Key points from article :
David Sinclair is a prominent ageing researcher and is known for his book "Lifespan" and his advocacy for life extension.
Sinclair's Information Theory of Aging proposes that aging is caused by the loss of epigenetic information in cells.
Epigenetic information controls which genes are expressed and how cells function.
Suggests that a backup copy stores information about the cell’s youthful state, which could potentially reset epigenetic state.
While the theory is intriguing, the exact location and mechanism for accessing this backup copy are still under investigation.
Believes that a "whole-body epigenetic reset" may be possible in the future.
Sinclair sees promise in senolytics, epigenetic reprogramming, and AI for future longevity interventions.
Findings in support of the theory was published in the journal Cell.
