops treatment to mimic the effects of good diet

Chemicals identified to reverse mental decline

BBC - 14-Feb-2019

Mental capacity not lost - just masked by inflammation

LEAF interviews Ichor Therapeutics CEO

Lifespan.io (LEAF) - 12-Feb-2019

$16m raided, FoxBio partnership with Juvenescence, lots going on

New academy to lobby government to combat ageing

The Boston Globe - 12-Feb-2019

Will campaign to treat ageing as a disease

An Algorithm to predict biological age from skin cells

The Pew Charitable Trusts - 08-Feb-2019

Will give insights into how biological and chronological age vary among people

Unlocking the secrets of ageing hidden in blood cells

Medical Xpress - 07-Feb-2019

Blood cells have their own agenda for ageing and other cells don't have a say in it

LEAF report from the Longevity Leaders Conference

Lifespan.io (LEAF) - 06-Feb-2019

Encouraging signs from big companies - more interviews to follow

New $100m fund wants to give us 30 years extra healthspan

FierceBiotech - 05-Feb-2019

Aiming for a market of billions of people, not just the richest

Biological age of women's brains 3 year younger than men's

Independent - 04-Feb-2019

As more people suffer from dementia, men will be affected sooner

David Sinclair's admits taking NMN, resveratrol and Metformin

Next Big Future - 01-Feb-2019

Nothing too surprising in his daily supplement regime

GrimAge can calculate the time you have left to live

Lifespan.io (LEAF) - 31-Jan-2019

Will enable faster analysis of anti-aging treatments

A new platform to identify cardiotoxic drug molecules

Scitech Europa - 28-Jan-2019

No need to wait till safety trials in humans to detect cardiotoxicity

Biomaterial scaffolds provide environment for cells to regenerate tissue

Science - 25-Jan-2019

Useful summary of trials covering orthopedics, nerve repair and vascular grafts

Human tissue regeneration possible with complete axolotl genome map

Gizmodo - 24-Jan-2019

Understanding regeneration in axolotls will be a paradigm shift for medicine

UNITY Biotechnology expands trial of osteoarthritis senolytic

UNITY Biotechnology - 22-Jan-2019

Initial results must be promising to enrol more patients at highest dosage

Mini-thymus used to produce and train T cells

Lifespan.io (LEAF) - 21-Jan-2019

Able to regenerate ageing immune system, and reduce cost of immunotherapy

World’s oldest man dies in Japan aged 113

Guardian - 20-Jan-2019

Medicine increases healthspan; only life extension technologies will increase maximum lifespan

New gene therapies having big impact

Guardian - 19-Jan-2019

Successful treatment of retinitis pigmentosa and spinal muscular atrophy

Cells of living mice rejuvenated using OSKM trigger in drinking water

Lifespan.io (LEAF) - 17-Jan-2019

More support for the SENS approach of regular maintenance to stop ageing

Gut microbiome predicts age with 4 year accuracy

Lifespan.io (LEAF) - 15-Jan-2019

It both affects and is affected by its host status

UNITY Biotechnologies Selects a New Senolytic Candidate

Lifespan.io (LEAF) - 14-Jan-2019

Very early days but good to have more senolytics in the pipeline

Senolytics for IPF human clinical trial results released

Lifespan.io (LEAF) - 07-Jan-2019

Physical improvements recorded, but pulmonary function was unchcanged

Senescent cells: short safety trial on humans successful

Science Daily - 07-Jan-2019

Next step is to go to an actual large-scale human trial

Ambrosia officially launches its young blood (plasma) therapy

Ambrosia - 28-Dec-2018

The jury is still out whether benefit is from good factors in the young blood, or diluting bad factors in the patient's old blood

Japan annual birth rate nearly half a million below death rate

Guardian - 27-Dec-2018

A stark example of how birth rate falls below in replacement level in advanced economies

Protein identified that causes aging in skin

News Medical - 27-Dec-2018

The skin is our largest organ, so reversing its aging would help the whole body

Fisetin destroys senescent cells, but safe dosage not determined yet

Lifespan.io (LEAF) - 26-Dec-2018

Includes table of fisetin content in range of fruits and vegetables

Nucleosome spacing of cell-free DNA reveals biological age

News Medical - 21-Dec-2018

Always good to find a new biomarker of aging

Oral treatment for wet age-related macular degeneration passes Phase 2a trials

CISION PR Newswire - 17-Dec-2018

Intriguing hint that this treatment may have potential for other age-related diseases

Aubrey de Grey predicts age reversal trials in 5 years

Lifespan.io (LEAF) - 13-Dec-2018

Not yet predicting the end of aging, but first generation damage repair therapies.

BioViva developing an anti-aging vaccine

Precision Vaccinations - 12-Dec-2018

Developing a virus to express several anti-aging and regenerative factors

Lifelong fitness results in a 30 years younger heart

NPR - 10-Dec-2018

We all know exercise is good for us - these biomarkers help to explain why

Lifelong exercise rewards by slowing down ageing of organs

NPR - 10-Dec-2018

The way to stay young and healthy at heart

Relative Energy Deficiency in Sport caused by under-eating

BBC - 09-Dec-2018

Athletes starving themselves causes hormone and bone problems

Irrational starving leads to RED-S in sportspeople

BBC - 09-Dec-2018

Good health should never be the cost of success in sports

Human stem cell trial sees improvment in walking and lung function

Lifespan.io (LEAF) - 07-Dec-2018

Reducing frailty allows people to keep moving and break the negative feedback cycle of aging.

An unusual request to legally change an age was declined

BBC - 03-Dec-2018

Mr Ratelband, aged 69, made headlines around the world wanting to change his birth date by 20 years

2019 SRF Summer Scholars Program - applications open now

SENS Research Foundation - 01-Dec-2018

Great opportunity to work with some of the best minds in aging research

Exercise lengthens telomeres (slows aging)

NHS - 29-Nov-2018

Endurance and interval training groups saw telomeres increase by over 3%.

Using reprogrammed stem cells for treating Parkinson's disease

Nature - 18-Nov-2018

A man in his 50s is the first of seven patients to receive the experimental therapy

Reprogrammed stem cells implanted into Parkinson’s patients

Nature - 14-Nov-2018

Implantation of induced stem cells in brains with Parkinson’s disease is showing promising results in monkeys

Patients' own cells used to engineer fully personalized tissue implants

Phys.org - 12-Nov-2018

Growing new organs from patient's own cells would slash the wait times for organ transplants

First fully personalized tissue implant

Phys.org - 12-Nov-2018

Technology allows engineering any kind of tissue implant from one small fatty tissue biopsy

Plasma NAD+ Levels Decline Significantly with Age

Lifespan.io (LEAF) - 09-Nov-2018

We still need to understand it better but NAD+ is likely to be important in slowing aging

Wearable bioreactor induced a limb regeneration

Tufts Now - 06-Nov-2018

Delivering progesterone to an amputation injury site can induce the regeneration of limbs

New study finds your genes may not influence your lifespan

Science Daily - 06-Nov-2018

Family tree data suggests hereditary genes contributed to no more than 7% of a person's lifespan

Wrong weight 'can cost four years of life'

BBC - 31-Oct-2018

Massive study confirms that being overweight dramatically shortens life expectancy

Walking again after ten years with MS

BBC - 24-Oct-2018

Hematopoietic stem cell therapy allowed a man with multiple sclerosis to walk again for the first time in 10 years

The path to an extended health span and a healthier death

MIT Technology Review - 23-Oct-2018

Still a long way to go before expanding life span

Fisetin's potential to become the first line senolytic pill

Josh Mitteldorf Blog - 23-Oct-2018

Mice fed with fisetin diets lived much longer

nanoComposix: leading the nanotechnology world by innovation

GEN News - 15-Oct-2018

Innovation is necessary to survive in the field of nanotechnology

Josh Mitteldorf thinks his and Aubrey de Grey's views are converging

Aging Matters - 08-Oct-2018

Even if signaling is fix, I suspect that there will be some damage already done that needs repairing

Life span of our ancestors same as ours today

BBC - 03-Oct-2018

If they got past the dangers of childhood, our ancestors lived almost as long as we do today

Natural product Fisetin slows aging in mice

ScienceDaily - 02-Oct-2018

Fisetin is a very common natural product that has positive effects over health and aging

Direct-to-consumer stem cell marketing in Canada

Future Medicine - 26-Sep-2018

Direct-to-costumer marketing of stem cell interventions tend to minimize risk and make bold claims without scientific support

Life expectancy progress stops in UK

BBC - 25-Sep-2018

Since 2011 living beyond 90 years old has become increasingly rarer due to still unknown reasons

What Happens When CRISPR Backfires?

Seeker - 25-Sep-2018

Recent research revealed novel problems with the CRISPR technique, delaying human trials

2018 Telomere Length Update by Liz Parrish

Bioviva Science - 24-Sep-2018

A case of muscular and cellular rejuvenation thanks to myostatin and telomerase therapies

Fujifilm to test stem cells in leukemia treatment

Nikkei - 23-Sep-2018

A company is looking to start trials for induced stem cells to fight graft vs host disease

Senolytics staves off dementia in mice

Guardian - 19-Sep-2018

Killing of senescent (aging) brain cells with an enzyme stopped the progress of dementia

Clearing out senescent cells may prevent symptoms of Alzheimer’s and Parkinson’s disease

Buck Institute - 19-Sep-2018

Alternative approaches to tau targets in neurodegenerative disorders

Crowdfunding NAD+ Mouse Lifespan Study

Lifespan.io (LEAF) - 18-Sep-2018

This project aims to observe if the NAD+ precursor has a positive effect over aging mice

Wounds Healed With Reprogrammed Skin Cells

Singularity Hub - 14-Sep-2018

A topical solution converts cells from wounds into skin to repair tissue without scarring

Scientists reversed ageing by inhibiting gene pathways

Drug Target Review - 14-Sep-2018

Findings could enhance the treatments to reverse dementia or destroy cancer cells

Genes for longevity in Galápagos tortoises

Newsweek - 12-Sep-2018

All these genes couldn't save them from human hunters

Genes responsible for Galápagos Tortoise's longevity

Newsweek - 12-Sep-2018

All this to become the longest living beings on Earth and maybe more

Molecule has anti-aging effects on vascular system

Medical Xpress - 10-Sep-2018

β-Hydroxybutyrate and OCT4 slow down vascular aging, preventing disease

Elevian raises $5.5 million in seed funding

MIT Technology Review - 06-Sep-2018

Investigating ability of GDF11 to rejuvenate the body

NAD+ Repletion Shows Potential Against Aging

Lifespan.io (LEAF) - 05-Sep-2018

The precursor NMN has some rejuvenating effects over mice's metabolism and gene stability

