Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

Draft page - more coming soon.

Recent News

UNITY Biotechnologies Selects a New Senolytic Candidate

LEAF - 14-Jan-2019

Very early days but good to have more senolytics in the pipeline

Senolytics for IPF human clinical trial results released

LEAF - 07-Jan-2019

Physical improvements recorded, but pulmonary function was unchcanged

Fisetin destroys senescent cells, but safe dosage not determined yet

LEAF - 26-Dec-2018

Includes table of fisetin content in range of fruits and vegetables

More Senescent Cells News