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Gene therapy triggers natural blood vessel growth in angina patients

Treatment shows improved blood flow, exercise tolerance and reduced symptoms

02-May-2024

Key points from article :

Gene therapy (XC001) for severe angina (no other options) shows promise in a year-long study.

The therapy is designed to trigger the body's natural process of growing new blood vessels.

Among 32 patients with severe angina, the gene therapy appeared safe with no serious side effects.

Patients experienced benefits including increased exercise duration, reduced angina symptoms, and improved blood flow.

“Findings may not impact clinical practice immediately, but it will lay the groundwork for future studies in this patient population,” said Thomas Povsic, Co-lead authors of the study.

Researchers believe this could lead to new treatments for coronary artery disease or angina.

This therapy might be useful for patients who can't undergo conventional therapies like PCI or CABG.

Study by Duke University and University of Washington, presented at SCAI.

Mentioned in this article:

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Duke University

Private research university in Durham, North Carolina

Thomas Povsic

Professor of Medicine/Cardiology at Duke University

University of Washington (UW)

Public research university in Seattle, Washington

Topics mentioned on this page:
Gene Therapy, Heart Disease
Gene therapy triggers natural blood vessel growth in angina patients