Key points from article :
Reliable and fast ways to assess biological age are needed to determine the outcome of potential interventions.
Lifespan studies are most reliable but this is costly and time-consuming.
Monocyte chemoattractant protein MCP-1/CCL2 is an important chemokine.
It recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation.
Circulating MCP-1 increased in an age-dependent manner in wild-type mice.
In humans with aortic stenosis, MCP-1 levels were significantly higher in frail individuals.
The study was published in the Aging Cell journal.
