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Fisetin's potential to become the first line senolytic pill

Mice fed with fisetin diets lived much longer


Key points from article :

Fisetin is a flavonoid that is very close in structure to quercetin.

It’s the latest candidate for a senolytic pill.

It's a plant based chemical that can kill off senescent cells without harming normal cells.

Fisetin is cheap, easily available and widely-regarded as safe, but it lacks adequate studies.

Has anti-cancer activity and inhibit inflammatory signals.

In vivo tests in mice model resulted in an impressive increase in life span.

Efficacy, safety and dosing regimens are yet to be studied for Fisetin.

The study was published in EBioMedicine journal.

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Mayo Clinic

Non-profit American academic medical center focused on health care, education, and research

Topics mentioned on this page:
Senescent Cells