Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
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Phase I trial shows early promise in clearing senescent cells in Alzheimer's
Wake Forest Baptist Health - 07-Sep-2023
The treatment was well-tolerated with no significant changes in brain functionRead more...
Senolytics have gender-specific effects on ageing in young mice
Lifespan.io (LEAF) - 30-Aug-2023
More research is needed to determine the safety and efficacy of senolytics in humansRead more...
AI identifies new senolytics that could treat age-related diseases
Lifespan.io (LEAF) - 09-Aug-2023
Three natural compounds identified, paving the way for new treatmentsRead more...
Experimental vaccine promises to slow down or prevent Alzheimer's in mice
American Heart Association - 30-Jul-2023
Vaccine not only reduced inflammation, but also improved behavior and awareness in miceRead more...
Tiny sea creature unlocks the secrets of healing and aging
Phys.org - 30-Jun-2023
Insights on the evolution of ageing and may help advance regenerative medicineRead more...