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Scientists reprogram fat cells to stem cells

Let's hope other stem cell treatments are closer than 15 years away

14-Jan-2021

Key points from article :

A new type of stem cell could be closer on the horizon.

"The stem cells we've developed can adapt to their surroundings and repair a range of damaged tissues," - John Pimand, senior author.

Human fat cells were exposed to a compound mixture that caused the cells to lose their original identity.

Reprogrammed these cells using two drugs - azacitidine (blood cancer) and a growth facto.

Human iMS(induced multipotent stem cells) were injected into mice - repaired tissues after injury.

They are made from a patient's own cells, which reduces the risk of rejection.

Existing technologies transform cells into stem cells but have key limitations.

Researchers are mindful that potential translation to human therapies is still a long way away.

Research by University of New South Wales published in Science Advances.

Mentioned in this article:

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John Pimanda

Haematologist and Professor at UNSW.

Science Advances

Journal that publishes original research and reviews in all disciplines of science

University of New South Wales (UNSW)

Public Research university

Topics mentioned on this page:
Stem Cells