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What's unique in the brain functional connectivity of centenarians?


Key points from article :

People aged 95 and over demonstrated stronger brain activation than their younger counterparts.

Research investigated brain functional characteristics in the extreme age range.

Compared 57 individuals aged 95-103 years with 66 cognitively unimpaired participants aged 76-79.

Findings show coupled activation of bilateral fronto-parietal control networks.

Which contributed to better performance on visuospatial cognitive tasks.

Emphasized importance in adaptability of cognition to ageing, disease, a.k.a. cognitive reserve.

Future studies can then investigate the underlying mechanisms for this cognitive reserve.

And develop potential therapeutic strategies against age-related decline.

Research by UNSW's Centre for Healthy Brain Ageing (CHeBA), published in NeuroImage.

World-first research reveals how their brain adapts to ageing changes, still perform well

Mentioned in this article:

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Centre for Healthy Brain Ageing (CHeBA)

Premier research institution at UNSW Sydney

Jiyang Jiang

Neuroimaging expert, UNSW's Centre for Healthy Brain Ageing (CHeBA)


Peer-reviewed scientific journal covering research on neuroimaging

Perminder Sachdev

Neuropsychiatrist, Professor, UNSW

Sydney Centenarian Study

Longitudinal project on centenarians, CHeBA, UNSW

University of New South Wales (UNSW)

Public Research university.