Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
Recalibration of signalling factors to more youthful levels in the bloodLife Extension Advocacy Foundation (LEAF) - 03-Sep-2019
Adjusting the levels of just two molecules in the blood could lead to significant rejuvenationRead more...
Senolytics - Getting rid of faulty cells in bodyGuardian - 02-Sep-2019
Aims to prolong the healthspan as well as the lifespanRead more...
Nucleotides as a key element to cellular rejuvenationInteresting Engineering - 28-Jul-2019
Removing senescent cells will make us vulnerable to cancerRead more...