Key points from article :
Peter de Keizer of the Erasmus University Medical Center discusses strategy of removing senescent cells.
Need to identify how senescence impairs tissue rejuvenation and design compounds that can both target senescence and stimulate rejuvenation in a safe manner.
Cell-penetrating peptides may provide promising therapeutics.
With anti-senescence therapies we are the furthest we have ever been on the path to healthspan extension and restoration of the loss of health experienced during aging.
The study was published in the Trends in Molecular Medicine journal.