Key points from article :
Researchers at the Arc Institute in California have developed a new gene editing technique called "bridge editing" that could potentially surpass CRISPR in its ability to alter DNA.
Bridge editing, discovered in bacteria, allows for the alteration of large sections of the genome, potentially enabling the reshaping of entire genomes.
Unlike CRISPR, which primarily disrupts genes, bridge editing allows for precise additions, deletions, or reversals of DNA sequences without leaving behind extra DNA fragments (scars).
This method is guided by RNA, similar to CRISPR, but uniquely targets two DNA sequences: one for alteration and another specifying the DNA to be changed.
Bridge editing has been successfully demonstrated in bacterial cells and test tubes, but its effectiveness in complex human cells is yet to be determined.
The research findings open up new possibilities for advanced genome editing, potentially impacting fields like medicine and agriculture.
