Key points from article :
Diseases like Alzheimer’s are the result of the loss of proteostasis.
This leads to the creation of sticky misfolded proteins which form plaques.
EPFL researchers identified two key processes that act as a quality control system.
Used doxycycline and nicotinamide riboside (NR) to activate the UPRmt and mitophagy system.
Health and lifespan of worms increased dramatically and formation of plaques was reduced.
The study was published in the journal Nature.
