Key points from article :
It is likely that senescent cells play a significant role in the development and progression of asthma.
Limited data has shown that cellular senescence is accelerated in asthma.
Considers azithromycin which belongs to the antibiotic group macrolide as a potential candidate.
Azithromycin removed 97% of senescent human lung fibroblasts in an in-vitro study.
Potential to reduce the senescence-associated secretory phenotype (SASP) in asthmatic lungs.
Potential to develop a repair-based therapy to treat asthma in the future.
Research by San Yat-sen University, published in Frontiers in Cell and Developmental Biology.
