Rate of shortening, shape and method of testing are all important factors
Lots of interest currently into relationship of telomere length on aging - or vice versa.
Telomeres are a region of repetitive nucleotide sequences at the end of chromosone which reduce in length over time - therefore hinting they may be involved in the aging prcess, i.e. length reduces to zero and cell blows up (I'm simplifying slightly!)
Click on resource name for more details.
The Telomere Effect written by Elissa Epel and Elizabeth Blackburn will make you reassess how you live your life on a day-to-day basis
Researchers found a missing genetic link that helps melanoma cells defeat mortality
EurekAlert! - 10-Nov-2022
Mutations in a telomere binding protein provide a new approach to treat melanoma and other cancersRead more...
Excessive alcohol consumption may age you faster by accelerating your biological age
Interesting Engineering - 28-Jul-2022
Alcohol consumption causes telomere shortening, leading to several age-related diseasesRead more...
New insight on the accumulation of senescent cells in humans
UPMC - 30-Jun-2022
Oxidative DNA damage induce rapid senescence compared with shorter telomeres from repeated cell divisionsRead more...
Lifespan of middle-aged mice increased by a third with telomerase gene therapy
CISION PR Newswire - 19-May-2022
Treatment used proprietary CMV vector which is able to deliver multiple genes into the nucleusRead more...
Viral-vector gene therapies could unlock healthy life extension in humans
Lifespan.io (LEAF) - 12-May-2022
Lifespan of mice greatly extended even when treatment only started at the equivalent of 56 years oldRead more...