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SASP Atlas created by team of researchers

28-Jan-2020

Key points from article :

New atlas represents the culmination of many years of research for full database.

Accumulation of senescent cells and resulting SASP is one of the hallmarks of aging.

Each profile consists of hundreds of largely distinct proteins.

Also includes a subset of proteins elevated in all SASPs.

Aims to help researchers to develop more clinically relevant biomarkers for detecting SASPs.

Big help as SASP is a promising therapeutic target for multiple age-related conditions.

Research by Buck Institute for Research on Aging, University of Washington, Intramural Research Program of the National Institute on Aging, and Lawence Berkeley Laboratory.

Published in PLOS Biology.

It is a comprehensive proteomic database of soluble proteins and exosomal cargo SASP factors

Mentioned in this article:

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Institute

Independent biomedical research institute focused on aging

Academic

Professor of biogerontology and Biochemist.

Journal

Journal providing information from all aspects of biology.

Information

Proteomic Atlas of SAS