Senescent Cells

Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.

Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.

Draft page - more coming soon.

Recent News

Purging damaged brain stem cells can improve cognition in Alzheimer’s

National Institute on Aging - 23-May-2019

Promising results in genetically altered mice with Alzheimer’s traits

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Dr. Campisi talks about improvements in senolytics and ageing research

Life Extension Advocacy Foundation (LEAF) - 03-Apr-2019

Unlike cancer, you don't have to kill every senescent cell

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Synthetic antibodies able to target senescent cells

University of Leicester - 06-Mar-2019

nanoMIPs could improve the specificity of senolytics

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