First iPS Cell Trial for Heart Disease Soon

The Scientist - 31-Aug-2018

Researchers plan to implant induced stem cell-sheets on the heart to regenerate injured areas

Telomerase Gene Therapy Does Not Increase Cancer Risk

Lifespan.io (LEAF) - 27-Aug-2018

New research proves telomerase therapy's safety by making its effects within the cell temporary

Drug approved as alternative method to CRISPR

Singularity Hub - 21-Aug-2018

Patisiran is a new drug capable of silencing genes based on RNA interference technology

Aging focused biotechs forms AI based joint venture

FierceBiotech - 14-Aug-2018

Groundbreaking research biotechs performs aging research together for longevity

UK among worst for life expectancy rises

BBC - 07-Aug-2018

Life expectancy rises in the UK have stagnated due to still unknown reasons

Cellular aging halted by hydrogen sulfide gas

Medical News Today - 07-Aug-2018

3 compounds designed to deliver minute amounts of hydrogen to mitochondria inhibit cellular aging

Protein Patterns of Ill Health

The Scientist - 02-Aug-2018

A new study founds patterns of molecules that help predict disease and survival in elderly people

Induced pluripotent stem cells to treat Parkinson's disease

Japan Times - 30-Jul-2018

There is a risk of developing brain tumours according to some experts

Stem cell reservoir found in teeth

CGTN Live - 26-Jul-2018

Harvesting stem cells from teeth may be the key to make treatments more affordable

Mini Brains Grown in a Dish

Labiotech - 25-Jul-2018

These small organoids are being used to study Glioblastoma (brain cancer) safely

Caution Regarding CRISPR Gene Therapies

Singularity Hub - 23-Jul-2018

Newly found lack of precision of CRISPR delays plans for human trials

Can Aging Genes Be Altered by a Face Cream?

vogue - 21-Jul-2018

A French company claims to have a cream capable to reprogram skin cells

8 Types of Robotic Surgery Being Used Today

Nanalyze - 20-Jul-2018

Brief description of available robotic surgery procedures and their corresponding equipment

Telomere loop structure more important than length

Medical Xpress - 20-Jul-2018

Telomere structure rather than length may be the key to prevent aging

FoxBio is developing small molecule drugs to target ageing diseases

Business Wire - 12-Jul-2018

Antoxerene partners with Juvenescence to discover drugs that clear senescent cells

Doctors Repair Infants’ Damaged Hearts With Mitochondria

Futurism - 10-Jul-2018

Procedure transplants mitochondria into infant’s muscle cells to prevent heart disease

Cleara Biotech Joins the Race to Develop Senolytic Therapies

Lifespan.io (LEAF) - 09-Jul-2018

This therapy uses a modified FOXO4 to promote apoptosis in senescent cells

Oral senolytics have big impact on old mice

Mayo Clinic - 09-Jul-2018

Senolytic cocktail caused improved physical condition of elderly mice

Mortality rate flattens among the oldest of the old

New York Times - 28-Jun-2018

After 105 mortality rate rise more slowly and it may be related to better genes and lifestyle

Naked Mole Rats Repair DNA Super Efficiently

Fight Aging! - 27-Jun-2018

These rats seem to be almost immune to cancer for unknown reasons

Interview with OneSkin Technologies CEO

Thrive Global - 25-Jun-2018

Skin replication will allow for better quality aging research

UNITY Treats First Patient with UBX0101

UNITY Biotechnology - 25-Jun-2018

The company is going to test a new Senolytic drug in human trials

Gene that triggers senescence identified

University at Buffalo - 22-Jun-2018

The gene for CD36 becomes more active in older cells and it may be key for the aging process

Precursor cells identified in spinal cord repair

Medical Xpress - 22-Jun-2018

Confocal microscopy was used to record stem cells repairing a severe injury in Zebra fish

Gene therapy reverses rat's paralysis

BBC - 14-Jun-2018

Study used virus to deliver genetic information that reduced scar tissue in the spinal cord

What are skin serums?

Harvard Health Publishing - 12-Jun-2018

Skin serums are being used by more women as a way to fight aging

UK biotech company focused on developing anti-ageing therapies

PMLiVE - 12-Jun-2018

LyGenesis seeks to use a patient’s own lymph nodes as bioreactors to grow functioning ectopic organs

Reversing aging by removing wrinkles inside our cells

ScienceDaily - 29-May-2018

Virus-based treatment seeks to smooth cellular wrinkles in livers

Low-calorie diet prevents age-related molecular changes

Medical Xpress - 25-May-2018

Short-term diets may accelerate the manifestation of aging symptoms

Size Of Nucleolus Might Predict Lifespan

INVERSE - 21-May-2018

A smaller nucleolus may be a good indicator for aging

Alcor Receives $5 Million Donation

Fight Aging! - 17-May-2018

Donation came from a private individual involved with cryptocurrencies

XPO1 inhibition increases autophagy and lifespan

News Medical - 16-May-2018

This treatment could be used to alleviate neurodegeneration and disease progression

Potential new cure found for baldness

BBC - 09-May-2018

Osteoporosis drug had a dramatic effect on hair follicles in the lab.

FDA Clamps Down on Unapproved Stem Cell Therapies

New York Times - 09-May-2018

FDA seeking court orders to stop two stem cell clinics.

Stealthy Harvard startup wants to reverse aging

MIT Technology Review - 09-May-2018

Rejuvenate Bio is cofounded by George Church of Harvard Medical School.

Young blood as a key to living longer

Wired - 09-May-2018

GDF11 is a protein in the blood, which can stimulate cell growth and repair

AstraZeneca Partners For Stem Cell Cardiovascular Therapy

Genetic Engineering & Biotechnology News (GEN) - 07-May-2018

AstraZeneca will develop cardiovascular and catheter-based therapies.

Can autophagy boost your health?

BBC - 06-May-2018

Autophagy is the process by which cells degrade and recycle their components.

Freezing stem cells in hope of extending life

CNBC - 05-May-2018

Forever Labs extracts and stores young adults' stem cells.

Why Does Hair Turn Gray? Scientists May Know

Newsweek - 04-May-2018

Melanocytes make melanin which gives our hair its colour.

LEAF interviews Dr. Nichola Conlon

Lifespan.io (LEAF) - 03-May-2018

Look forward to seeing the results of the NAD supplement trial

Cibinetide Shows Promising Signs in Anti-Aging

CISION PR Newswire - 02-May-2018

Cibinetide works via activating the body's innate repair receptor (IRR)

The science of cryopreserving the human body

Phys.org - 24-Apr-2018

Animals produce a antifreeze proteins to prevent cell damaage.

Human Trial of Mitochondrially Targeted Antioxidant MitoQ

Fight Aging! - 20-Apr-2018

Aortic stiffness was lower in participants with elevated baseline levels.

Most millionaires expect to reach 100

YAHOO! - 20-Apr-2018

Wealth enables them to live a healthier life.

Aging Looks Are Not Just a Matter of Aesthetics

Lifespan.io (LEAF) - 19-Apr-2018

Old people tend to have grey hair, wrinkled skin, and weak muscles.

More education is what makes people live longer

New Scientist - 18-Apr-2018

Economists previously concluded that wealth itself increases longevity.

CR Leads to Longer Life but Less Grey Matter

Genetic Engineering & Biotechnology News (GEN) - 05-Apr-2018

New study shows caloric restriction in lemurs extended lifespan up to 50%.

Red coral can live for five hundred years

National Geographic - 31-Mar-2018

Coral living in deeper waters have longer lives.

Using AI to Predict Biological Age

Genetic Engineering & Biotechnology News (GEN) - 30-Mar-2018

Physical activity data from wearables can produce digital biomarkers of aging.

Men could live as long as women by 2030s

Independent - 27-Mar-2018

Currenlty across the world women experience longer life spans than men.

Scientist slow aging in mice — are humans next?

New York Post - 23-Mar-2018

Molecule reactivates faltering blood flow in elderly mice.

World’s First Commercial iPSC Cell Plant Opens

The Scientist - 23-Mar-2018

Will produce cells derived from iPS cells for commercial applications.

Major Biological Difference Between Generations

ScienceAlert - 22-Mar-2018

We seem to be ageing more slowly than we were two decades ago.

Undoing Aging 2018: an initiative to remember

Long Long Life - 22-Mar-2018

45 speakers, scientists and entrepreneurs, presented their work.

Reduced-?calorie diet slows ageing in people

Nature - 22-Mar-2018

CALERIE multi-centre trial tested 200 healthy, non-obese adults over 2 years.

5 Countries Where People Live the Longest

National Geographic - 20-Mar-2018

Here are some secrets we can learn from the countries where people live the longest.

Macular degeneration reversed with stem cell treatment

BBC - 19-Mar-2018

Major step towards curing age-related macular degeneration.

Telomerase: Downgraded by long term proponent

Josh Mitteldorf Blog - 19-Mar-2018

Josh Mitteldorf curbs his enthusiasm based on latest study.

Living ever longer without physical limitations

CBS - 19-Mar-2018

By the year 2040, people can expect to live 4 years longer in good health.

Why NAD+ Declines With Age

Lifespan.io (LEAF) - 19-Mar-2018

Nicotinamide adenine dinucleotide is a vital component of cellular function.

Silicon Valley and rich people invest to slow down ageing and live longer

This Is Money - 17-Mar-2018

All the money in the world to fight ageing and death

Gene Therapies to Greatly Reduce the Incidence of Cardiovascular Disease

Fight Aging! - 09-Mar-2018

Gene therapy could disable genes that sustain levels of lipids in the bloodstream.

Immunethep seeks funding to take its novel bacteria vaccine into clinical trials

Labiotech - 09-Mar-2018

Alexander Burik sensibly advises caution about any new type of treatment

Harvard’s David Sinclair Treats Aging as a Disease

W Xpress - 07-Mar-2018

WuXi interviews Harvard University’s David Sinclair

Pay-to-participate young-blood transfusion clinical trial

STAT - 02-Mar-2018

Bill Faloon inviting people to join a pay-to-participate clinical trial.

Self funded trial offers 'young blood' to live longer & healthier

STAT - 02-Mar-2018

Shows how promoters aggressively market unproven yet costly therapies

Deprivation reduces life expectancy by nearly a decade

Independent - 01-Mar-2018

Office for National Statistics says life expectancy of most deprived males is 73.9 years.

