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Novel approaches to CNS diseases done by Cerevance

After a successful phase 1 trial of the CVN424 done one mice, the company started phase 2 studies

03-Mar-2020

Key points from article :

NETSseq technology profiles specific brain cell types using post mortem human brain tissue samples from donors.

Cerevance collected over 7,000 human brain tissue samples from donors ranging in age from 8 to 97.

Scientists use antibodies against nuclear proteins, endoplasmic reticulum proteins, and membrane proteins.

With NETSseq technology scientists can also compare healthy and diseased cells, subpopulations.

Company is now working on a specific compound for the treatment of Parkinson’s disease called CVN424.

Company is raising $60m for the CVN424 program and for starting at least 4 new programs.

Mentioned in this article:

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Brad Margus

Co-founder & CEO at Cerevance

Cerevance

Targeting cell-type-specific proteins to develop new treatments for brain disease

Nathaniel Heintz

Professor of Molecular Biology at The Rockefeller University

Topics mentioned on this page:
Parkinson’s Disease, Investments