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False Positives in Senescent Cell Detection

19-Aug-2017

Key points from article :

Researchers commonly determine the presence of senescent cells through the use of the p16ink4a (p16) and ?-galactosidase biomarkers.

May not be the only cells that exhibit both of these biomarkers.

Therapies target these too, removing cells that are not senescent.

Oisin Biotechnology  does use p16 as a target biomarker.

Benefits may outweigh risk of removing non-senescent cells.

The studies were published in the Aging and Nature journals.

Mentioned in this article:

Click on resource name for more details.

Aging

Bio-medical journal covering research on all aspects of gerontology

Nature

Scientific journal covering research from a variety of academic disciplines, mostly in science and technology

Oisin Biotechnologies

Drug development company focused on the senolytic technology to fight age-related diseases

Topics mentioned on this page:
Senescent Cells