A massive study of family trees finds no gene for longevity

MIT Technology Review - 01-Mar-2018

Birth and death dates of more than 86 million people compared.

Obesity paradox debunked

Northwestern University - 01-Mar-2018

Previous findings showed that overweight people diagnosed with CVD live longer.

CRISPR Toolkit Expands With Trio of New Tricks

Singularity Hub - 27-Feb-2018

New CRISPR technologies are CAMERA, DETECTR, and SHERLOCK.

Your Pee May Reveal Your True Biological Age

Live Science - 27-Feb-2018

Natural chemical in urine appears in higher concentrations as we age.

Motherhood Causes 11 Years of Telomere Shortening

ScienceAlert - 26-Feb-2018

DNA collected from nearly 2,000 reproductive-age women.

Bionic larynx sounds more natural than artificial voice boxes

Digital Trends - 26-Feb-2018

MARCS Institute has demonstrated a groundbreaking noninvasive artificial larynx.

CR improves intestinal-tissue regeneration after injury

News Medical - 22-Feb-2018

Research pinpoints the cell responsible for improved regenerative abilities in the intestines.

Living Human Intestinal Lining recreated On Chip

Medical Xpress - 16-Feb-2018

Microengineered Intestine-Chips mirror living tissue.

Peter Diamandis launches new $250 million stem cells company

TechCrunch - 15-Feb-2018

Celularity is a spinout from Celgene, a global biopharmaceutical company.

Rich v poor life expectancy gap widening in the UK

Verdict - 15-Feb-2018

Boys born in prosperous neighbourhoods will live 8.4 years longer than those from a poor area.

Summary of 800 Page State of Longevity Research Report

Singularity Hub - 14-Feb-2018

Report produced by Biogerontology Research Foundation, Deep Knowledge Life Sciences, Aging Analytics Agency, and Longevity.International.

Gene in Worms Could Be Key to Longer Human Lifespan

The Cornell Daily Sun - 13-Feb-2018

Disabling the SET-26 gene’s function increased lifespan by nearly 20%.

Recent Advances in Regenerative Medicine

Fight Aging! - 09-Feb-2018

Progressing towards the ability to build complex tissues from a cell sample.

Long-Lived Bats Have Telomeres That Don't Shorten

INVERSE - 07-Feb-2018

These mouse-sized mammals live way longer than they should.

Practical hair regeneration technology

Phys.org - 02-Feb-2018

New method for the mass preparation of hair follicle germs (HFGs).

Telomeres Do Not Translate Into A Younger Biologic Age

Institute For Aging Research - 31-Jan-2018

TERT is a subunit of the enzyme telomerase.

Scientists use the patient’s own ear cartilage cells to form a new one

Independent - 31-Jan-2018

First time ever in the regenerative medicine, children receive new ears grown from their own cells.

Carbiotix offers low-cost, personalized gut health testing service

NutraIngredients - 25-Jan-2018

New microbiome test kit provides customizable supplement dosing to fill the fibre gap

Calico proves that naked mole-rats do not age

eLife Sciences - 24-Jan-2018

Possible hints where they are focusing their research

DanBrit acquires Enochian Biopharm to expand its immunotherapy pipeline

CISION PR Newswire - 23-Jan-2018

Will rebrand as Enochian and also move to Los Angeles

Inhibition of ageing maybe the solution for Alzheimer's

The San Diego Union-Tribune - 19-Jan-2018

Will be successful than drugs targeting specific aspects of Alzheimer's

Life expectancy plummets in parts of UK

Independent - 18-Jan-2018

By 2041, women will live to 86.2 years and men 83.4 years.

Could Filtering Our Aged Blood Keep us Young?

Lifespan.io (LEAF) - 18-Jan-2018

Interview with Dr. Irina Conboy of Berkeley University.

How to grow functioning human muscles from stem cells

Kurzweil Network - 10-Jan-2018

Duke University has grown the first functioning human skeletal muscle from iPSCs.

Molecule could revert cellular ageing

University of Lisbon - 08-Jan-2018

Non-coding RNA is never translated into protein.

Society for Regenerative Medicine Manufacturing Formed

Digital Journal - 08-Jan-2018

Inaugural meeting will take place during the World Stem Cell Summit.

MCP-1 A Potential Aging Biomarker

Lifespan.io (LEAF) - 08-Jan-2018

Reliable and fast ways to assess biological age are needed to determine the outcome of potential interventions.

Alpha-2-Macroglobulin in the Cancer Immunity of Naked Mole-Rats

Fight Aging! - 08-Jan-2018

Naked mole-rats are near immune to cancer.

US life expectancy falls for second consecutive year

Independent - 07-Jan-2018

A new study released by the US National Centre for Health Statistics (NCHS) found an American baby born in 2016 can expect to live 78.6 years.

Cell biology hacked to create complex shapes that form living tissue

Kurzweil Network - 05-Jan-2018

3D cell-patterning shapes active mouse and human embryonic cells into thin layers of extracellular matrix fibers.

Aging Research Half a Lifetime Ago: the Lost Decades of the 20th Century

Fight Aging! - 02-Jan-2018

AgeX Identifies Genes Implicated in Regeneration and Cancer

Business Wire - 02-Jan-2018

Study that reveals genes implicated in tissue regeneration, cancer, and aging.

US life expectancy down for a second year

USA Today - 21-Dec-2017

Health researcher claim that Americans are dying younger, and life expectancy is now down for the second straight year — something not seen in more than half a century.

Mitochondrial Contribution to Aging and Age-Related Disease

Fight Aging! - 21-Dec-2017

Mitochondria are primarily responsible for generating chemical energy stores.

Escape from senescence boosts tumour growth

Nature - 20-Dec-2017

Senescence is usually thought to be irreversible.

Curing the incurable with regenerative medicine

The News Minute - 15-Dec-2017

Multiple Sclerosis (MS) patient regains ability to walk with stem cell therapy.

Haemophilia A gene therapy results 'mind-blowing'

BBC - 14-Dec-2017

Haemophilia prevents production of a protein needed to stop bleeding.

Good work ethic could lead to a longer life

Independent - 13-Dec-2017

Mental and physical health levels of a group of Italians between the ages of 90 and 101 have been examined and found that there were many common psychological traits between them.

Young Plasma Improves Cell Recycling in Old Rats

Fight Aging! - 11-Dec-2017

Injections of blood plasma from young rats improved autophagy and liver function in old rats.

Microbiome analysis: some gut bacteria reduces inflammation

Guardian - 09-Dec-2017

Village peasant microbiome has low risk for atherosclerosis, obesity, diabetes and colitis

Boosting Mitochondrial Quality Control to Combat Alzheimer's

Lifespan.io (LEAF) - 08-Dec-2017

Diseases like Alzheimer’s are the result of the loss of proteostasis.

Key to Diseases in Mitochondrial DNA Mutations

Longevity Facts - 06-Dec-2017

DNA sequences between mitochondria inside a single cell are vastly different.

Race to create body parts in the lab

Guardian - 05-Dec-2017

Decellurised scaffold is basted in patient stem cells, called mesoangioblasts.

SRF has made progress in the fight against ageing

Lifespan.io (LEAF) - 05-Dec-2017

R&D phase in SENS repair approach has shown promising results

Pol III enzyme shows anti-aging potential

New Atlas - 04-Dec-2017

RNA polymerase III (Pol III) is an enzyme essential for cell growth.

Gene Therapies as a Basis to Control Aging

Fight Aging! - 04-Dec-2017

In principle, a gene therapy can do everything a drug can.

Cataract Surgery May Prolong Your Life

New York Times - 04-Dec-2017

60 percent lower risk of death each year if cataracts removed.

BGRF & Oxford University launch The Longevity Podcast

EurekAlert! - 30-Nov-2017

The Biogerontology Research Foundation announces the launch of The Longevity Podcast, a podcast produced in partnership with the Oxford University Scientific Society.

Glasgow has UK's highest death rate

Belfast Telegraph - 27-Nov-2017

Glasgow has topped the list of places with the highest mortality rate in the UK, new data has revealed.

Virgin birth stem cells tested for first time

New Scientist - 27-Nov-2017

“Virgin birth” stem cells come from unfertilised eggs.

People nowadays live longer, but in poorer health

Guardian - 24-Nov-2017

Adults are spending an increasing number of their retirement years in poor health

Evidence Against a Late Life Mortality Plateau

Fight Aging! - 23-Nov-2017

Mortality rates seen to flatten out in flies and other short-lived species.

People who own dogs may live longer

The Verge - 17-Nov-2017

3.4 million Swedish people monitor over 12 years.

Rare Gene for Long Life Found in Amish Community

INVERSE - 17-Nov-2017

Amish people have lived in relative isolation since migrating from Europe.

FDA Target Rogue Gene Therapy Clinics

New York Times - 16-Nov-2017

FDA issued new guidelines for expedited review of stem cell and gene therapies.

Aging tests yield varying results

ScienceDaily - 15-Nov-2017

1,000 people studied extensively from birth to age 38.

First ever attempt at gene editing inside the body

Guardian - 15-Nov-2017

Patient lacks a gene that makes an enzyme that breaks down certain carbohydrates.

Loophole Might Allow Cryogenic Freezing While Alive

IFL Science - 14-Nov-2017

Human cryogenics is legal in some countries, but you have to be dead first.

Creating a Life-Saving Industry – Regenerative Manufacturing

Industry Week - 13-Nov-2017

Dean Kamen's early inventions include the first wearable infusion pump.

Switzerland’s men no longer living the longest

Le News - 12-Nov-2017

According to the OECD last years report Switzerland tied with Iceland has the longest male life expectancy.

Why Some People Age Faster Than Others

Newsweek - 11-Nov-2017

Genetic pathway identified that may regulate the rate at which we age.

Anti-aging breakthrough could extend healthspan by making old cells young again

New Atlas - 08-Nov-2017

Instead of clearing out senescent cells scientists have found a way to rejuvenate them.

Genetically modified skin in life-saving treatment

BBC - 08-Nov-2017

Junctional epidermolysis bullosa DNA lacks the instructions to stick epidermis to the dermis.

17 new genes linked to longer lifespan identified

Times Now News - 08-Nov-2017

A team of researchers have discovered 17 new genes linked to longer lifespan, which they say could one day be targeted to help prolong human life.

Is Immortality Possible? It is for some animals

Lifespan.io (LEAF) - 07-Nov-2017

Some animals are in a state of negligible senescence.

