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Prime editing as a way of "editing" genes

21-Oct-2019

Key points from article :

Prime editing is used to correct damaging mutations in the lab.

Crispr-Cas9 scans the DNA and then like a microscopic pair of scissors, cuts it in two.

Prime editing is used to accurately insert or delete sections of DNA.

Challenge is to get molecular machinery capable of performing edits into the right parts of the human body.

Targeted applications will be applications in blood disorders like sickle cell or thalassemias.

Research is done by the team from the Broad Institute.

There are around 75,000 mutations caused by DNA errors and prime editing can correct 89% of them

Mentioned in this article:

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Academic

Richard Merkin Professor and Vice-Chair of the Faculty at Broad Institute of MIT and Harvard

Academia

Private Ivy League research university in Massachusetts

Academia

Private land-grant research university

Journal

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology