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Possible way to stop activation of proteins known to cause age-related diseases

15-Dec-2016

Key points from article :

Scientists have discovered that it is possible to stop the activation of a group of proteins – NADPH Oxidase.

NADPH Oxidase complex attacks blood vessels, the heart lining, joints and the brain when placed under metabolic stress, causing most of the diseases of ageing.

But also needed for cell communication.

Researchers have found a single nucleotide polymorphism (SNP) that protects against cardiovascular disease and also affects the activation of NADPH oxidase.

Drugs could be designed to prevent the activation process in conditions of stress, without affecting cell health.

Mentioned in this article:

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Brendan Howlin

Senior Lecturer in Computational Chemistry at the University of Surrey.

Royal Berkshire NHS Foundation Trust

National Health Service hospital in the town of Reading.

University of Cologne

University in Cologne, Germany.

University of Reading

Public university in Reading, England

University of Surrey

Public research university for UK and international students

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Gene Therapy