Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
CellAge - working with the aim to develop synthetic promoters that would be able to specifically identify senescent cells
Biotein - Company in the field of longevity and biotechnology that aims to provide a novel way to eradicate senescent cells.
UNITY Biotechnology - Biotechnology company devoted to research of restoring human health.More Senescent Cells resources
Senescent cell inflammatory signals as a new possible biomarker
Life Extension Advocacy Foundation (LEAF) - 29-Jun-2020
It could measure biological age and relative healthRead more...
Immunotherapy as new approach to battle senescent cells
Life Extension Advocacy Foundation (LEAF) - 23-Jun-2020
Successful in mice, it may help treat many age-related disease in humanRead more...
Harmful effects of senolytic drug Navitoclax in aged mice
Fight Aging! - 19-Jun-2020
Short-term treatment of this drug demonstrated cytotoxicity among other risksRead more...