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Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

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Cellular Senescence Network (SenNet)

Consortium to comprehensively identify and characterize the differences in senescent cells across the body


Company that develops and invests in drugs and technologies which prolong human lifespan.

Rubedo Life Sciences

Extending Health Span and Reverting Age-Related Diseases.


University of Exeter spinout aiming to develop senotherapeutic interventions

SIWA Therapeutics

Biotechnology company producing therapy that targets and destroys senescent cells.

Senolytic Therapeutics (Senolytx)

Pharmaceutical company that develops a novel class of medicines by targeting damaged cells.

Cleara Biotech

Cleara is developing therapeutics to eliminate senescent cells.

UNITY Biotechnology

Biotechnology company devoted to research of restoring human health

Dorian Therapeutics

Anti-aging company developing senoblockers.

Atropos Therapeutics

Biopharmaceutical company focused on discovering and developing drugs against aging disorders and cancer.

More Senescent Cells resources

Recent News

Endurance Exercise Training May Help Prevent Accumulation of Senescent Cells in Colon Mucosa

Live Forever Club - 20-Mar-2023

Age-related increase in inflammatory markers p16 and IL-6 was not observed in endurance athletes


AKL Therapeutics’ investigational senotherapeutics drug APPA beneficial for oral osteoarthritis

Longevity Technology - 20-Mar-2023

Senescent cells have become one of the most promising targets for healthy aging research


Reversal of cell senescence using low frequency ultrasound

Live Forever Club - 27-Jan-2023

Novel therapy killed some senescent cells, rejuvenated others, without harming healthy cells


Cellular Senescence Network (SenNet) to identify and characterize senescent cells

Nature Aging - 20-Dec-2022

Grand plan includes creation of imaging datasets, new tools, techniques, and biomarker panels


Targeting senescent cells could be a useful approach for slowing/treating Alzheimer’s disease

Salk Institute - 01-Dec-2022

How senescent neurons lead to Alzheimer’s disease, effect on removal and drugs needed for therapy

More Senescent Cells News