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First iPS Cell Trial for Heart Disease Soon

Researchers plan to implant induced stem cell-sheets on the heart to regenerate injured areas

31-Aug-2018

Key points from article :

Clinical trial in Japan will use reprogrammed stem cells to regenerate injured hearts.

Sheets of stem cell derived cardiomyocytes will be implanted into three patients.

Participants will receive iPS-derived cells from a donor, instead of their own tissue.

Induced pluripotent stem cells have proven effective in improving heart function in animal models.

Unclear whether cells become beating heart cells or just release factors that help existing cells.

Team led by Osaka University cardiac surgeon Yoshiki Sawa.

The study was published in the Nature journal.

Mentioned in this article:

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Nature

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

Osaka University

Public Research university.

Phillip Yang

Associate Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center.

Yoshiki Sawa

Cardiac surgeon and Professor at Osaka University.

Topics mentioned on this page:
Stem Cells