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Telomere loop structure more important than length


Key points from article :

People born with abnormally short telomeres suffer a variety of conditions.

New research identifies why telomeres change from healthy to unhealthy with age.

Telomeres normally form a loop structure, where the chromosome end is hidden.

When loop unfolds, the chromosome end is exposed and perceived as broken DNA.

It is not telomere length that matters, but telomere structure.

New super-resolution microscopy allows loops to be seen.

The study was published in the journal Molecular Cell.

Telomere structure rather than length may be the key to prevent aging

Mentioned in this article:

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Anthony (Tony) Cesare

Leader of the CMRI Genome Integrity Group and Associate Professor.

Children's Medical Research Institute (CMRI)

Organisation committed to the treatment or prevention of birth defects and childhood disease.

Katharina Gaus

Professor at University of New South Wales, immunologist and molecular microscopist.

Molecular Cell

Journal that covers research on cell biology at the molecular level.

University of New South Wales (UNSW)

Public Research university.