Key points from article :
Chimeric antigen receptor (CAR) T cells are genetically engineered immune T cells.
Hunts down cancer cells and kill them with precision.
Designed CAR T cells that recognize urokinase plasminogen activator receptor (uPAR).
uPAR is abundant on senescent cells but mostly absent on normal cells.
Successfully eliminated senescent cells from two different mouse models of liver fibrosis.
Improved survival in mouse models of lung cancer.
Plans to determine if this works against atherosclerosis, diabetes and osteoarthritis.
Research by Memorial Sloan Kettering published in the journal Nature.