Scientists decipher mechanisms underlying the biology of aging

Phys.org - 02-Nov-2017

Used a combination of engineering, computer science and biology to analyze molecular processes.

Young blood does little to reverse Alzheimer’s in first test

Science Magazine - 01-Nov-2017

16 people with mild or moderate Alzheimer’s disease received weekly injections of young plasma.

‘USC Longevity’ app predicts how long you’ll live

Korea Biomed - 31-Oct-2017

USC researchers have developed a mobile application that will predict how long you’ll live.

Mass-produced cardiac muscle cells brought closer to reality

Asahi - 26-Oct-2017

Keio University team piled 10 layers of iPS cell culture plates each measuring 20 x 30 cm.

Prenatal pollution exposure linked to decreased telomere length

2 Minute Medicine - 25-Oct-2017

Telomeres are short stretches of DNA are the ends of chromosomes and are essential for fidelity of genetic information during cell division.

Protein Signalling Implicated in Age-Related Hair Graying

Fight Aging! - 25-Oct-2017

Hair follicle undergoes repetitive cyclic regeneration.

Three-fold difference in mortality rates by occupation

BBC - 24-Oct-2017

A Glasgow University study found people who work in factories and in construction have higher death rates than doctors and teachers.

To stay young, kill zombie cells

Nature - 24-Oct-2017

Proof-of-concept trials starting that pit senolytic drugs against a range of age-related ailments.

Brain Stem Cell Injections Slow Ageing In Mice

Sciencr - 24-Oct-2017

Natural stem cell loss in hypothalamus was closely correlated with ageing changes.

Lifespan linked by study to mutations and lifestyle

Bio News - 23-Oct-2017

Meta study combines genetic, lifestyle and family data from 600,000 people.

Childhood poverty may up pregnant woman's biological age

Business Standard - 17-Oct-2017

Researchers at The Ohio State University in the US examined blood from pregnant women to evaluate the length of telomeres. Shorter telomeres mean an older cellular age.

Stem Cell Transplants Trialed for Age-Related Frailty

Fight Aging! - 17-Oct-2017

Mesenchymal stem cells grown and engineered for transplantation with minimal risk.

Scientists uncover changes in mRNA expression with ageing

Wiley Online Library - 17-Oct-2017

Accelerated ageing increases all-cause mortality at a molecular level

Swedes and Italians to swap lives for three months for a study into longevity

The Local - 16-Oct-2017

Around 200 residents of the Swedish city of Malmö will live with host families in Cilento on Italy’s southeastern coast, while the same number of Italians will relocate to Malmö.

Few more pounds take away few months from your life

Men's Health - 13-Oct-2017

Diet and exercise can reduce weight and improve life expectancy

Scientists unlock genes linked to organ regeneration in sea cucumbers

GenomeWeb - 12-Oct-2017

Regenerative abilities to be used in medical applications in the future

New Type of Stem Cells Could Lead to New Treatments

Futurism - 11-Oct-2017

Researchers create Expanded Potential Stem Cells (EPSCs) in mice.

Healthy 90-years-olds have same gut microbiome as 30-year-olds

EurekAlert! - 11-Oct-2017

Researchers at Lawson Health Research Institute and Tianyi Health Science Institute studied the gut bacteria in a cohort of more than 1,000 Chinese individuals in a variety of age-ranges from 3 to over 100 years-old .

How your blood may predict your future health

Guardian - 10-Oct-2017

Can predict life expectancy with reasonable accuracy based on diet, exercise, smoking and alcohol habits.

Is Aging a Gut Instinct?

Lifespan.io (LEAF) - 10-Oct-2017

Initial source of age-related inflammation could be gut microbiota.

Body-on-a-chip includes heart, liver and lung organoids

Kurzweil Network - 09-Oct-2017

Heart and liver toxicity is a major reason for drug candidate failures and drug recalls.

Esthetic and efficient revolutionary cornea implant

Business Wire - 06-Oct-2017

A nanotechnology-based solution to bring new hope to millions of blind and visually-impaired

Charlatans threaten stem cell research with unproven cures

Guardian - 04-Oct-2017

Stem cell research, or regenerative medicine, has great potential and has already delivered some breakthroughs, but its future is threatened by poor science, unrealistic hopes, unclear funding models and unscrupulous private clinics, they say in the Lance

Rejuvenating the Thymus to Prevent Age-related Diseases

Lifespan.io (LEAF) - 04-Oct-2017

<p>Thymus gland produces the majority of body's T cells. </p>

Death rate rise linked to longer stays in hospital

Guardian - 02-Oct-2017

1 in 5 of the extra deaths in 2014-15 may be attributable being stuck in hospital.

Mini-kidneys grown in lab reveal renal disease secrets

Medical Xpress - 02-Oct-2017

PKD mini-kidneys grown in free-floating conditions formed hollow cysts that were very large.

Scientists develop a chip that can regenerate damaged tissue

Scientific American - 29-Sep-2017

Can it convert only specific target cells?

Human Pancreas Reveals Signatures of Aging

Cell - 28-Sep-2017

Accumulated genetic and epigenetic errors eventually lead to impaired organ function.

Centenarians are fastest growing age group in UK

Guardian - 27-Sep-2017

Centenarians are the fastest growing age group in the UK, with the number of 100-year-olds almost doubling over a 14-year period.

Gap between men's and women's life expectancy no longer closing

Telegraph - 27-Sep-2017

The gap has narrowed every year for the past decade.

Immune System Critical to Tissue Regeneration

Lifespan.io (LEAF) - 21-Sep-2017

Study in salamanders finds heart tissue regeneration depends on presence of macrophages.

Interview with regenerative medicine RepliCel’s CEO

Digital Journal - 21-Sep-2017

Regenerative medicine is a game-changing area of medicine. It has the potential to fully heal damaged tissues and organs.

Owls hold secret to ageless ears

BBC - 20-Sep-2017

Birds are protected from age-related hearing loss. These are able to naturally repair damage to the inner ear.

Alcor Cryopreservation Charges Unchanged

Alcor - 19-Sep-2017

Annual Meeting agreed to leave minimums 2011 levels.

How death has changed over 100 years in Britain

Guardian - 18-Sep-2017

Some interesting graphs on distribution of deaths by age.

Age At First Period Could Determine Life Expectancy

Marie Claire - 17-Sep-2017

The Women’s Health Initiative collected data from 16,000 post-menopausal women.

SRF to develop glucosepane-cleaving antibodies with Spiegel Lab

Lifespan.io (LEAF) - 17-Sep-2017

Anti-glucosepane antibodies may offer new therapies for age-related diseases

Human Transplant Organs Should Be As Common As Cell Phones

Newsweek - 16-Sep-2017

Joseph Vacanti one of the authors of “The Vacanti Mouse” - a mouse with a human ear on its back reveals details about that story two decades later.

Mechanism Behind Calorie Restriction and Lengthened Lifespan Uncovered

Temple Health - 14-Sep-2017

Epigenetic drift occurs more rapidly in monkeys than in humans.

It is quite possible to slow aging and extend life span

Bio Spectrum - 13-Sep-2017

Interesting interview with Prof Brian Kennedy appointed to lead ongoing efforts at the National University of Singapore.

Anti-Aging Pilot Studies Announced

Lifespan.io (LEAF) - 12-Sep-2017

Non-profit Betterhumans known for its work in the transhumanist community announced its intention to begin small-scale trials of senolytic therapies.

Lab-grown bone cell breakthrough

STV News - 12-Sep-2017

Nanokicking used to grow 3D samples of mineralised bone for the first time.

High-intensity interval training (HIIT) Can Slow Aging

Care2 - 11-Sep-2017

Recent research has shown that high-intensity interval training (HIIT) may actually reduce and reverse longterm damage done to mitochondria—the powerhouse of the cell.

UK falls behind rest of Europe for life expectancy growth

Guardian - 10-Sep-2017

Sir Michael Marmot the author of a report on health inequality claims that UK risked becoming the “sick man and woman of Europe”.

Ilia Stambler Publishes New Text on Longevity Promotion

Institute for Ethics and Emerging Technologies (IEET) - 10-Sep-2017

Book considers the multidisciplinary aspects of longevity promotion

Direct correlation between telomere length and heart failure found

Medical Xpress - 07-Sep-2017

Study used human heart tissue samples from organ donors and heart transplants patients.

Biologists slow ageing process in fruit flies

IB Times - 07-Sep-2017

As people age, their mitochondria often become damaged - damaging the cells where any build-up occurs.

The first senolytic drugs to target senescent cells

Mayo Clinic - 05-Sep-2017

New platform will help to identify additional drugs that target ageing processes more quickly

Nucleolus is a life expectancy predictor

Phys.org - 31-Aug-2017

The nucleolus is a major structure in a cell's nucleus responsilbe for ribosome biogenesis.

FDA Cracks Down on Stem Cell Clinics

New York Times - 28-Aug-2017

The F.D.A. reported actions against two large stem cell clinics and a biotech company calling them “unscrupulous actors” in regenerative medicine.

Josh Mitteldorf argues against long telomeres causing cancer

Josh Mitteldorf Blog - 23-Aug-2017

Major new study argues that longer telomeres increase risk of cancer five-fold.

Indoles In Bowel Responsible For Longer Healthier Lives

Medical Research - 22-Aug-2017

Study into role of microbiota (bacteria inside and on body) on health span of animals.

Forever Labs will bank your stem cells for future use

Digital Trends - 19-Aug-2017

The number and therapeutic quality of our stem cells diminishes with age.

False Positives in Senescent Cell Detection

Lifespan.io (LEAF) - 19-Aug-2017

Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and ?-galactosidase biomarkers.

Scientists remove retroviral DNA from pig's genetic code

Independent - 10-Aug-2017

Possible to breed pigs to harvest their organs to meet the demand for new tissue

Klotho hormone shows promise as a cognitive enhancer

Scientific American - 08-Aug-2017

Klotho injections improved memory and motor skills of mice

Frequently Asked Questions on the Ethics of Life Extension

Institute for Ethics and Emerging Technologies (IEET) - 06-Aug-2017

Can be classified into three groups

Do moisturisers really work?

BBC - 03-Aug-2017

Moisturisers do help by supplying water to the skin and trapping it there.

Epimorphy Sells "My DNAge" Biological Age Kit

The Scientist - 02-Aug-2017

Based on an epigenetic clock origianlly developed by Steve Horvath in 2013.

Research holds Promise for Future Clinical Therapies to Slow Aging

Next Big Future - 01-Aug-2017

Cells from children with progeria studied.

