Key points from article :
Aging is accompanied by a chronic, smoldering background of inflammation known as inflammaging.
Detrimental changes to our gut microbiome may be major drivers of systemic inflammation.
Microbiome helps to control pathogenic bacteria, protects from invaders and maintains the intestinal barrier.
Knowledge has been accumulating on the relationship between gut microbiome and brain functions.
Significant quantitative and qualitative changes of gut microbiome have been reported in Alzheimer’s disease patients.
Gut microbiome is also highly sensitive to negative external lifestyle aspects.
These are also considered as important risk factors for the development of sporadic Alzheimer’s disease.
Gut and oral microbiome is capable of modulating the neurochemical and neuro-metabolic signaling pathways of the brain.
Further study could unearth novel associations between intestinal microbiome, lifestyle, and dementia.
Research by Nazarbayev University published in Frontiers in Cellular and Infection Microbiology.
