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Cellular aging halted by hydrogen sulfide gas


Key points from article :

University of Exeter targeted splicing factors within the mitochondria.

Used samples of endothelial cells that line the inside of blood vessels.

Team designed novel chemicals that targeted either SRSF2 or HNRNPD.

Compounds delivered a minute dose of hydrogen sulfide gas to mitochondria.

Gas fires up the splicing factors, giving mitochondria a boost.

Senescent cells in the sample dropped by an impressive 50 percent.

The study was published in journal Aging.

3 compounds designed to deliver minute amounts of hydrogen to mitochondria inhibit cellular aging

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Bio-medical journal covering research on all aspects of gerontology


Professor of Molecular Genetics at the University of Exeter.


UK university and member of the Russell Group of leading research-intensive UK universities