Key points from article :
Fisetin reduces level of senescent cells in the body.
Found in many fruit and veg, e.g. strawberries, apples, onions & cucumbers.
Old mice treated with this compound saw improvement in health and lifespan.
Still many questions to address, including the right dosage.
Used mass cytometry (CyTOF) to show effects on specific subsets of damaged cells.
Paper describing senotherapeutic was recently published in EBioMedicine.
The study on possibility to reduce the burden of damaged cells was published in Nature Medicine.
