Key points from article :
Scientists at MIT developed a device to make cell therapies (particularly for spinal cord injuries) safer.
In cell therapy, stem cells are converted into specialized cells for transplantation. However, leftover undifferentiated stem cells can form tumors.
The team created a microfluidic cell sorter that separates cells by size. Undifferentiated stem cells are usually larger, allowing their removal.
The device uses fluid flow through a spiral channel at high speeds. Forces within the channel sort cells based on size, requiring no filters or chemicals.
It removes roughly 50% of undifferentiated stem cells, greatly reducing tumor risk. Its low-cost plastic design makes it scalable for widespread use.
This innovation could make cell therapies safer and more effective, potentially leading to breakthroughs in treating spinal cord injuries.
The study was published in Stem Cells Translational Medicine.
