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Nucleolus is a life expectancy predictor

31-Aug-2017

Key points from article :

The nucleolus is a major structure in a cell's nucleus responsilbe for ribosome biogenesis.

Max Planck Institute for Biology of Ageing has discovered a link between its size and life expectancy.

Biomarker found in study of long-lived roundworm Caenorhabditis elegans mutants.

Mutants showed smaller nucleoli than their shorter-lived relatives.

Size link was independent of the pathway that led to their longevity.

Molecules within the nucleolus could causally impact life expectancy.

Effect also seen in human muscle biopsies.

The study was published in the Nature Communications journal.

Mentioned in this article:

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Adam Antebi

Professor in Department of Molecular Genetics of Ageing at Max Planck Institute for Biology of Ageing

Max Planck Institute for Biology of Ageing

Scientific research institute dedicated to age research

Nature Communications

Journal covering all topics in physics, chemistry, and biology

Varnesh Tiku

Postdoctoral Scientist at Genentech.

Topics mentioned on this page:
Biological Age