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Cellular aging halted by hydrogen sulfide gas

3 compounds designed to deliver minute amounts of hydrogen to mitochondria inhibit cellular aging

07-Aug-2018

Key points from article :

University of Exeter targeted splicing factors within the mitochondria.

Used samples of endothelial cells that line the inside of blood vessels.

Team designed novel chemicals that targeted either SRSF2 or HNRNPD.

Compounds delivered a minute dose of hydrogen sulfide gas to mitochondria.

Gas fires up the splicing factors, giving mitochondria a boost.

Senescent cells in the sample dropped by an impressive 50 percent.

The study was published in journal Aging.

Mentioned in this article:

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Aging

Bio-medical journal covering research on all aspects of gerontology

Lorna Harries

Professor of Molecular Genetics at the University of Exeter

University of Exeter

UK university and member of the Russell Group of leading research-intensive UK universities

Topics mentioned on this page:
Senescent Cells, Mitochondria