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Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

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Resources

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Biotechnology company devoted to research of restoring human health

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University of Exeter spinout aiming to develop senotherapeutic interventions

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Biotech company that specializes in the discovery and validation of microRNA biomarkers.

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Fast generation of functional therapeutic antibodies.

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Company that target cancer by developing senescence inducing and senolytic (senescent cell killing) compounds.

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Company that develops and invests in drugs and technologies which prolong human lifespan.

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Anti-aging company developing senoblockers.

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Biopharmaceutical company focused on discovering and developing drugs against aging disorders and cancer.

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Biotechnology company producing therapy that targets and destroys senescent cells.

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Biotechnology company focused on development of treatments for age related diseases..

More Senescent Cells resources

Recent News

Senolytic drugs improved survival rates in coronavirus-infected mice

SENS Research Foundation - 07-Oct-2021

Boosts immune response by clearing senescent cells; a potential treatment for COVID-19 in humans

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Senolytic cocktail reduces age-related spinal disc degeneration in mice

Lifespan.io (LEAF) - 21-Sep-2021

Dasatinib and quercetin combo preserves spinal discs to target age-related back pain

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Longevity Technology interviews Aubrey de Grey about senolytics and other senotherapeutics

Longevity Technology - 05-Aug-2021

Most approaches have their limitations but good progress is being made on several fronts

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Clearing out aged cells with senolytics can relieve jaw pain

University of Connecticut (UConn) - 07-Jul-2021

Senolytics for cartilage and bone regeneration in jaw joints, proven effective in mice

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Pro-repair microenvironment after injury is favored by targeting senescent cells

News Medical - 06-Jul-2021

Senolytic drugs administration promotes locomotor and sensory recovery

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