Key points from article :
Initial source of age-related inflammation could be gut microbiota.
As we age the gut microbiota increasingly favors pro-inflammatory activity.
When kept in a germ-free environment mice did not show any increase in age-related circulating pro-inflammatory cytokines.
Age-associated changes to the microbiota can be reversed by reducing the level of TNF circulating in the system.
The study was published in the Cell Host & Microbe journal.
