Senescent cell clearance could be one of the big treatments to at least slow down one of the underlying causes of aging.
Senescent cells have stopped dividing and, even worse, secrete tens of biologically active proteins, including pro-inflammatory factors, proteases, pro-fibrotic factors and growth factors. This Senescence Associated Secretory Phenotype (SASP) can induce senescence in neighbouring cells and is associated with many age-related diseases.
Draft page - more coming soon.
Natural product Fisetin slows aging in miceScienceDaily - 02-Oct-2018
Fisetin reduces level of senescent cells in the body.
Senolytics staves off dementia in miceGuardian - 19-Sep-2018
Research in mice shows that senescent cells contribute to neurodegeneration.
Molecule has anti-aging effects on vascular systemMedical Xpress - 10-Sep-2018
Researchers identified a small molecule that is produced by calorie restriction.