Key points from article :
Nicola Bagalà interviews Dr. Judith Campisi - professor at the Buck Institute for Research on Aging.
New tools to explore cells have really made progress in aging research possible.
The first senolytic drugs have just entered clinical trials for humans.
Senolytics could address neurodegeneration, cancer, kidneys, joints, and heart disease.
Senescent cells usually use the same mechanisms as cancer to avoid cell death.
To cure cancer, you have to kill every cancer cell, a single cell can go on and form a tumour.
Killing between 60 and 80% of the senescent cells in mice sees an improvement in healthspan.
Some compounds might suppress the SASP, rather than remove senescent cells.
But this would require continuous use of compound, e.g. plant flavonoids.
