Key points from article :
Mitochondria communicates with nucleus and trigger senescence causing cellular ageing.
An FDA-approved drug currently used to treat cancer can restore senescent cells to their youth.
HDAC inhibitor-treatment caused less inflammatory signals and better mitochondrial function.
But it's too toxic to use in healthy individuals just to prevent disease.
This study firmly links dysfunctional mitochondria, inflammation and senescent cells to ageing.
Needs to screen for less toxic senescence-inhibiting drugs.
A collaborative research published in Genes & Development.
