Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
University of Exeter spinout aiming to develop senotherapeutic interventions
Biotech company that specializes in the discovery and validation of microRNA biomarkers.
Fast generation of functional therapeutic antibodies.
Company that target cancer by developing senescence inducing and senolytic (senescent cell killing) compounds.
Company that develops and invests in drugs and technologies which prolong human lifespan.
Anti-aging company developing senoblockers.
Biopharmaceutical company focused on discovering and developing drugs against aging disorders and cancer.
Biotechnology company producing therapy that targets and destroys senescent cells.
Biotechnology company focused on development of treatments for age related diseases..
Cleara is developing therapeutics to eliminate senescent cells.
Low magnitude vibration to prevent/delay age-related bone loss in rats
Lifespan.io (LEAF) - 05-May-2021
Vibration treatment eliminates senescence of bone cells - may not be applicable to other tissuesRead more...
SenNet: a new NIH initiative to fight ageing
Lifespan.io (LEAF) - 06-Apr-2021
Establishing a massive database on cellular senescence to improve human healthRead more...
First ever non-invasive biomarker test to detect senolysis
Buck Institute - 02-Apr-2021
Detectible senescence-specific biomarker allows development of new drugs for age-related conditionsRead more...