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Recalibration of signalling factors to more youthful levels in the blood

03-Sep-2019

Key points from article :

Rejuvenation might be achieved by the calibration of age-related changes signals found in the blood.

Tissue ageing could be reversed in a matter of weeks with the beneficial signals from the younger animal.

Protein TGF-β1 was found to prevent stem cells from repairing tissue properly in old and young mice.

Scientists were able to reduce TGF-β1 levels and increase oxytocin.

Changing the molecule levels in the blood resulted in promoted rejuvenation and increased neurogenesis.

Recalibration of these signalling factors back reduced the p16 biomarker of cellular senescence.

The study was published in journal Aging.

Adjusting the levels of just two molecules in the blood could lead to significant rejuvenation

Mentioned in this article:

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Journal

Bio-medical journal covering research on all aspects of gerontology

Academic

Professor of Bioengineering at Berkeley University of California.

Academic

Lecturer in Department of Bioengineering at Berkley University of California.