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Scientists revive frozen human brain tissue without any damage

Novel technique raises hope for studying brain complexities


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Scientists developed a technique to freeze and revive human brain tissue without damage.

This could potentially improve ways of studying neurological diseases.

Human embryonic stem cells are used to grow self-organizing brain samples, known as organoids, for three weeks.

They froze the organoids in a special chemical solution named MEDY.

After thawing, the frozen organoids functioned similarly to unfrozen ones.

MEDY preserved tissue from a 9-month-old girl's brain for at least two weeks.

With significantly more research and the use of larger tissues, the work could one day lead to freezing entire brains, says João Pedro Magalhães.

Study by Fudan University, published in the journal Cell Reports

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Cell Reports

Journal publishing research papers across a broad range of disciplines within the life sciences

Fudan University

Globally ranked, research-oriented university, Shanghai, China

João Pedro de Magalhães

Professor of Molecular Biogerontology at University of Birmingham Institute of Inflammation and Ageing, consultant, futurist, speaker

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Scientists revive frozen human brain tissue without any damage