Key points from article :
A global team of scientists argued that it’s high time we turn from worm to human.
The key to human longevity, they say, lies in the genes of centenarians.
From this rare valuable population, we can gain “insight into the physiology of healthy ageing."
"And the development of new therapies to extend the human healthspan.”
The offspring of centenarians also have lower chances of age-related diseases.
And exhibit a more “youthful” profile of metabolism and age-related inflammation.
About 25-35 % of the variability in how long people live is determined by their genes.
Centenarian genes contain a biological blueprint for healthy aging and longevity
Guided by these genes and validated by animal models of ageing, we can design powerful drugs.
Drugs that sever the connection between the genes and proteins that drive ageing.
Published in Nature Metabolism August issue.