Humans may take on new forms through prosthetics or genetic engineering

Daily Mail - 31-Jul-2017

NBIC technologies: Rise to possibilities for the domain of science fiction

Stem cell brain implants could slow ageing

Guardian - 26-Jul-2017

Implanted stem cells that make fresh neurons in the brain.

British billionaire gambles on an anti-aging upstart

Endpoints News - 26-Jul-2017

We are at an inflection point for the treatment of aging.

Reducing Inflammation Enhances Tissue Regeneration in Stem Cell Therapies

Lifespan.io (LEAF) - 22-Jul-2017

With aging the immune response becomes deregulated and inflammation becomes excessive.

Healthy Lifestyle May Increase Lifespan by 7 Years

Medscape - 20-Jul-2017

People who never smoked cigarettes, were not obese and drank alcohol in moderation had life expectancy of 87 years instead of 80.

Sea worms may live to over 1000 years old

New Scientist - 20-Jul-2017

Tube worm Escarpia laminata live between 1000 and 3300 metres below sea level.

Rises in UK life expectancy levelling off

BBC - 18-Jul-2017

Life expectancy has been rising for decades, but has recently slowed.

Could age related muscle loss be preventable?

Fight Aging! - 18-Jul-2017

Sarcopenia is a significant contribution to the frailty of later aging.

New method to accurately determine functional age of cells

News Medical - 11-Jul-2017

Considers biophysical qualities of cells, such as cell movements and structural features.

400-year-old sharks could hold the secret to long life

iNews - 05-Jul-2017

Greenland sharks are the longest living vertebrate on the planet.

No Known Limit To How Long Humans Can Live

Time - 28-Jun-2017

Paper in last year's Nature human body and brain petered out around 115.

14 places where life expectancy is unusually high

Telegraph - 26-Jun-2017

Villages and islands where people live into their 90s more often than average.

Global Foundation for Human Aging Research Donates $50K Harvard Medical School

CISION PR Newswire - 21-Jun-2017

Sinclair Lab studies the processes that drive aging and age-related diseases.

Scientists Discover a Key to a Longer Life in Male DNA

New York Times - 16-Jun-2017

Growth hormone receptors is linked to an increase in life span of about 10 years among men.

Living Forever

Proto - 13-Jun-2017

Review of current thinking from the Massachusetts General Hospital - the largest teaching hospital of Harvard Medical School.

Breakthrough for the generation of fully functional skin tissue

Next Big Future - 09-Jun-2017

SkinTE regenerated full-thickness, organized skin and hair follicles in third degree burn wounds.

BioTime's CEO: Human Aging Will Soon Become a Thing of the Past

Mauldin Economics - 06-Jun-2017

Cells become dysfunctional or die with aging.

Peter Diamandis - Longevity Escape Velocity

Aging Reversed - 06-Jun-2017

Interesting interview with Peter Diamandis - founder of the X Prize Foundation and Singularity University.

Young blood reduces ageing biomarkers in humans

New Scientist - 31-May-2017

Update on Ambrosia trial that gives blood plasma from under 25s to older people.

Common Antioxidant Could Slow Symptoms of Aging in Human Skin

College of Computer, Mathematical, and Natural Sciences (CMNS) - 30-May-2017

Methylene blue improved physical, biochemical and genetic aging markers.

Treating Diseases with a Protein Missile System

Lifespan.io (LEAF) - 26-May-2017

University of Dundee demonstrate AdPROM to target and destroy specific proteins within cells.

Patient uses fat stem cells to repair his wrist

CNN - 22-May-2017

Patient had no cartilage in wrist so joint was bone-on-bone and constantly inflamed.

Planning Your Own Trial of Senolytic Drugs

Fight Aging! - 22-May-2017

A guide for anyone considering self-experimentation.

Lab-Grown Blood Stem Cells Produced at Last

Scientific American - 18-May-2017

One team reprogrammed skin cell derived iPS cells with seven transcription factors.

Treating Osteoarthritis by Removing Senescent Cells

Lifespan.io (LEAF) - 03-May-2017

Researchers used local clearance of senescent cells (in mice) to reduce the development of post-traumatic osteoarthritis and encourage tissue regeneration.

Repairing Mitochondrial DNA for Age-related Diseases

Lifespan.io (LEAF) - 02-May-2017

University of Sheffield has made progress in repairing the damage done to mitochondrial DNA (mtDNA).

Researchers discover how protein aggregation triggers aging

News Medical - 21-Apr-2017

The insulin receptor acts like a brake on life expectancy.

Naked mole rat can survive with hardly any oxygen

New Scientist - 20-Apr-2017

Long-lived for its size and rarely gets cancer.

Ageing is a Disease. Gene Therapy Could be the Cure

WIRED - 20-Apr-2017

Most age related diseases are a symptom of cellular malfunction.

Cord blood rejuvenates old brains

New Scientist - 19-Apr-2017

Researchers inject mice with blood plasma from humans of different ages – babies, 22 and 66 years old.

Artificial Thymus to Create Cancer-Fighting Cells

UCLA - 10-Apr-2017

T-cells mature within this gland.

Prolonging Life with Fecal Transplants

Josh Mitteldorf Blog - 10-Apr-2017

Middle-aged fish receiving a transplant of gut bacteria from young fish had in increased mean lifespan of 41%.

Is This the Anti-Aging Pill We’ve All Been Waiting For?

MIT Technology Review - 28-Mar-2017

Novartis sought to see whether giving low doses of everolimus to people over 65 increased their response to flu vaccines.

Hallmark of Aging Reversed by Senescent Cell Removal

Lifespan.io (LEAF) - 25-Mar-2017

Study directly targets one of the mechanisms that senescent cells use to avoid apoptosis,

Old blood can be made young again

New Scientist - 22-Mar-2017

Protein boosts blood stem cells, making them behave like those of younger people.

New Form of Stem-Cell Engineering Raises Ethical Questions

New York Times - 21-Mar-2017

Synthetic embryos could be assembled from stem cells that can organize themselves into embryolike structures.

Having children could increase your lifespan

Independent - 17-Mar-2017

Once you reach the age of 60, men and women live longer if they have at least one child.

New protein discovered in aging and cancer

Medical Xpress - 07-Mar-2017

Study describes a new way that senescent cells communicate via the expression of integrin membrane proteins.

Gene therapy cures boy of sickle cell disease

New Scientist - 01-Mar-2017

People with sickle cell disease make abnormal versions of haemoglobin – distorting red blood cells into a sickle-shape that can get stuck in blood vessels.

Why do taller humans die younger?

Phys.org - 01-Mar-2017

Of the 10 tallest people ever recorded, the oldest died at 56.

Fir extract could have anti-cancer and anti-aging properties

Medical Xpress - 28-Feb-2017

Effects of Siberian fir terpenoids on senescent and human cancer cell lines studied at the genetic level.

Induced Pluripotency to Enable Rejuvenation of Blood Production

Fight Aging! - 23-Feb-2017

Induced pluripotency appears to produce a form of cellular rejuvenation.

Stem cells collected from fat may have use in anti-aging treatments

EurekAlert! - 17-Feb-2017

Adult stem cells collected directly from human fat are more stable than other cells.

Exciting Therapy To Treat Age Related Blindness Moving To The Clinic

Lifespan.io (LEAF) - 15-Feb-2017

Ichor Therapeutics is a biotechnology company focused on developing drugs for age-related diseases.

Scientists create first 3-D synchronized-beating heart tissue

Kurzweil Network - 08-Feb-2017

York University has created in vitro 3D heart tissue made from three different types of cardiac cells.

Half-century old misconception removes limits on life extension

EurekAlert! - 07-Feb-2017

Strehler-Mildvan (SM) correlation was reported in 1960.

Induced pluripotent stem cells don’t increase genetic mutations

ScienceDaily - 07-Feb-2017

iPSCs treatments have been slowed by concerns that these cells are prone to increased numbers of genetic mutations.

Life expectancy: 120,000 numbers in just four minutes

BBC - 07-Feb-2017

Fascinating data visualisation of life expectancy for 200 countries over 200 years.

First Fruits of Research with Young Blood Plasma

Josh Mitteldorf Blog - 23-Jan-2017

Mix of proteins in your blood is characteristic of your age.

Can We Reverse Aging With young blood?

Dan’s Plan - 20-Jan-2017

Interview with Drs. Michael and Irina Conboy of the Department of Bioengineering at UC Berkeley.

Forget blood transfusions, the fountain of youth could be closer to hand

Lifespan.io (LEAF) - 18-Jan-2017

Attempts have been made to rejuvenate the body by transfusing old people with young blood.

Calorie restriction extends life of monkeys by 3 years

New Scientist - 17-Jan-2017

Trial in macaques has found that CR makes them live 3 years longer than normal – equivalent to 9 years in people.

Scientists Discover Master Regulator of Cellular Aging

Scripps Research Institute - 12-Jan-2017

Newly discovered a protein, named TZAP, binds the ends of chromosomes.

Science-Backed Therapy Targeting Senescent Cells May Be Future Anti-Aging Serum

Medical Daily - 11-Jan-2017

Growing older results in a build-up of the body’s senescent cells and naturally accumulate with age.

Stem cell research offers new hope of restoring sight

Medical News Today - 11-Jan-2017

End-stage retinal degeneration (e.g. age-related macular degeneration, retinitis pigmentosais) is the most common cause of irreversible vision loss and blindness in older adults.

Qatar leading ‘ambitious’ genome project in Gulf

Gulf Times - 06-Jan-2017

Qatar Genome Programme (QGP) focuses on mapping the population as well as treating common and rare diseases.

Ray Kurzweil talks about Physical Immortality

Aging Reversed - 03-Jan-2017

Ray talks about the singularity, AI and human hybrid thinking with neocortex connected to the cloud.

Anti-aging therapies targeting senescent cells: Facts and fiction

Cell - 29-Dec-2016

Peter de Keizer of the Erasmus University Medical Center discusses strategy of removing senescent cells.

A Look at Ascendance Biomedical, Packaging Medical Tourism for Longevity Therapies

Fight Aging! - 28-Dec-2016

It is focused on the twofold path of

Programming Stem Cells to Repair or Regenerate Damaged Cells

A4M - 20-Dec-2016

Scientists from Penn State have uncovered the cellular mechanisms that control the programming of the stem cells.

Anti-ageing breakthrough: Reprogramming the body could extend lifespan

Independent - 15-Dec-2016

Previous attempts resulted in younger cells but the mice developed tumours.

