Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

Draft page - more coming soon.

Recent News

Synthetic antibodies able to target senescent cells

University of Leicester - 06-Mar-2019

nanoMIPs could improve the specificity of senolytics

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UNITY Biotechnology expands trial of osteoarthritis senolytic

UNITY Biotechnology - 22-Jan-2019

Initial results must be promising to enrol more patients at highest dosage

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UNITY Biotechnologies Selects a New Senolytic Candidate

Life Extension Advocacy Foundation (LEAF) - 14-Jan-2019

Very early days but good to have more senolytics in the pipeline

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More Senescent Cells News