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Reversible reprogramming regenerates cardiac tissue after a heart attack

23-Sep-2021

Key points from article :

Researchers showed, they could reprogram heart cells in mice to regenerate cardiac tissue after a heart attack.

Helps patients recover muscle lost in heart attacks and gives another boon to anti-aging researchers.

Cardiovascular issue is a leading causes of mortality in aging. Reprogramming the heart would be impactful.

Adults today have cholesterol-lowering treatments that can help stave off heart attacks.

Patients who suffer such attacks can take beta-blockers and one of a couple new drugs to slow their decline.

But their decline is effectively inevitable, heart cells are some of the most inflexible in the body.

Liver or muscle, don’t regenerate when injured, that paints a grim prognosis for people with heart failure.

Researchers treated mice with the antibiotic to express the factors before inducing in them a massive heart attack.

James Martin says "It opens the door to further development of treatment".

Research by Max Planck Institute for Heart and Lung Research published in Science

Possibility of regeneration: A boon to the broad rejuvenation field

Mentioned in this article:

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Academic

Professor at Baylor College of Medicine

Journal

Peer-reviewed academic online journal of the American Association for the Advancement of Science (AAAS)

Academia

Professor in Department of Cardiac Development and Remodelling at Max Planck Institute for Heart and Lung Research