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Daily supplementation with urolithin A helps treat muscle fatigue

Boosts mitrochondrial health & muscle activity in aged people and those who don't exercise enough

25-Jan-2022

Key points from article :

As people get older, they tend to lose muscle mass, strength, and endurance.

Gut bacteria produce urolithin A by breaking down polyphenols in pomegranates, nuts, and berries.

This compound improves the overall efficiency of mitochondria and improves muscle function.

Gut bacteria of some people may not generate sufficient quantities due to aging, poor diet, and disease.

Preliminary clinical trial conducted to find out safety and effectiveness of the supplement.

66 older people (mean age, 72 years) were assigned 1,000mg of urolithin A daily for 4 months or a placebo.

Supplement improved muscle endurance, reduced inflammation, and healthier mitochondria.

Amazentis funded the study and manufactures the supplement.

“A promising approach to counteract age-associated muscle decline. Future study to confirm its role in healthy aging,” - David Marcinek, co-author.

“...benefit people who are unable to get enough exercise.”

Study by University of Washington School of Medicine published in JAMA Network Open.

Mentioned in this article:

Click on resource name for more details.

Amazentis

Company focused to clinical development of naturally derived bioactives.

David Marcinek

Professor in the Department of Radiology at University of Washington School of Medicine

JAMA Network Open

Medical journal dedicated to biomedical sciences.

Washington University School of Medicine

Medical school of Washington University in St. Louis

Topics mentioned on this page:
Supplements, Microbiome