Possible way to stop activation of proteins known to cause age-related diseases

News Medical - 15-Dec-2016

Scientists have discovered that it is possible to stop the activation of a group of proteins – NADPH Oxidase.

Looking Back and Ahead in the Use of Pluripotent Stem Cells in Medicine

Fight Aging! - 14-Dec-2016

Therapies that deliver fresh new stem cell populations will take up the work of lost cells, e.g. muscle cells in order to reduce frailty.

Targeting Senescent Cells with Synthetic Biology

Lifespan.io (LEAF) - 09-Dec-2016

CellAge is going to develop synthetic promoters which are specific to senescent cells, as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies.

RNA splicing could help us prevent aging

Futurism - 06-Dec-2016

Researchers wanted to find out the impact of RNA splicing on the ageing process

Fight Aging predicts the sequence of arrival for meaningful antiaging therapies

Next Big Future - 01-Dec-2016

Each treatment will target a different type of molecular damage in cells and tissues.

Bringing cryopreserved corpses back to life - fiction or reality?

The Conversation - 01-Dec-2016

So as for now it's still not possible to revive those who are cryopreserved

Figures Show 20-Year Gap Between Healthy Life Expectancy Across UK

Huffington Post - 30-Nov-2016

Male healthspan varies from 54 years in Tower Hamlets, London, to 71.8 years in Rutland, East Midlands.

DNA repair and metabolism as determinants of species longevity

eLife Sciences - 22-Nov-2016

Mammalian lifespan differs by >100-fold

Scientists to ‘reset’ blood proteins in attempt to slow ageing process

Guardian - 22-Nov-2016

Participants will have their blood passed through a machine that resets abnormal levels of proteins seen in older blood.

First-time birth in later life may increase longevity

Medical News Today - 18-Nov-2016

Average age of American mothers has increased from 24.9 years in 2000 to 26.3 years in 2014.

Removing mutated DNA from mitochondria to turn back the aging clock

Caltech - 18-Nov-2016

Hundreds to thousands of mitochondria per cell each carrying its own mtDNA.

76 year old lady signed up to be cryogenically preserved

BBC - 18-Nov-2016

Costs around £28,000 for whole body cryonic suspension

Eating a well aged cheese could help you live longer

Business Insider - 15-Nov-2016

Research published in Nature Medicine finds the compound spermidine improves cardiovascular health.

Community ‘Well-Being’ Helps You Live Longer

WebMD - 10-Nov-2016

People in more contented U.S. counties lived an extra two years or more.

END OF DEATH says leading researcher

Express - 01-Nov-2016

Aubrey de Grey speaking at technological Inman Connect conference.

Boosting levels of antioxidant may help resist age-related decline

Kurzweil Network - 28-Oct-2016

Glutathione helps resist the toxic stresses of everyday life – levels decline with age.

This start-up believes it can slow the aging process

Washington Post - 28-Oct-2016

Unity Biotechnology’s technology jump starts senescent cells into dividing again.

Scientists discover elixir of youth

Independent - 27-Oct-2016

Natural compound, called NMN, found in avocado, broccoli, cucumber, cabbage and edamame has remarkable anti-ageing effects in mice.

CRISPR Gene Editing Cures Mice of Sickle Cell Disease

Futurism - 12-Oct-2016

CRISPR used to correct mutated hematopoietic stem cells.

Young ovaries rejuvenate older mice and extend their lifespan

New Scientist - 11-Oct-2016

Swapping an older mouse’s ovaries for young ones reversed the effects of ageing on the immune system and metabolism.

Our Complicated Relationship to Longevity

LARB - 04-Oct-2016

Book review: Cracking the Aging Code by Josh Mitteldorf, Dorion Sagan

Fears of ageing may cause earlier death

Medical Xpress - 29-Sep-2016

World Health Organization quote research that people who hold negative views about their own ageing do not recover as well from disability and live on average 7.5 years less than people with positive attitudes.

Record number of centenarians in UK

BBC - 29-Sep-2016

Number of people aged 100, or over, has quadrupled over the last two decades.

Epigenetic clock predicts life expectancy

United Press International - 28-Sep-2016

Study led UCLA analyzed over 13,000 blood samples.

Clinical research seeks fountain of youth

Japan News - 15-Sep-2016

Keio University running a human trial orally administered nicotinamide mononucleotide (NMN).

Stem cell tourism may end your life

Labiotech - 08-Sep-2016

Desperate patients are ready to do everything to access to new treatments.

Proclara Biosciences raised $47 million funding to advance treatment for neurodegenerative diseases

Business Wire - 07-Sep-2016

Relaunches as a clinical-stage company, with phase 1 clinical trials of lead compound for Alzheimer’s

Poor Correlation Between Telomere Length and Health

Fight Aging! - 02-Sep-2016

Telomeric DNA decreases with age and when they get too short cells self-destruct or become senescent.

Heavy Isotopes and Slowed Aging

Fight Aging! - 01-Sep-2016

Raising short-lived species on a low dosage of heavy water appears to modestly slow aging.

Life extending drug tested on dogs

Deccan Chronicle - 15-Aug-2016

Anti-rejection drug rapamycin extend the life of mice by more than 25 per cent.

Bookworms Have Better Life Expectancy

Pharmacy Times - 09-Aug-2016

Reading patterns of 3635 patients aged 50 and older studied.

Young blood antiaging trial raises questions

Science - 01-Aug-2016

Ambrosia (https://www.ambrosiaplasma.com/) young plasma trial is open to anyone 35 and older.

3D Bioprinter Make Artificial Bones From Scratch (VIDEO)

Singularity Hub - 08-Jul-2016

New Aether bioprinter aiming to be fraction of cost of existing biological 3D printers.

Fat cells may be used to grow human bones

Futurism - 28-Jun-2016

Could be superior to old school reconstructive procedures

Increase in disability-free life expectancy

ScienceDaily - 06-Jun-2016

Difference in life expectancy for a 65-year-old:

Target Genes for Slowing Aging

Fight Aging! - 06-Jun-2016

75 potential targets for gene therapy in the near future.

Scenarios for the future of healthy life extension

London Futurists - 25-May-2016

Talk by London Futurists chair David Wood discussing:

Telomere Length Does Not Predict Atherosclerosis Risk

Fight Aging! - 25-May-2016

Epidemiological studies have demonstrated shorter leukocyte telomere length (LTL) in patients suffering coronary artery disease, heart attack or stroke.

Aging not inevitable for sea urchins

MDI Biological Laboratory - 24-May-2016

Sea urchins can quickly regrow damaged spines and feet.

Advance praise for The abolition of aging

David Wood Blog - 23-May-2016

Due out in June – looking forward to reading this well researched book.

Animated GIF: 100 years of global aging

VOX - 20-May-2016

Today median age ranges from 18.5 years in Cameroon to 46.5 years in Japan.

Interview: Research and database director of Gerontology Research Group

VICE - 20-May-2016

Gerontologist Robert Young talks about maximum human lifespan.

Twins more likely to live to retirement

New Scientist - 18-May-2016

Identical twins are less likely to die young from unexpected causes.

Nicotinamide riboside (NR) stops the aging process in organs

Kurzweil Network - 06-May-2016

EPFL researchers restore ability of mice organs to regenerate – also extending life.

Life expectancy gap between rich and poor widens in UK

Independent - 03-May-2016

First time gap has increased for 150 years.

Secret of youthful looks in ginger gene

BBC - 29-Apr-2016

DNA mutations that protect the body from UV radiation can also lead to red hair.

No stem cells required

Science Daily - 28-Apr-2016

Gladstone Institutes has used chemicals to transform human skin cells into heart cells.

Visceral Fat Tissue Will Kill You

Fight Aging! - 11-Apr-2016

Visceral fat is the fat around the organs, rather than under the skin (subcutaneous fat).

Dental Fillings Heal Teeth With Stem Cells

Newsweek - 07-Apr-2016

New filling stimulates stem cells to encourage the growth of dentin — the bony material that makes up the majority of the tooth.

Eating less may lead to longer life

Irish Times - 07-Apr-2016

Greater longevity for those who reduce their calorie intake.

Stem-cell repair system can regenerate any kind of human tissue

Kurzweil Network - 06-Apr-2016

Able to regenerate any tissue damaged by injury, disease, or aging.

Lab-grown skin sprouts hair and grows glands

BBC - 01-Apr-2016

Took cells from gums and converted them into induced pluripotent stem cells (iPSCs).

Two common gene variants reduce life expectancy by 3 years

ScienceAlert - 01-Apr-2016

University of Edinburgh researchers analysed genetic information from more than 152,000 people in UK Biobank study.

Good education adds a decade to life expectancy

Newsweek - 22-Mar-2016

Life expectancy of college-educated white men 11.9 years longer than their low-educated counterparts.

Pharmacological Extension of Lifespan

Institute for Ethics and Emerging Technologies (IEET) - 04-Mar-2016

Sample chapter from Maria Konovalenko’s Longevity Cookbook.

Impatient People Likely To Age Faster

Tech Times - 24-Feb-2016

Shorter telomeres discovered in impatient subjects.

Scientist declares homeopathy a "therapeutic dead-end"

Independent - 19-Feb-2016

Eye-opening results for homeopathy clients - ineffective as a treatment method

Rapidly Building Arteries that Produce Biochemical Signals

Duke University - 18-Feb-2016

Reproduce signalling between cell layers within arterial walls (endothelium and media).

Doctors 3D-print ‘living’ body parts

BBC - 16-Feb-2016

Sections of bone, muscle and cartilage all functioned normally when implanted into animals

Why people in Iceland outlast the rest of the world

Today - 16-Feb-2016

Iceland is one of the top-ranked countries for life expectancy.

3D-printing a new lifelike liver tissue for drug screening

Kurzweil Network - 15-Feb-2016

Closely mimics the human liver’s sophisticated structure and function.

Over-65s in England living longer than ever before

BBC - 12-Feb-2016

Latest figures released by Public Health England.

Why rich people live longer

New York Times - 12-Feb-2016

Longevity gap between high-income and low-income Americans has been widening sharply.

Naked Mole Rats Do Get Cancer

Longevity Reporter - 10-Feb-2016

Naked mole rats can live up to 30 years, making them the longest living rodents.

New procedure wins Brain Preservation Prize

Kurzweil Network - 09-Feb-2016

21st Century Medicine team has won the Small Mammal Brain Preservation Prize and get about £18,000.

Artificial trachea pioneer reinvestigated

The Scientist - 05-Feb-2016

Paolo Macchiarini is again facing an investigation into his research practices.

