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NICE - faecal transplants can be offered for hard-to-treat C. difficile

A solution to reduce both antibiotic usage and antimicrobial resistance

31-Aug-2022

Key points from article :

National Institute for Health and Care Excellence said people with recurrent illness caused by hard-to-treat bacterium Clostridium difficile can be offered faecal transplants.

C. diff can cause infection if the balance of bowel bacteria changes - for example, after taking antibiotics.

The transplants transfer beneficial gut bacteria from a healthy donor's faeces.

Clinical trials show they are more effective than antibiotics, to which this "superbug" can become resistant.

Common symptoms of a C. diff infection: diarrhoea, high temperature, appetite loss, nausea, stomachache.

NICE estimates 450-500 people each year in England could receive the transplants, saving thousands of pounds.

NICE medical technology director Mark Chapman said: "Use of this treatment will also help reduce the reliance on antibiotics and in turn reduce the chances of antimicrobial resistance, which supports NICE's guidance on good antimicrobial stewardship."




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Mark Chapman

Interim director of medical technology and digital evaluation at NICE

National Institute for Health and Care Excellence (NICE)

This institution provides national guidance and advice to improve health and social care.

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Microbiome
NICE - faecal transplants can be offered for hard-to-treat C. difficile