Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
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Novel experiment explores a new way of reducing senescent cell burden
Live Forever Club - 12-Nov-2022
BDNF-TrkB pathway shows a lot of promise in lowering senescent cells in older organsRead more...
Senolytics-a risky proposition in aging and repair mechanisms
Lifespan.io (LEAF) - 19-Oct-2022
The study is a caution for scientists engaging in self-experimentation with senolyticsRead more...
$2.5M seed financing round closed by Cleara Biotech-targets cellular senescence
Longevity Technology - 03-Oct-2022
Cleara’s novel FOXO4-based treatment approach-ability to eliminate biomarker-positive scarred cellsRead more...
Regenerative therapies and senolytics help to rejuvenate the heart’s capacity to regenerate
Longevity Technology - 17-Aug-2022
Eliminating senescent cells rejuvenates the heart's capacity for regeneration in miceRead more...
Data from Phase 2 BEHOLD study of UBX1325 in DME patients-Unity Biotechnology
Ophthalmology Times - 12-Aug-2022
Statistically significant treatment effect for both BCVA and CST was seen at both 12 and 18 weeksRead more...