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Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

Draft page - more coming soon.


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Leveraging the power of senolytics to eliminate senescence cells

Longevity Technology discusses senescent cells with Steve Matheson, CEO of Combilytics (YouTube)

Cellular Senescence Network (SenNet)

Consortium to comprehensively identify and characterize the differences in senescent cells across the body


Company that develops and invests in drugs and technologies which prolong human lifespan.

Rubedo Life Sciences

Extending Health Span and Reverting Age-Related Diseases.


University of Exeter spinout aiming to develop senotherapeutic interventions

SIWA Therapeutics

Biotechnology company producing therapy that targets and destroys senescent cells.

Senolytic Therapeutics (Senolytx)

Pharmaceutical company that develops a novel class of medicines by targeting damaged cells.

Cleara Biotech

Cleara is developing therapeutics to eliminate senescent cells.

UNITY Biotechnology

Biotechnology company devoted to research of restoring human health

Dorian Therapeutics

Anti-aging company developing senoblockers.

More Senescent Cells resources

Recent News

Phase I trial shows early promise in clearing senescent cells in Alzheimer's

Wake Forest Baptist Health - 07-Sep-2023

The treatment was well-tolerated with no significant changes in brain function


Senolytics have gender-specific effects on ageing in young mice (LEAF) - 30-Aug-2023

More research is needed to determine the safety and efficacy of senolytics in humans


AI identifies new senolytics that could treat age-related diseases (LEAF) - 09-Aug-2023

Three natural compounds identified, paving the way for new treatments


Experimental vaccine promises to slow down or prevent Alzheimer's in mice

American Heart Association - 30-Jul-2023

Vaccine not only reduced inflammation, but also improved behavior and awareness in mice


Tiny sea creature unlocks the secrets of healing and aging - 30-Jun-2023

Insights on the evolution of ageing and may help advance regenerative medicine

More Senescent Cells News