Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
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Biotechnology company devoted to research of restoring human health
University of Exeter spinout aiming to develop senotherapeutic interventions
Biotech company that specializes in the discovery and validation of microRNA biomarkers.
Fast generation of functional therapeutic antibodies.
Company that target cancer by developing senescence inducing and senolytic (senescent cell killing) compounds.
Company that develops and invests in drugs and technologies which prolong human lifespan.
Anti-aging company developing senoblockers.
Biopharmaceutical company focused on discovering and developing drugs against aging disorders and cancer.
Biotechnology company producing therapy that targets and destroys senescent cells.
Biotechnology company focused on development of treatments for age related diseases..
Senolytic drugs improved survival rates in coronavirus-infected mice
SENS Research Foundation - 07-Oct-2021
Boosts immune response by clearing senescent cells; a potential treatment for COVID-19 in humansRead more...
Senolytic cocktail reduces age-related spinal disc degeneration in mice
Lifespan.io (LEAF) - 21-Sep-2021
Dasatinib and quercetin combo preserves spinal discs to target age-related back painRead more...
Longevity Technology interviews Aubrey de Grey about senolytics and other senotherapeutics
Longevity Technology - 05-Aug-2021
Most approaches have their limitations but good progress is being made on several frontsRead more...
Clearing out aged cells with senolytics can relieve jaw pain
University of Connecticut (UConn) - 07-Jul-2021
Senolytics for cartilage and bone regeneration in jaw joints, proven effective in miceRead more...
Pro-repair microenvironment after injury is favored by targeting senescent cells
News Medical - 06-Jul-2021
Senolytic drugs administration promotes locomotor and sensory recoveryRead more...