Join the club for FREE to access the whole archive and other member benefits.

Scientists uncover patterns of metabolism in humans across the life course

Metabolism remained same throughout the mid-life and starts to decline only at 60 years

13-Aug-2021

Key points from article :

Study of 6,400 people (age, 8-95 years) in 29 countries, suggests the metabolism remains rock solid throughout mid-life.

People's metabolism was measured using doubly labelled water.

Found four phases of metabolic life:

- birth to age one, when the metabolism shifts from being the same as the mother's to a lifetime high 50% above that of adults.

- a gentle slowdown until the age of 20.

- no change at all between the ages of 20 and 60.

- a permanent decline, with yearly falls that, by 90, leave metabolism 26% lower than in mid-life.

No metabolic surge during either puberty or pregnancy and no slowdown around the menopause.

High metabolism in the first years of life emphasise its importance in development.

It cannot be a coincidence diseases of old age kicked in as the metabolism fell.

Fully understanding the shifting metabolism could have implications in medicine.

Study from University of Wisconsin-Madison, lead by Rozalyn Anderson, published in Science.

Mentioned in this article:

Click on resource name for more details.

Rozalyn Anderson

Associate Professor at University of Wisconsin-Madison

Science

Peer-reviewed academic online journal of the American Association for the Advancement of Science (AAAS)

University of Wisconsin-Madison

Public Research university

Topics mentioned on this page:
Ageing Research