Mitochondria trigger cell aging

Medical Xpress - 04-Feb-2016

Probably only 1 of many aging factors at cellular level – but every little helps as reducing aging a little buys a few more years for science to reduce it even more.

Clearing the Body’s Retired Cells Slows Aging and Extends Life

The Atlantic - 03-Feb-2016

Cells accumulate damage in their DNA.

Lifespan Machine studies random variation in worm death (VIDEO)

STAT - 02-Feb-2016

Fascinating video of analysis of differences in lifespan of identical organisms.

Algorithm Predict How To Grow Any Cell Type

Longevity Reporter - 30-Jan-2016

Direct reprogramming signals a cell to morph straight into another cell type.

Most Realistic Lab-Grown Liver Tissue Yet

Futurism - 29-Jan-2016

Human cells taken from a real liver used to construct a microfluidics-based tissue.

Mechanotherapy regenerates injured muscle tissue

Kurzweil Network - 28-Jan-2016

Could replace or enhance drug- and cell-based regenerative treatments.

American Ants That Never Get Old

Smithsonian - 21-Jan-2016

Pheidole dentata don’t show any signs of aging.

Do Current Stem Cell Therapies Produce Rejuvenation?

Fight Aging! - 20-Jan-2016

Therapies available in clinics vary in type and quality of cells used.

Nobel scientist thinks we can live to 150

Telegraph - 20-Jan-2016

Dr Elizabeth Blackburn won the Nobel Prize in 2009 for research on telomeres and the genetics of ageing.

Radical Life Extension can be Developed Quickly for the Mainstream

Institute for Ethics and Emerging Technologies (IEET) - 07-Jan-2016

Interview with Didier Coeurnelle – cochair of Heales, board of International Longevity Alliance (ILA) and lifelong member of Longecity.

Could mRNA Overtake all other Biologicals in Medicine?

Labiotech - 05-Jan-2016

What if we could send the body an instruction to produce its own drug?

Are We Hitting A Life Expectancy Plateau?

Longevity Reporter - 04-Jan-2016

Average lifespans may be rising maximum years are unchanged.

Genes that help you live to 100

New Scientist - 30-Dec-2015

Searching the genomes of centenarians these genes are most clearly associated with lifespan.

Meet the animal that may live forever

The Avenue Mail - 27-Dec-2015

Tiny hydra – a centimetre-long polyp that inhabits fresh water all over the world – does not show any sign of deteriorating with age.

Metformin, Gamma Rays or Chocolate?

Institute for Ethics and Emerging Technologies (IEET) - 26-Dec-2015

Brian Hanley discusses the safety of metformin aging clinical trial.

Indian startup grows human liver in lab

The Hindu - 23-Dec-2015

Pandorum Technologies has developed an artificial tissue that performs the functions of the human liver.

Spit test could predict life expectancy

University of Birmingham - 23-Dec-2015

Lower levels of antibodies in saliva are associated with of an elevated risk of mortality.

$1m prize to first team to create a fully functioning replacement liver

New Organ - 13-Dec-2015

The New Organ Liver Prize will award $1,000,000 to the first team that creates a regenerative or bioengineered solution that keeps a large animal alive for 90 days without native liver function.

Life expectancy: Is the party over?

BBC - 11-Dec-2015

Higher than expected death rates among older people in 2012 and 2013.

Metformin human trials planned

Diabetes.co.uk - 30-Nov-2015

Could significantly increase life expectancy and health span.

100 orgasms may increase life expectancy by three to eight years

Women’s Weekly - 26-Nov-2015

Article says based on “latest research” – I’ve not checked it but, hey, it’s a Friday story!

How Long Will You Live?

Veritasium - 25-Nov-2015

Great video introduction to one of the causes of aging – telemere length v cancer inducing telemerase.

Higher pulse equals higher risk of death

Telegraph - 23-Nov-2015

Risk of dying increases by around nine per cent for every extra 10 beats per minute

Want to Live Forever? What It Costs to Get a Shot at It

MoneyTalksNews - 20-Nov-2015

Cryonics – the practice of preserving people then reanimating them at some future date.

Functional vocal-cord tissue grown in lab

Kurzweil Network - 19-Nov-2015

Cells grown from mucosa then applied to 3D collagen scaffold.

Study Links Daily Coffee Habit To Longevity

NPR - 16-Nov-2015

Study highlights association, not causation.

Telomeres naturally shorten each time DNA is copied in preparation for cell division

Kurzweil Network - 13-Nov-2015

Shortened telomeres have been implicated in aging and disease.

Consumer 3D printer used to create human tissue (VIDEO)

BBC - 28-Oct-2015

Researchers from Carnegie Mellon University develop new method to print soft materials – such as collagens, alginates and fibrins.

Can we extend our lifespan, one gene at a time?

Genetic Literacy Project - 27-Oct-2015

There are definitely environmental factors that influence longevity as well as genetic ones.

Youthful bone marrow transplants increases lifespan in mice

Fight Aging! - 27-Oct-2015

Mice received bone marrow transplants from young donors every 3 months from age 6 months.

First induced pluripotent stem cells 3D printer

The Herald - 21-Oct-2015

Able to print extremely delicate iPS cells in three dimensions without damaging their biological functions.

Switching off genes could extend lifespan by 60 per cent

Sydney Morning Herald - 12-Oct-2015

238 genes identified that, when silenced, increase the lifespan of yeast cells.

Dutch cyclists have longer lives

BBC - 11-Oct-2015

University of Utrecht finds that cycling 74 minutes per week increases life expectancy by 6 months.

Gene-editing record could enable xenotransplants

Nature - 06-Oct-2015

Harvard Medical School use CRISPR/Cas9 gene-editing technology to inactivate 62 porcine endogenous retroviruses (PERVs) in pig embryos. Ten times more edits than in any other animal.

Schoolchildren could be working until they’re 100

Telegraph - 06-Oct-2015

Rohit Talwar of Fast Future will be addressing nearly 300 headteachers at the Headmasters’ and Headmistresses’ Conference.

Could jellyfish help find a formula for immortality?

BBC Earth - 04-Oct-2015

Turritopsis nutricula jellyfish studied.

Harvard professor believes anti-aging pill is only a few years away

Sydney Morning Herald - 03-Oct-2015

If the greatest driver of disease in old age is old age itself, then why not find a cure for ageing.

Seven Emerging Technologies That Will Change the World Forever

Institute for Ethics and Emerging Technologies (IEET) - 29-Sep-2015

Researchers gave the mice a compound called nicotinamide adenine dinucleotide or NAD for a week and found that the age indicators in two-year-old mice were restored to that of six-month-old mice. That would be like turning a 60-year-old human into a 20-ye

Self assembling biological tissue-like material grown in lab

Queen Mary University of London - 28-Sep-2015

QMUL create materials using peptides and proteins that self-assemble to form a dynamic tissue.

Lab-grown kidneys work in animals

BBC - 22-Sep-2015

Jikei University School of Medicine in Tokyo grew kidneys, drainage tube and bladder from pig and rat stem cells.

3D-printed guide helps regenerate complex nerves

Kurzweil Network - 18-Sep-2015

Regrowth of nerves after injury or disease is very rare.

Secret to old age health could lie in purging worn-out cells

New Scientist - 16-Sep-2015

Cells eventually stop dividing to replace damaged neighbours and to into senescence.

Work stress can have massive impact on life expectancy

Behavioral Science & Policy Association - 08-Sep-2015

Meta-study carried out by Harvard Business School and Stanford University analyzed 228 different studies.

Investigating the Mechanisms of Remyelination

Fight Aging! - 07-Sep-2015

As well as diseases such as multiple sclerosis everyone suffers demyelination as part of aging.

Test shows how old your body really is

BBC - 07-Sep-2015

Biological age determined from signature of 150 genes’ behaviour.

Ouro_botics developing build affordable modular bioprinter

Irish Tech News - 01-Sep-2015

10 micron accuracy bioprinting platform that can be fitted with different types of extruder heads.

Stem Cell Transplants Extend Life in Rats

Fight Aging! - 31-Aug-2015

Monthly intravenous stem cells transplantations extend life span of rats by 31.3%.

Live 4 years get 1 free!

Japan Times - 28-Aug-2015

Average life expectancy around the world has increased from 65 years in 1990 to 71.5 years in 2013. So for every 4 years lived your life expectancy increases by 1 year – when those figures are the same everyone is living forever!

Rejuvenation Biotechnology 2015 : Thoughts on Thymus Regeneration

Fight Aging! - 24-Aug-2015

Regeneration of the thymus is one of a number of possible ways to introduce much larger numbers of fresh new immune cells into an old body,

Weak doses of radiation prolong life of female flies

Medical Xpress - 24-Aug-2015

Hormesis, where moderate stress has a stimulating effect on an organism and enables the prolongation of life, was first discovered in 1888. This study with weak doses of gamma radiation prolonged the life of fruit flies by 5%.

Alpha lipoic acid lengthens telomeres

Emory University - 20-Aug-2015

Dietary supplement alpha lipoic acid (ALA) can stimulate telomerase, the enzyme that lengthens telomeres, which could have positive effects on chronic diseases such as atherosclerosis and diabetes. ALA is present in many foods and counteracts high-fat-die

Life expectancy gap between rich and poor reduced in UK

Guardian - 11-Aug-2015

People in the richest 10% of UK live 4.4 years longer compared to those in the poorest 10% areas. Results in 2010 reduced significantly from 2003 study when gap was 6.9 years.

Genetic switch starts aging in animals

ScienceDaily - 23-Jul-2015

Worm signals to itself to turn off cell tissues protective mechanisms, precisely at the onset of reproductive maturity, starting the decline of the adult animal. Happens over course of hours. Genetic switch is target for future research.

Rokit enters 3D bioprinting race

3DPrint.com - 22-Jul-2015

The manufacturer of the 3Dison range of desktop 3D printers has announced a $3 million government grant with the aim of having a 3D bioprinter working on-site at the Seoul National University Bundang Hospital within 3 years. Initial focus will be bioprint

Artificial liver alternative to transplant

ScienceDaily - 17-Jul-2015

Spheroid Reservoir Bioartificial Liver (SRBAL) successfully tested in pigs. Healthy hepatocytes reduce severity of liver disease. Over 30,000 people die from liver failure each year in the US alone.

Axons grown across chronic spinal cord injury (SCI)

Kurzweil Network - 17-Jul-2015

Deleting PTEN gene in mice neurons stimulated growth of axons across damaged nerve up to 1 year after the original injury.

