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Regenerative hearing drug shows promise in early clinical trials

Drug LY3056480 didn't fix hearing completely but 45% participants showed better results

05-Mar-2024

Key points from article :

University College London and University College London Hospitals NHS Foundation Trust researchers scientists conducted the first-ever trial of a regenerative drug (LY3056480) to restore hearing loss.

The trial involved injecting the drug into the ears of adults with mild to moderate hearing loss.

While overall hearing wasn't restored, 45% of participants showed improvement in specific tests, suggesting the drug might partially work.

Researchers need to refine the drug and patient selection based on learnings from this initial trial.

This trial is a significant step as traditionally, hearing loss is irreversible and only managed with hearing aids.

The research team is optimistic about future advancements in regenerative therapies for hearing loss.

The results of the study were published in Nature Communications

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Nature Communications

Journal covering all topics in physics, chemistry, and biology

University College London (UCL)

Diverse global community of world-class academics, students, industry links, external partners, and alumni

University College London Hospitals NHS Foundation Trust

NHS foundation trust based in London, UK

Topics mentioned on this page:
Hearing Loss, Regenerative Medicine
Regenerative hearing drug shows promise in early clinical trials