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Telomerase Gene Therapy Does Not Increase Cancer Risk

New research proves telomerase therapy's safety by making its effects within the cell temporary

27-Aug-2018

Key points from article :

Gene therapy study reactivated telomerase gene in cells.

Used an adeno-associated virus (AAV) to deliver the payload.

Study used mouse model that is at high risk of lung cancer.

Did not increase the risk of developing cancer.

Does not integrate into the genomes of the target cells.

Telomerase activation only lasts for a few cell cycles.

Effective against cardiac infarct, aplastic anemia, & pulmonary fibrosis.

The study was published in the journal PLOS Genetics.

Mentioned in this article:

Click on resource name for more details.

Maria Blasco

Director of Spanish National Cancer Research Centre.

PLOS Genetics

Scientific journal that publishes human studies and original contributions in all areas of biology

Spanish National Cancer Research Center (CNIO)

Center for cancer research, including diagnosis and treatments.

Topics mentioned on this page:
Telomeres