Key points from article :
- Immune system continuously declines with the progression of age which results in frailty
-Frailty negatively impacts the quality of life.
- This has led researchers to identify new approaches to improve health-span in the aging population.
-Chronic low-grade inflammation is known to accelerate the aging processes
-Visceral adipose tissue, known as belly fat, crucially contributes to the development of chronic low-grade inflammation
-Immune cells such as Eosinophils in the belly fat help regulate chronic low-grade inflammation and reverse aging processes.
-With increasing age, the frequency of eosinophils in belly fat declines, and belly fat turns into a source of pro-inflammatory mediators.
-Studies showed that the transfer of eosinophils reduced inflammation and improved vaccination responses, not only in mice but also in humans.
-The future direction for research involves using the gained knowledge for the establishment of therapeutic approaches to promote healthy aging in humans.
