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Dresden merges recombinases & DNA-binding domains for tailored gene editing

The research offers safer and more precise ways to treat genetic disorders

31-Jan-2024

Key points from article :

Dresden researchers combine special proteins called "recombinases" with DNA-targeting tools for pinpoint accuracy.

Think of it like a custom DNA editing tool. This method allows scientists to choose exactly where in the genome they want to make changes, unlike older methods.

This new technique sidesteps the unpredictable repair mechanisms usually used in gene editing, making it safer and more reliable.

This discovery opens doors for developing treatments for genetic conditions and exploring other biomedical applications.

Seamless Therapeutics, founded by the research team, is working to turn this potential into real-world therapies.

This research could pave the way for safer, more effective treatments for a wide range of diseases.

Recent findings published in Nature Biotechnology.

Mentioned in this article:

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Nature Biotechnology

Journal providing information from all areas of biotechnology

Seamless Therapeutics

Gene editing company focused on recombinases

TU Dresden (University of Technology)

Engineering sciences university in Germany

Topics mentioned on this page:
Gene Therapy
Dresden merges recombinases & DNA-binding domains for tailored gene editing