Key points from article :
Technology Networks interviewed Chris Overall, Chair at Chromosome-Centric Human Proteome Project.
90% of the human proteome has been mapped by HPP.
10% missing protein gap is due to rarely or minutely expressed proteins.
Genomics cannot provide all the answers or diagnostics for diseases lacking a genetic basis.
Deciphering proteoforms as biomarkers provides accurate & timely information of the disease.
This can be translated to tests suitable for deployment in hospitals, diagnostic labs and even bed side.
Our genomes provide instructions on how our proteins are weaved together to define our individuality.
Our individuality in turn, defines how prone we may be to different diseases, ageing and other stressors.
It is to understand this pattern, and how it changes, that proteomics is so vital.
