Key points from article :
Ageing individuals are often classified as robust, frail or dependent depending on their physical conditions.
Frailty is identified by weight loss, fatigue, and impairments.
The study led by Aurélie Mailliez, and overseen by Dr Éric Boulanger, identified blood biomarkers associated with physical frailty.
“One solution is to develop biomarkers of aging.” says Dr Eric Verdin.
To identify reliable biomarkers of frailty, the team analysed 67 studies, having 32,934 subjects and 6864 frail individuals. This analysis identified C-reactive protein (CRP), albumin, haemoglobin, 25-hydroxyvitamin D and free testosterone (in men) as biomarkers.
Mounting evidence suggests their potential value as simple, non-invasive, economical and robust biomarkers of frailty.
Findings by CHU Lille were recently published in the journal Experimental Gerontology.
