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J&J extends $30m deal with Nanobiotix for global co-development of radioenhancer

NBTXR3 to enhance the effect of immunotherapies; plans for phase 3 trial in head and neck cancer

10-Jul-2023

Key points from article :

Johnson & Johnson is paying $30 million upfront in cash for the global rights of a phase 3 cancer prospect at Nanobiotix.

The candidate, NBTXR3, enhances the efficacy of radiotherapy to improve outcomes in tumor types.

Metabolically inert nano- particles in NBTXR3 interact with X-rays, driving more electrons to increase the death of cancer cells.

Plans to run a phase 3 trial in recurrent and metastatic head and neck cancer in combination with an anti-PD-1 drug.

The Big Pharma may provide “in-kind regulatory and development support” worth a further $30 million “at its sole discretion.”

Deal also features a $5 million investment in Nanobiotix, with a second $25 million tranche potentially following in a future financing.

Bigger paydays await Nanobiotix if the phase 3 trial hits its endpoints and triggers a successful development and commercialization.

The deal is worth up to $1.8 billion in development, regulatory and sales milestones.

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Johnson & Johnson

Largest healthcare company that develops medical devices, pharmaceuticals, and consumer packaged goods

Nanobiotix

Biotechnology company uses nanoparticles and radiotherapy for cancer

Topics mentioned on this page:
Investments, Cancer
J&J extends $30m deal with Nanobiotix for global co-development of radioenhancer