Key points from article :
Open Longevity Foundation released a novel database of genes involved in human aging and longevity — Open Genes.
It includes information on more than 2,400 genes, the most extensive mapping of human genetics of aging to date.
Open Genes provides a comprehensive analysis of all human genes involved in major aging processes, contribution into life expectancy and genetic interventions, which affect lifespan of model animals.
It describes
- 2,402 age-related genes, from 1,700 unique research articles
- more than 2,000 genetic interventions, affecting lifespan of model animals
- 4,648 records of age-related changes in gene activity
- 1,458 records on longevity associations with gene variants
The Open Genes team has already identified 25 genes that extended life in mammals.
