Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

Draft page - more coming soon.


Company CellAge - working with the aim to develop synthetic promoters that would be able to specifically identify senescent cells

Company Biotein - Company in the field of longevity and biotechnology that aims to provide a novel way to eradicate senescent cells.

Publisher UNITY Biotechnology - Biotechnology company devoted to research of restoring human health.

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Recent News

Senescent cell inflammatory signals as a new possible biomarker

Life Extension Advocacy Foundation (LEAF) - 29-Jun-2020

It could measure biological age and relative health


Immunotherapy as new approach to battle senescent cells

Life Extension Advocacy Foundation (LEAF) - 23-Jun-2020

Successful in mice, it may help treat many age-related disease in human


Harmful effects of senolytic drug Navitoclax in aged mice

Fight Aging! - 19-Jun-2020

Short-term treatment of this drug demonstrated cytotoxicity among other risks

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