Key points from article :
CRMP makes the liver to waste energy, so the liver starts to use more than normal.
CRMP lets protons flow out of mitochondria without generating ATP.
Unlike dinitrophenol, CRMP affects mainly liver cells rather than the entire body.
Shulman wants to carry out further animal tests of CRMP before moving on to human trials.
Some subsequent trials might test CRMP in combination with existing drugs for type 2 diabetes.