Key points from article :
Successful folding, aggregation and chaperoning of proteins keep young cells healthy.
With cumulative oxidative damage, protein misfolding becomes rampant and cell death occurs.
Tested this theory using a model of the worm (C. elegans).
This mathematical model describes a range of cellular processes across the cell's whole proteome.
Needs to study molecular origins of age-related diseases based on protein misfolding processes.
Study by Stony Brook University, published in Proceedings of the National Academy of Sciences.
