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Open genes-comprehensive database of genes associated with aging and longevity

Open gene database simplifies the search for potential aging therapy targets

24-Jan-2023

Key points from article :

Open Longevity Foundation released a novel database of genes involved in human aging and longevity — Open Genes.

It includes information on more than 2,400 genes, the most extensive mapping of human genetics of aging to date.

Open Genes provides a comprehensive analysis of all human genes involved in major aging processes, contribution into life expectancy and genetic interventions, which affect lifespan of model animals.

It describes

  1. 2,402 age-related genes, from 1,700 unique research articles
  2. more than 2,000 genetic interventions, affecting lifespan of model animals
  3. 4,648 records of age-related changes in gene activity
  4. 1,458 records on longevity associations with gene variants

The Open Genes team has already identified 25 genes that extended life in mammals.

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Open Longevity

Non-profit community planning to stop and reverse human biological aging with open research projects

Topics mentioned on this page:
Longevity Genes, Ageing Research
Open genes-comprehensive database of genes associated with aging and longevity