Gene therapy restores hearing in deaf mice

Kurzweil Network - 13-Jul-2015

Targeted delivery of functioning TMC1 gene to hair cells in cochlea using engineered virus AAV1.

Metformin seeks approval for first life extension drug trial

City AM - 09-Jul-2015

Existing diabetes drug has been show to delay aging so researchers are now applying to the US Food and Drug Administration (FDA) to run a human trial (Targeting Aging with Metformin, or TAME). Would set precedent for anti-ageing drug.

More trees = more life in large city study

Washington Post - 09-Jul-2015

Study of city of 530,000 trees in Toronto compared to 30,000 residents health records.

Women haven’t always lived longer than men

Independent - 07-Jul-2015

Once infectious diseases conquered, deaths from cancer and cardiovascular disease (which affect men more than women) amplify life expectancy difference in 50 to 70 year olds.

Artificial blood human trials by 2017

Independent - 25-Jun-2015

NHS to test laboratory made blood – guaranteed infection free. Initial safety trials could lead to mass production of red blood cells for emergency transfusions.

Tissue scaffold technology could help rebuild large organs

Kurzweil Network - 19-Jun-2015

Large pieces of cartilage created. Aim is to repair damaged human joint tissue.

Skeletal muscle mass key factor in determining life expectancy

Taipei Times - 17-Jun-2015

Underweight elderly people have double the mortality rate of others.

Building and transplanting a bioengineered forelimb

Kurzweil Network - 05-Jun-2015

Functioning rat forelimb grown using decellularization / recellularization (decel/recel) technique.

The rich get older

Cosmos - 01-Jun-2015

Gains in US life expectancy mostly benefiting those with higher income.

Study Examines Epigenetic Regulation

Science World Report - 26-May-2015

Addition of glycine for 10 days to 97 year old fibroblast cell line helped to restore respiratory function.

Anti-aging drug may be just 5 years away

Times of India - 21-May-2015

Scientists at the University of Birmingham who have identified the role of the enzyme 11beta-HSD1 in the degenerative effects of aging.

Young Blood Heals Fractures in Older Bones

Discover - 20-May-2015

In mice – but no reason to assume the same isn’t true in humans. Fractured bones healed faster and more effectively in old mice paired with younger mice.

European Focus project aims to increase life expectancy in the EU by two years

Medical Xpress - 13-May-2015

Goal is to create mechanisms to be ahead of vulnerability to illness, or even of death.

Pill of super-protective ‘heavy’ fat may be key to eternal youth

New Scientist - 13-May-2015

Hydrogen replaced with deuterium strengthens bonds between molecules in cell membranes – could reduce free radical damage. Initial trials to try to slow the progression of Friedreich’s ataxia.

Skin Rejuvenation with Non-Invasive Pulsed Electric Fields (PEF)

Nature - 12-May-2015

PEF treatment resulted in formation of microvasculature, secretion of new collagen and increased metabolic activity in treated skin. New epidermis proliferation can improve skin barrier function against infection and hazardous materials.

Telomere Length and Mortality

Humanity+ - 04-May-2015

Danish study of 65,000 people shows telomere length robustly predicts longevity.

The Immortal Jellyfish

American Museum of Natural History - 04-May-2015

Turritopsis dohrnii grows to adulthood in a matter of weeks but can transform back into a polyp using transdifferentiation.

Biologists discover the key mechanism that triggers human ageing

ScienceAlert - 01-May-2015

Accumulated alterations in the structure of heterochromatin may be a major underlying cause of cellular aging.

Men ‘catching up’ on life expectancy

BBC - 30-Apr-2015

Closing the gap on women. By 2030 men will be living 85.7 years on average compare to 79.5 in 2012.

Functioning synthetic blood vessels become the real thing

GizMag - 29-Apr-2015

“vascular prostheses” were completely replaced by biological blood vessels within six months of being implanted. Additionally, no aneurysms, thromboses or inflammation were noted. The technology is still under development, with human trials expected to be

Why do Israelis live longer despite stress?

YNetNews - 26-Apr-2015

Geriatrics professor Devora Lieberman puts it down to awareness of preventive medicine and proper nutrition – eating food rich in fibers and low on sodium and fat.

Dmitry Kaminskiy offers $1m to first person to live to 123

Forbes - 21-Apr-2015

Could a financial incentive help people push the boundaries of lifespan?

First human head transplant planned

Independent - 08-Apr-2015

Russian man to become first to undergo pioneering and controversial surgery.

Energy for muscles and brains controlled by a single protein

Salk Institute - 07-Apr-2015

Salk scientists discover a single protein that energizes both muscles and the brain.

BioViva Moving Ahead With Human Gene Therapy for Telomerase Activation

Fight Aging! - 02-Apr-2015

First company to treat a person with gene therapy to reverse biological aging.

This face scan can help predict your biological age

Guardian - 31-Mar-2015

Simply captures a photo to reveal biological age - no blood tests needed

Broad Institute and Calico collaboration to find therapeutic approaches to diseases of aging

Calico - 17-Mar-2015

Calico is a Google-founded R&D company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan

Senolytics, A New Class Of Drugs, Slows Aging Process

Medical Daily - 11-Mar-2015

Senolytics, a new class of drugs, might dramatically slow the aging process and so change the face of old age.

Silicon Valley Is Trying to Make Humans Immortal—and Finding Some Success

Newsweek - 05-Mar-2015

Rejuvenating Old Brains with Young Blood

World Economic Forum - 24-Feb-2015

Tony Wyss-Coray from Stanford University presents the results of tests in mice with video footage of old mice performing better in a standard maze test after receiving blood from younger mice. Benefits possibly come mainly from plasma.

Higher death rate ‘driven by flu’

BBC - 04-Feb-2015

Two New Teams Join Global Effort to Bioengineer a New Liver

New Organ - 04-Feb-2015

New Organ, a collective initiative for biomedical engineering and regenerative medicine, announced today that two new teams have joined the field competing for the New Organ Liver Prize, a global competition sponsored by the Methuselah Foundation, a biome

Lack of senescence in hydra

Newser - 02-Feb-2015

A water-loving animal called the hydra seems to live forever.

Men born in 1913 followed to age 100 years

Scandinavian Cardiovascular Journal - 01-Feb-2015

To examine causes of death for men above 80 years of age, and health status in centenarians in a cohort of men followed from age 50 years. Factors of importance for survival were studied.

Telomere extension turns back aging clock in cultured human cells

Stanford University - 22-Jan-2015

Researchers delivered a modified RNA that encodes a telomere-extending protein to cultured human cells. Cell proliferation capacity was dramatically increased, yielding large numbers of cells for study.

Review of Mechanisms that Slow Aging from Calorie Restriction

Fight Aging! - 06-Jan-2015

CR changes near everything in the operation of metabolism and slows near every measure of aging making it difficult to figure out chains of cause and effect.

Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import –

PLOS Genetics - 18-Dec-2014

Geneu launches DNA matched anti-ageing serum

Telegraph - 30-Nov-2014

Everyday drugs could give extra years of life

New Scientist - 01-Oct-2014

Rapamycin in mice

UK centenarian numbers on the rise

BBC - 25-Sep-2014

The number of centenarians in the UK has more than quadrupled in the past 30 years, according to new figures.

It may be possible to slow or even reverse the effects of ageing by stimulating mitochondrial activity through exercise, diet or drugs.

New Scientist - 22-Sep-2014

Telomerase “off” switch discovered; stops cells dividing indefinitely

Salk Institute - 19-Sep-2014

The study was published in the Genes and Development journal.

AMPK gene can slow the aging process throughout the entire body

UCLA - 09-Sep-2014

A gene that can slow the aging process throughout the entire body when activated remotely was identified by UCLA scientists.

Scientists created the first functional thymus from lab-grown cells in mice

Centre for Regenerative Medicine (CRM) - 24-Aug-2014

Cellular reprogramming for readily available artificial transplantable organs

Survival benefits of metformin in non-diabetics: faulty analysis in a 2014 study

Science Media Centre - 08-Aug-2014

It's not logical to advise people without diabetes to take metformin

Tim Gibson talks to the FT about driving a cryonics ambulance

Financial Times - 27-Jun-2014

He loved the idea so much he bought the company!

Fate of Ming: the 507 years old clam

National Geographic - 17-Nov-2013

But there may be more older clams still living on the ocean floor

Rhodiola rosea found to increase fruit fly lifespan by 24% on top of restricted calorie effect.

Kurzweil Network - 20-Jun-2013

The herbal extract of a yellow-flowered mountain plant long used for stress relief was found to increase the lifespan of fruit fly populations by an average of 24 percent.

A simple, non-invasive gene therapy restores sight

Kurzweil Network - 14-Jun-2013

Researchers have developed an new method for inserting genes into retina cells.

How to quickly generate a large quantity of personalized nerve cells

Kurzweil Network - 14-Jun-2013

Embryonic stem cells (or ESCs) and induced pluripotent stem cells (iPSCs) are prized because they can replicate themselves indefinitely in a dish or differentiate into every cell type in the body.

Turning human spare parts into exports

Kurzweil Network - 13-Jun-2013

Lifespan-extending drug given late in life reverses age-related heart disease in mice

Kurzweil Network - 12-Jun-2013

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.

Organ, tissue replacement could end aging by mid-2020s

Institute for Ethics and Emerging Technologies (IEET) - 14-May-2013

Gene therapy: ‘Heart-healing virus’ trial starts

BBC - 30-Apr-2013

Young blood therapy - the real deal to longevity?

h+ Magazine - 02-Apr-2013

Transfusing youthful blood factors into an older patient could be a reality soon

Molecular clock reversed in mice using SIRT3 infusion

Fight Aging! - 31-Jan-2013

Could SIRT3 promotion in humans help with age-related oxidative stress?

Yamanaka's simple yet brilliant method to produce induced pluripotent stem cells

UCSF - 09-Oct-2012

His discovery fast tracked the field of regenerative medicine by many miles

One face, two ages: how the sun can age you prematurely

The Guardian - 05-Jun-2012

A truck driver's face shows devastating effects of 28 years of sun exposure

Human mortality beyond age 110

Max Planck Institute for Demographic Research (MPIDR) - 01-Jan-2010

After age 110 mortality rates level off corresponding to an annual probability of death of 50%

‘Proof’ Boots Protect & Perfect Intense Beauty Serum beats wrinkles

BBC - 28-Apr-2009

Scientists say they have clinical proof that a face cream available on the high street does reduce wrinkles.