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Senescent cell inflammatory signals as a new possible biomarker

It could measure biological age and relative health

29-Jun-2020

Key points from article :

Senescence-associated secretory phenotype (SASP) as a biomarker to measure ageing, health.

Researchers identified 7 factors they believe give a reliable indication of these.

A community-based sample of people aged 20–90 years (retrospective cross-sectional) was studied.

This is to test to test associations between circulating SASP factors and chronological age.

SASP proteins were positively associated with age, frailty, and adverse postsurgery outcomes.

Could be useful in quantifying the presence and level of senescent cells.

As well as their subsequent health risks in older people.

Researchers from Robert and Arlene Kogod Center on Aging and other respectable institutions.

Published in JCI Insight.

Mentioned in this article:

Click on resource name for more details.

Mayo Clinic

Non-profit American academic medical center focused on health care, education, and research

The Journal of Clinical Investigation (JCI)

Monthly peer-reviewed medical journal covering biomedical research

Topics mentioned on this page:
Biological Age, Senescent Cells