Key points from article :
Human trials with stem cell transplants have been shown to reduce age-related frailty.
CRATUS is a series of stem cell studies involving transplanting mesenchymal stem cells.
The presence of MSCs appears to reduce the background of chronic age-related inflammation.
Phase 1 results showed that MSC therapy is well tolerated.
Phase 2 saw improvement in 6-minute walking test and lung function.
Blood levels of inflammatory TNF-α and activated T-cells were reduced significantly.
The study was published in Frontiers in Nutrition.
