Join the club for FREE to access the whole archive and other member benefits.

AI-designed proteins create blood vessels from stem cells

This opens up new possibilities for regenerative medicine and tissue repair

17-Jun-2024

Key points from article :

Researchers at the University of Washington used AI to design circular protein molecules to control fibroblast growth factor receptor (FGFR) signaling, which is crucial for blood vessel development.

These AI-generated molecules, called oligomers, successfully nudged human stem cells into different blood vessel cell types.

The oligomers also facilitated the creation of 3D blood vessel organoids in a dish, which integrated with existing blood vessels when transplanted into mice.

This research offers a promising new approach for regenerative medicine, as it could potentially help repair damaged tissues by promoting new blood vessel growth.

While this study focused on blood vessels, the AI-based technique could be applied to other tissues, potentially leading to new treatments for various conditions.

Mentioned in this article:

Click on resource name for more details.

University of Washington (UW)

Public research university in Seattle, Washington

Topics mentioned on this page:
Stem Cells, AI in Medical Research
AI-designed proteins create blood vessels from stem cells