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Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression

TPE causes systematic rejuvenation in human body by influencing multiple factors

25-Aug-2022

Key points from article :

Conboy lab has confirmed that plasma dilution leads to systemic rejuvenation against multiple proteomic aspects of aging in human beings.

A total of ten proteins were found to be useful as biomarkers under this analysis.

This paper focuses on therapeutic plasma exchange (TPE), a procedure that simply replaces blood plasma with saline solution and albumin.

Once a month, a total of eight people had their blood biomarkers assessed and were then given TPE. 

They compared the blood serum of young and old control donors.

They then performed a bioinformatics analysis through the Kyoto Encylopedia of Genes and Genomes (KEGG). 

Only eight people were in the treatment group of this study.

TPE stabilizes and modulates blood proteins, reduces dangerous proteins associated with neurodegeneration and cancer, rejuvenates multiple markers of gene expression, and reduces inflammaging. 

The study was published in GeroScience.

Mentioned in this article:

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GeroScience

International, peer-reviewd journal of the American Aging Association published 2 times per month

The Conboy Laboratory

Research laboratory based in UC Berkeley developing solutions to slow down ageing

Topics mentioned on this page:
Young Blood, Rejuvenation
Therapeutic plasma exchange (TPE) rejuvenates multiple markers of gene expression